[1]JournalofOrganicChemistry,1986,vol.51,p.3211-3213
Title: Multiple drug transporters mediate the placental transport of sulpiride.
Journal: Archives of toxicology 20171201
Title: Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells.
Journal: Oncotarget 20170214
Title: Determinants of orofacial clefting I: Effects of 5-Aza-2'-deoxycytidine on cellular processes and gene expression during development of the first branchial arch.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20170101
Title: Determinants of orofacial clefting II: Effects of 5-Aza-2'-deoxycytidine on gene methylation during development of the first branchial arch.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20170101
Title: Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells.
Journal: PloS one 20170101
Title: Function of DNA methyltransferase 3a in lead (Pb(2+) )-Induced Cyclooxygenase-2 gene.
Journal: Environmental toxicology 20150901
Title: Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Journal: Toxicology and applied pharmacology 20140915
Title: DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2.
Journal: Toxicology 20140902
Title: Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation.
Journal: Archives of toxicology 20140801
Title: Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126).
Journal: International journal of molecular sciences 20140801
Title: Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.
Journal: Cell reports 20140724
Title: The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.
Journal: Toxicology letters 20140605
Title: Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma.
Journal: Epigenetics 20140401
Title: [Effect of arsenic trioxide and 5-aza-2'-deoxycytidine on SHP-1, JAK3, TYK2 gene expression in K562 cells].
Journal: Zhongguo shi yan xue ye xue za zhi 20140401
Title: SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages.
Journal: Toxicology letters 20140321
Title: Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue.
Journal: Nutrition and cancer 20140101
Title: Epigenetic regulation of sox30 is associated with testis development in mice.
Journal: PloS one 20140101
Title: Inhibition of DNA methylation attenuates low-dose cadmium-induced cardiac contractile and intracellular Ca(2+) anomalies.
Journal: Clinical and experimental pharmacology & physiology 20131001
Title: Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis.
Journal: Cell death & disease 20130901
Title: Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.
Journal: The Journal of biological chemistry 20130816
Title: 5-Aza-2'-deoxycytidine inhibited PDGF-induced rat airway smooth muscle cell phenotypic switching.
Journal: Archives of toxicology 20130501
Title: A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons.
Journal: CNS neuroscience & therapeutics 20130301
Title: Increased PRAME-specific CTL killing of acute myeloid leukemia cells by either a novel histone deacetylase inhibitor chidamide alone or combined treatment with decitabine.
Journal: PloS one 20130101
Title: 5-aza-CdR induces the demethylation of Syk promoter in nasopharyngeal carcinoma cell.
Journal: Gene 20121215
Title: Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression.
Journal: Investigational new drugs 20121201
Title: Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
Journal: The Prostate 20121201
Title: Hypoxia-inducible factor-1α expression indicates poor prognosis in myelodysplastic syndromes.
Journal: Leukemia & lymphoma 20121201
Title: Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor.
Journal: International journal of molecular medicine 20121201
Title: Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma.
Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20121101
Title: Refractory anemia with ring sideroblasts associated with marked thrombocytosis harboring cytogenetic abnormality dup(2)(p15p22) treated with decitabine.
Journal: Leukemia & lymphoma 20121101
Title: Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma.
Journal: Biochimie 20121101
Title: Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.
Journal: Hepatology (Baltimore, Md.) 20121101
Title: PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation.
Journal: Genes, chromosomes & cancer 20121101
Title: Synergism between clofarabine and decitabine through p53R2: a pharmacodynamic drug-drug interaction modeling.
Journal: Leukemia research 20121101
Title: Could decitabine treatment impair memory functions in humans?
Journal: Medical hypotheses 20121101
Title: Epigenetic mechanisms regulate the prostaglandin E receptor 2 in breast cancer.
Journal: The Journal of steroid biochemistry and molecular biology 20121101
Title: Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer.
Journal: Oncology reports 20121101
Title: Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabine.
Journal: Bioorganic & medicinal chemistry letters 20121101
Title: Methylation subtypes and large-scale epigenetic alterations in gastric cancer.
Journal: Science translational medicine 20121017
Title: DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.
Journal: International journal of cancer 20121001
Title: Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells.
Journal: DNA and cell biology 20121001
Title: Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34+ cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine.
Journal: Annals of hematology 20121001
Title: Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines.
Journal: Experimental hematology 20121001
Title: Comprehensive DNA methylation analysis of benign and malignant adrenocortical tumors.
Journal: Genes, chromosomes & cancer 20121001
Title: 14-3-3σ mediates G2-M arrest produced by 5-aza-2'-deoxycytidine and possesses a tumor suppressor role in endometrial carcinoma cells.
Journal: Gynecologic oncology 20121001
Title: Phase I/II study of decitabine in patients with myelodysplastic syndrome: a multi-center study in Japan.
Journal: Cancer science 20121001
Title: Enforced expression of RASAL1 suppresses cell proliferation and the transformation ability of gastric cancer cells.
Journal: Oncology reports 20121001
Title: Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.
Journal: Molecular cancer therapeutics 20121001
Title: DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats.
Journal: Toxicology and applied pharmacology 20121001
Title: Increased cleavage rate of human nuclear transfer embryos after 5-aza-2'-deoxycytidine treatment.
Journal: Reproductive biomedicine online 20121001
Title: CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer.
Journal: Cancer biology & therapy 20121001
Title: Decitabine, a DNA methyltransferase inhibitor, reduces P-glycoprotein mRNA and protein expressions and increases drug sensitivity in drug-resistant MOLT4 and Jurkat cell lines.
Journal: Anticancer research 20121001
Title: Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update.
Journal: Seminars in hematology 20121001
Title: [Methylation of FHIT gene promoter region in DNA from plasma of patients with myelodysplastic syndromes and demethylating effect of decitabine].
Journal: Zhongguo shi yan xue ye xue za zhi 20121001
Title: Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications.
Journal: British journal of cancer 20120925
Title: Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia.
Journal: Blood 20120920
Title: Clofarabine plus low-dose cytarabine followed by clofarabine plus low-dose cytarabine alternating with decitabine in acute myeloid leukemia frontline therapy for older patients.
Journal: Cancer 20120915
Title: Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells.
Journal: Biochemical and biophysical research communications 20120914
Title: Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs.
Journal: Biochemical and biophysical research communications 20120914
Title: Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions.
Journal: Molecular pharmaceutics 20120904
Title: Clonal cytogenetic abnormalities after tyrosine kinase inhibitor therapy in Ph+ ALL resolution after decitabine therapy.
Journal: Pediatric blood & cancer 20120901
Title: A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer.
Journal: European journal of cancer (Oxford, England : 1990) 20120901
Title: Differential effects of low-dose decitabine on immune effector and suppressor responses in melanoma-bearing mice.
Journal: Cancer immunology, immunotherapy : CII 20120901
Title: Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells.
Journal: Oncology reports 20120901
Title: Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation.
Journal: International journal of oncology 20120901
Title: Targeting the MAGE A3 antigen in pancreatic cancer.
Journal: Surgery 20120901
Title: Genomic methylation profiling combined with gene expression microarray reveals the aberrant methylation mechanism involved in nasopharyngeal carcinoma taxol resistance.
Journal: Anti-cancer drugs 20120901
Title: 5'-Aza-dC sensitizes paraquat toxic effects on PC12 cell.
Journal: Neuroscience letters 20120822
Title: Improving the outlook for myelodysplastic syndrome.
Journal: Journal of the National Cancer Institute 20120822
Title: CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells.
Journal: International journal of cancer 20120815
Title: MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma.
Journal: International journal of cancer 20120815
Title: Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators.
Journal: Toxicology and applied pharmacology 20120815
Title: Case report of isochromosome 17q in acute myeloid leukemia with myelodysplasia-related changes after treatment with a hypomethylating agent.
Journal: Genetics and molecular research : GMR 20120806
Title: Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes.
Journal: Investigational new drugs 20120801
Title: Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.
Journal: International journal of cancer 20120801
Title: Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.
Journal: Genes, chromosomes & cancer 20120801
Title: Cell cycle regulation of human endometrial stromal cells during decidualization.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20120801
Title: A patient with acute megakaryoblastic leukaemia who achieved CRi after decitabine treatment.
Journal: Leukemia research 20120801
Title: Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells.
Journal: International journal of oncology 20120801
Title: 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
Journal: Oncology reports 20120801
Title: The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer.
Journal: Epigenetics 20120801
Title: Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.
Journal: The Journal of biological chemistry 20120720
Title: Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120720
Title: Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy.
Journal: International journal of radiation oncology, biology, physics 20120715
Title: Promoter demethylation of Keap1 gene in human diabetic cataractous lenses.
Journal: Biochemical and biophysical research communications 20120706
Title: Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo.
Journal: International journal of cancer 20120701
Title: Durable complete remission after single agent decitabine in AML relapsing in extramedullary sites after allo-SCT.
Journal: Bone marrow transplantation 20120701
Title: Rap1GAP regulates renal cell carcinoma invasion.
Journal: Cancer letters 20120701
Title: 5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis.
Journal: Molecular & cellular proteomics : MCP 20120701
Title: Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir-145.
Journal: The Journal of dermatology 20120701
Title: cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120701
Title: Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.
Journal: Laboratory investigation; a journal of technical methods and pathology 20120701
Title: Assessing signaling pathways associated with in vitro resistance to cytotoxic agents in AML.
Journal: Leukemia research 20120701
Title: Epigenetics and vitrification of embryos: one step forward and many raised equivocal questions.
Journal: Fertility and sterility 20120701
Title: Epigenetic inactivation of PLCD1 in chronic myeloid leukemia.
Journal: International journal of molecular medicine 20120701
Title: Effect of 5-aza-2'-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos.
Journal: Fertility and sterility 20120701
Title: 5-aza-2'-deoxycytidine improves the sensitivity of endometrial cancer cells to progesterone therapy.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20120701
Title: Myelodysplastic syndromes: therapy and outlook.
Journal: The American journal of medicine 20120701
Title: Immunization with WT1-derived peptides by tattooing inhibits the growth of TRAMP-C2 prostate tumor in mice.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20120701
Title: Prostaglandin E2 induces growth inhibition, apoptosis and differentiation in T and B cell-derived acute lymphoblastic leukemia cell lines (CCRF-CEM and Nalm-6).
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120701
Title: Expression and functions of μ-opioid receptors and cannabinoid receptors type 1 in T lymphocytes.
Journal: Annals of the New York Academy of Sciences 20120701
Title: [Effective treatment of myelodysplastic syndromes-refractory anemia with excess blasts type II by decitabine: a case report].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120701
Title: Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia.
Journal: Blood 20120621
Title: Development and validation of a liquid chromatography-tandem mass spectrometry method for quantification of decitabine in rat plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120615
Title: XAF1 is frequently methylated in human esophageal cancer.
Journal: World journal of gastroenterology 20120614
Title: Correlation between T-cadherin gene expression and aberrant methylation of T-cadherin promoter in human colon carcinoma cells.
Journal: Medical oncology (Northwood, London, England) 20120601
Title: Reactivation of Syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells.
Journal: Medical oncology (Northwood, London, England) 20120601
Title: Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells.
Journal: The Journal of nutritional biochemistry 20120601
Title: Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers.
Journal: International journal of cancer 20120601
Title: Epigenetic silencing of the tumor suppressor klotho in human breast cancer.
Journal: Breast cancer research and treatment 20120601
Title: Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line.
Journal: Molecular and cellular biochemistry 20120601
Title: Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study.
Journal: Cancer chemotherapy and pharmacology 20120601
Title: TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma.
Journal: EMBO molecular medicine 20120601
Title: microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis.
Journal: Oncology reports 20120601
Title: Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle.
Journal: Cellular reprogramming 20120601
Title: DNA demethylating agent decitabine increases AQP5 expression and restores salivary function.
Journal: Journal of dental research 20120601
Title: Chronic myelomonocytic leukemia: 2012 update on diagnosis, risk stratification, and management.
Journal: American journal of hematology 20120601
Title: Pharmacological unmasking microarray approach-based discovery of novel DNA methylation markers for hepatocellular carcinoma.
Journal: Journal of Korean medical science 20120601
Title: [Effect of proliferation inhibition and PTEN gene expression induced by decitabine combined with daunorubicin on HL-60 cell line].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120601
Title: Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo.
Journal: Oncogene 20120531
Title: Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.
Journal: Blood 20120531
Title: Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells.
Journal: World journal of gastroenterology 20120521
Title: Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication.
Journal: World journal of gastroenterology 20120507
Title: Epigenetic regulation of 5-lipoxygenase in the phenotypic plasticity of valvular interstitial cells associated with aortic valve stenosis.
Journal: FEBS letters 20120507
Title: 5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand.
Journal: Blood 20120503
Title: Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma.
Journal: Cell biology international 20120501
Title: Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501
Title: DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia.
Journal: Leukemia 20120501
Title: Proteomic analysis identifies differentially expressed proteins in AML1/ETO acute myeloid leukemia cells treated with DNMT inhibitors azacitidine and decitabine.
Journal: Leukemia research 20120501
Title: Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.
Journal: International journal of oncology 20120501
Title: Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120501
Title: Epigenetic resensitization to platinum in ovarian cancer.
Journal: Cancer research 20120501
Title: [Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and methylation of CHFR in human laryngreal carcinoma cell line].
Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20120501
Title: The differentiating and apoptotic effects of 2-aza-5'-deoxycytidine are dependent on the PU.1 expression level in PU.1-transgenic K562 cells.
Journal: Biochemical and biophysical research communications 20120420
Title: [A case report of undifferentiated connective tissue disease associated myelodysplastic].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20120418
Title: Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells.
Journal: Biochemical and biophysical research communications 20120406
Title: Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth.
Journal: International journal of cancer 20120401
Title: MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice.
Journal: Molecular human reproduction 20120401
Title: Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401
Title: Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation.
Journal: Kidney international 20120401
Title: Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells.
Journal: Oncology reports 20120401
Title: SFRP1 promoter methylation and expression in human trabecular meshwork cells.
Journal: Experimental eye research 20120401
Title: Discovery of drugs that possess activity against feline leukemia virus.
Journal: The Journal of general virology 20120401
Title: Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1.
Journal: Antimicrobial agents and chemotherapy 20120401
Title: DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs.
Journal: Biochemical pharmacology 20120401
Title: Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.
Journal: American journal of hematology 20120401
Title: A simple method for high-throughput quantification of genome-wide DNA methylation by fluorescence polarization.
Journal: Epigenetics 20120401
Title: Promoter methylation regulates cigarette smoke-stimulated cyclooxygenase-2 expression in esophageal squamous cell carcinoma.
Journal: Journal of digestive diseases 20120401
Title: Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.
Journal: Cancer cell 20120320
Title: Identification of the A kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma.
Journal: Journal of surgical oncology 20120315
Title: Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
Title: Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.
Journal: Head & neck 20120301
Title: The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.
Journal: International journal of cancer 20120301
Title: Feasibility of hypomethylating agents followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome.
Journal: Bone marrow transplantation 20120301
Title: Aberrant methylation of RASSF2A in human pancreatic ductal adenocarcinoma and its relation to clinicopathologic features.
Journal: Pancreas 20120301
Title: Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression.
Journal: Digestive diseases and sciences 20120301
Title: A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy.
Journal: Haematologica 20120301
Title: DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells.
Journal: Cancer letters 20120301
Title: Downregulation of MUC1 expression and its recognition by CD8⁺ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi.
Journal: European journal of immunology 20120301
Title: Optimizing hypomethylating agents in myelodysplastic syndromes.
Journal: Current opinion in hematology 20120301
Title: 5-Aza-2'-deoxycytidine increases the sensitivity of human bone marrow mesenchymal stem cells to chemotherapeutic agents by demethylation of p73.
Journal: Journal of pediatric hematology/oncology 20120301
Title: Decitabine for acute myeloid leukemia.
Journal: Expert review of anticancer therapy 20120301
Title: [Effect of methylation inhibitor on EphB4 gene expression, proliferation and apoptosis in CEM cells].
Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20120301
Title: [Therapeutic effect of in vitro 5-aza-2'-deoxycytidine combined with imatinib on gastrointestinal stromal tumor].
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120301
Title: Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions.
Journal: PLoS genetics 20120301
Title: Position effect variegation and epigenetic modification of a transgene in a pig model.
Journal: Genetics and molecular research : GMR 20120216
Title: Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine.
Journal: Blood 20120202
Title: ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours.
Journal: Journal of cellular and molecular medicine 20120201
Title: CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors.
Journal: Leukemia 20120201
Title: Histone H4 deacetylation down-regulates catalase gene expression in doxorubicin-resistant AML subline.
Journal: Cell biology and toxicology 20120201
Title: Heparanase expression is associated with histone modifications in glioblastoma.
Journal: International journal of oncology 20120201
Title: Analysis of aberrant methylation in DNA repair genes during malignant transformation of human bronchial epithelial cells induced by cadmium.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120201
Title: Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Journal: Cancer prevention research (Philadelphia, Pa.) 20120201
Title: Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.
Journal: Molecular cancer research : MCR 20120201
Title: Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression.
Journal: European journal of oral sciences 20120201
Title: Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20120201
Title: [Decitabine for treatment of myelodysplastic syndrome in an elderly patient and review of literature].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201
Title: [Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line].
Journal: Zhongguo shi yan xue ye xue za zhi 20120201
Title: [The comparison of short-term efficacies between decitabine and HA regimen for MDS/AML patients].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120201
Title: DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.
Journal: International journal of cancer 20120115
Title: DNA methylation of the 5'-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells.
Journal: Biochemical and biophysical research communications 20120106
Title: HSPB8 is methylated in hematopoietic malignancies and overexpression of HSPB8 exhibits antileukemia effect.
