Title: Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs.
Journal: American journal of physiology. Lung cellular and molecular physiology 20130415
Title: Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.
Journal: Clinical science (London, England : 1979) 20121201
Title: CD11c(+)/CD11b(+) cells are critical for organic dust-elicited murine lung inflammation.
Journal: American journal of respiratory cell and molecular biology 20121101
Title: Macrophage/monocyte depletion by clodronate, but not diphtheria toxin, improves renal ischemia/reperfusion injury in mice.
Journal: Kidney international 20121001
Title: Monocytes control second-phase neutrophil emigration in established lipopolysaccharide-induced murine lung injury.
Journal: American journal of respiratory and critical care medicine 20120915
Title: Effects of low-dose doxycycline and bisphosphonate clodronate on alveolar bone loss and gingival levels of matrix metalloproteinase-9 and interleukin-1β in rats with diabetes: a histomorphometric and immunohistochemical study.
Journal: Journal of periodontology 20120901
Title: Critical involvement of macrophage infiltration in the development of Sjögren's syndrome-associated dry eye.
Journal: The American journal of pathology 20120901
Title: Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120801
Title: Bisphosphonates in early breast cancer.
Journal: The Lancet. Oncology 20120701
Title: Oral clodronate for adjuvant treatment of operable breast cancer (National Surgical Adjuvant Breast and Bowel Project protocol B-34): a multicentre, placebo-controlled, randomised trial.
Journal: The Lancet. Oncology 20120701
Title: Nanoparticle-based clodronate delivery mitigates murine experimental colitis.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120628
Title: Effects of induction and maintenance plus long-term bisphosphonates on bone disease in patients with multiple myeloma: the Medical Research Council Myeloma IX Trial.
Journal: Blood 20120607
Title: Bisphosphonates in multiple myeloma: a network meta-analysis.
Journal: The Cochrane database of systematic reviews 20120516
Title: Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis.
Journal: Laboratory investigation; a journal of technical methods and pathology 20120501
Title: RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration.
Journal: The Journal of clinical investigation 20120402
Title: Clodronate and hydroxychloroquine in erosive osteoarthritis: a 24-month open randomized pilot study.
Journal: Modern rheumatology 20120401
Title: Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.
Journal: Resuscitation 20120401
Title: Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120401
Title: Osteoclasts derived from patients with neurofibromatosis 1 (NF1) display insensitivity to bisphosphonates in vitro.
Journal: Bone 20120301
Title: Differential detection and distribution of microglial and hematogenous macrophage populations in the injured spinal cord of lys-EGFP-ki transgenic mice.
Journal: Journal of neuropathology and experimental neurology 20120301
Title: Replacement of microglial cells using Clodronate liposome and bone marrow transplantation in the central nervous system of SOD1(G93A) transgenic mice as an in vivo model of amyotrophic lateral sclerosis.
Journal: Biochemical and biophysical research communications 20120210
Title: Influence of bisphosphonates on the osteoblast RANKL and OPG gene expression in vitro.
Journal: Clinical oral investigations 20120201
Title: The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study.
Journal: Clinical oral investigations 20120201
Title: The Medical Research Council Myeloma IX Trial: new clinical insights on the anticancer effects of zoledronic acid in patients with multiple myeloma.
Journal: Clinical lymphoma, myeloma & leukemia 20120201
Title: Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment.
Journal: Clinical and experimental immunology 20120201
Title: Depletion of macrophages and dendritic cells in ischemic acute kidney injury.
Journal: American journal of nephrology 20120201
Title: Depletion of alveolar macrophages prolongs survival in response to acute pneumovirus infection.
Journal: Virology 20120120
Title: The Medical Research Council Myeloma IX trial: the impact on treatment paradigms.
Journal: European journal of haematology 20120101
Title: P-selectin glycoprotein ligand-1 deficiency leads to cytokine resistance and protection against atherosclerosis in apolipoprotein E deficient mice.
Journal: Atherosclerosis 20120101
Title: Development of an injectable two-phase drug delivery system for sequential release of antiresorptive and osteogenic drugs.
Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20120101
Title: Effect of oral clodronate on structural damage and bone turnover in rheumatoid arthritis.
Journal: Clinical and experimental rheumatology 20120101
Title: Neuroprotective function for ramified microglia in hippocampal excitotoxicity.
Journal: Journal of neuroinflammation 20120101
Title: Cost-effectiveness of zoledronic acid vs clodronic acid for newly-diagnosed multiple myeloma from the United Kingdom healthcare system perspective.
Journal: Journal of medical economics 20120101
Title: Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures.
Journal: Journal of neuroinflammation 20120101
Title: Depletion and reconstitution of macrophages in mice.
Journal: Journal of visualized experiments : JoVE 20120101
Title: The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1.
Journal: PloS one 20120101
Title: In vivo imaging implicates CCR2(+) monocytes as regulators of neutrophil recruitment during arthritis.
Journal: Cellular immunology 20120101
Title: Zoledronate, ibandronate and clodronate enhance osteoblast differentiation in a dose dependent manner--a quantitative in vitro gene expression analysis of Dlx5, Runx2, OCN, MSX1 and MSX2.
Journal: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20111201
Title: Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111201
Title: Tissue tropism and target cells of NSs-deleted rift valley fever virus in live immunodeficient mice.
