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2192-20-3,MFCD00058200
Catalog No.:AA00I46L

2192-20-3 | Hydroxyzine dihydrochloride

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1g
98%(HPLC)
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$24.00   $17.00
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5g
97%
in stock  
$62.00   $44.00
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25g
97%
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$170.00   $119.00
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100g
97%
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$502.00   $352.00
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500g
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$1,640.00   $1,148.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I46L
Chemical Name:
Hydroxyzine dihydrochloride
CAS Number:
2192-20-3
Molecular Formula:
C21H29Cl3N2O2
Molecular Weight:
447.8262
MDL Number:
MFCD00058200
SMILES:
OCCOCCN1CCN(CC1)C(c1ccc(cc1)Cl)c1ccccc1.Cl.Cl
Properties
Properties
 
BP:
499.2°C at 760 mmHg  
Form:
Solid  
MP:
190-192°C  
Solubility:
H2O: soluble  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
376  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Selective inhibition of hepatitis C virus infection by hydroxyzine and benztropine.

Journal: Antimicrobial agents and chemotherapy 20140601

Title: Understanding the pharmacokinetics of anxiolytic drugs.

Journal: Expert opinion on drug metabolism & toxicology 20130401

Title: Two-step liquid phase microextraction combined with capillary electrophoresis: a new approach to simultaneous determination of basic and zwitterionic compounds.

Journal: Journal of separation science 20120801

Title: Non-opioid drugs for pain management in labour.

Journal: The Cochrane database of systematic reviews 20120711

Title: Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant.

Journal: Environmental science and pollution research international 20120601

Title: Dexmedetomidine and hydroxyzine synergistically potentiate the hypnotic activity of propofol in mice.

Journal: Journal of anesthesia 20120601

Title: LSD screening in urine performed by CEDIA® LSD assay: positive interference with sertraline.

Journal: Journal of analytical toxicology 20120501

Title: Sedation of children undergoing dental treatment.

Journal: The Cochrane database of systematic reviews 20120314

Title: Double-blind placebo-controlled evaluation of the PROMETA™ protocol for methamphetamine dependence.

Journal: Addiction (Abingdon, England) 20120201

Title: Treatment strategies of obsessive-compulsive disorder and panic disorder/agoraphobia.

Journal: Current topics in medicinal chemistry 20120101

Title: Hydroxyzine, cimetidine and vitamin C in reducing skin flap necrosis in ischemia-reperfusion injury in rats. A comparative study.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20120101

Title: Acute and subchronic effects of bilastine (20 and 40 mg) and hydroxyzine (50 mg) on actual driving performance in healthy volunteers.

Journal: Journal of psychopharmacology (Oxford, England) 20111101

Title: [Bradykinin-mediated angioedema secondary to angiotensin converting enzyme: initiate treatment from the prehospital phase].

Journal: Annales francaises d'anesthesie et de reanimation 20111101

Title: Nodular scabies: hypersensitivity reaction or infection?

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20111001

Title: In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery.

Journal: AAPS PharmSciTech 20110901

Title: Effects of hydroxyzine-midazolam premedication on sevoflurane-induced paediatric emergence agitation: a prospective randomised clinical trial.

Journal: European journal of anaesthesiology 20110901

Title: A fatality due to an accidental methadone substitution in a dental cocktail.

Journal: Journal of analytical toxicology 20110901

Title: Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration.

Journal: Acta pharmacologica Sinica 20110901

Title: Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis.

Journal: Experimental dermatology 20110701

Title: Short-term effects of morning versus evening dose of hydroxyzine 50 mg on cognition in healthy volunteers.

Journal: Journal of clinical psychopharmacology 20110601

Title: Sorption of emerging trace organic compounds onto wastewater sludge solids.

Journal: Water research 20110501

Title: Chiral separation and quantitation of cetirizine and hydroxyzine by maltodextrin-mediated CE in human plasma: effect of zwitterionic property of cetirizine on enantioseparation.

Journal: Electrophoresis 20110301

Title: Annular groin eruptions: pityriasis rosea of vidal.

Journal: International journal of dermatology 20110201

Title: Primary dermatologic findings with early-onset intrahepatic cholestasis of pregnancy.

