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Home Other Building Blocks 2225819-06-5
2225819-06-5,MFCD31692414
Catalog No.:AA01EOHN

2225819-06-5 | BAY-2402234

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$139.00   $97.00
- +
5mg
97%
in stock  
$394.00   $276.00
- +
25mg
≥98%
in stock  
$1,883.00   $1,318.00
- +
100mg
99%
in stock  
$6,422.00   $4,495.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EOHN
Chemical Name:
BAY-2402234
CAS Number:
2225819-06-5
Molecular Formula:
C21H18ClF5N4O4
Molecular Weight:
520.8370
MDL Number:
MFCD31692414
SMILES:
CCn1c(CO)nn(c1=O)c1cc(O[C@H](C(F)(F)F)C)c(cc1F)C(=O)Nc1c(F)cccc1Cl
Properties
Computed Properties
 
Complexity:
819  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:MASSGENERALBRIGHAMINC;HARVARDUNIVERSITY;BROADINSTITUTE;BAYERAG-WO2018/77923,2018,A1Locationinpatent:Page/Pagecolumn371-372

[2]CurrentPatentAssignee:BROADINSTITUTE;BAYERAG-US2019/307728,2019,A1Locationinpatent:Paragraph0241-0244

[3]CurrentPatentAssignee:BAYERAG-WO2019/197269,2019,A1Locationinpatent:Page/Pagecolumn61

[4]CurrentPatentAssignee:BAYERAG-EP3553052,2019,A1Locationinpatent:Paragraph0189-0190

[1]CurrentPatentAssignee:BROADINSTITUTE;BAYERAG-US2019/307728,2019,A1

[2]CurrentPatentAssignee:BAYERAG-WO2019/197269,2019,A1

[3]CurrentPatentAssignee:BAYERAG-EP3553052,2019,A1

133541-45-4   
N-(2-chloro-6-fluorophenyl)-4-4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl-5-fluoro-2-(2S)-1,1,1-trifluoropropan-2-yloxy}benzamide 

[1]Patent:US2019/307728,2019,A1

[2]Patent:WO2019/197269,2019,A1

[3]Patent:EP3553052,2019,A1

[1]CurrentPatentAssignee:BROADINSTITUTE;BAYERAG-US2019/307728,2019,A1

[2]CurrentPatentAssignee:BAYERAG-WO2019/197269,2019,A1

[3]CurrentPatentAssignee:BAYERAG-EP3553052,2019,A1

[1]CurrentPatentAssignee:BAYERAG-WO2019/197239,2019,A1Locationinpatent:Page/Pagecolumn96-97

Literature

Title: Andreas Janzer, et al. Abstract DDT02-04: BAY 2402234: A novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of myeloid malignancies. AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL.

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SDS
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Tags:2225819-06-5 Molecular Formula|2225819-06-5 MDL|2225819-06-5 SMILES|2225819-06-5 BAY-2402234