Name: Name:4-Hydroxyquinoline-6-carbonitrile
Brand: AABLOCKS
SKU: AA007OGX
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA007OGX

Chemical Name: 4-Hydroxyquinoline-6-carbonitrile

CAS Number: 219763-82-3

Molecular Formula: C10H6N2O

Molecular Weight: 170.1674

MDL Number: MFCD08063203

SMILES: N#Cc1ccc2c(c1)c(O)ccn2

Properties

Complexity: 299

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 13

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0.3

Downstream Synthesis Route

219763-82-3

219763-83-4

[1]CurrentPatentAssignee:NIMBUSTHERAPEUTICSINC-WO2015/164374,2015,A1Locationinpatent:Paragraph00409;00413

[2]CurrentPatentAssignee:UNIVERSITYOFSOUTHCAROLINA-US2020/62728,2020,A1Locationinpatent:Paragraph0108;0117-0118

[3]Zhang,Li;Cheng,Chen;Li,Jing;Wang,Lili;Chumanevich,AlexanderA.;Porter,DonaldC.;Mindich,Aleksei;Gorbunova,Svetlana;Roninson,IgorB.;Chen,Mengqian;McInnes,Campbell[JournalofMedicinalChemistry,2022,vol.65,#4,p.3420-3433]

[4]Madrid,PeterB.;Sherrill,John;Liou,AllyP.;Weisman,JenniferL.;DeRisi,JosephL.;Guy,R.Kiplin[BioorganicandMedicinalChemistryLetters,2005,vol.15,#4,p.1015-1018]

[5]CurrentPatentAssignee:ASTELLASPHARMAINC.-US6348474,2002,B1Locationinpatent:Pagecolumn90,91

219763-81-2

219763-82-3

[1]CurrentPatentAssignee:NIMBUSTHERAPEUTICSINC-WO2015/164374,2015,A1Locationinpatent:Paragraph00409;00412

[2]CurrentPatentAssignee:UNIVERSITYOFSOUTHCAROLINA-US2020/62728,2020,A1Locationinpatent:Paragraph0108;0110-0111

[3]Zhang,Li;Cheng,Chen;Li,Jing;Wang,Lili;Chumanevich,AlexanderA.;Porter,DonaldC.;Mindich,Aleksei;Gorbunova,Svetlana;Roninson,IgorB.;Chen,Mengqian;McInnes,Campbell[JournalofMedicinalChemistry,2022,vol.65,#4,p.3420-3433]

[4]Locationinpatent:schemeortableLengyel,László;Nagy,TiborZs.;Sipos,Gellért;Jones,Richard;Dormán,György;Ürge,László;Darvas,Ferenc[TetrahedronLetters,2012,vol.53,#7,p.738-743]

[5]Madrid,PeterB.;Sherrill,John;Liou,AllyP.;Weisman,JenniferL.;DeRisi,JosephL.;Guy,R.Kiplin[BioorganicandMedicinalChemistryLetters,2005,vol.15,#4,p.1015-1018]

[6]Tenora,Lukáš;Galeta,Juraj;Řezníčková,Eva;Kryštof,Vladimír;Potáček,Milan[JournalofOrganicChemistry,2016,vol.81,#23,p.11841-11856]

[7]CurrentPatentAssignee:ASTELLASPHARMAINC.-US6348474,2002,B1Locationinpatent:Pagecolumn90

2033-24-1

873-74-5

219763-82-3

[1]Margolis,BrandonJ.;Long,KimberlyA.;Laird,DanaL.T.;Ruble,J.Craig;Pulley,ShonR.[JournalofOrganicChemistry,2007,vol.72,#6,p.2232-2235]

642477-81-4

642477-82-5

[1]JournalofOrganicChemistry,2007,vol.72,p.2232-2235

[2]JournalofOrganicChemistry,2016,vol.81,p.11841-11856

219763-82-3

4-(4-diethylamino-1-methylbutylamino)quinoline-6-carbonitrile

[1]Margolis,BrandonJ.;Long,KimberlyA.;Laird,DanaL.T.;Ruble,J.Craig;Pulley,ShonR.[JournalofOrganicChemistry,2007,vol.72,#6,p.2232-2235]

219763-82-3 | 4-Hydroxyquinoline-6-carbonitrile