Journal: Obstetrics and gynecology 20110201

Title: Bispectral index monitoring of sedation depth in pediatric dental patients.

Journal: Anesthesia progress 20110101

Title: Generalised anxiety disorder.

Journal: BMJ clinical evidence 20110101

Title: Hydroxyzine for generalised anxiety disorder.

Journal: The Cochrane database of systematic reviews 20101208

Title: The importance of taking a history of over-the-counter medication use: a brief review and case illustration of 'PRN' antihistamine dependence in a hospitalized adolescent.

Journal: Journal of child and adolescent psychopharmacology 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Prevention of nausea and vomiting during termination of pregnancy.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20101001

Title: Delayed recrudescence to toxic salicylate concentrations after salsalate overdose.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100601

Title: The effects of single dose anxiolytic medication on the CO2 models of anxiety: differentiation of subjective and objective measures.

Journal: Journal of psychopharmacology (Oxford, England) 20100501

Title: Moderate sedation for echocardiography of preschoolers.

Journal: Pediatric cardiology 20100501

Title: Hydroxyzine hydrochloride in familial restless legs syndrome.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100501

Title: Clinical reasoning: seizures in a child with sensorineural deafness and agitation.

Journal: Neurology 20100413

Title: Effectiveness of premedication agents administered prior to nitrous oxide/oxygen.

Journal: European journal of anaesthesiology 20100401

Title: Chorea induced by antihistamine drugs.

Journal: Movement disorders : official journal of the Movement Disorder Society 20100315

Title: [Skin rash on an infant].

Journal: Actas dermo-sifiliograficas 20100301

Title: Hydroxyzine and cetirizine interfere with the PENTINA carbamazepine assay but not with the ADVIA CENTEUR carbamazepine assay.

Journal: Therapeutic drug monitoring 20100201

Title: Dapsone hypersensitivity syndrome during delayed pressure urticaria treatment.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20100201

Title: Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.

Journal: International archives of allergy and immunology 20100101

Title: Comparative evaluation of antipruritic protocols in acute burns. The emerging value of gabapentin in the treatment of burns pruritus.

Journal: Journal of burn care & research : official publication of the American Burn Association 20100101

Title: Papuloerythroderma 2009: two new cases and systematic review of the worldwide literature 25 years after its identification by Ofuji et al.

Journal: Dermatology (Basel, Switzerland) 20100101

Title: [Comparative characteristics of hydroxyzine (atarax) and diazepam in the premedication regimen in children in dental practice].

Journal: Anesteziologiia i reanimatologiia 20100101

Title: Analytical performance evaluation of ADVIA Chemistry Carbamazepine_2 assay: minimal cross-reactivity with carbamazepine 10, 11-epoxide and none with hydroxyzine or cetirizine.

Journal: Journal of clinical laboratory analysis 20100101

Title: Dose dependency of brain histamine H(1) receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with [11C]doxepin.

Journal: Human psychopharmacology 20091001

Title: Effects of dexamethasone and hydroxyzine treatment on intradermal testing and allergen-specific IgE serum testing results in horses.

Journal: Veterinary dermatology 20091001

Title: Anaphylactic reaction to hydroxyzine in an anesthetized patient.

Journal: European annals of allergy and clinical immunology 20090801

Title: Triprotic acid-base microequilibria and pharmacokinetic sequelae of cetirizine.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

Title: Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090601

Title: What the first 10,000 patients with chronic urticaria have taught me: a personal journey.

Journal: The Journal of allergy and clinical immunology 20090301

Title: Efficacy of leukotriene receptor antagonist with an anti-H1 receptor antagonist for treatment of chronic idiopathic urticaria.

Journal: The Journal of dermatological treatment 20090101

Title: Metoprolol succinate therapy associated with erythema multiforme.

Journal: Cardiology journal 20090101

Title: Interstitial cystitis.

Journal: Medicine and health, Rhode Island 20090101

Title: Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.

Journal: Drugs 20090101

Title: Experience with cyclosporine in children with chronic idiopathic urticaria.

Journal: Pediatric dermatology 20090101

Title: Multimodal therapy for painful bladder syndrome / interstitial cystitis: pilot study combining behavioral, pharmacologic, and endoscopic therapies.