Journal: Experimental hematology 20120101
Title: Epigenetic drug discovery: targeting DNA methyltransferases.
Journal: Journal of biomolecular screening 20120101
Title: A cost-effectiveness analysis of using azacitidine vs. decitabine in treating patients with myelodysplastic syndromes.
Journal: Journal of medical economics 20120101
Title: 5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120101
Title: Effect of 5-Aza-2'-deoxycytidine on SLC22A18 in glioma U251 cells.
Journal: Molecular medicine reports 20120101
Title: CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.
Journal: Experimental dermatology 20120101
Title: Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life.
Journal: Endocrinology 20120101
Title: Regulation of opioid and cannabinoid receptor genes in human neuroblastoma and T cells by the epigenetic modifiers trichostatin A and 5-aza-2'-deoxycytidine.
Journal: Neuroimmunomodulation 20120101
Title: [Demethylating medication in myelodysplastic syndrome].
Journal: Nederlands tijdschrift voor geneeskunde 20120101
Title: DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.
Journal: Chemotherapy 20120101
Title: Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.
Journal: Nucleosides, nucleotides & nucleic acids 20120101
Title: Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation.
Journal: Clinical laboratory 20120101
Title: Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Screening for epigenetically masked genes in colorectal cancer Using 5-Aza-2'-deoxycytidine, microarray and gene expression profile.
Journal: Cancer genomics & proteomics 20120101
Title: Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer.
Journal: PloS one 20120101
Title: DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
Journal: Radiation oncology (London, England) 20120101
Title: Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens.
Journal: PloS one 20120101
Title: Reversin increase the plasticity of bone marrow-derived mesenchymal stem cell for generation of cardiomyocyte in vitro.
Journal: Acta medica Indonesiana 20120101
Title: [5-aza-2'-deoxycytidine-induced inhibition of CDH13 expression and its inhibitory effect on methylation status in human colon cancer cells in vitro and on growth of xenograft in nude mice].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20120101
Title: Utility of DNA methyltransferase inhibitors for the treatment of myelodysplastic syndromes.
Journal: Current pharmaceutical design 20120101
Title: Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues.
Journal: PloS one 20120101
Title: Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.
Journal: PloS one 20120101
Title: Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia.
Journal: Journal of hematology & oncology 20120101
Title: The effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines.
Journal: PloS one 20120101
Title: Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma.
Journal: World journal of surgical oncology 20120101
Title: Transcriptional regulation of hTREX84 in human cancer cells.
Journal: PloS one 20120101
Title: 5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes.
Journal: PloS one 20120101
Title: Alterations of the WNT7A gene in clear cell renal cell carcinomas.
Journal: PloS one 20120101
Title: Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas.
Journal: PloS one 20120101
Title: Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.
Journal: PloS one 20120101
Title: MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats.
Journal: Toxicology 20111218
Title: 5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression.
Journal: Cancer letters 20111208
Title: The association between non-Hodgkin lymphoma and methylation of p73.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20111201
Title: Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine.
Journal: Cell biochemistry and function 20111201
Title: Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells.
Journal: Carcinogenesis 20111201
Title: Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer.
Journal: International journal of cancer 20111201
Title: The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.
Journal: Genes, chromosomes & cancer 20111201
Title: Epigenetic regulation of glucose transporter 4 by estrogen receptor β.
Journal: Molecular endocrinology (Baltimore, Md.) 20111201
Title: Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.
Journal: Epigenetics 20111201
Title: Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.
Journal: Oncotarget 20111201
Title: Epigenetic inactivation of the MIR34B/C in multiple myeloma.
Journal: Blood 20111124
Title: HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL.
Journal: Blood 20111117
Title: Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines.
Journal: International journal of cancer 20111115
Title: CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a.
Journal: The Biochemical journal 20111115
Title: Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111115
Title: MAGE: the spell is broken.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111115
Title: Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter.
Journal: FEBS letters 20111104
Title: Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line.
Journal: Biochemical and biophysical research communications 20111104
Title: Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells.
Journal: Breast cancer research and treatment 20111101
Title: 5-Aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression.
Journal: International journal of cancer 20111101
Title: A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma.
Journal: The European respiratory journal 20111101
Title: Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma.
Journal: Digestive diseases and sciences 20111101
Title: Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors.
Journal: British journal of pharmacology 20111101
Title: p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.
Journal: Leukemia 20111101
Title: Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer.
Journal: Breast cancer research and treatment 20111101
Title: γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines.
Journal: International journal of radiation biology 20111101
Title: WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix.
Journal: Carcinogenesis 20111101
Title: Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer.
Journal: Cancer research 20111101
Title: Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia.
Journal: American journal of hematology 20111101
Title: Decitabine, independent of apoptosis, exerts its cytotoxic effects on cell growth in melanoma cells.
Journal: Environmental toxicology and pharmacology 20111101
Title: 5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.
Journal: Epigenetics 20111101
Title: The effect of epigenetic factors on differentiation of pancreatic progenitor cells into insulin-producing cells.
Journal: Transplantation proceedings 20111101
Title: [The clinical research of treatment by decitabine moderate or high-risk myelodysplastic syndrome patients].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20111101
Title: 5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of transferrin receptor 1 (TfR1) and ferrochelatase (Fech) genes.
Journal: The Journal of biological chemistry 20111028
Title: FMR1 CGG repeat lengths mediate different regulation of reporter gene expression in comparative transient and locus specific integration assays.
Journal: Gene 20111015
Title: Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma.
Journal: World journal of gastroenterology 20111007
Title: Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.
Journal: Blood 20111006
Title: Aberrant CpG island hypermethylation and down-regulation of Oct-6 mRNA expression in human hepatocellular carcinoma.
Journal: Digestive diseases and sciences 20111001
Title: Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.
Journal: Cancer 20111001
Title: A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome.
Journal: Haematologica 20111001
Title: Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL.
Journal: Carcinogenesis 20111001
Title: Treatment of higher-risk myelodysplastic syndrome.
Journal: Seminars in oncology 20111001
Title: Failure of hypomethylating agent-based therapy in myelodysplastic syndromes.
Journal: Seminars in oncology 20111001
Title: [Novel therapeutics for myelodysplastic syndromes].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20111001
Title: [Silence mechanism of WT1 gene in leukemic cell line U937].
Journal: Zhongguo shi yan xue ye xue za zhi 20111001
Title: Epigenomics in hematopoietic transplantation: novel treatment strategies.
Journal: Epigenomics 20111001
Title: Successful allogeneic stem-cell transplantation in a patient with myelodysplastic syndrome with hemodialysis-dependent end-stage renal disease.
Journal: Transplantation 20110927
Title: Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
Journal: Oncogene 20110915
Title: Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.
Journal: Analytical chemistry 20110915
Title: A pilot study of subcutaneous decitabine in β-thalassemia intermedia.
Journal: Blood 20110908
Title: Hypomethylating agents for the treatment of acute myeloid leukemia in the elderly: for all, none, or which patients?
Journal: Cancer 20110901
Title: Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine.
Journal: Leukemia research 20110901
Title: Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells.
Journal: Molecular and cellular biochemistry 20110901
Title: Increased PRAME antigen-specific killing of malignant cell lines by low avidity CTL clones, following treatment with 5-Aza-2'-Deoxycytidine.
Journal: Cancer immunology, immunotherapy : CII 20110901
Title: MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing.
Journal: Cancer immunology, immunotherapy : CII 20110901
Title: Decreased expression of protease-activated receptor 4 in human gastric cancer.
Journal: The international journal of biochemistry & cell biology 20110901
Title: Transformation-dependent silencing of tumor-selective apoptosis-inducing TRAIL by DNA hypermethylation is antagonized by decitabine.
Journal: Molecular cancer therapeutics 20110901
Title: Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer.
Journal: Cancer biology & therapy 20110901
Title: Definition of the landscape of promoter DNA hypomethylation in liver cancer.
Journal: Cancer research 20110901
Title: NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
Journal: Carcinogenesis 20110901
Title: Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study.
Journal: American journal of hematology 20110901
Title: TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.
Journal: Epigenetics 20110901
Title: Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells.
Journal: Epigenetics 20110901
Title: Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Journal: Blood 20110811
Title: Identification of methylation profile of HOX genes in extrahepatic cholangiocarcinoma.
Journal: World journal of gastroenterology 20110807
Title: Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma.
Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110801
Title: Interferon-alpha induces reversible DNA demethylation of the interferon-induced transmembrane protein-3 core promoter in human melanoma cells.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110801
Title: DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
Journal: European journal of cancer (Oxford, England : 1990) 20110801
Title: Inhibition of p53-p21 pathway promotes the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes.
Journal: Molecular and cellular biochemistry 20110801
Title: The effects of 5-aza-2'- deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts.
Journal: Cellular reprogramming 20110801
Title: Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma.
Journal: Melanoma research 20110801
Title: MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer.
Journal: Carcinogenesis 20110801
Title: The effect of decitabine on megakaryocyte maturation and platelet release.
Journal: Thrombosis and haemostasis 20110801
Title: The depletion of DNA methyltransferase-1 and the epigenetic effects of 5-aza-2'deoxycytidine (decitabine) are differentially regulated by cell cycle progression.
Journal: Epigenetics 20110801
Title: Hematologic outcomes of myelodysplastic syndromes treatment with hypomethylating agents in community practice.
Journal: Clinical lymphoma, myeloma & leukemia 20110801
Title: [Hypomethylating agents for the treatment of myelodysplastic syndromes].
Journal: Bulletin du cancer 20110801
Title: [Effects of decitabine on biological behavior of U266 cells].
Journal: Zhongguo shi yan xue ye xue za zhi 20110801
Title: [Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110801
Title: The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines.
Journal: Experimental & molecular medicine 20110731
Title: Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells.
Journal: Toxicology 20110729
Title: Epigenetic mechanisms for silencing glutathione S-transferase m2 expression by hypermethylated specificity protein 1 binding in lung cancer.
Journal: Cancer 20110715
Title: MicroRNA-146a downregulates NFκB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110715
Title: Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia.
Journal: Cell cycle (Georgetown, Tex.) 20110715
Title: Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes.
Journal: Leukemia research 20110701
Title: Changes in the levels of DNA methylation in testis and liver of SD rats neonatally exposed to 5-aza-2'-deoxycytidine and cadmium.
Journal: Journal of applied toxicology : JAT 20110701
Title: The in vivo induction of sister chromatid exchange by the demethylating agent 5-aza-2'-deoxycytidine.
Journal: Mutagenesis 20110701
Title: DNMT3B gene amplification predicts resistance to DNA demethylating drugs.
Journal: Genes, chromosomes & cancer 20110701
Title: Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas.
Journal: Cancer science 20110701
Title: Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells.
Journal: Leukemia research 20110701
Title: EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
Title: Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110701
Title: The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy.
Journal: Cancer investigation 20110701
Title: [High glucose induce the demethylation of CTGF promoter and gene expression].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701
Title: [Epigenetic therapy in myelodysplastic syndromes].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20110701
Title: [Treatment of two chronic myelomonocytic leukemia patients with Decitabine].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110701
Title: Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway.
Journal: Molecules and cells 20110630
Title: Azacytidine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation.
Journal: International journal of cancer 20110615
Title: Activity of azacitidine in chronic myelomonocytic leukemia.
Journal: Cancer 20110615
Title: Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism.
Journal: The Journal of biological chemistry 20110603
Title: Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.
Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20110601
Title: Expression of the human cancer/testis antigen NY-SAR-35 is activated by CpG island hypomethylation.
Journal: Biotechnology letters 20110601
Title: Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.
Journal: Endocrine-related cancer 20110601
Title: Clinical significance of expression of Hint1 and potential epigenetic mechanism in gastric cancer.
Journal: International journal of oncology 20110601
Title: A demethylating agent enhances chemosensitivity to vinblastine in a xenograft model of renal cell carcinoma.
Journal: International journal of oncology 20110601
Title: Ultra-performance liquid chromatography/tandem mass spectrometry for accurate quantification of global DNA methylation in human sperms.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601
Title: Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.
Journal: The Journal of clinical investigation 20110601
Title: Use of hypomethylating agents and associated care in patients with myelodysplastic syndromes: a claims database study.
Journal: Current medical research and opinion 20110601
Title: 2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential.
Journal: Epigenetics 20110601
Title: Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520
Title: Acute myocarditis induced by hypomethylating agents.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510
Title: Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110501
Title: Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer.
Journal: International journal of molecular medicine 20110501
Title: Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.
Journal: Thyroid : official journal of the American Thyroid Association 20110501
Title: Pharmacokinetic evaluation of decitabine for the treatment of leukemia.
Journal: Expert opinion on drug metabolism & toxicology 20110501
Title: [Promoter methylation status of hPer3 gene in AML patients and the in vitro effect of decitabine on the status].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501
Title: [Reversal effect of 5-Aza-dc on cisplatin-resistance in human NSCLC cells in vitro].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501
Title: Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma.
Journal: International journal of cancer 20110415
Title: Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas.
Journal: Breast cancer research and treatment 20110401
Title: Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.
Journal: International journal of andrology 20110401
Title: Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome.
Journal: Leukemia research 20110401
Title: Aberrant methylation of the RIZ1 gene in myelodysplastic syndrome and acute myeloid leukemia.
Journal: Leukemia research 20110401
Title: Gene expression profiling of myelodysplastic CD34+ hematopoietic stem cells treated in vitro with decitabine.
Journal: Leukemia research 20110401
Title: Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial.
Journal: Annals of hematology 20110401
Title: Decitabine-induced apoptosis is derived by Puma and Noxa induction in chronic myeloid leukemia cell line as well as in PBL and is potentiated by SAHA.
Journal: Molecular and cellular biochemistry 20110401
Title: 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene.
Journal: The international journal of biochemistry & cell biology 20110401
Title: (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.
Journal: Carcinogenesis 20110401
Title: GPR54 is a target for suppression of metastasis in endometrial cancer.
Journal: Molecular cancer therapeutics 20110401
Title: Quantitative assessment of AKAP12 promoter methylation in human prostate cancer using methylation-sensitive high-resolution melting: correlation with Gleason score.
Journal: Urology 20110401
Title: Interleukin-6 expression was regulated by epigenetic mechanisms in response to influenza virus infection or dsRNA treatment.
Journal: Molecular immunology 20110401
Title: Abnormal methylation of histone deacetylase genes: implications on etiology and epigenetic therapy of astrocytomas.
Journal: Anticancer research 20110401
Title: Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2/-deoxycytidine and trichostatin A.
Journal: Theriogenology 20110315
Title: Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110315
Title: MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway.
Journal: Cancer research 20110315
Title: Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma.
Journal: Digestive diseases and sciences 20110301
Title: Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers.
Journal: Leukemia research 20110301
Title: Chronic exposure to cigarette smoke condensate in vitro induces epithelial to mesenchymal transition-like changes in human bronchial epithelial cells, BEAS-2B.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110301
Title: Novel agents for the treatment of acute myeloid leukemia in the older patient.
Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20110301
Title: Hypomethylating agents for urologic cancers.
Journal: Future oncology (London, England) 20110301
Title: Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract.
Journal: Human cell 20110301
Title: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
Journal: Toxicology and applied pharmacology 20110215
Title: Noncytotoxic differentiation treatment of renal cell cancer.
Journal: Cancer research 20110215
Title: Hypomethylating agents and other novel strategies in myelodysplastic syndromes.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210
Title: Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms.
Journal: DNA and cell biology 20110201
Title: DNA methyltransferase inhibition may limit cancer cell growth by disrupting ribosome biogenesis.
Journal: Epigenetics 20110201
Title: Fused-core silica column ultra-performance liquid chromatography-ion trap tandem mass spectrometry for determination of global DNA methylation status.
Journal: Analytical biochemistry 20110201
Title: Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy.
Journal: Biochemical pharmacology 20110201
Title: Successful resolution of acute myelogenous leukemia-associated hemophagocytic lymphohistiocytosis with decitabine.
Journal: Leukemia & lymphoma 20110201
Title: Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20110201
Title: Silence of HIN-1 expression through methylation of its gene promoter in gastric cancer.
Journal: World journal of gastroenterology 20110128
Title: High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).
Journal: Blood 20110120
Title: Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16.
Journal: Toxicology letters 20110115
Title: Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.
Journal: Biochemical and biophysical research communications 20110114
Title: Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.
Journal: Mutation research 20110110
Title: 3-Deazauridine enhances the antileukemic action of 5-aza-2'-deoxycytidine and targets drug-resistance due to deficiency in deoxycytidine kinase.
Journal: Leukemia research 20110101
Title: Reduced methyl-CpG protein binding contributing to miR-184 expression in umbilical cord blood CD4+ T-cells.
Journal: Leukemia 20110101
Title: Epigenetic silencing of somatostatin in gastric cancer.
Journal: Digestive diseases and sciences 20110101
Title: Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B.
Journal: Microbes and infection 20110101
Title: Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A.
Journal: Differentiation; research in biological diversity 20110101
Title: Demethylation of E-cadherin gene in nasopharyngeal carcinoma could serve as a potential therapeutic strategy.
Journal: Journal of biochemistry 20110101
Title: Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma.
Journal: Lung cancer (Amsterdam, Netherlands) 20110101
Title: Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.
Journal: Current medicinal chemistry 20110101
Title: Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel.
Journal: BMC cancer 20110101
Title: Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.
Journal: BMC cancer 20110101
Title: Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery.
Journal: PloS one 20110101
Title: Functional and sequence analysis of human neuroglobin gene promoter region.
Journal: Biochimica et biophysica acta 20110101
Title: Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines.
