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220941-93-5,MFCD07363967
Catalog No.:AA00C2KT

220941-93-5 | 5-Fluoro-2-[[4-(2-pyridinyl)-1-piperazinyl]Methyl]-1H-indole

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$42.00   $29.00
- +
5mg
≥98%
in stock  
$183.00   $128.00
- +
10mg
≥98%
in stock  
$322.00   $225.00
- +
25mg
99%
in stock  
$617.00   $432.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2KT
Chemical Name:
5-Fluoro-2-[[4-(2-pyridinyl)-1-piperazinyl]Methyl]-1H-indole
CAS Number:
220941-93-5
Molecular Formula:
C18H19FN4
Molecular Weight:
310.3687
MDL Number:
MFCD07363967
SMILES:
Fc1ccc2c(c1)cc([nH]2)CN1CCN(CC1)c1ccccn1
Properties
Properties
 
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
385  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.9  

Literature

Title: Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain.

Journal: Molecular pharmacology 20041201

Title: Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.

Journal: Journal of medicinal chemistry 20040715

Title: Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning.

Journal: Journal of medicinal chemistry 20040422

Title: Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine.

Journal: The Journal of pharmacology and experimental therapeutics 20040101

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Tags:220941-93-5 Molecular Formula|220941-93-5 MDL|220941-93-5 SMILES|220941-93-5 5-Fluoro-2-[[4-(2-pyridinyl)-1-piperazinyl]Methyl]-1H-indole