Journal: International braz j urol : official journal of the Brazilian Society of Urology 20090101

Title: Stevens-Johnson syndrome: a case report.

Journal: Allergologia et immunopathologia 20090101

Title: Effect on behavior of dental treatment rendered under conscious sedation and general anesthesia in pediatric patients.

Journal: Pediatric dentistry 20090101

Title: Hydroxyzine and cetirizine pharmacokinetics and pharmacodynamics after oral and intravenous administration of hydroxyzine to healthy dogs.

Journal: Veterinary dermatology 20081201

Title: Comparison of peripheral and central effects of single and repeated oral dose administrations of bilastine, a new H1 antihistamine: a dose-range study in healthy volunteers with hydroxyzine and placebo as control treatments.

Journal: Journal of clinical psychopharmacology 20081201

Title: Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation.

Journal: Journal of pharmacological sciences 20081201

Title: Anticholinergic esotropia.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20081201

Title: Conscious sedation in the critically ill ventilated patient.

Journal: Journal of critical care 20080901

Title: Treatment of chronic autoimmune urticaria with omalizumab.

Journal: The Journal of allergy and clinical immunology 20080901

Title: Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis.

Journal: American journal of obstetrics and gynecology 20080701

Title: [The complexity of chronic pelvic pain exemplified by the condition currently called interstitial cystitis. Part 2: Treatment].

Journal: Aktuelle Urologie 20080701

Title: Molecularly imprinted polymer based potentiometric sensor for the determination of hydroxyzine in tablets and biological fluids.

Journal: Analytica chimica acta 20080331

Title: Knowledge of pharmacists regarding ritalin and ADHD and their attitude towards the use of ritalin to treat ADHD.

Journal: International journal of clinical pharmacology and therapeutics 20080201

Title: Development of a voltammetric procedure for assay of the antihistamine drug hydroxyzine at a glassy carbon electrode: Quantification and pharmacokinetic studies.

Journal: Talanta 20080115

Title: Exudative erythema multiforme induced by hydroxyzine.

Journal: European journal of dermatology : EJD 20080101

Title: Physicochemical, pharmacological and pharmacokinetic properties of the zwitterionic antihistamines cetirizine and levocetirizine.

Journal: Current medicinal chemistry 20080101

Title: Concurrent use of anticholinergic drugs and cholinesterase inhibitors: register-based study of over 700,000 elderly patients.

Journal: Drugs & aging 20080101

Title: Perioperative management of obstructive sleep apnea with nasal continuous positive airway pressure.

Journal: Anesthesia progress 20080101

Title: [Pruritic urticarial papules and plaques of pregnancy].

Journal: Akusherstvo i ginekologiia 20080101

Title: Worsening of atopic dermatitis by hazelnut essence contained in hydroxyzine syrup.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20071101

Title: Unusual adulterants in cocaine seized on Italian clandestine market.

Journal: Forensic science international 20071025

Title: Precolumn fluorescence labeling method for simultaneous determination of hydroxyzine and cetirizine in human serum.

Journal: Biomedical chromatography : BMC 20071001

Title: Open-label study of a proprietary treatment program targeting type A gamma-aminobutyric acid receptor dysregulation in methamphetamine dependence.

Journal: Mayo Clinic proceedings 20071001

Title: Evaluation of enantioselective binding of antihistamines to human serum albumin by ACE.

Journal: Electrophoresis 20070801

Title: Depressive symptoms in urticaria patients treated with first- or second-generation histamine 1 receptor antagonists.

Journal: Journal of clinical psychopharmacology 20070801

Title: A case of urticaria induced by both hydroxyzine and cetirizine but not by levocetirizine.

Journal: Allergy 20070701

Title: Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers.

Journal: Human psychopharmacology 20070701

Title: Interstitial cystitis/painful bladder syndrome.

Journal: Urologic nursing 20070601

Title: The experience of childbrith in first-time mothers who received narcotic analgesics during the first stage of labour.

Journal: Curationis 20070601

Title: Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial.

Journal: The American journal of gastroenterology 20070401

Title: Rational approaches to the treatment of patients with interstitial cystitis.

Journal: Urology 20070401

Title: Acute episode or chronic problem?

