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20638-84-0
Catalog No.:AA002IET

20638-84-0 | retinamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
4 weeks  
$492.00   $344.00
- +
2mg
4 weeks  
$804.00   $563.00
- +
5mg
4 weeks  
$1,483.00   $1,038.00
- +
10mg
4 weeks  
$2,375.00   $1,663.00
- +
25mg
4 weeks  
$4,608.00   $3,225.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002IET
Chemical Name:
retinamide
CAS Number:
20638-84-0
Molecular Formula:
C20H29NO
Molecular Weight:
299.4504
SMILES:
C/C(=C\C=C\C(=C\C(=O)N)\C)/C=C/C1=C(C)CCCC1(C)C
Properties
Computed Properties
 
Complexity:
569  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
5.6  

Literature

Title: Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress.

Journal: Neoplasia (New York, N.Y.) 20140901

Title: Effects of novel all-trans retinoic acid retinamide derivatives on the proliferation and apoptosis of human lung adenocarcinoma cell line A549 cells.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

Title: Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts.

Journal: Neuroscience 20090929

Title: Quantitative determination and pharmacokinetics of retinamido-ester in rat plasma by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20081001

Title: Novel cell death pathways induced by N-(4-hydroxyphenyl)retinamide: therapeutic implications.

Journal: Molecular cancer therapeutics 20070101

Title: Porphyrin-retinamides: synthesis and cellular studies.

Journal: Bioconjugate chemistry 20070101

Title: Retinamide-induced apoptosis in glioblastomas is associated with down-regulation of Bcl-xL and Bcl-2 proteins.

Journal: Journal of neuro-oncology 20050901

Title: Fenretinide stimulates redox-sensitive ceramide production in breast cancer cells: potential role in drug-induced cytotoxicity.

Journal: British journal of cancer 20041115

Title: Synthesis and biological activity of novel retinamide and retinoate derivatives.

Journal: Chemical & pharmaceutical bulletin 20040501

Title: Hydrolysis of 4-HPR to atRA occurs in vivo but is not required for retinamide-induced apoptosis.

Journal: Archives of biochemistry and biophysics 20031115

Title: Potent cytotoxic effects of novel retinamide derivatives in ovarian cancer cells.

Journal: Biological & pharmaceutical bulletin 20031001

Title: Breast tissue accumulation of retinamides in a randomized short-term study of fenretinide.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701

Title: Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010601

Title: Effects of novel phenylretinamides on cell growth and apoptosis in bladder cancer.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010401

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