Journal: PloS one 20110101
Title: Genome-wide assessment of imprinted expression in human cells.
Journal: Genome biology 20110101
Title: [Progress in research on DNA methylation and laryngeal carcinoma].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20110101
Title: Proximity ligation in situ assay for monitoring the global DNA methylation in cells.
Journal: BMC biotechnology 20110101
Title: Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma.
Journal: BMC cancer 20110101
Title: Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.
Journal: BMC cancer 20110101
Title: Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure.
Journal: PloS one 20110101
Title: Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells.
Journal: PloS one 20110101
Title: Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation.
Journal: PloS one 20110101
Title: Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors.
Journal: BMC cancer 20110101
Title: DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells.
Journal: Molecular medicine reports 20110101
Title: Mechanisms of resistance to decitabine in the myelodysplastic syndrome.
Journal: PloS one 20110101
Title: Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors.
Journal: Oxidative medicine and cellular longevity 20110101
Title: Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors.
Journal: Cell adhesion & migration 20110101
Title: GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.
Journal: PloS one 20110101
Title: Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
Journal: Journal of translational medicine 20110101
Title: Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment.
Journal: PloS one 20110101
Title: Methylation of secreted frizzled related protein gene in acute leukemia patients in China.
Journal: Asian Pacific journal of cancer prevention : APJCP 20110101
Title: Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells.
Journal: Blood 20101223
Title: Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.
Journal: Blood 20101202
Title: DNA methylation and carcinogenesis of PRDM5 in cervical cancer.
Journal: Journal of cancer research and clinical oncology 20101201
Title: Expression, epigenetic regulation, and humoral immunogenicity of cancer-testis antigens in chronic myeloid leukemia.
Journal: Leukemia research 20101201
Title: Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia: Argentinian/South Korean multi-institutional clinical experience.
Journal: Leukemia & lymphoma 20101201
Title: Prodrugs of aza nucleosides based on proton transfer reaction.
Journal: Journal of computer-aided molecular design 20101201
Title: Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms.
Journal: Hepatology (Baltimore, Md.) 20101201
Title: Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer.
Journal: The American journal of pathology 20101201
Title: Pharmacologic induction of fetal hemoglobin production.
Journal: Hematology/oncology clinics of North America 20101201
Title: Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia.
Journal: Leukemia & lymphoma 20101201
Title: Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer.
Journal: Anticancer research 20101201
Title: Alphabet soup: RAEB, HMA, DOE, and AFOP.
Journal: Medicine and health, Rhode Island 20101201
Title: Economic analysis of decitabine versus best supportive care in the treatment of intermediate- and high-risk myelodysplastic syndromes from a US payer perspective.
Journal: Clinical therapeutics 20101201
Title: Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells.
Journal: Cell death & disease 20101201
Title: Epigenetic silencing of beta-spectrin, a TGF-beta signaling/scaffolding protein in a human cancer stem cell disorder: Beckwith-Wiedemann syndrome.
Journal: The Journal of biological chemistry 20101112
Title: Epigenetic regulation of miR-196b expression in gastric cancer.
Journal: Genes, chromosomes & cancer 20101101
Title: Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications.
Journal: Journal of hepatology 20101101
Title: Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20101101
Title: Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription.
Journal: Experimental hematology 20101101
Title: Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells.
Journal: Experimental dermatology 20101101
Title: The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells.
Journal: Human reproduction (Oxford, England) 20101101
Title: Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice.
Journal: Nature neuroscience 20101101
Title: Claudin-7 down-regulation is an important feature in oral squamous cell carcinoma.
Journal: Histopathology 20101101
Title: [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101
Title: Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription.
Journal: Oncogene 20101028
Title: The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers.
Journal: International journal of cancer 20101015
Title: Epigenetically altered wound healing in keloid fibroblasts.
Journal: The Journal of investigative dermatology 20101001
Title: Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study.
Journal: Pediatric blood & cancer 20101001
Title: [Expression, genetic and epigenetic alterations of LTF gene in nasopharyngeal carcinoma cell lines].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001
Title: Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 mice.
Journal: European journal of pharmacology 20100910
Title: Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents.
Journal: Molecular and cellular biochemistry 20100901
Title: A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer.
Journal: Cancer 20100901
Title: Exploiting drug repositioning for discovery of a novel HIV combination therapy.
Journal: Journal of virology 20100901
Title: Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation.
Journal: Cancer research 20100901
Title: Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling.
Journal: Biochemical pharmacology 20100815
Title: Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy.
Journal: Cancer 20100815
Title: Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts.
Journal: Circulation research 20100806
Title: Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.
Journal: Breast cancer research and treatment 20100801
Title: Functional modulation of IGF-binding protein-3 expression in melanoma.
Journal: The Journal of investigative dermatology 20100801
Title: Pharmacotherapy of myelodysplastic syndromes.
Journal: Expert opinion on pharmacotherapy 20100801
Title: Therapy with azanucleosides for myelodysplastic syndromes.
Journal: Nature reviews. Clinical oncology 20100801
Title: Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100801
Title: Identification of novel methylation markers in hepatocellular carcinoma using a methylation array.
Journal: Journal of Korean medical science 20100801
Title: Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.
Journal: Molecular cancer therapeutics 20100801
Title: Fetal globin gene inducers: novel agents and new potential.
Journal: Annals of the New York Academy of Sciences 20100801
Title: [Study on promoter methylation status of E-cadherin gene in nasopharyngeal carcinoma cell lines].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20100801
Title: Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer.
Journal: Cancer research 20100715
Title: MAD2 downregulation in hypoxia is independent of promoter hypermethylation.
Journal: Cell cycle (Georgetown, Tex.) 20100715
Title: The functional significance of microRNA-145 in prostate cancer.
Journal: British journal of cancer 20100713
Title: In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.
Journal: Blood 20100708
Title: Rapid determination of AKAP12 promoter methylation levels in peripheral blood using methylation-sensitive high resolution melting (MS-HRM) analysis: application in colorectal cancer.
Journal: Clinica chimica acta; international journal of clinical chemistry 20100704
Title: Changes in chromatin structure and methylation of the human interleukin-1beta gene during monopoiesis.
Journal: Immunology 20100701
Title: Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells.
Journal: Pancreas 20100701
Title: Establishment and characterization of multi-drug resistant, prostate carcinoma-initiating stem-like cells from human prostate cancer cell lines 22RV1.
Journal: Molecular and cellular biochemistry 20100701
Title: Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene.
Journal: Journal of cellular physiology 20100701
Title: Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b.
Journal: Carcinogenesis 20100701
Title: The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells.
Journal: Leukemia research 20100701
Title: Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation.
Journal: British journal of haematology 20100701
Title: Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells.
Journal: The American journal of pathology 20100701
Title: DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae.
Journal: Cancer science 20100701
Title: Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy.
Journal: Molecular cancer research : MCR 20100701
Title: Screening for methylation-silenced genes in acute myeloid leukemia HL-60 cell line by a quantitative proteomic approach.
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100701
Title: Promoter hypomethylation contributes to the expression of MUC3A in cancer cells.
Journal: Biochemical and biophysical research communications 20100625
Title: Downregulation of WIF-1 by hypermethylation in astrocytomas.
Journal: Acta biochimica et biophysica Sinica 20100615
Title: Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.
Journal: Blood 20100610
Title: Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression.
Journal: Toxicology letters 20100602
Title: 5-Aza-2'-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1.
Journal: Medical oncology (Northwood, London, England) 20100601
Title: Induction of apoptosis of non-small cell lung cancer by a methylated oligonucleotide targeting survivin gene.
Journal: Cancer gene therapy 20100601
Title: Epigenetic therapy in myelodysplastic syndromes.
Journal: European journal of haematology 20100601
Title: Quantitative assessment of AKAP12 promoter methylation in colorectal cancer using methylation-sensitive high resolution melting: Correlation with Duke's stage.
Journal: Cancer biology & therapy 20100601
Title: Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells.
Journal: Cancer research 20100601
Title: Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.
Journal: Molecular cancer therapeutics 20100601
Title: Feasibility of therapy with hypomethylating agents in patients with renal insufficiency.
Journal: Clinical lymphoma, myeloma & leukemia 20100601
Title: Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells.
Journal: Anticancer research 20100601
Title: Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatoma.
Journal: World journal of gastroenterology 20100521
Title: [The relationship between the TSLC1 silencing and DNA methylation in human lung cancer cells].
Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100520
Title: Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene.
Journal: Experimental cell research 20100515
Title: FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma.
Journal: The British journal of dermatology 20100501
Title: Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells.
Journal: Cancer investigation 20100501
Title: Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2'-deoxycytidine.
Journal: Cancer immunology, immunotherapy : CII 20100501
Title: Neutrophilic eccrine hidradenitis associated with decitabine.
Journal: Leukemia research 20100501
Title: Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis.
Journal: Carcinogenesis 20100501
Title: Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation.
Journal: Genes, chromosomes & cancer 20100501
Title: Aberrant methylation impairs low density lipoprotein receptor-related protein 1B tumor suppressor function in gastric cancer.
Journal: Genes, chromosomes & cancer 20100501
Title: Epigenetically regulated clonal heritability of CTA expression profiles in human melanoma.
Journal: Journal of cellular physiology 20100501
Title: TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer.
Journal: Genes, chromosomes & cancer 20100501
Title: 5-Aza-2'-deoxycytidine treatment induces skeletal myogenic differentiation of mouse dental pulp stem cells.
Journal: Archives of oral biology 20100501
Title: Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
Journal: International journal of oncology 20100501
Title: [Epigenetic therapy in myelodysplastic syndromes (MDS). Treatment with DNA methyltransferase inhibitors].
Journal: Pharmazie in unserer Zeit 20100501
Title: Advances in the management of acute myeloid leukemia in older adult patients.
Journal: Oncology nursing forum 20100501
Title: S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth.
Journal: Molecular cancer therapeutics 20100501
Title: Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.
Journal: The Journal of biological chemistry 20100416
Title: Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines.
Journal: Toxicology letters 20100415
Title: Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.
Journal: Breast cancer research and treatment 20100401
Title: CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
Journal: Breast cancer research and treatment 20100401
Title: Effects of decitabine on the expression of selected endogenous control genes in human breast cancer cells.
Journal: Molecular and cellular probes 20100401
Title: Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401
Title: Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401
Title: Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells.
Journal: Toxicology letters 20100401
Title: Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas.
Journal: Neuropathology and applied neurobiology 20100401
Title: Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma.
Journal: International journal of oncology 20100401
Title: Identification of hypermethylated genes associated with cisplatin resistance in human cancers.
Journal: Cancer research 20100401
Title: Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.
Journal: Molecular cancer research : MCR 20100401
Title: Epigenetic changes in the myelodysplastic syndrome.
Journal: Hematology/oncology clinics of North America 20100401
Title: Practical recommendations for hypomethylating agent therapy of patients with myelodysplastic syndromes.
Journal: Hematology/oncology clinics of North America 20100401
Title: [No correlation between the sensitivity to 5-aza-dC and the global DNA methylation level in hepatocellular carcinoma cells].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100401
Title: Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
Journal: Journal of gastroenterology and hepatology 20100401
Title: Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2'-deoxycytidine in Neuro-2a cells.
Journal: Biochemical and biophysical research communications 20100326
Title: RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells.
Journal: Molecular biology reports 20100301
Title: IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.
Journal: Carcinogenesis 20100301
Title: 5-Aza-2'-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis.
Journal: Leukemia research 20100301
Title: Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi.
Journal: Immunology 20100301
Title: Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest?
Journal: Current opinion in hematology 20100301
Title: Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.
Journal: Laboratory investigation; a journal of technical methods and pathology 20100301
Title: DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target.
Journal: Cancer research 20100301
Title: Valproic acid in the complex therapy of malignant tumors.
Journal: Current drug targets 20100301
Title: Antineoplastic effects of decitabine, an inhibitor of DNA promoter methylation, in adrenocortical carcinoma cells.
Journal: Archives of surgery (Chicago, Ill. : 1960) 20100301
Title: Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor.
Journal: Leukemia research 20100201
Title: 5-azacitidine prolongs overall survival in patients with myelodysplastic syndrome--a systematic review and meta-analysis.
Journal: Haematologica 20100201
Title: Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100201
Title: Decitabine versus 5-azacitidine for the treatment of myelodysplastic syndrome: adjusted indirect meta-analysis.
Journal: Haematologica 20100201
Title: Resistance to 5-aza-2'-deoxycytidine in genic regions compared to non-genic repetitive sequences.
Journal: The Journal of reproduction and development 20100201
Title: Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201
Title: Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines.
Journal: Leukemia & lymphoma 20100201
Title: DNA methylation and its involvement in carboxylesterase 1A1 (CES1A1) gene expression.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100201
Title: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation.
Journal: The FEBS journal 20100201
Title: Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors.
Journal: Epigenomics 20100201
Title: Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.
Journal: Oncogene 20100128
Title: DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells.
Journal: Experimental cell research 20100115
Title: Efficient readout of posttranslational codes on the 50-residue tail of histone H3 by high-resolution MS/MS.
Journal: Analytical biochemistry 20100115
Title: DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection.
Journal: Analytical biochemistry 20100115
Title: Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene.
Journal: The Journal of biological chemistry 20100115
Title: SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Journal: Cancer research 20100115
Title: Frequent methylation of RASSF1A in synovial sarcoma and the anti-tumor effects of 5-aza-2'-deoxycytidine against synovial sarcoma cell lines.
Journal: Journal of cancer research and clinical oncology 20100101
Title: Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer.
Journal: Human pathology 20100101
Title: Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection.
Journal: Molecular reproduction and development 20100101
Title: Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100101
Title: Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation.
Journal: British journal of haematology 20100101
Title: 5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line.
Journal: Biochemical and biophysical research communications 20100101
Title: Decitabine in the treatment of myelodysplastic syndromes.
Journal: Expert review of anticancer therapy 20100101
Title: [Effect of 5-Aza-CdR on expression and methylation of E-cadherin gene in human colon carcinoma cells].
Journal: Chinese journal of cancer 20100101
Title: Decitabine.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101
Title: A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines.
Journal: PloS one 20100101
Title: Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.
Journal: BMC medical genomics 20100101
Title: Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.
Journal: Neuro-oncology 20100101
Title: BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas.
Journal: PloS one 20100101
Title: Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes.
Journal: Clinical advances in hematology & oncology : H&O 20100101
Title: NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer.
Journal: BMC cancer 20100101
Title: High-risk myelodysplastic syndromes: chemotherapy, transplantation, and beyond.
Journal: Current hematologic malignancy reports 20100101
Title: [Effect of 5-azadeoxycytidine and retinoic acid on expression of genomic imprinting in parthenogenetic mouse embryos].
Journal: Ontogenez 20100101
Title: Seladin-1 expression is regulated by promoter methylation in adrenal cancer.
Journal: BMC cancer 20100101
Title: Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.
Journal: PloS one 20100101
Title: Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma.
Journal: BMC cancer 20100101
Title: Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.
Journal: BMC cancer 20100101
Title: Active loss of DNA methylation in two-cell stage goat embryos.
Journal: The International journal of developmental biology 20100101
Title: Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.
Journal: BMC cancer 20100101
Title: BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines.
Journal: Cancer immunity 20100101
Title: Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.
Journal: PloS one 20100101
Title: DNA methylation and cancer.
Journal: Advances in genetics 20100101
Title: Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.
Journal: PloS one 20100101
Title: Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Cell line-dependent variability in HIV activation employing DNMT inhibitors.
Journal: Virology journal 20100101
Title: The effect of differentiating and apoptotic agents on notch signalling pathway in hepatoblastoma.
Journal: Hepato-gastroenterology 20100101
Title: TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
Journal: BMC cancer 20100101
Title: Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation.
Journal: PloS one 20100101
Title: Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells.
Journal: Reproductive biology and endocrinology : RB&E 20100101
Title: Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.
Journal: Biochemical and biophysical research communications 20091225
Title: Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.
Journal: Cancer 20091215
Title: High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors.
Journal: Cancer research 20091215
Title: Epigenetic modifications: new therapeutic targets in primary myelofibrosis.
Journal: Current stem cell research & therapy 20091201
Title: DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells.
Journal: Journal of cancer research and clinical oncology 20091201
Title: Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells.
Journal: Toxicology and applied pharmacology 20091201
Title: Preventing autoimmunity by regulating regulatory T-cell induction.
Journal: Journal of molecular medicine (Berlin, Germany) 20091201
Title: Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice.
Journal: Journal of molecular medicine (Berlin, Germany) 20091201
Title: Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20091201
Title: Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
Journal: Molecular cancer therapeutics 20091201
Title: Mechanism of DNA replication-dependent transcriptional activation of the acetylcholinesterase gene in the Ciona intestinalis embryo.
Journal: Development, growth & differentiation 20091201
Title: A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.
Journal: Cancer prevention research (Philadelphia, Pa.) 20091201
Title: Decitabine treatment of patients with higher-risk myelodysplastic syndromes.
Journal: Leukemia research 20091201
Title: Epigenetic silencing of CRABP2 and MX1 in head and neck tumors.
Journal: Neoplasia (New York, N.Y.) 20091201
Title: Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.
Journal: Neoplasia (New York, N.Y.) 20091201
Title: Methods in DNA methylation profiling.
Journal: Epigenomics 20091201
Title: LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer.
Journal: Oncogene 20091126
Title: Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells.
Journal: Lung cancer (Amsterdam, Netherlands) 20091101
Title: Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine.
Journal: Annals of hematology 20091101
Title: Non-intensive treatment with low-dose 5-aza-2'-deoxycytidine (DAC) prior to allogeneic blood SCT of older MDS/AML patients.
Journal: Bone marrow transplantation 20091101
Title: Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms.