Journal: PLoS neglected tropical diseases 20111201
Title: Microglia-mediated IGF-I neuroprotection in the rd10 mouse model of retinitis pigmentosa.
Journal: Investigative ophthalmology & visual science 20111125
Title: Monocyte/macrophages promote vasculogenesis in choroidal neovascularization in mice by stimulating SDF-1 expression in RPE cells.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20111101
Title: Economic evaluation of clodronate and zoledronate in patients diagnosed with metastatic bone disease from the perspective of public and third party payors in Brazil.
Journal: Clinical therapeutics 20111101
Title: Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells.
Journal: Journal of medicinal chemistry 20111013
Title: Effects of liposome-encapsulated clodronate on chlorhexidine gluconate-induced peritoneal fibrosis in rats.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001
Title: Glycyrrhizin prevents liver injury by inhibition of high-mobility group box 1 production by Kupffer cells after ischemia-reperfusion in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20111001
Title: Bisphosphonate-related osteonecrosis of the jaws associated with photodynamic therapy.
Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20111001
Title: Protective effect of clodronate-containing liposomes on intestinal mucosal injury in rats with severe acute pancreatitis.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20111001
Title: Cytotoxic effect of clodronate and zoledronate on the chondrosarcoma cell lines HTB-94 and CAL-78.
Journal: International orthopaedics 20110901
Title: Further analyses of the Myeloma IX Study.
Journal: Lancet (London, England) 20110827
Title: Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised controlled trial.
Journal: The Lancet. Oncology 20110801
Title: Zoledronic acid for all patients with newly diagnosed multiple myeloma?
Journal: The Lancet. Oncology 20110801
Title: A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI.
Journal: Experimental neurology 20110701
Title: Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial.
Journal: International journal of radiation oncology, biology, physics 20110701
Title: Non-surgical management of stage 3 biphosphonate-related oroantral fistula.
Journal: The British journal of oral & maxillofacial surgery 20110701
Title: Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse.
Journal: International immunopharmacology 20110701
Title: Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110701
Title: Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury.
Journal: The American journal of pathology 20110701
Title: Safety and efficacy of zoledronic acid in multiple myeloma.
Journal: Lancet (London, England) 20110625
Title: Safety and efficacy of zoledronic acid in multiple myeloma.
Journal: Lancet (London, England) 20110625
Title: Zoledronic acid and clodronate in the treatment of malignant bone metastases with hypercalcaemia; efficacy and safety comparative study.
Journal: Medical oncology (Northwood, London, England) 20110601
Title: The influence of macrophage depletion on ligament healing.
Journal: Connective tissue research 20110601
Title: Co-loading of bisphosphonates and antibiotics to a biomimetic hydroxyapatite coating.
Journal: Biotechnology letters 20110601
Title: Susceptibility to infection and inflammatory response following influenza virus (H1N1, A/PR/8/34) challenge: role of macrophages.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110601
Title: Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis.
Journal: PLoS pathogens 20110601
Title: Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen.
Journal: Blood 20110519
Title: Plasmacytoid dendritic cells play a major role in apoptotic leukocyte-induced immune modulation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110515
Title: Macrophage-derived tumor necrosis factor-alpha is an early component of the molecular cascade leading to angiogenesis in response to aortic injury.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20110501
Title: Fluorimetric quantification of clodronate and alendronate in aqueous samples and in serum.
Journal: Talanta 20110415
Title: Optimized electro- and wet-spinning techniques for the production of polymeric fibrous scaffolds loaded with bisphosphonate and hydroxyapatite.
Journal: Journal of tissue engineering and regenerative medicine 20110401
Title: Depletion of antigen-presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie2 mice.
Journal: The British journal of dermatology 20110401
Title: Positive correlation between the generation of reactive oxygen species and activation/reactivation of transgene expression after hydrodynamic injections into mice.
Journal: Pharmaceutical research 20110401
Title: The roles of vitreal macrophages and circulating leukocytes in retinal neovascularization.
Journal: Investigative ophthalmology & visual science 20110314
Title: Osteonecrosis of the posterior mandible after implant insertion: a clinical and histological case report.
Journal: Clinical implant dentistry and related research 20110301
Title: Can clodronate be effective in the treatment of disabling hydroxyapatite crystal-deposition disease? A report of two cases.
Journal: Rheumatology international 20110301
Title: Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro.
Journal: Oral diseases 20110301
Title: Depletion of alveolar macrophages abrogates prolongation of cardiac allograft survival induced by intratracheal delivery of alloantigen.
Journal: Transplantation 20110227
Title: Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).
Journal: Innate immunity 20110201
Title: Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro.
Journal: Clinical oral investigations 20110201
Title: Macrophage-produced IL-12p70 mediates hemorrhage-induced damage in a complement-dependent manner.
Journal: Shock (Augusta, Ga.) 20110201
Title: Interaction of clodronate with fibroblast growth factor 2 reduces FGF2-activity in endothelial cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110201
Title: Bisphosphonates inhibit phosphorylation of signal transducer and activator of transcription 3 and expression of suppressor of cytokine signaling 3: implications for their effects on innate immune function and osteoclastogenesis.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110201
Title: Steady state pharmacokinetics and dose equivalents of oral clodronate in renal failure.