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20070401

Title: Sulpiride plus hydroxyzine decrease tinnitus perception.

Journal: Auris, nasus, larynx 20070301

Title: [Hydroxyzine premedication does not alter bispectral index changes following etomidate induction of general anaesthesia].

Journal: Annales francaises d'anesthesie et de reanimation 20070301

Title: False-positive serum tricyclic antidepressant concentrations using fluorescence polarization immunoassay due to the presence of hydroxyzine and cetirizine.

Journal: Therapeutic drug monitoring 20070201

Title: Comparison of hydroxyzine and doxepin in treatment of pruritus due to sulfur mustard.

Journal: Skinmed 20070101

Title: Turbidimetric carbamazepine immunoassay on the ADVIA 1650 and 2400 analyzers is free from interference of antihistamine drugs hydroxyzine and cetirizine.

Journal: Journal of clinical laboratory analysis 20070101

Title: The painful bladder: urinary tract infection and interstitial cystitis in women.

Journal: Missouri medicine 20070101

Title: Comparison of three conscious sedation regimens for pediatric dental patients.

Journal: The Journal of clinical pediatric dentistry 20070101

Title: Cetirizine, doxepine, and hydroxyzine in the treatment of pruritus due to sulfur mustard: a randomized clinical trial.

Journal: Cutaneous and ocular toxicology 20070101

Title: Study of the EEG changes during the combined ingestion of alcohol and H1-antihistamines by using the wavelet transform.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20070101

Title: A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation.

Journal: Brazilian dental journal 20070101

Title: [Use of anxiolytic atarax as a substitutive drug for benzodiazepine tranquilizers].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

Title: [The use of atarax in the treatment of attention deficit syndrome with hyperactivity and anxiety].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

Title: Interdisciplinary approach to endodontic therapy for uncooperative children in a dental school environment.

Journal: Journal of dental education 20061201

Title: Trichotillomania: a treatment overview.

Journal: The Journal of practical nursing 20061201

Title: False-positive serum tricyclic antidepressant concentrations using fluorescence polarization immunoassay due to the presence of hydroxyzine and cetirizine.

Journal: Therapeutic drug monitoring 20061001

Title: Skin tears?

Journal: The American journal of medicine 20060801

Title: Severe cholinergic urticaria successfully treated with scopolamine butylbromide in addition to antihistamines.

Journal: Clinical and experimental dermatology 20060701

Title: Skin reaction to hydroxyzine (Atarax): patch test utility.

Journal: Contact dermatitis 20060401

Title: Mucosal eosinophilia and response to H1/H2 antagonist and cromolyn therapy in pediatric dyspepsia.

Journal: Clinical pediatrics 20060301

Title: Hydroxyzine, promethazine and thioridazine interaction with phospholipid monomolecular layers at the air-water interface.

Journal: Biophysical chemistry 20060201

Title: Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers.

Journal: Human psychopharmacology 20060101

Title: [A case of drug eruption induced by hydroxyzine pamoate].

Journal: Arerugi = [Allergy] 20060101

Title: Children sedated for dental care: a pilot study of the 24-hour postsedation period.

Journal: Pediatric dentistry 20060101

Title: Assessment of the effects of 2 sedation regimens on cardiopulmonary parameters in pediatric dental patients: a retrospective study.

Journal: Pediatric dentistry 20060101

Title: Survey of sedation techniques used Among pediatric dentists in New York State.

Journal: The New York state dental journal 20060101

Title: [The use of atarax in the treatment of tic hyperkinesia in children: a pilot study].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

Title: A prospective study of 2 sedation regimens in children: chloral hydrate, meperidine, and hydroxyzine versus midazolam, meperidine, and hydroxyzine.

Journal: Anesthesia progress 20060101

Title: Inhibition of amine oxidases by the histamine-1 receptor antagonist hydroxyzine.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Patient response in a screened population for interstitial cystitis.

Journal: Comprehensive therapy 20060101

Title: Generalised anxiety disorder.

Journal: Clinical evidence 20051201

Title: Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use.

Journal: Human psychopharmacology 20051001

Title: Transport of hydroxyzine and triprolidine across bovine olfactory mucosa: role of passive diffusion in the direct nose-to-brain uptake of small molecules.