Journal: Molecular pharmacology 20091101
Title: Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells.
Journal: Oncology reports 20091101
Title: Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications.
Journal: European journal of cancer (Oxford, England : 1990) 20091101
Title: DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes.
Journal: Arthritis and rheumatism 20091101
Title: Myelodysplastic syndromes: emerging therapies, survival, and alternative outcomes.
Journal: Managed care (Langhorne, Pa.) 20091101
Title: Alternative dosing schedules for methylation inhibitors in MDS treatment.
Journal: Managed care (Langhorne, Pa.) 20091101
Title: Myelodysplastic syndromes: health care management considerations.
Journal: Managed care (Langhorne, Pa.) 20091101
Title: Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.
Journal: Biochemical and biophysical research communications 20091016
Title: Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines.
Journal: Cancer research 20091015
Title: Alteration of transcriptional profile in human bronchial epithelial cells induced by cigarette smoke condensate.
Journal: Toxicology letters 20091008
Title: Epigenetic therapies move into new territory, but how exactly do they work?
Journal: Journal of the National Cancer Institute 20091007
Title: Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells.
Journal: The Journal of biological chemistry 20091002
Title: Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms.
Journal: Experimental hematology 20091001
Title: Methylation-associated silencing of S100A4 expression in human epidermal cancers.
Journal: Experimental dermatology 20091001
Title: Atypical presentations of Sweet's syndrome in patients with MDS/AML receiving combinations of hypomethylating agents with histone deacetylase inhibitors.
Journal: American journal of hematology 20091001
Title: Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents.
Journal: Cancer research 20091001
Title: Development of a novel output value for quantitative assessment in methylated DNA immunoprecipitation-CpG island microarray analysis.
Journal: DNA research : an international journal for rapid publication of reports on genes and genomes 20091001
Title: Fluorescence polarization combined capillary electrophoresis immunoassay for the sensitive detection of genomic DNA methylation.
Journal: Analytical chemistry 20091001
Title: Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax.
Journal: Neoplasia (New York, N.Y.) 20091001
Title: [Management of anemia and bone marrow hypoplasia in the treatment of myeloid leukemia].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20091001
Title: [Novel therapeutic agents for myelodysplastic syndrome].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001
Title: Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090915
Title: Case records of the Massachusetts General Hospital. Case 28-2009. A 68-year-old man with fatigue, cough, and peripheral-blood monocytosis.
Journal: The New England journal of medicine 20090910
Title: Decitabine-induced effusions.
Journal: Leukemia research 20090901
Title: Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia.
Journal: Leukemia 20090901
Title: Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.
Journal: International journal of cancer 20090901
Title: c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair.
Journal: Molecular and cellular neurosciences 20090901
Title: Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors.
Journal: The Prostate 20090901
Title: Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues.
Journal: Experimental hematology 20090901
Title: Decitabine combined with fractionated gemtuzumab ozogamicin therapy in patients with relapsed or refractory acute myeloid leukemia.
Journal: American journal of hematology 20090901
Title: Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
Title: A 64-year-old male with fever and persistent lung infiltrate.
Journal: Respiratory care 20090901
Title: [Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090901
Title: [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells].
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090901
Title: [Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901
Title: [Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090901
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Journal: Journal of cellular and molecular medicine 20090901
Title: Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing.
Journal: Molecular cell 20090828
Title: Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
Journal: Toxicology letters 20090825
Title: Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry.
Journal: Analytical biochemistry 20090815
Title: Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid.
Journal: Molecular and cellular endocrinology 20090813
Title: Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810
Title: Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.
Journal: Oncogene 20090806
Title: Promoter CpG methylation of oestrogen receptors in leukaemia.
Journal: Bioscience reports 20090801
Title: 5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801
Title: The property of methylated APC gene promotor and its influence on lung cancer cell line.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801
Title: iTRAQ-coupled 2-D LC-MS/MS analysis of protein profile associated with HBV-modulated DNA methylation.
Journal: Proteomics 20090801
Title: RUNX3 gene methylation in epithelial ovarian cancer tissues and ovarian cancer cell lines.
Journal: Omics : a journal of integrative biology 20090801
Title: Effects of 5-Aza-CdR on the proliferation of human breast cancer cell line MCF-7 and on the expression of Apaf-1 gene.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801
Title: Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.
Journal: Oncogene 20090730
Title: Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2.
Journal: The Journal of biological chemistry 20090717
Title: Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells.
Journal: International journal of cancer 20090715
Title: Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells.
Journal: Cancer research 20090715
Title: 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090715
Title: Treatment with demethylating agent, 5-aza-2'-deoxycytidine enhances therapeutic HPV DNA vaccine potency.
Journal: Vaccine 20090709
Title: Assessment of ATRX expression in patients with myelodysplastic syndromes treated with decitabine.
Journal: Leukemia research 20090701
Title: Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia.
Journal: Leukemia 20090701
Title: Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.
Journal: European journal of cancer (Oxford, England : 1990) 20090701
Title: Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas.
Journal: Laboratory investigation; a journal of technical methods and pathology 20090701
Title: Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090701
Title: Clinical roundtable monograph. Overall survival and maintenance of MDS patients.
Journal: Clinical advances in hematology & oncology : H&O 20090701
Title: Clinical roundtable monograph. Choosing an appropriate therapy for lower-risk MDS in the community setting.
Journal: Clinical advances in hematology & oncology : H&O 20090701
Title: [Effects of 5-aza-2'-deoxycytidine on the amount of exosomes and secreted immuno-associated proteins by hepatoma cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090701
Title: How I treat patients with myelodysplastic syndromes.
Journal: Blood 20090618
Title: Targeting DNA methylation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090615
Title: Synergy of 5-aza-2'-deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines.
Journal: Cancer letters 20090608
Title: Epigenetic control of differential expression of specific ERG isoforms in acute T-lymphoblastic leukemia.
Journal: Leukemia research 20090601
Title: Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome.
Journal: Bone marrow transplantation 20090601
Title: The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells.
Journal: Leukemia 20090601
Title: Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.
Journal: Carcinogenesis 20090601
Title: CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer.
Journal: International journal of oncology 20090601
Title: Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090601
Title: Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090601
Title: Chemical decomposition of 5-aza-2'-deoxycytidine (Decitabine): kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry.
Journal: Chemical research in toxicology 20090601
Title: Camptothecin-induced cell proliferation inhibition and apoptosis enhanced by DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine.
Journal: Biological & pharmaceutical bulletin 20090601
Title: DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.
Journal: Molecular cancer therapeutics 20090601
Title: Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells.
Journal: Anticancer research 20090601
Title: Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.
Journal: Molecular cancer research : MCR 20090601
Title: Use of epigenetic modification to induce FOXP3 expression in naïve T cells.
Journal: Transplantation proceedings 20090601
Title: Epigenetic regulation of HIV-1 latency by cytosine methylation.
Journal: PLoS pathogens 20090601
Title: [Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090601
Title: Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Journal: Biochemistry. Biokhimiia 20090601
Title: Clinical implications of gene expression profiling in myelodysplastic syndromes: recognition of ribosomal and translational gene dysregulation and development of predictive assays.
Journal: Best practice & research. Clinical haematology 20090601
Title: Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090515
Title: DNA methylation inhibits p53-mediated survivin repression.
Journal: Oncogene 20090514
Title: Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications.
Journal: Biochemical and biophysical research communications 20090508
Title: The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine.
Journal: Zygote (Cambridge, England) 20090501
Title: DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin.
Journal: Mutagenesis 20090501
Title: 5-AZA-2'-deoxycytidine (5-AZA-CdR) leads to down-regulation of Dnmt1o and gene expression in preimplantation mouse embryos.
Journal: Zygote (Cambridge, England) 20090501
Title: The comet assay: a sensitive method for detecting DNA damage in individual cells.
Journal: Methods (San Diego, Calif.) 20090501
Title: Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells.
Journal: Cancer biology & therapy 20090501
Title: Epigenetic reversal of acquired resistance to 5-fluorouracil treatment.
Journal: Molecular cancer therapeutics 20090501
Title: Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes.
Journal: Haematologica 20090501
Title: Epigenetic hierarchy governing Nestin expression.
Journal: Stem cells (Dayton, Ohio) 20090501
Title: Additive effects of 5-aza-2'-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20090501
Title: T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas.
Journal: Cancer science 20090501
Title: Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine.
Journal: Blood 20090430
Title: Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival.
Journal: British journal of cancer 20090407
Title: Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules.
Journal: Cancer immunology, immunotherapy : CII 20090401
Title: Demethylating agent 5-aza-2'-deoxycytidine activates HLA-G expression in human leukemia cell lines.
Journal: Leukemia research 20090401
Title: Decitabine is an effective treatment of idiopathic myelofibrosis.
Journal: British journal of haematology 20090401
Title: Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation.
Journal: Acta neuropathologica 20090401
Title: BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer.
Journal: Carcinogenesis 20090401
Title: Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study.
Journal: Proteomics 20090401
Title: Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status.
Journal: Molecular cancer therapeutics 20090401
Title: Durable clinical and cytogenetic remission in an elderly patient with relapsed acute myeloid leukemia treated with low-dose lenalidomide.
Journal: Leukemia & lymphoma 20090401
Title: [Effect of a methylation inhibitor 5-aza-2'-deoxycytidine on SHP-1 gene expression, proliferation and apoptosis in K562 cells].
Journal: Zhongguo shi yan xue ye xue za zhi 20090401
Title: LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Journal: Epigenetics 20090401
Title: Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells.
Journal: Archives of medical research 20090401
Title: Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy.
Journal: Blood 20090319
Title: Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity.
Journal: Cancer letters 20090318
Title: 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.
Journal: Biochemistry 20090317
Title: Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas.
Journal: Cancer research 20090315
Title: Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo.
Journal: British journal of cancer 20090310
Title: Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation.
Journal: The Kobe journal of medical sciences 20090310
Title: Complete cytogenetic remission after decitabine treatment in a patient with secondary AML harbouring high p15INK4b gene methylation and high global DNA methylation.
Journal: Annals of hematology 20090301
Title: Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.
Journal: Journal of neuro-oncology 20090301
Title: Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer.
Journal: Genes, chromosomes & cancer 20090301
Title: Differential CpG island methylation of murine adenine nucleotide translocase genes.
Journal: Biochimica et biophysica acta 20090301
Title: A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma.
Journal: International journal of radiation oncology, biology, physics 20090301
Title: Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090301
Title: GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling.
Journal: Anti-cancer drugs 20090301
Title: Optimal sequencing of treatments for patients with myelodysplastic syndromes.
Journal: Current opinion in hematology 20090301
Title: Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.
Journal: Life sciences 20090227
Title: The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae.
Journal: International journal of cancer 20090215
Title: Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
Journal: Biochemical and biophysical research communications 20090213
Title: Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation.
Journal: Blood 20090212
Title: Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine.
Journal: Cancer chemotherapy and pharmacology 20090201
Title: Progressive silencing of p14ARF in oesophageal adenocarcinoma.
Journal: Journal of cellular and molecular medicine 20090201
Title: Haemoglobin F modulation in childhood sickle cell disease.
Journal: British journal of haematology 20090201
Title: Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.
Journal: Carcinogenesis 20090201
Title: Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.
Journal: Cancer research 20090201
Title: Aberrant promoter methylation of SPARC in ovarian cancer.
Journal: Neoplasia (New York, N.Y.) 20090201
Title: Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy.
Journal: Molecular cancer research : MCR 20090201
Title: Androgen receptor CpG island methylation status in human leukemia cancer cells.
Journal: Cancer investigation 20090201
Title: Promoter CpG methylation in cancer cells contributes to the regulation of MUC4.
Journal: British journal of cancer 20090127
Title: Aberrant methylation of candidate tumor suppressor genes in neuroblastoma.
Journal: Cancer letters 20090118
Title: Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.
Journal: Oncogene 20090115
Title: Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines.
Journal: Blood 20090115
Title: Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration.
Journal: Cancer research 20090115
Title: DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma.
Journal: Gut 20090101
Title: Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma.
Journal: Genes, chromosomes & cancer 20090101
Title: Epigenetic silencing of LRRC3B in colorectal cancer.
Journal: Scandinavian journal of gastroenterology 20090101
Title: Comparative epigenomics of human and mouse mammary tumors.
Journal: Genes, chromosomes & cancer 20090101
Title: Epigenetic therapy of leukemia: An update.
Journal: The international journal of biochemistry & cell biology 20090101
Title: DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells.
Journal: Cancer science 20090101
Title: Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20090101
Title: Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells.
Journal: Cancer research 20090101
Title: [5-Aza-CdR regulates the expression of RASSF1A gene in human gastric cancer cell line and inhibits the growth of cells].
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090101
Title: Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line.
Journal: Urologia internationalis 20090101
Title: Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications.
Journal: PloS one 20090101
Title: The characterization of DNA methylation-mediated regulation of bovine placental lactogen and bovine prolactin-related protein-1 genes.
Journal: BMC molecular biology 20090101
Title: Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays.
Journal: PloS one 20090101
Title: Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells.
Journal: Anticancer research 20090101
Title: Quantitation of DNA methylation by melt curve analysis.
Journal: BMC cancer 20090101
Title: The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines.
Journal: World journal of surgical oncology 20090101
Title: 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.
Journal: Molecular cancer 20090101
Title: Activation of HLA-G expression by 5-aza-2 - deoxycytidine in malignant hematopoetic cells isolated from leukemia patients.
Journal: Neoplasma 20090101
Title: Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer.
Journal: Oncology research 20090101
Title: Real-time PCR analysis of genes encoding tumor antigens in esophageal tumors and a cancer vaccine.
Journal: Cancer immunity 20090101
Title: Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation.
Journal: Oncology research 20090101
Title: Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells.
Journal: PloS one 20090101
Title: Treatment of MDS: something old, something new, something borrowed..
Journal: Hematology. American Society of Hematology. Education Program 20090101
Title: Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity.
Journal: PloS one 20090101
Title: Management of myelodysplastic syndromes in the geriatric patient.
Journal: Current hematologic malignancy reports 20090101
Title: Myelodysplastic syndrome: An update on diagnosis and therapy.
Journal: Current hematologic malignancy reports 20090101
Title: Inhibition of DNA methyltransferase activity upregulates Fyn tyrosine kinase expression in Hut-78 T-lymphoma cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081201
Title: Alleviation of myelodysplastic syndrome-associated skin rush after treatment with decitabine.
Journal: European journal of haematology 20081201
Title: Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma.
Journal: Experimental hematology 20081201
Title: Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro.
Journal: Cancer biology & therapy 20081201
Title: Aberrant methylation of ADAMTS1 in non-small cell lung cancer.
Journal: Cancer genetics and cytogenetics 20081201
Title: Are new agents really making a difference in MDS?
Journal: Best practice & research. Clinical haematology 20081201
Title: [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20081201
Title: Recent advances in low- and intermediate-1-risk myelodysplastic syndrome: developing a consensus for optimal therapy.
Journal: Clinical advances in hematology & oncology : H&O 20081201
Title: Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A.
Journal: The Journal of biological chemistry 20081128
Title: PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells.
Journal: Biochemical and biophysical research communications 20081128
Title: p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia.
Journal: Cancer research 20081115
Title: Management of myelodysplastic syndromes: 2008 update.
Journal: Oncology (Williston Park, N.Y.) 20081115
Title: Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression.
Journal: Biochemical and biophysical research communications 20081107
Title: Demethylating agents in myeloid malignancies.
Journal: Current opinion in oncology 20081101
Title: The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas.
Journal: Oncology reports 20081101
Title: Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells.
Journal: Neoplasia (New York, N.Y.) 20081101
Title: DNA hypomethylation therapies and hemoglobin disorders. [An interview with Hassana Fathallah by H&O].
Journal: Clinical advances in hematology & oncology : H&O 20081101
Title: New agents for the treatment of AML recent study findings.
Journal: Clinical advances in hematology & oncology : H&O 20081101
Title: Future research directions for the treatment of AML.
Journal: Clinical advances in hematology & oncology : H&O 20081101
Title: [Myelodysplastic syndromes: therapeutic advances and promising future].
Journal: Medicina clinica 20081018
Title: Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.
Journal: International journal of cancer 20081015
Title: Promoter methylation of the bone morphogenetic protein-6 gene in association with adult T-cell leukemia.
Journal: International journal of cancer 20081015
Title: Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.
Journal: Blood 20081001
Title: Decitabine as 'bridge therapy' to a MUD transplant in relapsed AML postautologous stem cell transplantation.
Journal: American journal of hematology 20081001
Title: Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells.
Journal: International journal of oncology 20081001
Title: Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Journal: Cancer research 20081001
Title: [Pathogenesis of and therapeutic progress for myelodysplastic syndromes].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001
Title: Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR.
Journal: Breast cancer research and treatment 20080901
Title: Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells.
Journal: The Journal of clinical endocrinology and metabolism 20080901
Title: Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells.
Journal: International journal of cancer 20080901
Title: Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A.
Journal: Theriogenology 20080901
Title: LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer.
Journal: Cancer research 20080901
Title: Azacytidine causes complex DNA methylation responses in myeloid leukemia.
Journal: Molecular cancer therapeutics 20080901
Title: Cancer prevention: epigenetics steps up to the plate.
Journal: Cancer prevention research (Philadelphia, Pa.) 20080901
Title: [5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].
Journal: Zhonghua yi xue za zhi 20080819
Title: Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues.
Journal: Biochemical and biophysical research communications 20080815
Title: 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
Journal: Cancer letters 20080808
Title: ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor.
Journal: Journal of cancer research and clinical oncology 20080801
Title: Current status of epigenetic treatment in myelodysplastic syndromes.