Journal: International journal of clinical pharmacology and therapeutics 20110201
Title: The role of the radiologist when encountering osteoporosis in women.
Journal: AJR. American journal of roentgenology 20110201
Title: Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice.
Journal: Arthritis and rheumatism 20110201
Title: Established role of bisphosphonate therapy for prevention of skeletal complications from myeloma bone disease.
Journal: Critical reviews in oncology/hematology 20110201
Title: Can bisphosphonates improve outcomes in patients with newly diagnosed multiple myeloma?
Journal: Critical reviews in oncology/hematology 20110201
Title: HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.
Journal: Cancer cell 20110118
Title: Effects of two administration schemes of intramuscular clodronic acid on bone mineral density: a randomized, open-label, parallel-group study.
Journal: Clinical drug investigation 20110101
Title: TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.
Journal: The international journal of biochemistry & cell biology 20110101
Title: Supportive therapy in multiple myeloma.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20110101
Title: [Regression of an osteolytic lesion in a patient with multiple myeloma treated with clodronate after a successful therapy with bortezomib-based regimen].
Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101
Title: Transition of tumor-associated macrophages from MHC class II(hi) to MHC class II(low) mediates tumor progression in mice.
Journal: BMC immunology 20110101
Title: Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice.
Journal: PloS one 20110101
Title: Clinical utility of clodronate in the prevention and management of osteoporosis in patients intolerant of oral bisphosphonates.
Journal: Drug design, development and therapy 20110101
Title: Bisphosphonates and breast cancer incidence and recurrence.
Journal: Breast disease 20110101
Title: Inflammatory cytokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
Journal: Journal of neuroimmunology 20101215
Title: Zoledronic acid in myeloma: MRC Myeloma IX.
Journal: Lancet (London, England) 20101211
Title: First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial.
Journal: Lancet (London, England) 20101202
Title: Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.
Journal: Toxicology letters 20101130
Title: The role of Tregs and CD11c(+) macrophages/dendritic cells in ischemic preconditioning of the kidney.
Journal: Kidney international 20101101
Title: Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice.
Journal: Journal of hepatology 20101101
Title: Osteonecrosis of the jaw: effect of bisphosphonate type, local concentration, and acidic milieu on the pathomechanism.
Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20101101
Title: Clodronate-containing liposomes attenuate lung injury in rats with severe acute pancreatitis.
Journal: Journal of Zhejiang University. Science. B 20101101
Title: Effects of clodronate on early alveolar bone remodeling and root resorption related to orthodontic forces: a histomorphometric analysis.
Journal: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20101101
Title: Bisphosphonates as anticancer therapy for early breast cancer.
Journal: Clinical breast cancer 20101001
Title: Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.
Journal: Organic & biomolecular chemistry 20100921
Title: In aged mice, outgrowth of intraocular melanoma depends on proangiogenic M2-type macrophages.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100915
Title: Distinct macrophage subpopulations regulate viral encephalitis but not viral clearance in the CNS.
Journal: Journal of neuroimmunology 20100914
Title: Kupffer cell depletion reduces hepatic inflammation and apoptosis but decreases survival in abdominal sepsis.
Journal: European journal of gastroenterology & hepatology 20100901
Title: Depletion of kidney CD11c+ F4/80+ cells impairs the recovery process in ischaemia/reperfusion-induced acute kidney injury.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100901
Title: Bone-marker levels in patients with prostate cancer: potential correlations with outcomes.
Journal: Current opinion in supportive and palliative care 20100901
Title: Technical advance: autofluorescence as a tool for myeloid cell analysis.
Journal: Journal of leukocyte biology 20100901
Title: Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way.
Journal: Glia 20100901
Title: [Bisphosphonates in adjuvant therapy of breast cancer].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20100901
Title: Transient neutropenia increases macrophage accumulation and cell proliferation but does not improve repair following intratendinous rupture of Achilles tendon.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20100801
Title: Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women: a 5-year follow-up.
Journal: Maturitas 20100801
Title: Involvement of natural killer T cells in halothane-induced liver injury in mice.
Journal: Biochemical pharmacology 20100715
Title: Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100701
Title: Macrophage depletion attenuates chronic cyclosporine A nephrotoxicity.
Journal: Transplantation 20100615
Title: Alkaline and alkaline earth metal complexes of dianhydride derivatives of clodronate and their hydrolysis products.
Journal: Dalton transactions (Cambridge, England : 2003) 20100614
Title: Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601
Title: Decreased periprosthetic bone loss in patients treated with clodronate: a 1-year randomized controlled study.
Journal: Calcified tissue international 20100601
Title: Osteonecrosis of the jaw induced by clodronate, an alkylbiphosphonate: case report and literature review.
Journal: European journal of clinical pharmacology 20100601
Title: The evolving role of bone-conserving therapy in patients with breast cancer.
Journal: Seminars in oncology 20100601
Title: Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100515
Title: Role of brain macrophages on IL-1beta and fatigue following eccentric exercise-induced muscle damage.
Journal: Brain, behavior, and immunity 20100501
Title: Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes.
Journal: Nature immunology 20100501
Title: Imaging of atherosclerosis in apoliprotein e knockout mice: targeting of a folate-conjugated radiopharmaceutical to activated macrophages.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100501
Title: 'Twice-a-month' clodronate 200 mg IM: a new dosing regimen and improved therapy adherence in the treatment of postmenopausal osteoporosis.
