[1]Lin,Jinshun;Jin,Xiuli;Bu,Yiwen;Cao,Deliang;Zhang,Nannan;Li,Shangfu;Sun,Qinsheng;Tan,Chunyan;Gao,Chunmei;Jiang,Yuyang[OrganicandBiomolecularChemistry,2012,vol.10,#48,p.9734-9746]
[1]Lin,Jinshun;Jin,Xiuli;Bu,Yiwen;Cao,Deliang;Zhang,Nannan;Li,Shangfu;Sun,Qinsheng;Tan,Chunyan;Gao,Chunmei;Jiang,Yuyang[OrganicandBiomolecularChemistry,2012,vol.10,#48,p.9734-9746]
[1]Lin,Jinshun;Jin,Xiuli;Bu,Yiwen;Cao,Deliang;Zhang,Nannan;Li,Shangfu;Sun,Qinsheng;Tan,Chunyan;Gao,Chunmei;Jiang,Yuyang[OrganicandBiomolecularChemistry,2012,vol.10,#48,p.9734-9746]
[1]Lin,Jinshun;Jin,Xiuli;Bu,Yiwen;Cao,Deliang;Zhang,Nannan;Li,Shangfu;Sun,Qinsheng;Tan,Chunyan;Gao,Chunmei;Jiang,Yuyang[OrganicandBiomolecularChemistry,2012,vol.10,#48,p.9734-9746]
[1]Lin,Jinshun;Jin,Xiuli;Bu,Yiwen;Cao,Deliang;Zhang,Nannan;Li,Shangfu;Sun,Qinsheng;Tan,Chunyan;Gao,Chunmei;Jiang,Yuyang[OrganicandBiomolecularChemistry,2012,vol.10,#48,p.9734-9746]
Title: Drug resistance to inhibitors of the human double minute-2 E3 ligase is mediated by point mutations of p53, but can be overcome with the p53 targeting agent RITA.
Journal: Molecular cancer therapeutics 20121001
Title: Chk2 mediates RITA-induced apoptosis.
Journal: Cell death and differentiation 20120601
Title: Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.
Journal: Cell death & disease 20120401
Title: Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma.
Journal: Oncogene 20120301
Title: Inability of p53-reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient in p53Ser46 phosphorylation.
Journal: Biochemical and biophysical research communications 20120120
Title: Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.
Journal: PloS one 20120101
Title: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1.
Journal: Cell death & disease 20110501
Title: p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma.
Journal: Oral oncology 20110101
Title: HIPK2 regulation by MDM2 determines tumor cell response to the p53-reactivating drugs nutlin-3 and RITA.
Journal: Cancer research 20090801
Title: Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells.
Journal: Molecular pharmaceutics 20081006
Title: Mutated and non-mutated TP53 as targets in the treatment of leukaemia.
Journal: British journal of haematology 20080501
Title: Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs.
Journal: International journal of pharmaceutics 20080303
Title: The ubiquitin system, disease, and drug discovery.
Journal: BMC biochemistry 20080101
Title: Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer.
Journal: Theoretical biology & medical modelling 20050101
Title: Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.
Journal: Nature medicine 20041201
Title: Identification of the major metabolite of 2,5-bis(5-hydroxymethyl-2-thienyl)furan (NSC 652287), an antitumor agent, in the S9 subcellular fraction of dog liver cells.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020205
Title: Issaeva N, et al. Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nat Med. 2004 Dec;10(12):1321-8. Epub 2004 Nov 21.
Title: Nieves-Neira W, et al. DNA protein cross-links produced by NSC 652287, a novel thiophene derivative active against human renal cancer cells. Mol Pharmacol. 1999 Sep;56(3):478-84.
Title: Zhao CY, et al. Rescue of p53 function by small-molecule RITA in cervical carcinoma by blocking E6-mediated degradation. Cancer Res. 2010 Apr 15;70(8):3372-81.
