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Home Amines 2239273-34-6
2239273-34-6,MFCD32263040
Catalog No.:AA01K3DP

2239273-34-6 | 3-[2-Amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methylbenzonitrile

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$168.00   $117.00
- +
10mg
≥98%
in stock  
$300.00   $210.00
- +
25mg
≥98%
in stock  
$662.00   $463.00
- +
50mg
98%
in stock  
$902.00   $632.00
- +
100mg
98%
in stock  
$1,277.00   $894.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01K3DP
Chemical Name:
3-[2-Amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methylbenzonitrile
CAS Number:
2239273-34-6
Molecular Formula:
C23H22N8O
Molecular Weight:
426.4738
MDL Number:
MFCD32263040
SMILES:
N#CC1=CC=CC(C2=NC(N)=NC(C3=CN(CC4=NC(C(C)(O)C)=CC=C4)N=N3)=C2)=C1C
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2018/136700,2018,A1

[2]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2019/161054,2019,A1

[3]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2020/18680,2020,A1

[4]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[5]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[6]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[7]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2020/247789,2020,A1

[1]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2018/136700,2018,A1

[2]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2019/161054,2019,A1

[3]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[4]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[1]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2018/136700,2018,A1Locationinpatent:Paragraph0274

[2]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2019/161054,2019,A1Locationinpatent:Paragraph0205;0211

[3]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2020/18680,2020,A1Locationinpatent:Paragraph0207;0213

[4]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2020/247789,2020,A1Locationinpatent:Paragraph0078

[5]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

933791-33-4   
3-2-amino-6-(1-6-(2-hydroxypropan-2-yl)pyridin-2-ylmethyl}-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl-2-methylbenzonitrile 

[1]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2018/136700,2018,A1

[2]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[3]CurrentPatentAssignee:EIKUIBIOLOGICALSCIENCE;ARCUSBIOSCIENCESINC-WO2020/247789,2020,A1

[1]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2018/136700,2018,A1

[2]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2019/161054,2019,A1

[3]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2020/18680,2020,A1

[4]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[5]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[6]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[7]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[8]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[9]Debien,LaurentP.P.;Jeffrey,JennaL.;Leleti,ManmohanR.;Miles,DillonH.;Powers,JayP.;Rosen,BrandonR.;Sharif,EhesanU.[Organicprocessresearchanddevelopment,2020,vol.24,#7,p.1254-1261]

[10]CurrentPatentAssignee:ARCUSBIOSCIENCESINC-WO2020/247789,2020,A1

Literature

Title: Seitz L, et al. Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers. Invest New Drugs. 2019 Aug;37(4):711-721.

Title: Daniel DiRenzo, et al. AB928, a dual antagonist of the A2aR and A2bR adenosine receptors, relieves adenosine-mediated immune suppression [abstract

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Tags:2239273-34-6 Molecular Formula|2239273-34-6 MDL|2239273-34-6 SMILES|2239273-34-6 3-[2-Amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methylbenzonitrile