Journal: Advances in therapy 20100501
Title: Kupffer cells participate in 2-butoxyethanol-induced liver hemangiosarcomas.
Journal: Toxicology 20100411
Title: 9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase.
Journal: The FEBS journal 20100401
Title: MRI shows clodronate-liposomes attenuating liver injury in rats with severe acute pancreatitis.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20100401
Title: Bisphosphonates in adjuvant treatment of early breast cancer.
Journal: Critical reviews in oncology/hematology 20100401
Title: Routine adjuvant use of bisphosphonates in breast cancer arguments in favour and against.
Journal: Critical reviews in oncology/hematology 20100401
Title: Evaluation of liposomal clodronate for treatment of malignant histiocytosis in dogs.
Journal: Cancer immunology, immunotherapy : CII 20100301
Title: Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20100301
Title: Brain perivascular macrophages and the sympathetic response to inflammation in rats after myocardial infarction.
Journal: Hypertension (Dallas, Tex. : 1979) 20100301
Title: Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy.
Journal: Cancer research 20100215
Title: Gastric and esophagus events before and during treatment of osteoporosis.
Journal: Calcified tissue international 20100201
Title: Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer.
Journal: European journal of cancer (Oxford, England : 1990) 20100201
Title: Rapid analysis of alkylphosphonate drugs by capillary zone electrophoresis using indirect ultraviolet detection.
Journal: Journal of separation science 20100201
Title: Clodronate liposomes: all sites of injection are not equal.
Journal: Hepatology (Baltimore, Md.) 20100201
Title: Kupffer cell activation is a causal factor for hepatic insulin resistance.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100101
Title: Phosphatase inhibitors with anti-angiogenic effect in vitro.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20100101
Title: Liposomes for specific depletion of macrophages from organs and tissues.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis.
Journal: BMC microbiology 20100101
Title: Apoptosis and autoimmunity induced by clodronate in systemic lupus erythematosus mononuclear circulating cells.
Journal: International journal of immunopathology and pharmacology 20100101
Title: Rejection of intradermally injected syngeneic tumor cells from mice by specific elimination of tumor-associated macrophages with liposome-encapsulated dichloromethylene diphosphonate, followed by induction of CD11b(+)/CCR3(-)/Gr-1(-) cells cytotoxic against the tumor cells.
Journal: Cancer immunology, immunotherapy : CII 20091201
Title: Can fall risk be incorporated into fracture risk assessment algorithms: a pilot study of responsiveness to clodronate.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20091201
Title: Further analysis of the survival benefit of clodronate.
Journal: Cancer biology & therapy 20091201
Title: Central neuroinvasion and demyelination by inflammatory macrophages after peripheral virus infection is controlled by SHP-1.
Journal: Viral immunology 20091201
Title: Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.
Journal: Biochimica et biophysica acta 20091101
Title: Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands.
Journal: The American journal of pathology 20091101
Title: Effects of liposome clodronate on renal leukocyte populations and renal fibrosis in murine obstructive nephropathy.
Journal: Journal of pharmacological sciences 20091101
Title: Fate of endothelialized modular constructs implanted in an omental pouch in nude rats.
Journal: Tissue engineering. Part A 20091001
Title: How T-cell-dependent and -independent challenges access the brain: vascular and neural responses to bacterial lipopolysaccharide and staphylococcal enterotoxin B.
Journal: Brain, behavior, and immunity 20091001
Title: Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control.
Journal: European journal of immunology 20091001
Title: Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm.
Journal: The American journal of pathology 20091001
Title: Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice.
Journal: PLoS pathogens 20091001
Title: The alpha,alpha-difluorinated phosphonate L-pSer-analogue: an accessible chemical tool for studying kinase-dependent signal transduction.
Journal: Chemistry & biology 20090925
Title: Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials.
Journal: The Lancet. Oncology 20090909
Title: Elevated endogenous surfactant reduces inflammation in an acute lung injury model.
Journal: Experimental lung research 20090901
Title: c-Jun terminal kinase-2 gene deleted mice overexpress hemeoxygenase-1 and are protected from hepatic ischemia reperfusion injury.
Journal: Transplantation 20090815
Title: Clodronate-induced cell apoptosis in human thyroid carcinoma is mediated via the P2 receptor signaling pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20090801
Title: TLR9-dependent systemic interferon-beta production by intravenous injection of plasmid DNA/cationic liposome complex in mice.
Journal: The journal of gene medicine 20090801
Title: Intra-articular clodronate for the treatment of knee osteoarthritis: dose ranging study vs hyaluronic acid.
Journal: Rheumatology (Oxford, England) 20090701
Title: Adjuvant bisphosphonates in breast cancer: are we witnessing the emergence of a new therapeutic strategy?
Journal: European journal of cancer (Oxford, England : 1990) 20090701
Title: Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice.
Journal: The Journal of clinical investigation 20090701
Title: Role of macrophages in the development of pancreatic islet injury in spontaneously diabetic torii rats.
Journal: Experimental animals 20090701
Title: Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro.
Journal: British journal of pharmacology 20090601
Title: Opposite roles of CCR2 and CX3CR1 macrophages in alkali-induced corneal neovascularization.
