+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Amines 2095719-92-7
2095719-92-7,MFCD32874105
Catalog No.:AA01LI88

2095719-92-7 | (αR)-6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-α-methyl-1-oxo-2H-isoindole-2-acetamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$32.00   $22.00
- +
5mg
98%
in stock  
$55.00   $39.00
- +
25mg
98%
in stock  
$152.00   $107.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01LI88
Chemical Name:
(αR)-6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-α-methyl-1-oxo-2H-isoindole-2-acetamide
CAS Number:
2095719-92-7
Molecular Formula:
C29H31ClFN5O5
Molecular Weight:
584.0383
MDL Number:
MFCD32874105
SMILES:
COc1cc(F)cc(c1)[C@H](NC(=O)[C@H](N1Cc2c(C1=O)cc(cc2)c1nc(ncc1Cl)NC1CCOCC1)C)CO
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:SYGNATUREDISCOVERYLTD;OTSUKAHOLDINGSCOLTD-WO2017/68412,2017,A1Locationinpatent:Page/Pagecolumn666;667

[2]Heightman,TomD.;Berdini,Valerio;Bevan,Luke;Buck,IldikoM.;Carr,MariaG.;Courtin,Aurélie;Coyle,JosephE.;Day,JamesE.H.;East,Charlotte;Fazal,Lynsey;Griffiths-Jones,CharlotteM.;Howard,Steven;Kucia-Tran,Justyna;Martins,Vanessa;Muench,Sandra;Munck,JoanneM.;Norton,David;O'Reilly,Marc;Palmer,Nicholas;Pathuri,Puja;Peakman,TorrenM.;Reader,Michael;Rees,DavidC.;Rich,SharnaJ.;Shah,Alpesh;Wallis,NicolaG.;Walton,Hugh;Wilsher,NicolaE.;Woolford,AlisonJ.-A.;Cooke,Michael;Cousin,David;Onions,Stuart;Shannon,Jonathan;Watts,John;Murray,ChristopherW.[JournalofMedicinalChemistry,2021,vol.64,#16,p.12286-12303]

[3]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2018/193410,2018,A1Locationinpatent:Page/Pagecolumn75;76

[4]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1Locationinpatent:Paragraph0147-0151

[5]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1Locationinpatent:Paragraph0147-0151

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2018/193410,2018,A1

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2018/193410,2018,A1

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2018/193410,2018,A1

[2]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1

[3]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1

[4]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2018/193410,2018,A1

[2]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1

[3]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2022/259222,2022,A1

Literature

Title: Michael Reader, et al. 6-pyrimidin-isoindole derivative as erk1/2 inhibitor. WO2018193410A1.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 2095719-92-7
2095719-90-5

2095719-90-5
Building Blocks
More >
Tags:2095719-92-7 Molecular Formula|2095719-92-7 MDL|2095719-92-7 SMILES|2095719-92-7 (αR)-6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-α-methyl-1-oxo-2H-isoindole-2-acetamide