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2068-78-2,MFCD08706469
Catalog No.:AA002IMG

2068-78-2 | Vincaleukoblastine, 22-oxo-, sulfate (1:1)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$58.00   $40.00
- +
10mg
≥95%
in stock  
$109.00   $76.00
- +
25mg
98%
in stock  
$172.00   $120.00
- +
50mg
95%(HPLC)
in stock  
$291.00   $204.00
- +
100mg
98%
in stock  
$438.00   $307.00
- +
250mg
95%(HPLC)
in stock  
$1,081.00   $757.00
- +
500mg
98%
in stock  
$1,770.00   $1,239.00
- +
1g
98%
in stock  
$3,140.00   $2,198.00
- +
5g
98%
in stock  
$13,922.00   $9,745.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002IMG
Chemical Name:
Vincaleukoblastine, 22-oxo-, sulfate (1:1)
CAS Number:
2068-78-2
Molecular Formula:
C46H58N4O14S
Molecular Weight:
923.0361
MDL Number:
MFCD08706469
SMILES:
OS(=O)(=O)O.O=CN1c2cc(OC)c(cc2[C@]23[C@@H]1[C@@](O)(C(=O)OC)[C@H](OC(=O)C)[C@]1([C@@H]3N(CC2)CC=C1)CC)[C@]1(C[C@@H]2CN(CCc3c1[nH]c1c3cccc1)C[C@](C2)(O)CC)C(=O)OC
NSC Number:
67574
UN Number:
1544
Properties
Computed Properties
 
Complexity:
1830  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
65  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
10  

Literature

Title: Jordan, M.A., et al. Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res, 1985. 45(6): p. 2741-7.

Title: Gidding, C.E., et al, Vincristine revisited. Crit Rev Oncol Hematol, 1999. 29(3): p. 267-87.

Title: Donoso, J.A., et al, Action of the vinca alkaloids vincristine, vinblastine, and desacetyl vinblastine amide on axonal fibrillar organelles in vitro. Cancer Res, 1977. 37(5): p. 1401-7.

Title: Horton, J.K., et al. Relationships between tumor responsiveness, vincristine pharmacokinetics and arrest of mitosis in human tumor xenografts. Biochem Pharmacol, 1988. 37(20): p. 3995-4000.

Title: Baguley, B.C., et al, Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism. Eur J Cancer, 1991. 27(4): p. 482-7.

Title: Zhang D, et al. Co-delivery nanoparticles with characteristics of intracellular precision release drugs for overcoming multidrug resistance. Int J Nanomedicine. 2017 Mar 16;12:2081-2108.

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SDS
Tags:2068-78-2 Molecular Formula|2068-78-2 MDL|2068-78-2 SMILES|2068-78-2 Vincaleukoblastine, 22-oxo-, sulfate (1:1)