Title: Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold.
Journal: Bioorganic & medicinal chemistry letters 20070401
Title: Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia.
Journal: Cancer biotherapy & radiopharmaceuticals 20061001
Title: Dissociation of I domain and global conformational changes in LFA-1: refinement of small molecule-I domain structure-activity relationships.
Journal: Biochemistry 20050322
Title: Total synthesis of LFA-1 antagonist BIRT-377 via organocatalytic asymmetric construction of a quaternary stereocenter.
Journal: Organic letters 20050303
Title: The functional interaction of the beta 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20041115
Title: Second-generation lymphocyte function-associated antigen-1 inhibitors: 1H-imidazo[1,2-alpha]imidazol-2-one derivatives.
Journal: Journal of medicinal chemistry 20041021
Title: Selective in vivo growth of lymphocyte function- associated antigen-1-positive murine myeloma cells. Involvement of function-associated antigen-1-mediated homotypic cell-cell adhesion.
Journal: Experimental hematology 20030101
Title: The role of leukocyte function-associated antigen-1 in animal models of inflammation.
Journal: European journal of pharmacology 20011019
Title: An improved synthesis of chiral alpha-(4-bromobenzyl)alanine ethyl ester and its application to the synthesis of LFA-1 antagonist BIRT-377.
Journal: The Journal of organic chemistry 20010309
Title: Cutting edge: a small molecule antagonist of LFA-1-mediated cell adhesion.
Journal: Journal of immunology (Baltimore, Md. : 1950) 19991115
