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2230757-47-6
Catalog No.:AA01N185

2230757-47-6 | ACP-5862

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$527.00   $369.00
- +
5mg
98%
1 week  
$1,082.00   $758.00
- +
10mg
98%
1 week  
$1,558.00   $1,091.00
- +
50mg
98%
1 week  
$4,495.00   $3,147.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA01N185
Chemical Name:
ACP-5862
CAS Number:
2230757-47-6
Molecular Formula:
C26H23N7O3
Molecular Weight:
481.5059
SMILES:
CC#CC(=O)NCCCC(=O)c1nc(c2n1ccnc2N)c1ccc(cc1)C(=O)Nc1ccccn1
Properties

Literature

Title: Herman SE, et al. The Bruton's tyrosine kinase (BTK) inhibitor acalabrutinib demonstrates potent on-target effects and efficacy in two mouse models of chronic lymphocytic leukemia. Clin Cancer Res. 2016 Nov 30

Title: Diansong Zhou, et al. Evaluation of the Drug-Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP-5862, Using a Physiologically-Based Pharmacokinetic Modeling Approach. CPT Pharmacometrics Syst Pharmacol. 2019 Jul;8(7):489-499.

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SDS
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