Journal: International journal of pharmaceutics 20050930

Title: Bradycardia and hypertension in anticipation of, and exacerbated by, peribulbar block: a prospective audit.

Journal: Acta anaesthesiologica Scandinavica 20050901

Title: Tracheal intubation in routine practice with and without muscular relaxation: an observational study.

Journal: European journal of anaesthesiology 20050901

Title: Effect of (+) or (-) camphorsulfonic acid additives to the mobile phase on enantioseparations of some basic drugs on a Chiralcel OD column.

Journal: Journal of chromatography. A 20050812

Title: Hydroxyzine and metabolites as a source of interference in carbamazepine particle-enhanced turbidimetric inhibition immunoassay (PETINIA).

Journal: Therapeutic drug monitoring 20050801

Title: Interstitial cystitis: a primary care perspective.

Journal: Cleveland Clinic journal of medicine 20050801

Title: Effects of calcineurin inhibitors on an in vitro assay for chronic urticaria.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050501

Title: Perioral angioedema associated with angiotensin-converting enzyme inhibitor.

Journal: Journal of periodontology 20050401

Title: Sedation in the critically ill ventilated patient: possible role of enteral drugs.

Journal: Intensive care medicine 20050301

Title: Hydroxyzine- and cetirizine-loaded liposomes: effect of duration of thin film hydration, freeze-thawing, and changing buffer pH on encapsulation and stability.

Journal: Drug development and industrial pharmacy 20050301

Title: [Methadone and sleep apnea syndrome].

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20050301

Title: Observations of the 'carry-over effect' following successful termination of chronic migraine in the adolescent with short-term dihydroergotamine, dexamethasone and hydroxyzine: a pilot study.

Journal: The journal of headache and pain 20050201

Title: [A case of catatonia associated with the ingestion of hydroxyzine].

Journal: No to shinkei = Brain and nerve 20050101

Title: [Therapeutic options in idiopathic chronic urticaria].

Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20050101

Title: Comparison of chloral hydrate, meperidine, and hydroxyzine to midazolam regimens for oral sedation of pediatric dental patients.

Journal: Pediatric dentistry 20050101

Title: [A comparative study of the effect of brazidole, amiodarone, sotalol, and hydroxyzine on potassium ionic channels of mollusks neurons].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20050101

Title: Neonatal seizures associated with maternal hydroxyzine hydrochloride in late pregnancy.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: A pilot, open label, clinical trial using hydroxyzine in multiple sclerosis.

Journal: International journal of immunopathology and pharmacology 20050101

Title: Pityriasis rosea-like eruptions due to mustard oil application.

Journal: Indian journal of dermatology, venereology and leprology 20050101

Title: Generalised anxiety disorder.

Journal: Clinical evidence 20041201

Title: Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip.

Journal: Pharmacology, biochemistry, and behavior 20040901

Title: Ropivacaine-induced asystole: 'never again' rather than 'here we go again'.

Journal: Anesthesiology 20040801

Title: Cutaneous drug eruption from cetirizine and hydroxyzine.

Journal: Journal of the American Academy of Dermatology 20040601

Title: Premedications and peribulbar analgesia--a prospective audit.

Journal: Middle East journal of anaesthesiology 20040601

Title: Generalised anxiety disorder.

Journal: Clinical evidence 20040601

Title: Hydroxyzine-induced supraventricular tachycardia in a nine-year-old child.

Journal: Singapore medical journal 20040201

Title: [Drugs for the treatment of Alzheimer's disease].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040101

Title: A simple high-performance liquid chromatographic method for detection of hydroxyzine in human plasma after overdose.

Journal: Journal of pharmacological and toxicological methods 20040101

Title: Aquagenic urticaria: report of a case.

Journal: Allergy and asthma proceedings 20040101

Title: Selecting pharmacotherapy for generalized anxiety disorder.

Journal: The Journal of clinical psychiatry 20040101

Title: [Inflammatory mediators in patients with atopic dermatitis after treatment with transfer factor].

Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

Title: Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers.

Journal: Neuropsychobiology 20040101

Title: Comparison of oral midazolam with and without hydroxyzine in the sedation of pediatric dental patients.

Journal: Pediatric dentistry 20040101

Title: [Autoimmune urticaria. Treatment with methotrexate].

Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

Title: Psychogenic intractable sneezing: case reports and a review of treatment options.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031201

Title: Hydroxyzine from topical phospholipid liposomal formulations: evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model.

Journal: AAPS pharmSci 20031201

Title: P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine.

Journal: Journal of pharmaceutical sciences 20031001

Title: A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis.

Journal: The Journal of urology 20030901

Title: Quantitative enantiomeric analysis of chlorcyclizine, hydroxyzine, and meclizine by capillary electrophoresis.

Journal: Analytical and bioanalytical chemistry 20030701

Title: Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense.

Journal: The Korean journal of parasitology 20030601

Title: Generalised anxiety disorder.

Journal: Clinical evidence 20030601

Title: A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car.

Journal: Clinical therapeutics 20030501

Title: Treating generalised anxiety disorder.

Journal: BMJ (Clinical research ed.) 20030329

Title: Anxiolysis in general dental practice.

Journal: Dentistry today 20030301

Title: Hydroxyzine for generalized anxiety disorder.

Journal: The Journal of clinical psychiatry 20030301

Title: Beef allergy: a review of 12 cases.

Journal: Allergy 20030201

Title: A randomized, controlled, crossover trial of oral midazolam and hydroxyzine for pediatric dental sedation.

Journal: Pesquisa odontologica brasileira = Brazilian oral research 20030101

Title: Antibiotic-associated maculopapular reaction.

Journal: The Annals of pharmacotherapy 20021201

Title: Chronic urticaria and angioedema.

Journal: The New England journal of medicine 20021121

Title: Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study.

Journal: The Journal of clinical psychiatry 20021101

Title: [Cutaneous drug eruption with two antihistaminic drugs of a same chemical family: cetirizine and hydroxyzine].

Journal: Annales de dermatologie et de venereologie 20021101

Title: Premedication from a patient perspective--morphine, midazolam, hydroxyzine and placebo compared.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020901

Title: Immediate hypersensitivity reaction associated with the rapid infusion of Crotalidae polyvalent immune Fab (ovine).

Journal: Annals of emergency medicine 20020601

Title: Gabapentin in complicated school refusal.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 20020601

Title: Coma and apnea in a dog with hydroxyzine toxicosis.

Journal: Veterinary and human toxicology 20020201

Title: Titrimetric and spectrophotometric assay of some antihistamines through the determination of the chloride of their hydrochlorides.

Journal: Farmaco (Societa chimica italiana : 1989) 20020101

Title: Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).

Journal: Veterinary therapeutics : research in applied veterinary medicine 20020101

Title: Association between bispectral analysis and level of conscious sedation of pediatric dental patients.

Journal: Pediatric dentistry 20020101

Title: Project USAP 2000--use of sedative agents by pediatric dentists: a 15-year follow-up survey.

Journal: Pediatric dentistry 20020101

Title: [Carotid endarterectomy under remifentanil].

Journal: Revista espanola de anestesiologia y reanimacion 20011201

Title: Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs).

Journal: Biochemical pharmacology 20011101

Title: Adverse events and outcomes of conscious sedation for pediatric patients: study of an oral sedation regimen.

Journal: Journal of the American Dental Association (1939) 20011101

Title: Three cases of penile edema in peripubescent males.

Journal: Clinical pediatrics 20010901

Title: Treatment-resistant atopic dermatitis.

Journal: Journal of the American Geriatrics Society 20010701

Title: Lipophilicity behaviour of the Zwitterionic antihistamine cetirizine in phosphatidylcholine liposomes/water systems.

Journal: Pharmaceutical research 20010501

Title: [Dyshidrosis and acral purpura during polymorphic dermatitis in pregnancy: 2 cases].

Journal: Annales de dermatologie et de venereologie 20010401

Title: Effect of hydroxyzine on the transport of etoposide in rat small intestine.

Journal: Anti-cancer drugs 20010301

Title: Comparison of the effects of clonidine and hydroxyzine on haemodynamic and catecholamine reactions to microlaryngoscopy.

Journal: European journal of anaesthesiology 20010201

Title: Pharmacotherapy of generalized anxiety disorder.

Journal: The Journal of clinical psychiatry 20010101

Title: Pruritus.

