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2058-52-8,MFCD00866705
Catalog No.:AA002AAV

2058-52-8 | Dibenzo[b,f][1,4]thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-

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5mg
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1 week  
$304.00   $213.00
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10mg
99%
1 week  
$463.00   $324.00
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25mg
99%
1 week  
$876.00   $613.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002AAV
Chemical Name:
Dibenzo[b,f][1,4]thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
CAS Number:
2058-52-8
Molecular Formula:
C18H18ClN3S
Molecular Weight:
343.8736
MDL Number:
MFCD00866705
SMILES:
CN1CCN(CC1)C1=Nc2ccccc2Sc2c1cc(Cl)cc2
Properties
Computed Properties
 
Complexity:
450  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
3.6  

Literature

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Journal: Archives of toxicology 20171201

Title: Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses.

Journal: The Cochrane database of systematic reviews 20120101

Title: [The usefulness of SPECT with 123I-ioflupane (DaTSCAN) in Parkinsonism induced by pharmaceuticals].

Journal: Revista de neurologia 20110316

Title: Interaction of clozapine and its nitrenium ion with rat D2 dopamine receptors: in vitro binding and computational study.

Journal: Journal of computer-aided molecular design 20110201

Title: Management of Huntington's disease: role of tetrabenazine.

Journal: Therapeutics and clinical risk management 20110101

Title: Antidepressant and antipsychotic use in an Italian pediatric population.

Journal: BMC pediatrics 20110101

Title: Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways.

Journal: PloS one 20110101

Title: Use of antipsychotic and antidepressant within the Psychiatric Disease Centre, Regional Health Service of Ferrara.

Journal: BMC clinical pharmacology 20110101

Title: Radiopaque stomach contents in postmortem CT in suicidal oral medication intoxication: report of three cases.

Journal: Journal of forensic and legal medicine 20100401

Title: Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28.

Journal: Bioorganic & medicinal chemistry 20100115

Title: A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting.

Journal: Annals of general psychiatry 20100101

Title: Baseline characteristics and initial treatment decisions for patients with schizophrenia at risk of treatment nonadherence.

Journal: Patient preference and adherence 20100101

Title: Relationship between obesity and antipsychotic drug use in the adult population: a longitudinal, retrospective claim database study in Primary Care settings.

Journal: Neuropsychiatric disease and treatment 20080201

Title: Determination and distribution of clotiapine (Entumine) in human plasma, post-mortem blood and tissue samples from clotiapine-treated patients and from autopsy cases.

Journal: Forensic science international 20070806

Title: Simultaneous analysis of classical neuroleptics, atypical antipsychotics and their metabolites in human plasma.

Journal: Analytical and bioanalytical chemistry 20070501

Title: Risk of extrapyramidal syndrome in schizophrenic patients treated with antipsychotics: a population-based study.

Journal: Clinical pharmacology and therapeutics 20070401

Title: Determination of several psychiatric drugs in whole blood using capillary gas-liquid chromatography with nitrogen phosphorus detection: comparison of two solid phase extraction procedures.

Journal: Forensic science international 20051220

Title: Clotiapine compared with chlorpromazine in chronic schizophrenia.

Journal: Schizophrenia research 20051215

Title: Clotiapine for acute psychotic illnesses.

Journal: The Cochrane database of systematic reviews 20041018

Title: Unusual compulsive motor activity during treatment with clothiapine in a mentally retarded adolescent.

Journal: Brain & development 20040901

Title: Optimization and validation of a capillary zone electrophoretic method for the simultaneous analysis of four atypical antipsychotics.

Journal: Journal of chromatography. A 20040416

Title: A simple high-performance liquid chromatographic method for detection of hydroxyzine in human plasma after overdose.

Journal: Journal of pharmacological and toxicological methods 20040101

Title: Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses.

Journal: The Cochrane database of systematic reviews 20040101

Title: Neuroleptic malignant syndrome in a child treated with an atypical antipsychotic.

Journal: Journal of toxicology. Clinical toxicology 20040101

Title: TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243].

Journal: BMC psychiatry 20020101

Title: [State of lucid delirium after orthotopic liver transplantation. Clinical case].

Journal: Chirurgia italiana 20020101

Title: Psychosis in children: diagnosis and treatment.

Journal: Dialogues in clinical neuroscience 20010601

Title: Clotiapine for acute psychotic illnesses.

Journal: The Cochrane database of systematic reviews 20010101

Title: Quantitative opioid withdrawal signs in rats: effects exerted by clothiapine administration.

Journal: Fundamental & clinical pharmacology 19970101

Title: Choreiform syndrome associated with fluoxetine treatment in a patient with deficient CYP2D6 activity.

Journal: Neurology 19960301

Title: Catatonia: harbinger of the neuroleptic malignant syndrome.

Journal: The British journal of psychiatry : the journal of mental science 19910301

Title: Toren P, et al. Case study: emergence of transient compulsive symptoms during treatment with clothiapine. J Am Acad Child Adolesc Psychiatry. 1995;34(11):1469-1472.

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Tags:2058-52-8 Molecular Formula|2058-52-8 MDL|2058-52-8 SMILES|2058-52-8 Dibenzo[b,f][1,4]thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-