Home Amines 22252-43-3
22252-43-3,MFCD00151456
Catalog No.:AA003NA0

22252-43-3 | 7-Amino-3-methyl-3-cephem-4-carboxylic acid

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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003NA0
Chemical Name:
7-Amino-3-methyl-3-cephem-4-carboxylic acid
CAS Number:
22252-43-3
Molecular Formula:
C8H10N2O3S
Molecular Weight:
214.2416
MDL Number:
MFCD00151456
SMILES:
O=C1[C@@H](N)[C@@H]2N1C(=C(CS2)C)C(=O)O
Properties
Properties
 
BP:
517.6°C at 760 mmHg  
Form:
Solid  
MP:
234 °C(dec.)  
Refractive Index:
104 ° (C=1, 1mol/L HCl)  
Solubility:
Do you have solubility information on this product that you would like to share  
Storage:
Keep in dry area;Room Temperature;  


Upstream Synthesis Route

[1]Patent:CN106831821,2017,A,.Locationinpatent:Paragraph0025;0026;0029;0030;0033;0034;0037-0039

[1]TetrahedronLetters,2000,vol.41,#20,p.3899-3901

[1]AdvancedSynthesisandCatalysis,2003,vol.345,#6-7,p.783-789

[2]JournalofMolecularCatalysisB:Enzymatic,2012,vol.76,p.52-58

[1]TetrahedronLetters,2000,vol.41,#20,p.3899-3901

[1]Patent:WO2012/32040,2012,A1,.Locationinpatent:Page/Pagecolumn10-11

[2]JournalofMolecularCatalysisB:Enzymatic,2012,vol.76,p.52-58

Downstream Synthesis Route

[1]PharmaceuticalChemistryJournal,1992,vol.26,p.169-173    Khimiko-FarmatsevticheskiiZhurnal,1992,vol.26,p.54-56

[1]PharmaceuticalChemistryJournal,1992,vol.26,p.169-173    Khimiko-FarmatsevticheskiiZhurnal,1992,vol.26,p.54-56

[1]IlFarmaco,1994,vol.49,p.201-204

[1]ChemistryofHeterocyclicCompounds,1984,vol.20,p.256-261    KhimiyaGeterotsiklicheskikhSoedinenii,1984,vol.20,p.321-326

22252-43-3    69651-48-5   
L-cefadroxil 

[1]ArchivderPharmazie,1994,vol.327,p.805-807

Literature

Title: Linda G Otten, et al. Mutational Analysis of a Key Residue in the Substrate Specificity of a Cephalosporin Acylase. Chembiochem. 2004 Jun 7;5(6):820-5.

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