Journal: Cornea 20090601
Title: Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated.
Journal: Cancer research 20090601
Title: Role of lung-marginated monocytes in an in vivo mouse model of ventilator-induced lung injury.
Journal: American journal of respiratory and critical care medicine 20090515
Title: Ten-year fracture probability identifies women who will benefit from clodronate therapy--additional results from a double-blind, placebo-controlled randomised study.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20090501
Title: Potential role of macrophages in experimental keratomycosis.
Journal: Investigative ophthalmology & visual science 20090501
Title: Macrophage depletion delays progression of neuropathic pain in diabetic animals.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090501
Title: Effect of depletion of monocytes/macrophages on early aortic valve lesion in experimental hyperlipidemia.
Journal: Cell and tissue research 20090501
Title: Necrotic actions of nitrogen-containing bisphosphonates and their inhibition by clodronate, a non-nitrogen-containing bisphosphonate in mice: potential for utilization of clodronate as a combination drug with a nitrogen-containing bisphosphonate.
Journal: Basic & clinical pharmacology & toxicology 20090501
Title: Efficacy of clodronate, pamidronate, and zoledronate in reducing morbidity and mortality in cancer patients with bone metastasis: a meta-analysis of randomized clinical trials.
Journal: Clinical therapeutics 20090501
Title: Weekly clodronate treatment prevents bone loss and vertebral fractures in women with subclinical Cushing's syndrome.
Journal: Journal of endocrinological investigation 20090501
Title: Effect of allyl alcohol on hepatic transporter expression: zonal patterns of expression and role of Kupffer cell function.
Journal: Toxicology and applied pharmacology 20090401
Title: Macrophage depletion in hypertensive rats accelerates development of cardiomyopathy.
Journal: Journal of cardiovascular pharmacology and therapeutics 20090301
Title: Alendronate augments interleukin-1beta release from macrophages infected with periodontal pathogenic bacteria through activation of caspase-1.
Journal: Toxicology and applied pharmacology 20090215
Title: Effect of macrophage depletion on viral DNA rebound following antiretroviral therapy in a murine model of AIDS (MAIDS).
Journal: Antiviral research 20090201
Title: Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia.
Journal: American journal of physiology. Lung cellular and molecular physiology 20090201
Title: Treating low- and medium-potency bisphosphonate-related osteonecrosis of the jaws with a protocol for the treatment of chronic suppurative osteomyelitis: report of 7 cases.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20090201
Title: Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model.
Journal: Neoplasia (New York, N.Y.) 20090201
Title: Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice.
Journal: Innate immunity 20090201
Title: Clinical application of bisphosphonates in implant dentistry: histomorphometric evaluation.
Journal: The International journal of periodontics & restorative dentistry 20090201
Title: Value of information and value of implementation: application of an analytic framework to inform resource allocation decisions in metastatic hormone-refractory prostate cancer.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101
Title: Regulation of liver hepcidin expression by alcohol in vivo does not involve Kupffer cell activation or TNF-alpha signaling.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090101
Title: WHO fracture risk calculator (FRAX) in the assessment of obese patients with osteoporosis.
Journal: Endokrynologia Polska 20090101
Title: RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro.
Journal: Arthritis research & therapy 20090101
Title: Clodronic acid formulations available in Europe and their use in osteoporosis: a review.
Journal: Clinical drug investigation 20090101
Title: Resident macrophages influence stem cell activity in the mammary gland.
Journal: Breast cancer research : BCR 20090101
Title: Clodronate combined with a surfactant (Tween 20) does not improve osseointegration: a rabbit immunohistomorphometric study.
Journal: International journal of immunopathology and pharmacology 20090101
Title: Tartrate-resistant acid phosphatase (TRAP) as a serum marker for bone resorption in breast cancer patients with bone metastases.
Journal: Clinical and experimental obstetrics & gynecology 20090101
Title: Efficacy of intramuscular clodronate in Complex Regional Pain Syndrome type I: description of a case located in the astragalus in a patient with psoriatic arthritis.
Journal: Acta bio-medica : Atenei Parmensis 20090101
Title: Immune-to-brain signalling: the role of cerebral CD163-positive macrophages.
Journal: Neuroscience letters 20081219
Title: Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo).
Journal: Journal of the neurological sciences 20081215
Title: Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis.
Journal: The Journal of infectious diseases 20081215
Title: The role of macrophage in the pathogenesis of chronic cyclosporine-induced nephropathy.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201
Title: Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: a long-term follow-up.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20081201
Title: Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom.
Journal: Toxicon : official journal of the International Society on Toxinology 20081201
Title: Vitamin D receptor gene polymorphisms predict acquired resistance to clodronate treatment in patients with Paget's disease of bone.
Journal: Calcified tissue international 20081201
Title: Influence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes.
Journal: Bioconjugate chemistry 20081201
Title: Effect of short-term macrophage depletion in the development of posterior capsule opacification in rodents.
Journal: The British journal of ophthalmology 20081101
Title: [Bisphosphonates for osseus invasion caused by bronchial carcinoma].
Journal: Deutsche medizinische Wochenschrift (1946) 20081101
Title: Postmenopausal osteoporosis. The role of intravenous bisphosphonates.