Journal: Annals of hematology 20080801
Title: DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines.
Journal: International journal of cancer 20080801
Title: Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells.
Journal: International journal of cancer 20080801
Title: Epigenetic remodeling during arsenical-induced malignant transformation.
Journal: Carcinogenesis 20080801
Title: Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells.
Journal: International immunology 20080801
Title: 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis.
Journal: Cancer investigation 20080801
Title: Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells.
Journal: International journal of oncology 20080801
Title: Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma.
Journal: Oncology reports 20080801
Title: Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors.
Journal: Hepatology (Baltimore, Md.) 20080801
Title: New drugs in acute myeloid leukemia.
Journal: Seminars in oncology 20080801
Title: [Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro].
Journal: Zhongguo shi yan xue ye xue za zhi 20080801
Title: Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment.
Journal: Journal of endocrinological investigation 20080801
Title: [Hypomethylation of 5'CpG island of insulin-like growth factor binding protein-related protein 1 is associated with its overexpression in colorectal cancer].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20080801
Title: Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis.
Journal: Oncogene 20080724
Title: CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas.
Journal: Journal of the National Cancer Institute 20080702
Title: Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine.
Journal: International journal of cancer 20080701
Title: Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells.
Journal: Oncology reports 20080701
Title: Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines.
Journal: Cancer investigation 20080701
Title: Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines.
Journal: Science in China. Series C, Life sciences 20080701
Title: ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080615
Title: Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080615
Title: Induction of MHC class I-related chain B (MICB) by 5-aza-2'-deoxycytidine.
Journal: Biochemical and biophysical research communications 20080613
Title: SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.
Journal: British journal of cancer 20080603
Title: Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias.
Journal: Leukemia research 20080601
Title: The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.
Journal: International journal of cancer 20080601
Title: Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies.
Journal: Cancer 20080601
Title: Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease.
Journal: Placenta 20080601
Title: DNA methylation controls Foxp3 gene expression.
Journal: European journal of immunology 20080601
Title: Generalized granuloma annulare as an initial manifestation of chronic myelomonocytic leukemia: a report of 2 cases.
Journal: The American Journal of dermatopathology 20080601
Title: The human receptor tyrosine kinase Axl gene--promoter characterization and regulation of constitutive expression by Sp1, Sp3 and CpG methylation.
Journal: Bioscience reports 20080601
Title: Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin.
Journal: Urology 20080601
Title: DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.
Journal: Cancer cell 20080601
Title: Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro.
Journal: World journal of gastroenterology 20080521
Title: Effects of cellular differentiation, chromosomal integration and 5-aza-2'-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured cell lines.
Journal: Virology 20080510
Title: An epigenetic disorder may cause aberrant expression of aromatase gene in endometriotic stromal cells.
Journal: Fertility and sterility 20080501
Title: DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity.
Journal: Neurobiology of learning and memory 20080501
Title: DNA hypomethylation circuit of the mouse oocyte-specific histone H1foo gene in female germ cell lineage.
Journal: Biology of reproduction 20080501
Title: Epigenetic and HIF-1 regulation of stanniocalcin-2 expression in human cancer cells.
Journal: Experimental cell research 20080501
Title: Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma.
Journal: International journal of oncology 20080501
Title: Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.
Journal: Neoplasia (New York, N.Y.) 20080501
Title: Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.
Journal: Molecular cancer therapeutics 20080501
Title: TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells.
Journal: Molecular cancer research : MCR 20080501
Title: Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol.
Journal: Environment international 20080401
Title: Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
Journal: Cancer chemotherapy and pharmacology 20080401
Title: Efficacy of decitabine in the treatment of patients with chronic myelomonocytic leukemia (CMML).
Journal: Leukemia research 20080401
Title: 5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene.
Journal: British journal of pharmacology 20080401
Title: Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts.
Journal: Experimental eye research 20080401
Title: Clinical effectiveness of decitabine in severe sickle cell disease.
Journal: British journal of haematology 20080401
Title: Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo.
Journal: Journal of cell science 20080401
Title: Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers.
Journal: Cancer research 20080401
Title: DNA methyltransferase inhibitors: class effect or unique agents?
Journal: Leukemia & lymphoma 20080401
Title: Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine.
Journal: Leukemia & lymphoma 20080401
Title: Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.
Journal: Stem cells and development 20080401
Title: [Analysis of in vitro anti-leukemia effect of 5-aza-2'-deoxycitydine].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080401
Title: The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage.
Journal: BMB reports 20080331
Title: The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
Journal: Oncogene 20080327
Title: 5-Aza-2'-deoxycytidine increases the expression of anti-angiogenic vascular endothelial growth factor 189b variant in human lung microvascular endothelial cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080301
Title: DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.
Journal: Human molecular genetics 20080301
Title: Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.
Journal: Neoplasia (New York, N.Y.) 20080301
Title: [Myelodysplastic syndrome].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20080301
Title: SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome.
Journal: PLoS genetics 20080301
Title: Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells.
Journal: Biochemical pharmacology 20080215
Title: Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia.
Journal: Blood 20080215
Title: Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215
Title: Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells.
Journal: FEBS letters 20080206
Title: An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment.
Journal: The Journal of biological chemistry 20080201
Title: Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination.
Journal: DNA repair 20080201
Title: DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines.
Journal: The Prostate 20080201
Title: Drugs affecting prelamin A processing: effects on heterochromatin organization.
Journal: Experimental cell research 20080201
Title: [Methylation of PTPRG gene and its regulation in gastric cancer].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080201
Title: Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB.
Journal: World journal of gastroenterology 20080128
Title: Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL.
Journal: Oncogene 20080117
Title: Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes.
Journal: Oncogene 20080110
Title: Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.
Journal: Brain research 20080110
Title: PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells.
Journal: Leukemia research 20080101
Title: Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer.
Journal: The Journal of pathology 20080101
Title: Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.
Journal: American journal of physiology. Renal physiology 20080101
Title: DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.
Journal: Molecular and cellular biology 20080101
Title: CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding.
Journal: Nucleic acids research 20080101
Title: Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription.
Journal: Nature cell biology 20080101
Title: Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.
Journal: Cancer research 20080101
Title: Myelodysplastic syndromes: introduction.
Journal: Seminars in hematology 20080101
Title: DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes.
Journal: Seminars in hematology 20080101
Title: Pharmacogenomics and therapeutics of hemoglobinopathies.
Journal: Hemoglobin 20080101
Title: Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine.
Journal: The international journal of biochemistry & cell biology 20080101
Title: Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer.
Journal: BMC cancer 20080101
Title: Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma.
Journal: Pathobiology : journal of immunopathology, molecular and cellular biology 20080101
Title: HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.
Journal: PloS one 20080101
Title: Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy.
Journal: BMC gastroenterology 20080101
Title: DNA methylation: its role in cancer development and therapy.
Journal: Current problems in cancer 20080101
Title: Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia.
Journal: Oncology research 20080101
Title: Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression.
Journal: BMC cancer 20080101
Title: [Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell].
Journal: Zhonghua yi xue za zhi 20071225
Title: PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Journal: Oncogene 20071213
Title: Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention.
Journal: Annals of the rheumatic diseases 20071201
Title: Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma.
Journal: Leukemia 20071201
Title: Downregulation of microRNAs-143 and -145 in B-cell malignancies.
Journal: Cancer science 20071201
Title: Downregulation of several fibulin genes in prostate cancer.
Journal: The Prostate 20071201
Title: Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor.
Journal: The Prostate 20071201
Title: Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer.
Journal: World journal of gastroenterology 20071121
Title: Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours.
Journal: British journal of cancer 20071119
Title: Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis.
Journal: American journal of hematology 20071101
Title: p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma.
Journal: Journal of clinical pathology 20071101
Title: Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20071101
Title: The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.
Journal: The American journal of pathology 20071101
Title: Regulation of the CLDN3 gene in ovarian cancer cells.
Journal: Cancer biology & therapy 20071101
Title: Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors.
Journal: Neoplasia (New York, N.Y.) 20071101
Title: Evaluating new treatment options for MDS.
Journal: Clinical advances in hematology & oncology : H&O 20071101
Title: [Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071101
Title: ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations.
Journal: FEBS letters 20071030
Title: Combining epigenetic and cytotoxic therapy in the treatment of solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010
Title: Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010
Title: Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.
Journal: Oncogene 20071004
Title: Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation.
Journal: Oral oncology 20071001
Title: Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis.
Journal: Leukemia research 20071001
Title: Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy.
Journal: Journal of molecular medicine (Berlin, Germany) 20071001
Title: Promoter methylation regulates estrogen receptor 2 in human endometrium and endometriosis.
Journal: Biology of reproduction 20071001
Title: Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071001
Title: Gene induction and apoptosis in human hepatocellular carci-noma cells SMMC-7721 exposed to 5-aza-2'-deoxycytidine.
Journal: Chinese medical journal 20070920
Title: Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma.
Journal: The Prostate 20070915
Title: Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting.
Journal: Leukemia research 20070901
Title: Adverse effects of 5-aza-2'-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation.
Journal: The Journal of pharmacology and experimental therapeutics 20070901
Title: Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20070901
Title: Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901
Title: Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.
Journal: British journal of haematology 20070901
Title: Decitabine up-regulates S100A2 expression and synergizes with IFN-gamma to kill uveal melanoma cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070901
Title: The use of hypomethylating agents in the treatment of hematologic malignancies.
Journal: Leukemia & lymphoma 20070901
Title: Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation.
Journal: AAPS PharmSciTech 20070901
Title: SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.
Journal: Oncogene 20070816
Title: Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer.
Journal: Cancer research 20070815
Title: Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining repair of DNA double-strand breaks in human oral cancer cells.
Journal: Biochemistry 20070807
Title: Frequent inactivation of SPARC by promoter hypermethylation in colon cancers.
Journal: International journal of cancer 20070801
Title: Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells.
Journal: International journal of cancer 20070801
Title: Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070801
Title: Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis.
Journal: The Journal of clinical endocrinology and metabolism 20070801
Title: Preferential cytogenetic response to continuous intravenous low-dose decitabine (DAC) administration in myelodysplastic syndrome with monosomy 7.
Journal: Blood 20070801
Title: Decitabine dosage in myelodysplastic syndromes.
Journal: Blood 20070801
Title: The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma.
Journal: Cancer genetics and cytogenetics 20070801
Title: Decitabine and its role in the treatment of hematopoietic malignancies.
Journal: Leukemia & lymphoma 20070801
Title: Monocytic skin nodules in chronic myelomonocytic leukemia: clinical response to decitabine therapy.
Journal: Leukemia & lymphoma 20070801
Title: High expressions of neuronatin isoforms in favorable neuroblastoma.
Journal: Journal of pediatric hematology/oncology 20070801
Title: Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells.
Journal: Biochemical and biophysical research communications 20070727
Title: Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.
Journal: Oncogene 20070726
Title: [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor].
Journal: Zhonghua yi xue za zhi 20070724
Title: Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers.
Journal: Oncogene 20070719
Title: Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma.
Journal: British journal of cancer 20070716
Title: Silencing of tissue factor pathway inhibitor-2 gene in malignant melanomas.
Journal: International journal of cancer 20070715
Title: Effect of cytarabine and decitabine in combination in human leukemic cell lines.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070715
Title: Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter.
Journal: Oncogene 20070705
Title: Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.
Journal: Breast cancer research and treatment 20070701
Title: Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701
Title: The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.
Journal: Laboratory investigation; a journal of technical methods and pathology 20070701
Title: Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Journal: Genes, chromosomes & cancer 20070701
Title: Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
Journal: Cancer research 20070701
Title: Effects of chromatin-modifying agents on CD34+ cells from patients with idiopathic myelofibrosis.
Journal: Cancer research 20070701
Title: Use of hypomethylating agents in myelodysplastic syndromes.
Journal: Clinical advances in hematology & oncology : H&O 20070701
Title: Effects of 5-aza-2'-deoxycytidine on the gene expression profile during embryogenesis of the Ascidian ciona intestinalis: a microarray analysis.
Journal: Zoological science 20070701
Title: Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer.
Journal: Cancer letters 20070618
Title: Epigenetic and functional analysis of IGFBP3 and IGFBPrP1 in cellular immortalization.
Journal: Biochemical and biophysical research communications 20070608
Title: A selective activity of DNMTi decitabine on AML1ETO positive cells?
Journal: Leukemia research 20070601
Title: DNA methylation regulates tissue-specific expression of Shank3.
Journal: Journal of neurochemistry 20070601
Title: Overlapping roles of the methylated DNA-binding protein MBD1 and polycomb group proteins in transcriptional repression of HOXA genes and heterochromatin foci formation.
Journal: The Journal of biological chemistry 20070601
Title: Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells.
Journal: The Journal of pathology 20070601
Title: Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070601
Title: Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth.
Journal: Cancer research 20070601
Title: [Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20070601
Title: Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20070601
Title: DNA methyltransferases as targets for cancer therapy.
Journal: Drugs of today (Barcelona, Spain : 1998) 20070601
Title: Re-expression of RASSF1A by 5-Aza-CdR induced demethylation of the promoter region in human biliary tract carcinoma cells.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070601
Title: Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors.
Journal: Cancer letters 20070518
Title: Genetic redundancy in human cervical carcinoma cells: identification of cells with 'normal' properties.
Journal: International journal of cancer 20070515
Title: MAGE-A9 mRNA and protein expression in bladder cancer.
Journal: International journal of cancer 20070515
Title: Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma.
Journal: Cancer 20070515
Title: Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma.
Journal: Cancer research 20070515
Title: Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
Journal: Annals of surgical oncology 20070501
Title: The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.
Journal: Blood 20070501
Title: The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.
Journal: FEMS microbiology letters 20070501
Title: Discovery of epigenetically silenced genes in acute myeloid leukemias.
Journal: Leukemia 20070501
Title: Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression.
Journal: The Journal of pathology 20070501
Title: Aberrant DNA methylation of the Src kinase Hck, but not of Lyn, in Philadelphia chromosome negative acute lymphocytic leukemia.
Journal: Leukemia 20070501
Title: Down-regulation of IL-7Ralpha expression in human T cells via DNA methylation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070501
Title: Methylation of Ras association domain family protein 1, isoform A correlated with proliferation and drug resistance in hepatocellular carcinoma cell line SMMC-7721.
Journal: Journal of gastroenterology and hepatology 20070501
Title: LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Journal: Cancer research 20070501
Title: Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma.
Journal: Hepatology (Baltimore, Md.) 20070501
Title: Identification of epigenetically silenced genes in tumor endothelial cells.
Journal: Cancer research 20070501
Title: Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia.
Journal: Blood 20070415
Title: Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential.
Journal: Blood 20070415
Title: High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene.
Journal: Cancer genetics and cytogenetics 20070415
Title: Strategies for achieving transfusion independence in myelodysplastic syndromes.
Journal: European journal of oncology nursing : the official journal of European Oncology Nursing Society 20070401
Title: Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines.
Journal: Leukemia research 20070401
Title: Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites.
Journal: Histochemistry and cell biology 20070401
Title: Transcriptional reactivation of murine cytomegalovirus ie gene expression by 5-aza-2'-deoxycytidine and trichostatin A in latently infected cells despite lack of methylation of the major immediate-early promoter.
Journal: The Journal of general virology 20070401
Title: 5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070401
Title: Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas.
Journal: Haematologica 20070401
Title: Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol.
Journal: The Journal of biological chemistry 20070323
Title: Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience.
Journal: Cancer 20070315
Title: Covalent modification of DNA regulates memory formation.
Journal: Neuron 20070315
Title: DNA methylation as a therapeutic target in cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070315
Title: 5-AZA-2'-deoxycytidine in cancer immunotherapy: a mouse to man story.
Journal: Cancer research 20070315
Title: Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir.
Journal: Cancer letters 20070308
Title: DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes.
Journal: Molecular pharmacology 20070301
Title: Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer.
Journal: The Journal of pathology 20070301
Title: Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.
Journal: Cancer 20070301
Title: Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method.
Journal: Nucleic acids research 20070301
Title: Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer.
Journal: Cancer science 20070301
Title: Myelodysplasia: the good, the fair and the ugly.
Journal: Best practice & research. Clinical haematology 20070301
Title: Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20070301
Title: Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20070301
Title: Igf-2r expression regulated by epigenetic modification and the locus of gene imprinting disrupted in cloned cattle.
Journal: Gene 20070215
Title: Activity of decitabine, a hypomethylating agent, in chronic myelomonocytic leukemia.
Journal: Cancer 20070215
Title: Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue.
Journal: Cancer letters 20070208
Title: Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis.
Journal: Cell death and differentiation 20070201
Title: Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells.
Journal: Carcinogenesis 20070201
Title: Decitabine--bedside to bench.
Journal: Critical reviews in oncology/hematology 20070201
Title: Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation.
Journal: International journal of oncology 20070201
Title: Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene.
Journal: Nucleic acids research 20070201
Title: Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin.
Journal: Cancer research 20070201
Title: Recent experience with decitabine in MDS.
Journal: Clinical advances in hematology & oncology : H&O 20070201
Title: Downregulation of RUNX3 and TES by hypermethylation in glioblastoma.
Journal: Oncogene 20070125
Title: Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome.
Journal: Cancer 20070115
Title: 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation.
Journal: Oncogene 20070104
Title: Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia.
Journal: Blood 20070101
Title: Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis.
Journal: Molecular endocrinology (Baltimore, Md.) 20070101
Title: Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.
Journal: International journal of cancer 20070101
Title: High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array.
Journal: Human genetics 20070101
Title: Efficacy of DNA hypomethylating capacities of 5-aza-2'-deoxycytidine and its alpha anomer.
