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2200214-93-1
Catalog No.:AA01K4K6

2200214-93-1 | SHP099 hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$94.00   $66.00
- +
5mg
95%
1 week  
$139.00   $97.00
- +
10mg
95%
1 week  
$170.00   $119.00
- +
25mg
95%
1 week  
$260.00   $182.00
- +
50mg
95%
1 week  
$354.00   $248.00
- +
100mg
95%
1 week  
$600.00   $420.00
- +
500mg
95%
1 week  
$1,258.00   $880.00
- +
1g
95%
1 week  
$1,646.00   $1,152.00
- +
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Technical Information
Catalog Number:
AA01K4K6
Chemical Name:
SHP099 hydrochloride
CAS Number:
2200214-93-1
Molecular Formula:
C16H20Cl3N5
Molecular Weight:
388.7225
SMILES:
CC1(CCN(CC1)C2=CN=C(C(=N2)N)C3=C(C(=CC=C3)Cl)Cl)N.Cl
Properties

Literature

Title: Garcia Fortanet J, et al. Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor. J Med Chem. 2016 Sep 8;59(17):7773-82.

Title: Chen YN, et al. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature. 2016 Jul 7;535(7610):148-52.

Title: Carmine Fedele, et al. SHP2 Inhibition Abrogates MEK inhibitor Resistance in Multiple Cancer Models. bioRxiv. April 25, 2018.

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SDS
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