20662-53-7,MFCD00005714
Catalog No.:AA0037SH

20662-53-7 | 4-(2-Keto-1-benzimidazolinyl)piperidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$31.00   $22.00
- +
1g
98%
in stock  
$80.00   $56.00
- +
5g
98%
in stock  
$286.00   $200.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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Technical Information
Catalog Number:
AA0037SH
Chemical Name:
4-(2-Keto-1-benzimidazolinyl)piperidine
CAS Number:
20662-53-7
Molecular Formula:
C12H15N3O
Molecular Weight:
217.2670
MDL Number:
MFCD00005714
SMILES:
O=c1[nH]c2c(n1C1CCNCC1)cccc2
Properties
Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.5  

Literature

Title: Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.

Journal: Journal of medicinal chemistry 20160225

Title: Synthesis and antibacterial activities of 1-alkyl-3-methacryloyl (acryloyl) of benzimidazolone (thione) derivatives.

Journal: International journal of molecular sciences 20120101

Title: Effect of nitro groups on the photo physical properties of benzimidazolone: a solvatochromic study.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111215

Title: Benzimidazolone as potent chymase inhibitor: modulation of reactive metabolite formation in the hydrophobic (P1) region.

Journal: Bioorganic & medicinal chemistry letters 20110801

Title: N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents.

Journal: Bioorganic & medicinal chemistry 20090815

Title: Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity.

Journal: Bioorganic & medicinal chemistry letters 20090401

Title: Structures of six industrial benzimidazolone pigments from laboratory powder diffraction data.

Journal: Acta crystallographica. Section B, Structural science 20090401

Title: Benzimidazolone-based serotonin 5-HT1A or 5-HT7R ligands: synthesis and biological evaluation.

Journal: Bioorganic & medicinal chemistry letters 20090315

Title: Potent benzimidazolone-based CGRP receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20081201

Title: The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Towards the synthesis of new benzimidazolone derivatives with surfactant properties.

Journal: Carbohydrate research 20080225

Title: Structural elucidation of rabeprazole sodium photodegradation products.

Journal: Journal of pharmaceutical and biomedical analysis 20080107

Title: New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.

Journal: Bioorganic & medicinal chemistry letters 20071201

Title: Potent benzimidazolone based human beta(3)-adrenergic receptor agonists.

Journal: Bioorganic & medicinal chemistry letters 20061101

Title: The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20060415

Title: Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures.

Journal: Mini reviews in medicinal chemistry 20060101

Title: Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.

Journal: Journal of medicinal chemistry 20050908

Title: SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20050801

Title: Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity.

Journal: Bioorganic & medicinal chemistry letters 20050602

Title: Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20050315

Title: Multiple tandem mass spectrometry-based investigation of the behaviour of some thiazol-benzimidazolones and 2-benzimidazolylsulfanyl ethanones.

Journal: European journal of mass spectrometry (Chichester, England) 20050101

Title: Natural modulators of large-conductance calcium-activated potassium channels.

Journal: Planta medica 20031001

Title: CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.

Journal: American journal of physiology. Lung cellular and molecular physiology 20030701

Title: In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin.

Journal: Journal of clinical psychopharmacology 20020401

Title: Rapid liquid-phase combinatorial synthesis of heterocyclic libraries.

Journal: Methods in molecular biology (Clifton, N.J.) 20020101

Title: Synthesis and progesterone receptor antagonist activities of 6-aryl benzimidazolones and benzothiazolones.

Journal: Bioorganic & medicinal chemistry letters 20011022

Title: N-acylated alpha-(3-pyridylmethyl)-beta-aminotetralin antagoinists of the human neuropeptide Y Y5 receptor.