Journal: Pharmacological research 20070101
Title: Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer.
Journal: Oncology reports 20070101
Title: The role of decitabine in the treatment of myelodysplastic syndromes.
Journal: Expert opinion on pharmacotherapy 20070101
Title: Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070101
Title: Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment.
Journal: Cancer research 20070101
Title: [Role of epigenetics in the carcinogenesis of head and neck carcinomas - possible new targeted therapy?].
Journal: Laryngo- rhino- otologie 20070101
Title: Identification of candidate methylation-responsive genes in ovarian cancer.
Journal: Molecular cancer 20070101
Title: [Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070101
Title: Risk-based management of myelodysplastic syndrome.
Journal: Oncology (Williston Park, N.Y.) 20070101
Title: DNA methyltransferase inhibitors for cancer therapy.
Journal: Cancer journal (Sudbury, Mass.) 20070101
Title: Utilization of chromatin remodeling agents for lung cancer therapy.
Journal: Cancer journal (Sudbury, Mass.) 20070101
Title: Methylation-mediated silencing of genes is not altered by selenium treatment of prostate cancer cells.
Journal: Anticancer research 20070101
Title: New drugs: paliperidone, dasatinib, and decitabine.
Journal: Journal of the American Pharmacists Association : JAPhA 20070101
Title: Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.
Journal: BMC genomics 20070101
Title: Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2.
Journal: Biochimica et biophysica acta 20070101
Title: Decitabine and sickle cell disease: molecular therapy for a molecular disease.
Journal: Pediatric hematology and oncology 20070101
Title: DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote.
Journal: The International journal of developmental biology 20070101
Title: Modulation of HLA-G expression.
Journal: Neoplasma 20070101
Title: The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines.
Journal: Nucleosides, nucleotides & nucleic acids 20070101
Title: A role for DNA methylation in regulating the growth suppressor PMEPA1 gene in prostate cancer.
Journal: Epigenetics 20070101
Title: 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer).
Journal: Biochemical and biophysical research communications 20061215
Title: Low-dose decitabine and high-risk MDS.
Journal: Blood 20061215
Title: Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies.
Journal: Leukemia research 20061201
Title: Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression.
Journal: Journal of leukocyte biology 20061201
Title: DNA methylation-dependent silencing of CST6 in human breast cancer cell lines.
Journal: Laboratory investigation; a journal of technical methods and pathology 20061201
Title: Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.
Journal: Gastroenterology 20061201
Title: Epigenetic silencing of novel tumor suppressors in malignant melanoma.
Journal: Cancer research 20061201
Title: A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
Journal: PLoS medicine 20061201
Title: Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumors.
Journal: Endocrine 20061201
Title: [Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201
Title: [Demethylation of estrogen receptor gene and its re-expression in estrogen receptor-negative breast].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201
Title: Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction.
Journal: International journal of cancer 20061115
Title: Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.
Journal: Blood 20061115
Title: The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation.
Journal: International journal of cancer 20061115
Title: Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061115
Title: Decitabine (Dacogen) for myelodysplastic syndromes.
Journal: The Medical letter on drugs and therapeutics 20061106
Title: Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2'-deoxycytidine (decitabine) on human breast carcinoma cells.
Journal: Cancer chemotherapy and pharmacology 20061101
Title: Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells.
Journal: Toxicology and applied pharmacology 20061101
Title: Epigenetic regulation of human trophoblastic cell migration and invasion.
Journal: Endocrinology 20061101
Title: Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
Journal: Journal of molecular medicine (Berlin, Germany) 20061101
Title: Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies.
Journal: American journal of human genetics 20061101
Title: Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
Journal: Cancer research 20061101
Title: Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression.
Journal: Cancer research 20061101
Title: Decitabine.
Journal: Nature reviews. Drug discovery 20061101
Title: [Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer].
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20061101
Title: Targeting the epigenome for the treatment of thoracic malignancies.
Journal: Thoracic surgery clinics 20061101
Title: Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer.
Journal: Cancer biology & therapy 20061101
Title: Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression.
Journal: Molecules and cells 20061031
Title: [Expression of S100A2 in secondarily radioresistant pancreatic cancer cells and significance thereof].
Journal: Zhonghua yi xue za zhi 20061031
Title: Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation.
Journal: Cancer letters 20061028
Title: Epigenetic cancer therapy makes headway.
Journal: Journal of the National Cancer Institute 20061018
Title: DNA mismatch repair as an effector for promoting phorbol ester-induced apoptotic DNA damage and cell killing: implications in tumor promotion.
Journal: International journal of cancer 20061015
Title: Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines.
Journal: International journal of cancer 20061001
Title: Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells.
Journal: Blood 20061001
Title: PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
Journal: Annals of hematology 20061001
Title: An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.
Journal: Cancer research 20061001
Title: Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061001
Title: [SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20061001
Title: Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues.
Journal: World journal of gastroenterology 20060921
Title: High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma.
Journal: Journal of clinical pathology 20060901
Title: Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.
Journal: Cancer science 20060901
Title: Regulation of DNA methylation on the expression of the FHIT gene contributes to cervical carcinoma cell tumorigenesis.
Journal: Oncology reports 20060901
Title: Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma.
Journal: Leukemia 20060901
Title: Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.
Journal: Experimental hematology 20060901
Title: Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20060901
Title: The genomics of new drugs in sickle cell disease.
Journal: Pharmacogenomics 20060901
Title: 5-Aza-2'-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8.
Journal: Oncogene 20060824
Title: Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation.
Journal: Oncogene 20060810
Title: Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060810
Title: Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing.
Journal: FEBS letters 20060807
Title: Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.
Journal: Leukemia research 20060801
Title: p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.
Journal: Journal of cellular biochemistry 20060801
Title: Epigenetic inactivation of the dioxin-responsive cytochrome P4501A1 gene in human prostate cancer.
Journal: Cancer research 20060801
Title: Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.
Journal: Cancer research 20060801
Title: Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
Title: Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer.
Journal: Oncogene 20060706
Title: The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells.
Journal: Human reproduction (Oxford, England) 20060701
Title: Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine.
Journal: American journal of hematology 20060701
Title: RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer.
Journal: Cancer research 20060701
Title: Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.
Journal: Cancer research 20060701
Title: Estrogen receptor-alpha methylation predicts melanoma progression.
Journal: Cancer research 20060701
Title: Methylation of neutral endopeptidase 24.11 promoter in rat hepatocellular carcinoma.
Journal: Cancer science 20060701
Title: Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes.
Journal: Cancer research 20060615
Title: GnT-V expression and metastatic phenotypes in macrophage-melanoma fusion hybrids is down-regulated by 5-Aza-dC: evidence for methylation sensitive, extragenic regulation of GnT-V transcription.
Journal: Gene 20060607
Title: Sequential gene expression changes in cancer cell lines after treatment with the demethylation agent 5-Aza-2'-deoxycytidine.
Journal: Cancer 20060601
Title: Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation.
Journal: Alcoholism, clinical and experimental research 20060601
Title: Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells.
Journal: Cancer cell 20060601
Title: Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer.
Journal: Biological chemistry 20060601
Title: The epigenetic basis for the aberrant expression of kallikreins in human cancers.
Journal: Biological chemistry 20060601
Title: [Disfigurement of p16INK4A gene expression in development of ovarian cancer and the mechanism].
Journal: Zhonghua fu chan ke za zhi 20060601
Title: Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression?
Journal: Virology 20060525
Title: Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.
Journal: Oncogene 20060518
Title: Identification of novel target genes by an epigenetic reactivation screen of renal cancer.
Journal: Cancer research 20060515
Title: DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia.
Journal: Cancer research 20060515
Title: Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells.
Journal: Oncogene 20060511
Title: Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.
Journal: Oncogene 20060511
Title: The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.
Journal: Carcinogenesis 20060501
Title: Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease.
Journal: American journal of human genetics 20060501
Title: Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.
Journal: Molecular and cellular biology 20060501
Title: Epigenetic inactivation of Betaig-h3 gene in human cancer cells.
Journal: Cancer research 20060501
Title: Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells.
Journal: Molecular cancer research : MCR 20060501
Title: [Transcription regulation of 5-Aza-2'-deoxycytidine on maspin gene demethylation in RKO human colorectal cell line].
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20060501
Title: New strategies in chronic myeloid leukemia.
Journal: International journal of hematology 20060501
Title: Review: recent clinical trials in epigenetic therapy.
Journal: Reviews on recent clinical trials 20060501
Title: Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b.
Journal: Oncogene 20060420
Title: Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study.
Journal: Cancer 20060415
Title: Drug therapy for myelodysplastic syndrome: building evidence for action.
Journal: Cancer 20060415
Title: Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients.
Journal: Cancer 20060415
Title: Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2.
Journal: Oncogene 20060406
Title: Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications.
Journal: Journal of cellular physiology 20060401
Title: Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Journal: Cell death and differentiation 20060401
Title: A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons.
Journal: Cancer research 20060401
Title: Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.
Journal: Cancer research 20060401
Title: PGP9.5 methylation in diffuse-type gastric cancer.
Journal: Cancer research 20060401
Title: Gene promoter hypermethylation in mouse lung tumors.
Journal: Molecular cancer research : MCR 20060401
Title: Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060401
Title: Epigenetic processes play a major role in B-cell-specific gene silencing in classical Hodgkin lymphoma.
Journal: Blood 20060315
Title: Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060315
Title: Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.
Journal: Biochemical and biophysical research communications 20060310
Title: Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines.
Journal: Biochemical and biophysical research communications 20060310
Title: Treatment of myelodysplastic syndrome with a DNA methyltransferase inhibitor: lack of evidence for induction of chromosomal instability.
Journal: Leukemia research 20060301
Title: Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing.
Journal: Leukemia research 20060301
Title: Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS.
Journal: American journal of physiology. Endocrinology and metabolism 20060301
Title: RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer.
Journal: Cancer biology & therapy 20060301
Title: Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway.
Journal: Cancer biology & therapy 20060301
Title: Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.
Journal: Cancer research 20060301
Title: Effect of methylation-associated silencing of the death-associated protein kinase gene on nasopharyngeal carcinoma.
Journal: Anti-cancer drugs 20060301
Title: Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060301
Title: Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis.
Journal: Experimental hematology 20060301
Title: Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood.
Journal: Oncogene 20060216
Title: Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation.
Journal: Oncogene 20060216
Title: PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060215
Title: Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas.
Journal: Oncogene 20060209
Title: Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer.
Journal: The Prostate 20060201
Title: Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer.
Journal: International journal of oncology 20060201
Title: A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells.
Journal: International journal of oncology 20060201
Title: Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents.
Journal: Experimental hematology 20060201
Title: Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R.
Journal: The Journal of endocrinology 20060201
Title: Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201
Title: CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia.
Journal: Cancer research 20060115
Title: De novo induction of a cancer/testis antigen by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model.
Journal: Cancer research 20060115
Title: Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060115
Title: 5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation.
Journal: Leukemia research 20060101
Title: Effects of 5-aza-2'-deoxycytidine on proliferation, differentiation and p15/INK4b regulation of human hematopoietic progenitor cells.
Journal: Leukemia 20060101
Title: Aberrant promoter methylation of EDNRB in lung cancer in Taiwan.
Journal: Oncology reports 20060101
Title: Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.
Journal: Cancer science 20060101
Title: Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer.
Journal: Cancer research 20060101
Title: Current therapy of sickle cell disease.
Journal: Haematologica 20060101
Title: Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060101
Title: Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2'-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method.
Journal: Rapid communications in mass spectrometry : RCM 20060101
Title: Decitabine: in myelodysplastic syndromes.
Journal: Drugs 20060101
Title: Decitabine in myelodysplastic syndromes: viewpoints.
Journal: Drugs 20060101
Title: Methylation mediated silencing of TMS1/ASC gene in prostate cancer.
Journal: Molecular cancer 20060101
Title: Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nucleoside analogues.
Journal: Nucleosides, nucleotides & nucleic acids 20060101
Title: Induction of fetal hemoglobin in the treatment of sickle cell disease.
Journal: Hematology. American Society of Hematology. Education Program 20060101
Title: New treatment for rare bone marrow condition.
Journal: FDA consumer 20060101
Title: Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma.
Journal: Oncology 20060101
Title: Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.
Journal: Oncology research 20060101
Title: The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors.
Journal: Oncology 20060101
Title: 5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells.
Journal: Cancer letters 20051218
Title: Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction.
Journal: Cancer research 20051215
Title: Decitabine activates specific caspases downstream of p73 in myeloid leukemia.
Journal: Annals of hematology 20051201
Title: An epigenetic approach to the treatment of advanced MDS; the experience with the DNA demethylating agent 5-aza-2'-deoxycytidine (decitabine) in 177 patients.
Journal: Annals of hematology 20051201
Title: Decitabine: a historical review of the development of an epigenetic drug.
Journal: Annals of hematology 20051201
Title: Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts.
Journal: Annals of hematology 20051201
Title: Clinical experience with decitabine in North American patients with myelodysplastic syndrome.
Journal: Annals of hematology 20051201
Title: In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies.
Journal: Annals of hematology 20051201
Title: Quantification of outpatient management and hospitalization of patients with high-risk myelodysplastic syndrome treated with low-dose decitabine.
Journal: Annals of hematology 20051201
Title: The hematopathological basis for studying effects of the demethylating agent 5-aza-2'-deoxycytidine (decitabine) in myelodysplasia.
Journal: Annals of hematology 20051201
Title: BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy.
Journal: Cancer research 20051201
Title: Methylation inhibitor therapy in the treatment of myelodysplastic syndrome.
Journal: Nature clinical practice. Oncology 20051201
Title: Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection.
Journal: Nature clinical practice. Oncology 20051201
Title: Inhibitors of DNA methylation: beyond myelodysplastic syndromes.
Journal: Nature clinical practice. Oncology 20051201
Title: DNA methylation and gene silencing in cancer.
Journal: Nature clinical practice. Oncology 20051201
Title: [The synergistic inhibitory effect of 5-aza-2-deoxycytidine and Tamoxifen on estrogen receptor alpha negative breast cancer cell lines in vitro].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20051201
Title: Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies.
Journal: Carcinogenesis 20051101
Title: Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
Journal: Cancer chemotherapy and pharmacology 20051101
Title: The epigenome as a molecular marker and target.
Journal: Cancer 20051101
Title: The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells.
Journal: Molecular cancer therapeutics 20051101
Title: New agents in the treatment of MDS.
Journal: Clinical advances in hematology & oncology : H&O 20051101
Title: Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051015
Title: Differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions.
Journal: The Journal of biological chemistry 20051014
Title: Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines.
Journal: Gynecologic oncology 20051001
Title: The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents.
Journal: International journal of oncology 20051001
Title: 5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines.
Journal: Oncology reports 20051001
Title: 5-azacytidine and decitabine monotherapies of myelodysplastic disorders.
Journal: The Annals of pharmacotherapy 20051001
Title: Trapped in action: direct visualization of DNA methyltransferase activity in living cells.
Journal: Nature methods 20051001
Title: Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.
Journal: British journal of haematology 20051001
Title: Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051001
Title: Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy.
Journal: Cancer research 20051001
Title: The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer.
Journal: Cancer research 20051001
Title: Epigenetic drugs: a longstanding story.
Journal: Seminars in oncology 20051001
Title: Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine).
Journal: Seminars in oncology 20051001
Title: Clinical development of decitabine as a prototype for an epigenetic drug program.
Journal: Seminars in oncology 20051001
Title: Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents.
Journal: Seminars in oncology 20051001
Title: [Inhibitory effect of 5-Aza-2'-deoxycytidine on human nasopharyngeal carcinoma xenograft in nude mice].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20051001
Title: Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.
Journal: Molecular cancer therapeutics 20051001
Title: Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Journal: Molecular cancer therapeutics 20051001
Title: Epigenetic therapy with decitabine for myelodysplasia and leukemia.
Journal: Future oncology (London, England) 20051001
Title: The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.
Journal: Cancer research 20050915
Title: GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050915
Title: The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050915
Title: Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP).
Journal: Molecular endocrinology (Baltimore, Md.) 20050901
Title: Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach.
Journal: Oncogene 20050901
Title: Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes.
Journal: Cancer research 20050901
Title: DNA methylation in the treatment of hematologic malignancies.
Journal: Clinical advances in hematology & oncology : H&O 20050901
Title: CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines.
Journal: Thrombosis and haemostasis 20050901
Title: Hypermethylation of the RUNX3 gene in hepatocellular carcinoma.
Journal: Experimental & molecular medicine 20050831
Title: Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.
Journal: Circulation 20050830
Title: Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome.
Journal: Cancer research 20050815
Title: P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050815
Title: Granulocyte-macrophage colony-stimulating factor induces de novo methylation of the p15 CpG island in hematopoietic cells.
Journal: Cytokine 20050807
Title: Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.
Journal: Leukemia 20050801
Title: Conventional and new treatment options for myelofibrosis with myeloid metaplasia.
Journal: Seminars in oncology 20050801
Title: Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta.
Journal: Oncogene 20050728
Title: Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene.
Journal: Biochimica et biophysica acta 20050725
Title: Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20050701
Title: CpG methylation at promoter site -140 inactivates TGFbeta2 receptor gene in prostate cancer.
Journal: Cancer 20050701
Title: Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma.
Journal: Laboratory investigation; a journal of technical methods and pathology 20050701
Title: Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid.
Journal: Leukemia research 20050701
Title: Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms.
Journal: Cancer biology & therapy 20050701
Title: Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050701
Title: Introduction: emerging role of epigenetic therapy: focus on decitabine.
Journal: Seminars in hematology 20050701
Title: Decitabine dosing schedules.
Journal: Seminars in hematology 20050701
Title: Decitabine in myelodysplastic syndromes.