Journal: Advance for nurse practitioners 20081101
Title: Macrophage-independent T cell infiltration to the site of injury-induced brain inflammation.
Journal: Journal of neuroimmunology 20081015
Title: Platelet dynamics in the early phase of postischemic liver in vivo.
Journal: The Journal of surgical research 20081001
Title: Vertebral fracture assessment (VFA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20081001
Title: Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord.
Journal: Neuropharmacology 20081001
Title: Bacterial entry to the splenic white pulp initiates antigen presentation to CD8+ T cells.
Journal: Immunity 20080919
Title: Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080917
Title: Ten-year follow-up of 3 years of oral adjuvant clodronate therapy shows significant prevention of osteoporosis in early-stage breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080910
Title: Investigation into the role of tumor-associated macrophages in the antitumor activity of Doxil.
Journal: Pharmaceutical research 20080801
Title: Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080801
Title: Depletion of resident alveolar macrophages does not prevent Fas-mediated lung injury in mice.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080801
Title: Liposomes for targeting of antigens and drugs: immunoadjuvant activity and liposome-mediated depletion of macrophages.
Journal: Journal of drug targeting 20080801
Title: Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages.
Journal: Cancer science 20080801
Title: Tumoricidal activity of high-dose tumor necrosis factor-alpha is mediated by macrophage-derived nitric oxide burst and permanent blood flow shutdown.
Journal: International journal of cancer 20080715
Title: A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition.
Journal: Bioorganic & medicinal chemistry 20080715
Title: Differential effects of GdCl3- or MDP treatment on rat liver microcirculation and gene expression in the hepatic non-parenchymal cell fraction in LPS shock.
Journal: Microcirculation (New York, N.Y. : 1994) 20080701
Title: Macrophage depletion diminishes implant-wear-induced inflammatory osteolysis in a mouse model.
Journal: Journal of biomedical materials research. Part A 20080615
Title: Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: implications for renal safety.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080601
Title: Functional and phenotypic characteristics of testicular macrophages in experimental autoimmune orchitis.
Journal: The Journal of pathology 20080601
Title: The investigation of macrophage infiltration in the early phase of ischemic acute renal failure in mice.
Journal: The Korean journal of internal medicine 20080601
Title: Macrophage colony-stimulating factor is indispensable for repopulation and differentiation of Kupffer cells but not for splenic red pulp macrophages in osteopetrotic (op/op) mice after macrophage depletion.
Journal: Cell and tissue research 20080501
Title: Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080501
Title: Clodronate inhibits angiogenesis in vitro and in vivo.
Journal: Oncology reports 20080501
Title: Gut ischemia/reperfusion induced acute lung injury is an alveolar macrophage dependent event.
Journal: The Journal of trauma 20080501
Title: The fate of MAb-targeted Cd(125m)Te/ZnS nanoparticles in vivo.
Journal: Nuclear medicine and biology 20080501
Title: Protective effects of elevated endogenous surfactant pools to injurious mechanical ventilation.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080401
Title: Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response.
Journal: Hypertension (Dallas, Tex. : 1979) 20080401
Title: Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma.
Journal: Molecular cancer therapeutics 20080401
Title: Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth.
Journal: Anti-cancer drugs 20080401
Title: Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: definition and management of the risk related to zoledronic acid.
Journal: Clinical lymphoma & myeloma 20080401
Title: Abdominal aortic calcification detected on lateral spine images from a bone densitometer predicts incident myocardial infarction or stroke in older women.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080301
Title: Relative contribution of direct and indirect allorecognition in developing tolerance after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080301
Title: The role of macrophages in early healing of a tendon graft in a bone tunnel.
Journal: The Journal of bone and joint surgery. American volume 20080301
Title: [Osteonecrosis of the jaw developing during bisphosphonate treatment].
Journal: Magyar onkologia 20080301
Title: Prolonged islet allograft survival in diabetic mice upon macrophage depletion by clodronate-loaded erythrocytes.
Journal: Transplantation 20080227
Title: Interaction between macrophages, TGF-beta1, and the COX-2 pathway during the inflammatory phase of skeletal muscle healing after injury.
Journal: Journal of cellular physiology 20080201
Title: Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue.
Journal: Neoplasia (New York, N.Y.) 20080201
Title: Effects of depletion of neutrophils or macrophages on the inflammatory response induced by metalloelastase (MMP-12) in mice airways.
Journal: European journal of pharmacology 20080128
Title: Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: role of transglutaminases.
Journal: Journal of vascular research 20080101
Title: Macrophage involvement in the kidney repair phase after ischaemia/reperfusion injury.
Journal: The Journal of pathology 20080101
Title: Effects of Kupffer cell-depletion on Concanavalin A-induced hepatitis.
Journal: Cellular immunology 20080101
Title: Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model.
Journal: Anticancer research 20080101
Title: Cost-effectiveness of oral clodronate compared with oral ibandronate, intravenous zoledronate or intravenous pamidronate in breast cancer patients.
Journal: The Journal of international medical research 20080101
Title: Application of UV-derivative spectrophotometry for determination of some bisphosphonates drugs in pharmaceutical formulations.
Journal: Acta poloniae pharmaceutica 20080101
Title: Are new-generation bisphosphonates effective for the inhibition of calcium oxalate stone formation in a rat model?
Journal: Urologia internationalis 20080101
Title: Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis.
