Home Deuterated Building Blocks 2083627-02-3
2083627-02-3,MFCD30738018
Catalog No.:AA01DDIU

2083627-02-3 | MAK683

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$17.00   $12.00
- +
5mg
98%
in stock  
$42.00   $29.00
- +
10mg
98%
in stock  
$63.00   $44.00
- +
25mg
98%
in stock  
$106.00   $75.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DDIU
Chemical Name:
MAK683
CAS Number:
2083627-02-3
Molecular Formula:
C17H15N5O3S
Molecular Weight:
369.3977
MDL Number:
MFCD30738018
SMILES:
CS(=O)(=O)c1ccc(cc1)c1cnc(n2c1nnc2)NCc1ccco1
Properties
Computed Properties
 
Complexity:
575  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
2.3  

Literature

Title: Li L, et al. Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED. PLoS One. 2017 Jan 10;12(1):e0169855.

Title: Huang Y, et al. Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy. J Med Chem. 2017 Mar 23;60(6):2215-2226.

Title: Qi W, et al. An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED. Nat Chem Biol. 2017 Apr;13(4):381-388.

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SDS
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