Journal: Seminars in hematology 20050701
Title: Decitabine in acute myeloid leukemia.
Journal: Seminars in hematology 20050701
Title: Decitabine in chronic leukemias.
Journal: Seminars in hematology 20050701
Title: Pharmacology of 5-Aza-2'-deoxycytidine (decitabine).
Journal: Seminars in hematology 20050701
Title: Induction of HLA-G expression in a melanoma cell line OCM-1A following the treatment with 5-aza-2'-deoxycytidine.
Journal: Cell research 20050701
Title: Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.
Journal: The Journal of biological chemistry 20050617
Title: Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610
Title: TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610
Title: Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610
Title: Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer.
Journal: Genes, chromosomes & cancer 20050601
Title: Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes.
Journal: International immunology 20050601
Title: Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.
Journal: Cancer research 20050601
Title: Methylation silencing of the Apaf-1 gene in acute leukemia.
Journal: Molecular cancer research : MCR 20050601
Title: Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer.
Journal: Molecular cancer research : MCR 20050601
Title: 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.
Journal: International journal of cancer 20050501
Title: Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments.
Journal: European journal of human genetics : EJHG 20050501
Title: Loss of caspase-1 gene expression in human gastric carcinomas and cell lines.
Journal: International journal of oncology 20050501
Title: RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression.
Journal: Cancer research 20050501
Title: The controversial denouement of vertebrate DNA methylation research.
Journal: Biochemistry. Biokhimiia 20050501
Title: Methylation of CpG islands in the rat 7-dehydrocholesterol reductase promoter suppresses transcriptional activation.
Journal: Molecules and cells 20050430
Title: De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine.
Journal: Oncogene 20050428
Title: Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation.
Journal: British journal of cancer 20050425
Title: Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase.
Journal: The Journal of biological chemistry 20050422
Title: Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Journal: Human molecular genetics 20050415
Title: Co-culture of human CD34+ cells with mesenchymal stem cells increases the survival of CD34+ cells against the 5-aza-deoxycytidine- or trichostatin A-induced cell death.
Journal: Biochemical and biophysical research communications 20050415
Title: Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2'-deoxycytidine.
Journal: Biology of reproduction 20050401
Title: Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors.
Journal: The Journal of clinical endocrinology and metabolism 20050401
Title: Epigenetic and genetic alterations of p33ING1b in ovarian cancer.
Journal: Carcinogenesis 20050401
Title: Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.
Journal: International journal of oncology 20050401
Title: Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency.
Journal: International journal of oncology 20050401
Title: Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
Journal: International journal of oncology 20050401
Title: Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells.
Journal: Cancer research 20050401
Title: Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells.
Journal: Cancer research 20050401
Title: [Analysis of the methylation in the promoter of LRP15 gene and its expression].
Journal: Zhongguo shi yan xue ye xue za zhi 20050401
Title: Aberrant CpG island hypermethylation profile is associated with atypical and anaplastic meningiomas.
Journal: Human pathology 20050401
Title: Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells.
Journal: Oncogene 20050331
Title: Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour.
Journal: British journal of cancer 20050328
Title: Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays.
Journal: Cancer research 20050315
Title: Regulation of replication at the R/G chromosomal band boundary and pericentromeric heterochromatin of mammalian cells.
Journal: Experimental cell research 20050310
Title: Cell type-specific regulation of the TGF-beta-responsive alpha2(I) collagen gene by CpG methylation.
Journal: Journal of cellular physiology 20050301
Title: Expression of aquaporin-5 in and fluid secretion from immortalized human salivary gland ductal cells by treatment with 5-aza-2'-deoxycytidine: a possibility for improvement of xerostomia in patients with Sjögren's syndrome.
Journal: Laboratory investigation; a journal of technical methods and pathology 20050301
Title: Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia.
Journal: Anti-cancer drugs 20050301
Title: Aberrant methylation of Reprimo in lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20050301
Title: Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells.
Journal: Cancer research 20050301
Title: Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.
Journal: Molecular cancer therapeutics 20050301
Title: Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas.
Journal: Neoplasia (New York, N.Y.) 20050301
Title: The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.
Journal: Journal of biochemistry 20050301
Title: Structural and functional preservation of specific sequences of DNA and mRNA in apoptotic bodies from ES cells.
Journal: Apoptosis : an international journal on programmed cell death 20050301
Title: [5-Aza-2'-deoxycytidine enhances differentiation and apoptosis induced by phenylbutyrate in Kasumi-1 cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050301
Title: Therapeutic epigenetics: an emerging clinical approach to hematologic malignancies.
Journal: Clinical advances in hematology & oncology : H&O 20050301
Title: Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness.
Journal: International journal of cancer 20050210
Title: Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies.
Journal: International journal of cancer 20050210
Title: In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents.
Journal: The EMBO journal 20050209
Title: Methylation-regulated expression of cancer testis antigens in primary effusion lymphoma: immunotherapeutic implications.
Journal: Journal of cellular physiology 20050201
Title: Oncogene regulation of tumor suppressor genes in tumorigenesis.
Journal: Carcinogenesis 20050201
Title: Silencing of the maternally imprinted tumor suppressor ARHI contributes to follicular thyroid carcinogenesis.
Journal: The Journal of clinical endocrinology and metabolism 20050201
Title: Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050201
Title: Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050201
Title: Silencing of the thrombomodulin gene in human malignant melanoma.
Journal: Melanoma research 20050201
Title: Activation of CMV promoter-controlled glycosyltransferase and beta -galactosidase glycogenes by butyrate, tricostatin A, and 5-aza-2'-deoxycytidine.
Journal: Glycoconjugate journal 20050201
Title: Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma.
Journal: Oncogene 20050127
Title: Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine.
Journal: Life sciences 20050121
Title: Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma.
Journal: International journal of cancer 20050120
Title: Characterization of {gamma}-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer.
Journal: Cancer research 20050115
Title: Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050115
Title: Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.
Journal: Oncogene 20050106
Title: Downregulation of connexin 26 in human lung cancer is related to promoter methylation.
Journal: International journal of cancer 20050101
Title: Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms.
Journal: Leukemia 20050101
Title: Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma.
Journal: Neoplasia (New York, N.Y.) 20050101
Title: Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain.
Journal: Cell transplantation 20050101
Title: X-inactivation status varies in human embryonic stem cell lines.
Journal: Stem cells (Dayton, Ohio) 20050101
Title: Establishment of a detection system for demethylating agents using an endogenous promoter CpG island.
Journal: Mutation research 20041221
Title: Inactivation of the hMSH3 mismatch repair gene in bladder cancer.
Journal: Biochemical and biophysical research communications 20041217
Title: Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine.
Journal: Cancer research 20041215
Title: Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines.
Journal: Cell death and differentiation 20041201
Title: Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells.
Journal: Human molecular genetics 20041201
Title: Nonclonal neutrophil responses after successful treatment of myelodysplasia with low-dose 5-aza-2'-deoxycytidine (decitabine).
Journal: Leukemia research 20041201
Title: DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells.
Journal: Journal of molecular endocrinology 20041201
Title: Decitabine. MGI Pharma Inc/SuperGen Inc.
Journal: IDrugs : the investigational drugs journal 20041201
Title: Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.
Journal: Molecular cancer research : MCR 20041201
Title: Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells.
Journal: Cancer biology & therapy 20041201
Title: Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines.
Journal: Cancer letters 20041125
Title: Silencing the critics: new studies move closer to answering epigenetic questions.
Journal: Journal of the National Cancer Institute 20041117
Title: Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression.
Journal: Blood 20041115
Title: Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality.
Journal: Oncology reports 20041101
Title: Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma.
Journal: The American journal of pathology 20041101
Title: Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20041101
Title: Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer.
Journal: International journal of cancer 20041020
Title: Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression.
Journal: The Journal of clinical investigation 20041015
Title: The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
Title: Microarray analysis of gene regulation in the Hepa1c1c7 cell line following exposure to the DNA methylation inhibitor 5-aza-2'-deoxycytidine and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20041001
Title: Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.
Journal: Cancer cell 20041001
Title: [Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20041001
Title: The role of fetal hemoglobin-enhancing agents in thalassemia.
Journal: Seminars in hematology 20041001
Title: Issues regarding study design for initial clinical trials using decitabine.
Journal: Seminars in hematology 20041001
Title: 5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells.
Journal: Oncogene 20040902
Title: Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040901
Title: Demethylating agent 5-aza-2'-deoxycytidine enhances expression of TNFRI and promotes TNF-mediated apoptosis in vitro and in vivo.
Journal: Oncology reports 20040901
Title: Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine.
Journal: Oncology reports 20040901
Title: Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas.
Journal: International journal of oncology 20040901
Title: DNA hypo-methylating agents and sickle cell disease.
Journal: British journal of haematology 20040901
Title: CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer.
Journal: Cancer research 20040901
Title: Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040901
Title: Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.
Journal: Cancer science 20040901
Title: DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.
Journal: Cancer letters 20040830
Title: Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding.
Journal: The Journal of biological chemistry 20040813
Title: The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma.
Journal: Cancer immunity 20040809
Title: Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells.
Journal: Laboratory investigation; a journal of technical methods and pathology 20040801
Title: Myelodysplasia, megakaryocytes, and methylation.
Journal: Leukemia research 20040801
Title: The effects of 5-aza-2'-deoxycytidine (Decitabine) on the platelet count in patients with intermediate and high-risk myelodysplastic syndromes.
Journal: Leukemia research 20040801
Title: Demethylation of DNA by decitabine in cancer chemotherapy.
Journal: Expert review of anticancer therapy 20040801
Title: Apoptotic speck protein-like, a highly homologous protein to apoptotic speck protein in the pyrin domain, is silenced by DNA methylation and induces apoptosis in human hepatocellular carcinoma.
Journal: Cancer research 20040801
Title: Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer.
Journal: Cancer research 20040801
Title: [Effect of 5-aza-2'-deoxycytidine on cell of high-risk patients with myelodysplastic syndrome in vitro].
Journal: Zhongguo shi yan xue ye xue za zhi 20040801
Title: [Growth and gene expression of leukemia cell after treated with methylation inhibitor 5-aza-2'-deoxycytidine].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040801
Title: Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.
Journal: British journal of cancer 20040719
Title: HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells.
Journal: Cancer research 20040715
Title: Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.
Journal: The Journal of biological chemistry 20040702
Title: Effects of demethylating agent 5-aza-2(')-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines.
Journal: Oral oncology 20040701
Title: MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias.
Journal: Leukemia 20040701
Title: Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers.
Journal: Oncology reports 20040701
Title: Methylation-associated silencing of the heat shock protein 47 gene in human neuroblastoma.
Journal: Cancer research 20040701
Title: Aberrant gene expression in human non small cell lung carcinoma cells exposed to demethylating agent 5-aza-2'-deoxycytidine.
Journal: Neoplasia (New York, N.Y.) 20040701
Title: Epigenetic modifications affect Dnmt3L expression.
Journal: The Biochemical journal 20040615
Title: The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.
Journal: Oncogene 20040610
Title: Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells.
Journal: FEBS letters 20040604
Title: Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A.
Journal: Blood 20040601
Title: MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine.
Journal: Cancer biology & therapy 20040601
Title: Antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and depsipeptide on Raji lymphoma cells.
Journal: Oncology reports 20040601
Title: Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Journal: Cancer research 20040601
Title: The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies.
Journal: The Journal of clinical investigation 20040601
Title: Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116.
Journal: Cell research 20040601
Title: Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene.
Journal: Cancer biology & therapy 20040601
Title: Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling.
Journal: Carcinogenesis 20040501
Title: DNA methylation profiles of lymphoid and hematopoietic malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040501
Title: Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth.
Journal: Chest 20040501
Title: Hypermethylation of the PTEN gene in ovarian cancer cell lines.
Journal: Cancer letters 20040430
Title: Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells.
Journal: The Journal of biological chemistry 20040423
Title: Cancer chemotherapy targeted at reactivating the expression of epigenetically inactivated genes.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415
Title: Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor.
Journal: Cancer research 20040415
Title: Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas.
Journal: International journal of cancer 20040410
Title: 5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.
Journal: The Journal of biological chemistry 20040409
Title: Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma.
Journal: Oncology reports 20040401
Title: Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers.
Journal: Cancer research 20040401
Title: Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040401
Title: The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040401
Title: Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas.
Journal: Journal of the National Cancer Institute 20040317
Title: Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia.
Journal: Cancer research 20040315
Title: Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells.
Journal: Oncogene 20040304
Title: Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies.
Journal: Blood 20040301
Title: Hypermethylation of retrotransposons in the liverwort Marchantia paleacea var. diptera.
Journal: Plant cell reports 20040301
Title: DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells.
Journal: Journal of neurochemistry 20040301
Title: Genomic surgery for lung cancer.
Journal: The Journal of surgical research 20040301
Title: Transplacental exposure to the DNA demethylating agent, 5-AZA-CdR, affects the sexual behavior of CD-1 male mice.
Journal: Neurotoxicology 20040301
Title: Aberrant expression of the maspin gene associated with epigenetic modification in melanoma cells.
Journal: The Journal of investigative dermatology 20040301
Title: Methylation of a CpG island within the uroplakin Ib promoter: a possible mechanism for loss of uroplakin Ib expression in bladder carcinoma.
Journal: Neoplasia (New York, N.Y.) 20040301
Title: 5-Aza-2'-deoxycytidine stimulates inducible nitric oxide synthase induction in C6 astrocytoma cells.
Journal: Brain research 20040213
Title: 5-Aza-2'-deoxycytidine and paclitaxel inhibit inducible nitric oxide synthase activation in fibrosarcoma cells.
Journal: European journal of pharmacology 20040206
Title: Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers.
Journal: Oncogene 20040205
Title: [Effect of inhibitors for demethylation and histone deacetylase on proliferation of cell line K562 and expression of tumor related genes].
Journal: Zhongguo shi yan xue ye xue za zhi 20040201
Title: Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines.
Journal: Anti-cancer drugs 20040201
Title: The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine.
Journal: Oncogene 20040122
Title: Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
Journal: Cancer letters 20040120
Title: In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.
Journal: Blood 20040101
Title: Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.
Journal: Molecular carcinogenesis 20040101
Title: CHFR-associated early G2/M checkpoint defects in breast cancer cells.
Journal: Molecular carcinogenesis 20040101
Title: Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine.
Journal: Molecular pharmacology 20040101
Title: 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines.
Journal: Chinese medical journal 20040101
Title: Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.
Journal: Molecular cancer research : MCR 20040101
Title: Activation of expression of p15, p73 and E-cadherin in leukemic cells by different concentrations of 5-aza-2'-deoxycytidine (Decitabine).
Journal: Anticancer research 20040101
Title: Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by phenylbutyrate on L1210 leukemic cells.
Journal: Leukemia & lymphoma 20040101
Title: 5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.
Journal: Clinical & experimental metastasis 20040101
Title: Formation of mitoxantrone adducts in human tumor cells: potentiation by AN-9 and DNA methylation.
Journal: Oncology research 20040101
Title: Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma.
Journal: BMC cancer 20040101
Title: New nucleoside analogs in the treatment of solid tumors.
Journal: Acta poloniae pharmaceutica 20040101
Title: The role of methyltransferase inhibitors in the management of the myelodysplastic syndromes.
Journal: Cancer control : journal of the Moffitt Cancer Center 20040101
Title: Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.
Journal: Clinical & experimental metastasis 20040101
Title: Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease.
Journal: Clinical advances in hematology & oncology : H&O 20040101
Title: Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice.
Journal: Oncogene 20031218
Title: Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031215
Title: Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma.
Journal: Cancer research 20031215
Title: [The study of 5-Aza-2'-deoxycytidine on transcription regulation of p16/CDKN2 gene demethylation in RKO human colorectal cell line].
Journal: Zhonghua yi xue za zhi 20031210
Title: Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation.
Journal: Oncogene 20031204
Title: The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.
Journal: American journal of respiratory cell and molecular biology 20031201
Title: Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease.
Journal: Blood 20031201
Title: The histone code regulating expression of the imprinted mouse Igf2r gene.
Journal: Endocrinology 20031201
Title: Promoter methylation of cyclin D2 gene in gastric carcinoma.
Journal: International journal of oncology 20031201
Title: Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma.
Journal: Molecular carcinogenesis 20031201
Title: DNA methylation in haematological malignancies: the role of decitabine.
Journal: Expert opinion on investigational drugs 20031201
Title: DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.
Journal: Hepatology (Baltimore, Md.) 20031201
Title: Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine.
Journal: Electrophoresis 20031201
Title: [DNA methylation and cancer--DNA methylation as a target of cancer chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20031201
Title: Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies.
Journal: Current opinion in investigational drugs (London, England : 2000) 20031201
Title: Demethylation of host-cell DNA at the site of avian retrovirus integration.
Journal: Biochemical and biophysical research communications 20031121
Title: Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).
Journal: International journal of cancer 20031120
Title: Genetic and epigenetic alterations of DLC-1 gene in hepatocellular carcinoma.
Journal: Cancer research 20031115
Title: Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer.
Journal: Cancer research 20031115
Title: Comment on 'Chromosomal instability and tumors promoted by DNA hypomethylation' and 'Induction of tumors in nice by genomic hypomethylation'.
Journal: Science (New York, N.Y.) 20031114
Title: Silencing of CDX2 expression in colon cancer via a dominant repression pathway.
Journal: The Journal of biological chemistry 20031107
Title: Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway.
Journal: Leukemia research 20031101
Title: Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
Journal: Cancer research 20031101
Title: Decitabine.
Journal: Current opinion in oncology 20031101
Title: Epigenetic silencing of the HIC-1 gene in human medulloblastomas.