Journal: Cancer science 20071201
Title: Antiangiogenic effects of bisphosphonates on laser-induced choroidal neovascularization in mice.
Journal: Investigative ophthalmology & visual science 20071201
Title: Evidence based medicine and effective interventions of pharmacological therapy for the prevention of osteoporotic fractures.
Journal: Minerva endocrinologica 20071201
Title: Different responses of macrophages in retinal ganglion cell survival after acute ocular hypertension in rats with different autoimmune backgrounds.
Journal: Experimental eye research 20071101
Title: The use of bone markers in a 6-week study to assess the efficacy of oral clodronate in patients with metastatic bone disease.
Journal: Calcified tissue international 20071101
Title: Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis.
Journal: Journal of hepatology 20071001
Title: Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice.
Journal: American journal of physiology. Cell physiology 20071001
Title: Alveolar macrophages are necessary for the systemic inflammation of acute alveolar hypoxia.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20071001
Title: A double-blind placebo-controlled study of intravenous clodronate for prevention of steroid-induced bone loss in inflammatory bowel disease.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20071001
Title: Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Journal: The Journal of clinical investigation 20071001
Title: Development and application of a high-performance liquid chromatography-mass spectrometry method to determine alendronate in human urine.
Journal: Journal of chromatography. A 20070810
Title: Alveolar macrophage depletion is associated with increased surfactant pool sizes in adult rats.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070801
Title: Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft.
Journal: The Journal of investigative dermatology 20070801
Title: Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP.
Journal: Bioorganic & medicinal chemistry letters 20070801
Title: PI3K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury.
Journal: The European journal of neuroscience 20070801
Title: Reduction in alveolar macrophages attenuates acute ventilator induced lung injury in rats.
Journal: Intensive care medicine 20070701
Title: Oral sodium clodronate induced osteonecrosis of the jaw in a patient with myeloma.
Journal: European journal of haematology 20070701
Title: Murine alveolar macrophages limit replication of vaccinia virus.
Journal: Virology 20070620
Title: Meta-analysis of clodronate and breast cancer survival.
Journal: British journal of cancer 20070618
Title: Bisphosphonates: are they standard of care for the treatment of breast cancer?
Journal: British journal of cancer 20070618
Title: A 4-year treatment with clodronate plus calcium and vitamin D supplements does not improve bone mass in primary biliary cirrhosis.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20070601
Title: Oral sodium clodronate for nonmetastatic prostate cancer--results of a randomized double-blind placebo-controlled trial: Medical Research Council PR04 (ISRCTN61384873).
Journal: Journal of the National Cancer Institute 20070516
Title: Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20070501
Title: Pertussis toxin targets airway macrophages to promote Bordetella pertussis infection of the respiratory tract.
Journal: Infection and immunity 20070401
Title: [Relevance of bisphosphonate long-term therapy in radiation therapy of endosteal jaw metastases].
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20070401
Title: Amino-bisphosphonates decrease hTERT gene expression in breast cancer in vitro.
Journal: Aging clinical and experimental research 20070401
Title: Comparative study of the protective effect of different intravenous bisphosphonates on the decrease in bone mineral density in patients submitted to radical prostatectomy undergoing androgen deprivation therapy. A prospective open-label controlled study.
Journal: International journal of urology : official journal of the Japanese Urological Association 20070401
Title: Macrophage depletion in the murine olfactory epithelium leads to increased neuronal death and decreased neurogenesis.
Journal: The Journal of comparative neurology 20070310
Title: Macrophage depletion alters the blood-nerve barrier without affecting Schwann cell function after neural injury.
Journal: Journal of neuroscience research 20070301
Title: Severe osteomyelitis of the mandible associated with the use of non-nitrogen-containing bisphosphonate (disodium clodronate): report of a case.
Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20070301
Title: New multifunctional anti-osteolytic releasing bioabsorbable implant.
Journal: The Journal of craniofacial surgery 20070301
Title: Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis.
Journal: Journal of the National Cancer Institute 20070221
Title: Differential effects of bisphosphonates on breast cancer cell lines.
Journal: Cancer letters 20070208
Title: Histidine decarboxylase-stimulating and inflammatory effects of alendronate in mice: involvement of mevalonate pathway, TNFalpha, macrophages, and T-cells.
Journal: International immunopharmacology 20070201
Title: [Experimental study for thrombocytopenic purpura therapy by targeting macrophages in liver and spleen].
Journal: Zhongguo shi yan xue ye xue za zhi 20070201
Title: Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: results of a double-blind, placebo-controlled randomized study.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070101
Title: Reduction of renal fibrosis as a result of liposome encapsulated clodronate induced macrophage depletion after unilateral ureteral obstruction in rats.
Journal: Nephron. Experimental nephrology 20070101
Title: C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070101
Title: Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Journal: Arthritis and rheumatism 20070101
Title: Clinical usefulness of bisphosphonates in oncology: treatment of bone metastases, antitumoral activity and effect on bone resorption markers.
Journal: The International journal of biological markers 20070101
Title: Clodronic acid in the treatment of postmenopausal osteoporosis.
Journal: Clinical drug investigation 20070101
Title: Pharmacologic modulation of clodronate in local therapy of periodontal and implant inflammation.