Journal: Advances in dermatology 20010101

Title: Pharmacological blockade of ERG K(+) channels and Ca(2+) influx through store-operated channels exerts opposite effects on intracellular Ca(2+) oscillations in pituitary GH(3) cells.

Journal: Molecular pharmacology 20001101

Title: Hydroxyzine inhibits neurogenic bladder mast cell activation.

Journal: International journal of immunopharmacology 19981001

Title: [Benzodiazepine withdrawal presenting as pseudo-surgical abdominal pain].

Journal: Annales francaises d'anesthesie et de reanimation 19970101

Title: Intranasal midazolam better at effecting amnesia after sedation than oral hydroxyzine: a pilot study.

Journal: Pediatric dentistry 19960101

Title: Inhibition of mediator release in RBL-2H3 cells by some H1-antagonist derived anti-allergic drugs: relation to lipophilicity and membrane effects.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 19950201

Title: [Modification of cognitive functions by 2 anxiolytic treatments in patients suffering from generalized anxiety].

Journal: L'Encephale 19950101

Title: Prolonged penile erections induced by hydroxyzine: possible mechanism of action.

Journal: Neuropsychobiology 19940101

Title: Controlled trial of H1 antagonists in the treatment of chronic idiopathic urticaria.

Journal: Annals of allergy 19911001

Title: Direct measurement of daytime sleepiness after administration of cetirizine and hydroxyzine with a standardized electroencephalographic assessment.

Journal: The Journal of allergy and clinical immunology 19901201

Title: Cetirizine vs astemizole in the treatment of chronic idiopathic urticaria.

Journal: The Journal of international medical research 19900101

Title: Akathisia associated with droperidol during epidural anesthesia.

Journal: Anesthesiology 19891101

Title: Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine.

Journal: The Journal of allergy and clinical immunology 19890901

Title: A comparison of acrivastine versus hydroxyzine and placebo in the treatment of chronic idiopathic urticaria.

Journal: The Journal of international medical research 19890101

Title: Absence of amnesia induction in mice with hydroxyzine in comparison with three other minor tranquillizers.

Journal: Arzneimittel-Forschung 19880401

Title: Peripheral antihistamine and central sedative effects of three H1-receptor antagonists.

Journal: European journal of clinical pharmacology 19850101

Title: Opioid drugs cause bile duct obstruction during hepatobiliary scans.

Journal: American journal of surgery 19840101

Title: Comparative study of midazolam and vesparax in moderate or severe insomnia in female surgical patients.

Journal: British journal of clinical pharmacology 19830101

Title: Efficacy and safety of midazolam and vesparax in treatment of sleep disorders.

Journal: British journal of clinical pharmacology 19830101

Title: Hydroxyzine-associated tardive dyskinesia.

Journal: Annals of neurology 19820401

Title: Hydroxyzine hydrochloride: possible adverse cardiac interactions.

Journal: Psychopharmacology communications 19750101

Title: Effects of dextroamphetamine, chlorpromazine, and hydroxyzine on behavior and performance in hyperactive children.

Journal: The American journal of psychiatry 19721101

Title: [Intraspecific aggressive behavior induced by apomorphine in the rat].

Journal: Psychopharmacologia 19700101

Title: Circulatory and respiratory effects of hydroxyzine in volunteers and geriatric patients.

Journal: Anesthesia and analgesia 19680101

Title: The effect of SA 97, perphenazine, and hydroxyzine on epinephrine-induced cardiac arrhythmias during methoxyflurane anaesthesia in dogs.

Journal: Canadian Anaesthetists' Society journal 19620101

Title: Management of emotional disturbances; use of hydroxyzine (atarax) in general practice.

Journal: California medicine 19580601

Title: Cardiovascular action of hydroxyzine (atarax).

Journal: The Journal of pharmacology and experimental therapeutics 19561201

Title: Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63.

Title: Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979. 7(2): p. 173-80.

Title: Nikita Shekhar Sawantdesai, et al. Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice. J Basic Clin Pharm. 2016 Sep;7(4):97-104.

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Tags:2192-20-3 Molecular Formula|2192-20-3 MDL|2192-20-3 SMILES|2192-20-3 Hydroxyzine dihydrochloride