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Journal: Journal of clinical laboratory analysis 20120501
Title: Antigenotoxic effect of the Plumbago zeylanica extract against the genotoxic damage induced by potassium canrenoate in cultured human peripheral blood lymphocytes.
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Title: Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
Journal: American journal of physiology. Heart and circulatory physiology 20120301
Title: Activation of the mineralocorticoid receptor increases striatin levels.
Journal: American journal of hypertension 20120201
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Title: Differential effects of mineralocorticoid blockade on the hypothalamo-pituitary-adrenal axis in pregnant and nonpregnant ewes.
Journal: American journal of physiology. Endocrinology and metabolism 20110301
Title: Abbott ARCHITECT clinical chemistry and immunoassay systems: digoxin assays are free of interferences from spironolactone, potassium canrenoate, and their common metabolite canrenone.
Journal: Therapeutic drug monitoring 20110201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
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Title: Spironolactone and canrenone inhibit UGT2B7-catalyzed human liver and kidney microsomal aldosterone 18beta-glucuronidation: a potential drug interaction.
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Title: Effect of acute and prolonged mineralocorticoid receptor blockade on spontaneous and stimulated hypothalamic-pituitary-adrenal axis in humans.
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Title: Amiloride reduces portal hypertension in rat liver cirrhosis.
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Title: Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis: results of an open randomised clinical trial.
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Title: Effect of spironolactone, potassium canrenoate, and their common metabolite canrenone on Dimension Vista Digoxin Assay.
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Title: Effect of spironolactone, potassium canrenoate and their common metabolite canrenone on serum digoxin measurement by digoxin III, a new digoxin immunoassay.
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Title: Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients.
Journal: American journal of hypertension 20080901
Title: Cardiac corticosteroid receptors mediate the enlargement of the ovine fetal heart induced by chronic increases in maternal cortisol.
Journal: The Journal of endocrinology 20080801
Title: Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor.
Journal: American journal of physiology. Endocrinology and metabolism 20080601
Title: Time-course reduction of renal function in rats on high sodium intake: acute reversal by potassium canrenoate.
Journal: Clinical and experimental pharmacology & physiology 20080401
Title: Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats: discordant enantioselectivity versus reduction of plasma aldosterone.
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Title: Spontaneous resolution of idiopathic aldosteronism after long-term treatment with potassium canrenoate.
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Title: Renal sodium retention in cirrhotic rats depends on glucocorticoid-mediated activation of mineralocorticoid receptor due to decreased renal 11beta-HSD-2 activity.
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Title: Primary hyperaldosteronism is associated with derangement in the regulation of the hypothalamus-pituitary-adrenal axis in humans.
Journal: Journal of endocrinological investigation 20070101
Title: Effect of potassium canrenoate, an anti-aldosterone agent, on incidence of ascites and variceal progression in cirrhosis.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Effects of canrenoate plus angiotensin-converting enzyme inhibitors versus angiotensin-converting enzyme inhibitors alone on systolic and diastolic function in patients with acute anterior myocardial infarction.
Journal: American heart journal 20051101
Title: Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade.
Journal: The Journal of clinical endocrinology and metabolism 20051001
Title: Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channels.
Journal: British journal of pharmacology 20050901
Title: Cardiac, neuroadrenergic, and portal hemodynamic effects of prolonged aldosterone blockade in postviral child A cirrhosis.
Journal: The American journal of gastroenterology 20050501
Title: Aldosterone blunts human baroreflex sensitivity by a nongenomic mechanism.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050501
Title: Idiopathic primary hyperaldosteronism: normalization of plasma aldosterone after one month withdrawal of long-term therapy with aldosterone-receptor antagonist potassium canrenoate.
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Title: Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist.
Journal: Journal of cardiovascular pharmacology 20050101
Title: Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model.
Journal: Journal of pharmacological sciences 20041201
Title: Elevated resting and exercise-induced cortisol levels after mineralocorticoid receptor blockade with canrenoate in healthy humans.
Journal: The Journal of clinical endocrinology and metabolism 20041001
Title: Effects of the aldosterone receptor antagonist potassium canrenoate on renal blood flow and urinary output during prolonged increased intraabdominal pressure (IAP) in pigs.
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Title: Potassium canrenoate, an aldosterone receptor antagonist, reduces isoprenaline-induced cardiac fibrosis in the rat.
Journal: The Journal of pharmacology and experimental therapeutics 20040601
Title: Acute aldosterone antagonism improves cardiac vagal control in humans.
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Title: A new turbidometric digoxin immunoassay on the ADVIA 1650 analyzer is free from interference by spironolactone, potassium canrenoate, and their common metabolite canrenone.
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Title: Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels.
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Title: The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans.
Journal: The Journal of clinical endocrinology and metabolism 20021001
Title: DNA damage in tissues of rat treated with potassium canrenoate.
Journal: Toxicology 20020227
Title: Bidirectional (positive/negative) interference of spironolactone, canrenone, and potassium canrenoate on serum digoxin measurement: elimination of interference by measuring free digoxin or using a chemiluminescent assay for digoxin.
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Title: Mineralocorticoid receptor blockade by canrenoate increases both spontaneous and stimulated adrenal function in humans.
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Title: Aldosterone and myocardial infarction--are aldosterone antagonists needed to prevent remodelling or does ACE inhibition suffice?
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Title: ACE-inhibition plus mineralocorticoid antagonism versus ACE-inhibition alone in patients with anterior myocardial infarction.
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Title: Collecting duct is a site of sodium retention in PAN nephrosis: a rationale for amiloride therapy.
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Title: The combination ace-inhibitors plus canreonate in patients with anterior myocardial infarction: safety and tolerability study.
Journal: International journal of cardiology 20010201
Title: Additional beneficial effects of canrenoate in patients with anterior myocardial infarction on ACE-inhibitor treatment. A pilot study.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20010201
Title: Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction.
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