Home Fluorides 2135-17-3
2135-17-3,MFCD00056464
Catalog No.:AA00I417

2135-17-3 | Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-

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50mg
≥98%
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100mg
≥ 99% (HPLC)
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$92.00   $64.00
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250mg
≥ 99% (HPLC)
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$163.00   $114.00
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1g
≥ 99% (HPLC)
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5g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I417
Chemical Name:
Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-
CAS Number:
2135-17-3
Molecular Formula:
C22H28F2O5
Molecular Weight:
410.4515
MDL Number:
MFCD00056464
SMILES:
OCC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)C1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F
Properties
Computed Properties
 
Complexity:
839  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
1.9  

Literature

Title: Development of QuEChERS-based extraction and liquid chromatography-tandem mass spectrometry method for quantifying flumethasone residues in beef muscle.

Journal: Meat science 20121201

Title: Clinical efficacy of flumetasone/salicylic acid ointment combined with 308-nm excimer laser for treatment of psoriasis vulgaris.

Journal: Photodermatology, photoimmunology & photomedicine 20120601

Title: Intra-antral application of an anti-fungal agent for recurrent maxillary fungal rhinosinusitis: a case report.

Journal: Journal of medical case reports 20120101

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Validation of a multi-residue enzyme-linked immunosorbent assay for qualitative screening of corticosteroids in liver, urine and milk.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110901

Title: Tympanoplasty graft preparation using ear drops containing polyethylene glycol, flumethasone and clioquinol.

Journal: The Journal of laryngology and otology 20110801

Title: Photoactivation of corticosteroids in UVB-exposed skin.

Journal: Journal of photochemistry and photobiology. B, Biology 20110404

Title: Development and validation of a method for determination of corticosteroids in pig fat using liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110215

Title: Determination of dexamethasone and dexamethasone sodium phosphate in human plasma and cochlear perilymph by liquid chromatography/tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101

Title: Detection of stanozolol in environmental waters using liquid chromatography tandem mass spectrometry.

Journal: Chemistry Central journal 20110101

Title: Quantitative determination of corticosteroids in bovine milk using mixed-mode polymeric strong cation exchange solid-phase extraction and liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Quantification of corticosteroids in bovine urine using selective solid phase extraction and reversed-phase liquid chromatography/tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601

Title: Generic sample preparation combined with high-resolution liquid chromatography-time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories.

Journal: Analytical and bioanalytical chemistry 20100401

Title: Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish.

Journal: Journal of leukocyte biology 20100201

Title: Simultaneous determination of corticosteroids, androgens, and progesterone in river water by liquid chromatography-tandem mass spectrometry.

Journal: Chemosphere 20100201

Title: Screening and quantitative confirmatory method for the analysis of glucocorticoids in bovine milk using liquid chromatography-tandem mass spectrometry.

Journal: Journal of AOAC International 20100101

Title: Determination of anabolic steroids in muscle tissue by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: Development of a rapid method for the analysis of synthetic growth promoters in bovine muscle using liquid chromatography tandem mass spectrometry.

Journal: Analytica chimica acta 20090401

Title: A simple and rapid ESI-LC-MS/MS method for simultaneous screening of doping agents in urine samples.

Journal: Indian journal of pharmacology 20090401

Title: Lecithin based nanoemulsions: A comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation.

Journal: International journal of pharmaceutics 20090331

Title: Validation of a solid-phase extraction and ultra-performance liquid chromatographic tandem mass spectrometric method for the detection of 16 glucocorticoids in pig tissues.

Journal: Journal of AOAC International 20090101

Title: A liquid chromatography method using a monolithic column for the determination of corticoids in animal feed and animal feeding water.

Journal: Analytical and bioanalytical chemistry 20080801

Title: Optimization of solid phase extraction clean up and validation of quantitative determination of corticosteroids in urine by liquid chromatography-tandem mass spectrometry.

Journal: Analytica chimica acta 20080609

Title: Flexor carpi ulnaris tendonopathy in a Weimaraner.

Journal: Australian veterinary journal 20071001

Title: Rapid multi-residue method for the quantitative determination and confirmation of glucocorticosteroids in bovine milk using liquid chromatography-electrospray ionization-tandem mass spectrometry.

Journal: Analytica chimica acta 20070404

Title: Effect of selected fluorinated drugs in a 'ringing' gel on rheological behaviour and skin permeation.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401

Title: High throughput HPLC-ESI-MS method for the quantitation of dexamethasone in blood plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20070104

Title: Medical treatment of vulvar squamous cell hyperplasia.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20061201

Title: A chromatography method for the screening and confirmatory detection of dexamethasone.

Journal: Meat science 20061201

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Regression of subcorneal pustular dermatosis type of IgA pemphigus lesions with azithromycin.

Journal: The Journal of infection 20050801

Title: G-protein-coupled glucocorticoid receptors on the pituitary cell membrane.

Journal: Journal of cell science 20050801

Title: Confirmation of synthetic glucocorticoids with liquid chromatography/mass spectrometry: organization and results of an international interlaboratory comparison test.

Journal: Journal of AOAC International 20050101

Title: Detection of synthetic corticosteroids in bovine urine by chemiluminescence high-performance liquid chromatography.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: Effect of steroidal and non-steroidal anti-inflammatory drugs on inflammatory markers in calves with experimentally-induced bronchopneumonia.

Journal: Berliner und Munchener tierarztliche Wochenschrift 20050101

Title: Otic drops used to clear a blocked grommet: an in vitro prospective randomized controlled study with blinded assessment.

Journal: Clinical otolaryngology and allied sciences 20041201

Title: Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties.

Journal: European journal of endocrinology 20040901

Title: Development of a dual luciferase reporter screening assay for the detection of synthetic glucocorticoids in animal tissues.

Journal: The Analyst 20031201

Title: Effect of steroidal and non-steroidal anti-inflammatory drugs in combination with long-acting oxytetracycline on non-specific immunity of calves suffering from enzootic bronchopneumonia.

Journal: Veterinary microbiology 20031008

Title: Immunochemical screening and liquid chromatographic-tandem mass spectrometric confirmation of drug residues in edible tissues of calves injected with a therapeutic dose of the synthetic glucocorticoids dexamethasone and flumethasone.

Journal: Journal of agricultural and food chemistry 20030101

Title: A high-performance liquid chromatography/tandem mass spectrometric screening method for eight synthetic corticosteroids in bovine feces and the simultaneous differentiation between dexamethasone and betamethasone.

Journal: Rapid communications in mass spectrometry : RCM 20020101

Title: Determination of flumethasone in calf urine and serum by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: Accelerated solvent extraction and liquid chromatography-tandem mass spectrometry quantitation of corticosteroid residues in bovine liver.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010405

Title: Corticosteroid-induced cutaneous atrophy and telangiectasia. Experimental production associated with weight loss in rats.

Journal: Archives of dermatology 19760801

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Tags:2135-17-3 Molecular Formula|2135-17-3 MDL|2135-17-3 SMILES|2135-17-3 Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-