Title: New PDE4 inhibitors based on pharmacophoric similarity between papaverine and tofisopam.
Journal: Bioorganic & medicinal chemistry letters 20111101
Title: Surface-assisted laser desorption/ionization mass spectrometry with a rotating ball interface.
Journal: Rapid communications in mass spectrometry : RCM 20110115
Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
Journal: Healthcare informatics research 20101201
Title: The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20101101
Title: Emerging pharmacologic therapies for irritable bowel syndrome.
Journal: Current gastroenterology reports 20101001
Title: Tenoten in the therapy of anxious disturbances in patients with essential hypertension and coronary heart disease.
Journal: Bulletin of experimental biology and medicine 20090801
Title: Benzodiazepine prescription and length of hospital stay at a Japanese university hospital.
Journal: BioPsychoSocial medicine 20090101
Title: [Grandaxin in neurological practice].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Journal: Journal of medicinal chemistry 20080124
Title: Clinical trial: dextofisopam in the treatment of patients with diarrhoea-predominant or alternating irritable bowel syndrome.
Journal: Alimentary pharmacology & therapeutics 20080115
Title: Tofisopam inhibits the pharmacokinetics of CYP3A4 substrate midazolam.
Journal: European journal of clinical pharmacology 20080101
Title: Application of drug repositioning strategy to TOFISOPAM.
Journal: Current medicinal chemistry 20080101
Title: In vitro prediction and in vivo verification of enantioselective human tofisopam metabolite profiles.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001
Title: Various effects of antidepressant drugs on bone microarchitectecture, mechanical properties and bone remodeling.
Journal: Toxicology and applied pharmacology 20070515
Title: Method validation and determination of enantiomers and conformers in tofisopam drug substances and drug products by chiral high-performance liquid chromatography and kinetic and thermodynamic study of the interconversion of the conformers.
Journal: Journal of chromatography. A 20060929
Title: Effect of tofisopam on the single-oral-dose pharmacokinetics and pharmacodynamics of the cyp3a4 probe drug alprazolam.
Journal: European journal of clinical pharmacology 20060701
Title: Gas chromatography nitrogen phosphorous detection (GC-NPD) assay of tofisopam in human plasma for pharmacokinetic evaluation.
Journal: Journal of pharmaceutical and biomedical analysis 20060616
Title: [Climacteric disorders].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060401
Title: [Tofisopam and melatonin attenuate the reorganization of circadian locomotor rhythm in rats under injection-induced stress conditions].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20060101
Title: Contribution of human hepatic cytochrome p450 isoforms to the metabolism of psychotropic drugs.
Journal: Biological & pharmaceutical bulletin 20050901
Title: [Fluctuations of the antianxiety effect of valerian and grandaxin during daytime wakefulness in humans with different chronotypes].
Journal: Fiziologiia cheloveka 20050101
Title: Risk and benefit of drug use during pregnancy.
Journal: International journal of medical sciences 20050101
Title: [The effect of tofisopam and tinctura leonuri on the color-discrimination function in young humans].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20050101
Title: [Chronobiological peculiarities of tofisopam action on human heart rate variability].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20050101
Title: [Effect of tofisopam on CYP3A4 enzyme activity on human recombinant 3A4 supersome].
Journal: Acta pharmaceutica Hungarica 20050101
Title: [Use of grandaxin in hypermotor dysfunction of the biliary ducts in young people].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20050101
Title: [Use of grandaxine in the treatment of patients with erosive-ulcerative stomach and gastroduodenal lesions].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20040101
Title: [Peculiarities in the effect of tofisopam and valerian extract on short-term memory and anxiety states in healthy humans].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101
Title: [A case in which tofisopam was effective for treatment of paroxysmal supraventricular tachycardia].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030501
Title: Species-dependency in chiral-drug recognition of serum albumin studied by chromatographic methods.
Journal: Journal of biochemical and biophysical methods 20021231
Title: Analysis of tofisopam in human serum by column-switching semi-micro high-performance liquid chromatography and evaluation of tofisopam bioequivalency.
Journal: Biomedical chromatography : BMC 20020601
Title: A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy.
Journal: European journal of obstetrics, gynecology, and reproductive biology 20020310
Title: Immunomodulating effects of tofizopam (Grandaxin) and diazepam in vitro.
Journal: Mediators of inflammation 20020201
Title: Highlights of CNS research at IDR: 2,3-benzodiazepines.
Journal: Die Pharmazie 20011001
Title: Tofisopam--evaluation of mutagenic and genotoxic properties.
Journal: Acta poloniae pharmaceutica 20010101
Title: [Highlights of CNS research at IDR: 2,3-benzodiazepines].
Journal: Acta pharmaceutica Hungarica 20010101
