+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
2172651-73-7,MFCD31746888
Catalog No.:AA01FNN6

2172651-73-7 | RMC-4550

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$49.00   $34.00
- +
5mg
98+%
in stock  
$124.00   $87.00
- +
10mg
98+%
in stock  
$184.00   $129.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01FNN6
Chemical Name:
RMC-4550
CAS Number:
2172651-73-7
Molecular Formula:
C21H26Cl2N4O2
Molecular Weight:
437.3627
MDL Number:
MFCD31746888
SMILES:
OCc1nc(c(nc1N1CCC2(CC1)CO[C@H]([C@H]2N)C)C)c1cccc(c1Cl)Cl
Properties
Computed Properties
 
Complexity:
563  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.5  

Downstream Synthesis Route

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

[2]Chen,Xiao;Du,Guangying;Hu,Zhengping;Tian,Jingwei;Wang,Hongbo;Wang,Wenyan;Ye,Liang;Yu,Pengfei;Zou,Fangxia[ToxicologyandAppliedPharmacology,2020,vol.398]

1269026-22-3   
{3-(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro4.5decan-8-yl-6-(2,3-dichlorophenyl)-5-methylpyrazin-2-yl}methanol 

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1Locationinpatent:Paragraph0601

[2]Chen,Xiao;Du,Guangying;Hu,Zhengping;Tian,Jingwei;Wang,Hongbo;Wang,Wenyan;Ye,Liang;Yu,Pengfei;Zou,Fangxia[ToxicologyandAppliedPharmacology,2020,vol.398]

Literature

Title: Nichols RJ, et al. RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers. Nat Cell Biol. 2018 Sep;20(9):1064-1073.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 2172651-73-7
Building Blocks
More >
Historical Records
36943-39-2

36943-39-2

 902903-97-3

902903-97-3

 872689-26-4

872689-26-4
Tags:2172651-73-7 Molecular Formula|2172651-73-7 MDL|2172651-73-7 SMILES|2172651-73-7 RMC-4550
Catalog No.: AA01FNN6
2172651-73-7,MFCD31746888
2172651-73-7 | RMC-4550
Pack Size： 1mg
Purity： 98+%
in stock
$49.00 $34.00
Pack Size： 5mg
Purity： 98+%
in stock
$124.00 $87.00
Pack Size： 10mg
Purity： 98+%
in stock
$184.00 $129.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01FNN6
Chemical Name: RMC-4550
CAS Number: 2172651-73-7
Molecular Formula: C21H26Cl2N4O2
Molecular Weight: 437.3627
MDL Number: MFCD31746888
SMILES: OCc1nc(c(nc1N1CCC2(CC1)CO[C@H]([C@H]2N)C)C)c1cccc(c1Cl)Cl
Properties
Complexity: 563  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 29  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.5  
Downstream Synthesis Route
141872-22-2    2172651-73-7 

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

2091009-80-0    2172651-73-7 

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

[2]Chen,Xiao;Du,Guangying;Hu,Zhengping;Tian,Jingwei;Wang,Hongbo;Wang,Wenyan;Ye,Liang;Yu,Pengfei;Zou,Fangxia[ToxicologyandAppliedPharmacology,2020,vol.398]

1269026-22-3   
{3-(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro4.5decan-8-yl-6-(2,3-dichlorophenyl)-5-methylpyrazin-2-yl}methanol 

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

2172654-36-1    2172651-73-7 

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1

2172654-37-2    2172651-73-7 

[1]CurrentPatentAssignee:REVOLUTIONMEDICINESINC-WO2018/13597,2018,A1Locationinpatent:Paragraph0601

[2]Chen,Xiao;Du,Guangying;Hu,Zhengping;Tian,Jingwei;Wang,Hongbo;Wang,Wenyan;Ye,Liang;Yu,Pengfei;Zou,Fangxia[ToxicologyandAppliedPharmacology,2020,vol.398]

Related Products of of 2172651-73-7
Building Blocks More >
1172134-11-0
1172134-11-0
Spirotetramat-keto-hydroxy
AA01FNX2
1219803-65-2
1219803-65-2
(+/-)-3-Amino-iso-butyric-2,3,3-d3 Acid (racemic)
AA01FO0U
883510-80-3
883510-80-3
4-[(4-Benzylphenoxy)methyl]piperidine
AA01FO3J
946741-55-5
946741-55-5
4-(3-Pyridinyloxy)-2-(trifluoromethyl)aniline
AA01FO6E
940519-83-5
940519-83-5
4-{4-[(sec-Butylamino)carbonyl]anilino}-4-oxobutanoic acid
AA01FO97
1185301-80-7
1185301-80-7
Methyl-(7-methyl-2-pyrrolidin-3-yl-5,6,7,8-tetrahydro-pyrido[3
AA01FOBK
19621-28-4
19621-28-4
3-[2-(Tritylamino)ethyl]-1H-indol-5-ol
AA01FOEC
601516-17-0
601516-17-0
tert-Butyl 2-formyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate
AA01FOI6 | MFCD12755222
1538566-78-7
1538566-78-7
6,7-bis(3-methoxyphenyl)-2-sulfanylpteridin-4-ol
AA01FOLF
321385-57-3
321385-57-3
ethyl 2-{[2-(1H-indol-3-ylmethylene)hydrazino]carbonyl}-3-{[3-(trifluoromethyl)anilino]carbonyl}cyclopropanecarboxylate
AA01FONY
Historical Records
36943-39-2
36943-39-2
902903-97-3
902903-97-3
872689-26-4
872689-26-4
Submit
© 2017 AA BLOCKS, INC. All rights reserved.