Name: Name:3-(Trifluoromethoxy)benzenesulfonyl chloride
Brand: AABLOCKS
SKU: AA003B7L
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA003B7L

Chemical Name: 3-(Trifluoromethoxy)benzenesulfonyl chloride

CAS Number: 220227-84-9

Molecular Formula: C7H4ClF3O3S

Molecular Weight: 260.6181

MDL Number: MFCD01091016

SMILES: FC(Oc1cccc(c1)S(=O)(=O)Cl)(F)F

Properties

BP: 229-230 °C(lit.)

Form: Solid

MP: 229-230℃

Refractive Index: n20/D 1.4760(lit.)

Stability: Moisture Sensitive

Storage: 2-8℃;

Complexity: 308

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 15

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.9

52:

Downstream Synthesis Route

220227-84-9

686717-51-1

N-{3-4-(3-cyclopentyloxy-4-methoxy-phenyl)-2-oxo-pyrrolidin-1-yl-phenyl}-3-trifluoromethoxy-benzenesulfonamide

[1]Wu,Baogen;Kuhen,Kelli;NgocNguyen,Truc;Ellis,David;Anaclerio,Beth;He,Xiaohui;Yang,Kunyong;Karanewsky,Donald;Yin,Hong;Wolff,Karen;Bieza,Kimberly;Caldwell,Jeremy;He,Yun[BioorganicandMedicinalChemistryLetters,2006,vol.16,#13,p.3430-3433]

220227-84-9

562075-34-7

2-(3-trifluoromethoxy-benzenesulfonylimino)-imidazolidine-1-carbodithioicacid3-thioxo-5,6-dihydro-imidazo2,1-c1,2,4thiadiazol-7-ylester

[1]Saczewski,Jaroslaw;Brzozowski,Zdzialaw;Saczewski,Franciszek;Bednarski,PatrickJ.;Liebeke,Manuel;Gdaniec,Maria[BioorganicandMedicinalChemistryLetters,2006,vol.16,#14,p.3663-3667]

220227-84-9

578-54-1

120-20-7

79-08-3

N-2-(3,4-dimethoxy-phenyl)-ethyl-2-(2-ethyl-phenyl)-(3-trifluoromethoxy-benzenesulfonyl)-amino-acetamide

[1]McKeown,StephenC.;Hall,Adrian;Blunt,Richard;Brown,SusanH.;Chessell,IainP.;Chowdhury,Anita;Giblin,GerardM.P.;Healy,MarkP.;Johnson,MatthewR.;Lorthioir,Olivier;Michel,AntonD.;Naylor,Alan;Lewell,Xiao;Roman,Shilina;Watson,StephenP.;Winchester,WendyJ.;Wilson,RichardJ.[BioorganicandMedicinalChemistryLetters,2007,vol.17,#6,p.1750-1754]

220227-84-9

883901-38-0

N-4-((S)-1-propyl-pyrrolidin-3-yl)-phenyl-3-trifluoromethoxy-benzenesulfonamide

[1]CurrentPatentAssignee:ABBVIEINC-WO2007/118899,2007,A1Locationinpatent:Page/Pagecolumn145-146

220227-84-9

954376-45-5

N-3-((S)-1-benzyl-pyrrolidin-3-yl)-phenyl-3-trifluoromethoxy-benzenesulfonamide

[1]CurrentPatentAssignee:ABBVIEINC-WO2007/118899,2007,A1Locationinpatent:Page/Pagecolumn148