Journal: Bioorganic & medicinal chemistry letters 20000807

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SDS
Tags:20662-53-7 Molecular Formula|20662-53-7 MDL|20662-53-7 SMILES|20662-53-7 4-(2-Keto-1-benzimidazolinyl)piperidine
Catalog No.: AA0037SH
20662-53-7,MFCD00005714
20662-53-7 | 4-(2-Keto-1-benzimidazolinyl)piperidine
Pack Size: 250mg
Purity: 98%
in stock
$31.00 $22.00
Pack Size: 1g
Purity: 98%
in stock
$80.00 $56.00
Pack Size: 5g
Purity: 98%
in stock
$286.00 $200.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0037SH
Chemical Name: 4-(2-Keto-1-benzimidazolinyl)piperidine
CAS Number: 20662-53-7
Molecular Formula: C12H15N3O
Molecular Weight: 217.2670
MDL Number: MFCD00005714
SMILES: O=c1[nH]c2c(n1C1CCNCC1)cccc2
Properties
Complexity: 275  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 16  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.5  
Literature fold

Title: Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.

Journal: Journal of medicinal chemistry20160225

Title: Synthesis and antibacterial activities of 1-alkyl-3-methacryloyl (acryloyl) of benzimidazolone (thione) derivatives.

Journal: International journal of molecular sciences20120101

Title: Effect of nitro groups on the photo physical properties of benzimidazolone: a solvatochromic study.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20111215

Title: Benzimidazolone as potent chymase inhibitor: modulation of reactive metabolite formation in the hydrophobic (P1) region.

Journal: Bioorganic & medicinal chemistry letters20110801

Title: N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors.

Journal: Bioorganic & medicinal chemistry letters20101215

Title: Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents.

Journal: Bioorganic & medicinal chemistry20090815

Title: Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity.

Journal: Bioorganic & medicinal chemistry letters20090401

Title: Structures of six industrial benzimidazolone pigments from laboratory powder diffraction data.

Journal: Acta crystallographica. Section B, Structural science20090401

Title: Benzimidazolone-based serotonin 5-HT1A or 5-HT7R ligands: synthesis and biological evaluation.

Journal: Bioorganic & medicinal chemistry letters20090315

Title: Potent benzimidazolone-based CGRP receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters20081201

Title: The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives.

Journal: Bioorganic & medicinal chemistry letters20080601

Title: Towards the synthesis of new benzimidazolone derivatives with surfactant properties.

Journal: Carbohydrate research20080225

Title: Structural elucidation of rabeprazole sodium photodegradation products.

Journal: Journal of pharmaceutical and biomedical analysis20080107

Title: New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.

Journal: Bioorganic & medicinal chemistry letters20071201

Title: Potent benzimidazolone based human beta(3)-adrenergic receptor agonists.

Journal: Bioorganic & medicinal chemistry letters20061101

Title: The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors.

Journal: Bioorganic & medicinal chemistry letters20060415

Title: Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures.

Journal: Mini reviews in medicinal chemistry20060101

Title: Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.

Journal: Journal of medicinal chemistry20050908

Title: SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters20050801

Title: Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity.

Journal: Bioorganic & medicinal chemistry letters20050602

Title: Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.

Journal: Bioorganic & medicinal chemistry letters20050315

Title: Multiple tandem mass spectrometry-based investigation of the behaviour of some thiazol-benzimidazolones and 2-benzimidazolylsulfanyl ethanones.

Journal: European journal of mass spectrometry (Chichester, England)20050101

Title: Natural modulators of large-conductance calcium-activated potassium channels.

Journal: Planta medica20031001

Title: CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.

Journal: American journal of physiology. Lung cellular and molecular physiology20030701

Title: In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin.

Journal: Journal of clinical psychopharmacology20020401

Title: Rapid liquid-phase combinatorial synthesis of heterocyclic libraries.

Journal: Methods in molecular biology (Clifton, N.J.)20020101

Title: Synthesis and progesterone receptor antagonist activities of 6-aryl benzimidazolones and benzothiazolones.

Journal: Bioorganic & medicinal chemistry letters20011022

Title: N-acylated alpha-(3-pyridylmethyl)-beta-aminotetralin antagoinists of the human neuropeptide Y Y5 receptor.

Journal: Bioorganic & medicinal chemistry letters20000807

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