Journal: Journal of neuropathology and experimental neurology 20031101
Title: Role of promoter methylation in regulation of the mammalian heparanase gene.
Journal: Oncogene 20031030
Title: Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors.
Journal: Oncogene 20031030
Title: Transcriptional regulation of mouse delta-opioid receptor gene by CpG methylation: involvement of Sp3 and a methyl-CpG-binding protein, MBD2, in transcriptional repression of mouse delta-opioid receptor gene in Neuro2A cells.
Journal: The Journal of biological chemistry 20031017
Title: Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.
Journal: Oncogene 20031016
Title: Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
Journal: Oncogene 20031009
Title: Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres.
Journal: Experimental cell research 20031001
Title: Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.
Journal: The American journal of pathology 20031001
Title: Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model.
Journal: The Journal of pathology 20031001
Title: Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma.
Journal: Cancer research 20031001
Title: Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS.
Journal: Clinical immunology (Orlando, Fla.) 20031001
Title: A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.
Journal: Breast cancer research and treatment 20031001
Title: Novel biospecific agents for the treatment of myelodysplastic syndromes.
Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20031001
Title: Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells.
Journal: The Journal of biological chemistry 20030926
Title: Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas.
Journal: Cancer letters 20030925
Title: Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation.
Journal: The Journal of biological chemistry 20030919
Title: Expression profiling reveals that methylation of TIMP3 is involved in uveal melanoma development.
Journal: International journal of cancer 20030910
Title: Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine.
Journal: Biology of reproduction 20030901
Title: Epigenetic inactivation of RASSF1A in head and neck cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030901
Title: Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control.
Journal: Neoplasia (New York, N.Y.) 20030901
Title: Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter.
Journal: Gene 20030814
Title: Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma.
Journal: International journal of cancer 20030810
Title: Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.
Journal: International journal of cancer 20030810
Title: Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity in oral squamous cell carcinomas.
Journal: International journal of oncology 20030801
Title: Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia.
Journal: Cancer 20030801
Title: Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.
Journal: Cancer research 20030801
Title: Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis.
Journal: Cancer research 20030801
Title: Epigenetic down-regulation of death-associated protein kinase in lung cancers.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
Title: Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
Title: Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma.
Journal: Biochemical and biophysical research communications 20030718
Title: Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
Journal: Cancer research 20030715
Title: Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos.
Journal: Biology of reproduction 20030701
Title: Epigenetic inactivation of laminin-5-encoding genes in lung cancers.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701
Title: Restoration of silenced Peutz-Jeghers syndrome gene, LKB1, induces apoptosis in pancreatic carcinoma cells.
Journal: Neoplasia (New York, N.Y.) 20030701
Title: Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.
Journal: Oncogene 20030626
Title: Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia.
Journal: International journal of cancer 20030620
Title: Methylation-regulated expression of HLA class I antigens in melanoma.
Journal: International journal of cancer 20030620
Title: Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells.
Journal: Oncogene 20030619
Title: 5-Aza-2'-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach?
Journal: Blood 20030601
Title: DNA mismatch repair genes in renal cell carcinoma.
Journal: The Journal of urology 20030601
Title: Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer.
Journal: Cancer science 20030601
Title: Susceptibility to postnatal growth retardation induced by 5-AZA-2'-deoxycytidine in utero: gender specificity and correlation with reduced insulin-like growth factor 1.
Journal: Life sciences 20030509
Title: Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells.
Journal: Leukemia research 20030501
Title: Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.
Journal: Leukemia research 20030501
Title: Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants.
Journal: Journal of experimental botany 20030501
Title: Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030501
Title: JunB gene expression is inactivated by methylation in chronic myeloid leukemia.
Journal: Blood 20030415
Title: DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers.
Journal: Cancer research 20030415
Title: Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4A/pRb.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401
Title: Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype.
Journal: Leukemia 20030401
Title: Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030401
Title: Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples.
Journal: The Journal of clinical investigation 20030315
Title: Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias.
Journal: Cancer 20030301
Title: A systematic profile of DNA methylation in human cancer cell lines.
Journal: Cancer research 20030301
Title: Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030301
Title: Interaction of 5-aza-2'-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells.
Journal: Anti-cancer drugs 20030301
Title: Phase I trial of continuous infusion 5-aza-2'-deoxycytidine.
Journal: Cancer chemotherapy and pharmacology 20030301
Title: E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours.
Journal: European journal of cancer (Oxford, England : 1990) 20030301
Title: Therapies to increase fetal hemoglobin in sickle cell disease.
Journal: Current hematology reports 20030301
Title: Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness.
Journal: Journal of the National Cancer Institute 20030219
Title: On the use of DNA methylation inhibitors and the reversal of transcriptional silencing.
Journal: Blood 20030215
Title: Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma.
Journal: Genes, chromosomes & cancer 20030201
Title: Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.
Journal: International journal of oncology 20030201
Title: Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma.
Journal: Cancer research 20030201
Title: Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma.
Journal: Cell death and differentiation 20030201
Title: Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia.
Journal: Oncogene 20030123
Title: Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers.
Journal: Cancer genetics and cytogenetics 20030115
Title: Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2'-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells.
Journal: International journal of cancer 20030110
Title: 5-AZA-2'-deoxycytidine (5-AZA-CdR): a demethylating agent affecting development and reproductive capacity.
Journal: Journal of applied toxicology : JAT 20030101
Title: An epigenetic approach for finding tumor suppressors.
Journal: Cell cycle (Georgetown, Tex.) 20030101
Title: Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T- and natural killer (NK)/T-cell malignancies.
Journal: Cancer science 20030101
Title: Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716.
Journal: Drugs in R&D 20030101
Title: Inactivation of the RASSF1A in osteosarcoma.
Journal: Oncology reports 20030101
Title: 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome.
Journal: Journal of andrology 20030101
Title: Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716.
Journal: Drugs in R&D 20030101
Title: Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.
Journal: Cancer biology & therapy 20030101
Title: Induction of the estrogen receptor by ablation of DNMT1 in ER-negative breast cancer cells.
Journal: Cancer biology & therapy 20030101
Title: Hemoglobinopathies.
Journal: Hematology. American Society of Hematology. Education Program 20030101
Title: Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.
Journal: Cancer research 20021215
Title: An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin.
Journal: Nature genetics 20021201
Title: Induction of TRAG-3 expression in A549 lung adenocarcinoma cell line by 5-aza-2' deoxyazacytidine.
Journal: Lung cancer (Amsterdam, Netherlands) 20021201
Title: Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Journal: Cancer cell 20021201
Title: Decitabine has promising clinical activity in chronic myeloid leukemia.
Journal: Expert review of anticancer therapy 20021201
Title: The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation.
Journal: Carcinogenesis 20021201
Title: Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
Journal: Cancer research 20021115
Title: Re-expression of p16 gene in the myeloma cell line U266 induced by synergy of sodium butyrate and 5-Aza-2'-deoxycytidine.
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021101
Title: [The re-expression of p15(INK4B) gene in leukemia cells induced by in vitro DNA methyltransferase and histone deacetylase inhibition].
Journal: Zhonghua nei ke za zhi 20021101
Title: Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment.
Journal: Blood 20021015
Title: Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021015
Title: Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.
Journal: Cancer research 20021015
Title: Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells.
Journal: The Journal of biological chemistry 20021011
Title: Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation.
Journal: Journal of molecular biology 20021011
Title: Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome.
Journal: American journal of human genetics 20021001
Title: Seeking a way to alleviate sickle cell disease.
Journal: JAMA 20021001
Title: Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix.
Journal: American journal of clinical oncology 20021001
Title: [Apoptosis and re-expression of p16 gene in the myeloma cell line U266 induced by synergy of histone deacetylase inhibitor and demethylating agent].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20021001
Title: DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.
Journal: The Journal of biological chemistry 20020927
Title: Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells.
Journal: Cancer letters 20020926
Title: Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells.
Journal: Circulation research 20020920
Title: New drugs in acute myeloid leukemia.
Journal: Current oncology reports 20020901
Title: Antineoplastic action of 5-aza-2'-deoxycytidine and phenylbutyrate on human lung carcinoma cells.
Journal: Anti-cancer drugs 20020901
Title: 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.
Journal: Oncogene 20020812
Title: Reactivating the expression of methylation silenced genes in human cancer.
Journal: Oncogene 20020812
Title: 5-aza-2'-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020801
Title: Role of DNA methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus.
Journal: The Journal of rheumatology 20020801
Title: [Inhibitory effect on proliferation of KG1a cell line by methyltransferase inhibitors].
Journal: Zhongguo shi yan xue ye xue za zhi 20020801
Title: Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020701
Title: Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers.
Journal: International journal of cancer 20020701
Title: SNPs in the CpG island of NAP1L2: a possible link between DNA methylation and neural tube defects?
Journal: American journal of medical genetics 20020701
Title: Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells.
Journal: Oncogene 20020620
Title: Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.
Journal: British journal of cancer 20020617
Title: DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA.
Journal: European journal of pharmacology 20020607
Title: Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia.
Journal: Blood 20020601
Title: DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines.
Journal: Molecular immunology 20020601
Title: Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids.
Journal: Plant physiology 20020601
Title: Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene.
Journal: Biochemical and biophysical research communications 20020524
Title: In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer.
Journal: British journal of cancer 20020520
Title: Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
Journal: Oncogene 20020502
Title: Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020501
Title: Hypertonicity induction of melanoma antigen, a tumor-associated antigen.
Journal: Molecules and cells 20020430
Title: Cell division is required for de novo methylation of CpG islands in bladder cancer cells.
Journal: Cancer research 20020415
Title: Differentiation therapy for myelodysplastic syndrome.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020401
Title: Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020401
Title: 5-Aza-2'-deoxycytidine-induced cytotoxicity and limb reduction defects in the mouse.
Journal: Teratology 20020401
Title: Review of the clinical experience with 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumors.
Journal: Current opinion in investigational drugs (London, England : 2000) 20020401
Title: p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma.
Journal: Oncogene 20020314
Title: High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020301
Title: Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis.
Journal: Chromosoma 20020301
Title: Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma.
Journal: Cancer letters 20020225
Title: Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture.
Journal: The Journal of biological chemistry 20020215
Title: Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolitic chemotherapeutic drugs in Drosophila melanogaster.
Journal: Mutation research 20020215
Title: Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine.
Journal: Cancer research 20020215
Title: The 5-lipoxygenase promoter is regulated by DNA methylation.
Journal: The Journal of biological chemistry 20020208
Title: Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
Journal: Science (New York, N.Y.) 20020208
Title: Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity.
Journal: International journal of oncology 20020201
Title: Lack of a consistent relationship between demethylation of the CD44 promoter and CD44 expression.
Journal: Immunogenetics 20020201
Title: Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer.
Journal: Carcinogenesis 20020201
Title: Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer.
Journal: International journal of cancer 20020120
Title: Characterization of XAGE-1b, a short major transcript of cancer/testis-associated gene XAGE-1, induced in melanoma metastasis.
Journal: International journal of cancer 20020110
Title: Novel agents for the therapy of acute leukemia.
Journal: Current opinion in oncology 20020101
Title: De novo expression of the Muc2 gene in pancreas carcinoma cells is triggered by promoter demethylation.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20020101
Title: Expression spectrum and methylation-dependent regulation of melanoma antigen-encoding gene family members in pancreatic cancer cells.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101
Title: Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines.
Journal: Anticancer research 20020101
Title: MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas.
Journal: Journal of human genetics 20020101
Title: [Telomerase: an enzyme with multiple applications in cancer research].
Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20020101
Title: Characteristic promoter hypermethylation signatures in male germ cell tumors.
Journal: Molecular cancer 20020101
Title: 5-aza-2'-deoxycytidine induces retinoic acid receptor beta 2 demethylation, cell cycle arrest and growth inhibition in breast carcinoma cells.
Journal: Anticancer research 20020101
Title: A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers.
Journal: Anticancer research 20020101
Title: Potential of 5-aza-2'-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20011201
Title: Reexpression of a cluster of silenced transgenes is associated with their rearrangement.
Journal: Genes, chromosomes & cancer 20011201
Title: Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer.
Journal: British journal of cancer 20011201
Title: [Chemotherapy and radiation therapy].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20011201
Title: Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells.
Journal: Oncogene 20011122
Title: Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily.
Journal: Cancer research 20011115
Title: 5-Aza-2'-deoxycytidine induces histone hyperacetylation of mouse centromeric heterochromatin by a mechanism independent of DNA demethylation.
Journal: Biochemical and biophysical research communications 20011109
Title: E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells.
Journal: Cancer letters 20011108
Title: Diminished expression of S100A2, a putative tumor suppressor, at early stage of human lung carcinogenesis.
Journal: Cancer research 20011101
Title: CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression.
Journal: Cancer research 20011101
Title: Glypican-3 expression is silenced in human breast cancer.
Journal: Oncogene 20011101
Title: Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.
Journal: The Journal of biological chemistry 20011026
Title: Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression.
Journal: Oncogene 20011025
Title: CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma.
Journal: Cancer 20011015
Title: Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatment.
Journal: International journal of cancer 20011015
Title: DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas.
Journal: Carcinogenesis 20011001
Title: Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.
Journal: Cancer research 20011001
Title: Reduced expression of syndecan-1 affects metastatic potential and clinical outcome in patients with colorectal cancer.
Journal: Japanese journal of cancer research : Gann 20011001
Title: Pharmacological reactivation of inactive genes: the fragile X experience.
Journal: Brain research bulletin 20011001
Title: Histone deacetylase and DNA methyltransferase in human prostate cancer.
Journal: Biochemical and biophysical research communications 20010928
Title: Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer.
Journal: Oncogene 20010913
Title: Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma.
Journal: International journal of cancer 20010901
Title: Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells.
Journal: British journal of cancer 20010901
Title: CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma.
Journal: Molecular carcinogenesis 20010901
Title: Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma.
Journal: Molecular carcinogenesis 20010901
Title: Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines.
Journal: Japanese journal of cancer research : Gann 20010901
Title: Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene.
Journal: Cancer gene therapy 20010901
Title: Evolving treatment options of myelodysplastic syndromes.
Journal: Annals of hematology 20010901
Title: Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences.
Journal: Oncogene 20010823
Title: Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2.
Journal: Cancer research 20010815
Title: DNA methylation regulates placental lactogen I gene expression.
Journal: Endocrinology 20010801
Title: Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos.
Journal: Development, growth & differentiation 20010801
Title: Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine.
Journal: British journal of haematology 20010801
Title: Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation.
Journal: Cancer letters 20010710
Title: Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma.
Journal: Cancer research 20010701
Title: Loss of mismatch repair activity in simian virus 40 large T antigen-immortalized BPH-1 human prostatic epithelial cell line.
Journal: Molecular carcinogenesis 20010701
Title: Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells.
Journal: Cancer chemotherapy and pharmacology 20010701
Title: Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.
Journal: Cancer research 20010615
Title: Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells.
Journal: Cancer research 20010601
Title: Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: results of a phase I study.
Journal: Bone marrow transplantation 20010601
Title: Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer.
Journal: Cancer research 20010515
Title: 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
Journal: Cancer research 20010501
Title: Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.
Journal: Molecular pharmacology 20010401
Title: Association of acetylated histones with paternally expressed genes in the Prader--Willi deletion region.
Journal: Human molecular genetics 20010315
Title: Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
Journal: Biochemical pharmacology 20010315
Title: Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease.
Journal: Current opinion in hematology 20010301
Title: Analysis of the ANA gene as a candidate for the chromosome 21q oral cancer susceptibility locus.
Journal: British journal of cancer 20010301
Title: Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo.
Journal: International journal of cancer 20010301
Title: Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.
Journal: Cancer research 20010301
Title: Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.
Journal: Cancer research 20010215
Title: DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.
Journal: Cancer research 20010215
Title: Unbalanced expression of HLA-A and -B antigens: a specific feature of cutaneous melanoma and other non-hemopoietic malignancies reverted by IFN-gamma.
Journal: International journal of cancer 20010215
Title: Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2.
Journal: World journal of gastroenterology 20010215
Title: Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.
Journal: British journal of haematology 20010201
Title: Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.
Journal: Cancer research 20010201
Title: Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites.
Journal: The Journal of biological chemistry 20010105
Title: Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer.
Journal: The American journal of pathology 20010101
Title: Induction of MAGE-3 expression in lung and esophageal cancer cells.
Journal: The Annals of thoracic surgery 20010101
Title: Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies.
Journal: Lupus 20010101
Title: Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties.
Journal: Nucleosides, nucleotides & nucleic acids 20010101
Title: Demethylation by 5-aza-2'-deoxycytidine (5-azadC) of p16INK4A gene results in downregulation of vascular endothelial growth factor expression in human lung cancer cell lines.
Journal: Oncology research 20010101
Title: Altered hox gene expression and cellular pathogenesis of 5-aza-2'-deoxycytidine-induced murine hindlimb dysmorphogenesis.
Journal: Toxicologic pathology 20010101
Title: Targeting hypomethylation of DNA to achieve cellular differentiation in myelodysplastic syndromes (MDS).
Journal: The oncologist 20010101
Title: Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer.
Journal: Anti-cancer drugs 19970401
Title: Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines.
Journal: Anti-cancer drugs 19931201
Title: Increased sensitivity of nontumorigenic fibroblasts expressing ras or myc oncogenes to malignant transformation induced by 5-aza-2'-deoxycytidine.
Journal: Cancer research 19910101
Title: 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro.
Journal: Antimicrobial agents and chemotherapy 19900201
Title: Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity.
Journal: Chemico-biological interactions 19880101
Title: Cellular differentiation, cytidine analogs and DNA methylation.
Journal: Cell 19800501