Journal: International journal of immunopathology and pharmacology 20070101
Title: Effect of bisphosphonates on nitric oxide production by inflammatory activated chondrocytes.
Journal: Clinical and experimental rheumatology 20070101
Title: Synthesis of methylene- and difluoromethylenephosphonate analogues of uridine-4-phosphate and 3-deazauridine-4-phosphate.
Journal: The Journal of organic chemistry 20061208
Title: Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury.
Journal: American journal of physiology. Lung cellular and molecular physiology 20061201
Title: Tumor necrosis factor alpha and macrophages in the brain of herpes simplex virus type 1-infected BALB/c mice.
Journal: Journal of neurovirology 20061201
Title: Postoperative clodronate decreases prosthetic migration: 4-year follow-up of a randomized radiostereometric study of 50 total knee patients.
Journal: Acta orthopaedica 20061201
Title: Alveolar macrophage activation is a key initiation signal for acute lung ischemia-reperfusion injury.
Journal: American journal of physiology. Lung cellular and molecular physiology 20061101
Title: A new model for limbal transplantation using E-GFP for follow-up of transplant survival.
Journal: Experimental eye research 20061101
Title: Intracorneal instillation of latex beads induces macrophage-dependent protection against Acanthamoeba keratitis.
Journal: Investigative ophthalmology & visual science 20061101
Title: Phase II trial evaluating the palliative benefit of second-line zoledronic acid in breast cancer patients with either a skeletal-related event or progressive bone metastases despite first-line bisphosphonate therapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061020
Title: Synthesis of bisphosphonate derivatives of ATP by T4 RNA ligase.
Journal: FEBS letters 20061016
Title: Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs.
Journal: Experimental hematology 20061001
Title: Antioxidant effect of bisphosphonates and simvastatin on chondrocyte lipid peroxidation.
Journal: Biochemical and biophysical research communications 20060922
Title: Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin.
Journal: Archives of toxicology 20060901
Title: Targeting study of gelatin adsorbed clodronate in reticuloendothelial system and its potential application in immune thrombocytopenic purpura of rat model.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20060828
Title: Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach.
Journal: British journal of cancer 20060807
Title: Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Clodronate inhibits PGE(2) production in compressed periodontal ligament cells.
Journal: Journal of dental research 20060801
Title: Potential role of microglia in retinal blood vessel formation.
Journal: Investigative ophthalmology & visual science 20060801
Title: Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation.
Journal: The Journal of clinical investigation 20060801
Title: Clodronate alleviates cachexia and prolongs survival in nude mice xenografted with an anaplastic thyroid carcinoma cell line.
Journal: The Journal of endocrinology 20060801
Title: Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII.
Journal: Circulation research 20060707
Title: Effects of alveolar macrophage depletion on liposomal vaccine protection against respiratory syncytial virus (RSV).
Journal: Clinical and experimental immunology 20060701
Title: Macrophages are vital in spontaneous intraocular tumor eradication.
Journal: Investigative ophthalmology & visual science 20060701
Title: Effects of macrophage inducible nitric oxide synthase in murine septic lung injury.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060601
Title: Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060601
Title: Fracture prevention in postmenopausal women.
Journal: Clinical evidence 20060601
Title: Mutual augmentation of the induction of the histamine-forming enzyme, histidine decarboxylase, between alendronate and immuno-stimulants (IL-1, TNF, and LPS), and its prevention by clodronate.
Journal: Toxicology and applied pharmacology 20060515
Title: Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis.
Journal: Molecular pharmacology 20060501
Title: Antigen sensitization modulates alveolar macrophage functions in an asthma model.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060501
Title: Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease.
Journal: Blood 20060415
Title: Liver-stage development of Plasmodium falciparum, in a humanized mouse model.
Journal: The Journal of infectious diseases 20060401
Title: Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors.
Journal: Bioorganic & medicinal chemistry 20060301
Title: Kupffer cells abrogate cholestatic liver injury in mice.
Journal: Gastroenterology 20060301
Title: Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.
Journal: Immunity 20060201
Title: Lipid emulsions potently increase transgene expression in hepatocytes after adenoviral transfer.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20060101
Title: The use of bisphosphonates in palliative treatment of bone metastases in a terminally ill, oncological elderly population.
Journal: Archives of gerontology and geriatrics 20060101
Title: Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026].
Journal: Breast cancer research : BCR 20060101
Title: Bisphosphonate pretreatment attenuates hungry bone syndrome postoperatively in subjects with primary hyperparathyroidism.
Journal: Journal of bone and mineral metabolism 20060101
Title: Effects of bisphosphonates on prostaglandin E2 and thromboxane B2 production in human whole blood and monocytes stimulated by lipopolysaccharide and A23187.
Journal: Methods and findings in experimental and clinical pharmacology 20060101
Title: Cartilage oligomeric matrix protein (COMP) is modified by intra-articular liposomal clodronate in an experimental model of arthritis.
Journal: Clinical and experimental rheumatology 20060101
Title: The incidence of jaw osteonecrosis in multiple myeloma patients treated with bisphosphonates.
Journal: Acta poloniae pharmaceutica 20060101
Title: Osteoclast responses to lipopolysaccharide, parathyroid hormone and bisphosphonates in neonatal murine calvaria analyzed by laser scanning confocal microscopy.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20051201
Title: Acute renal effects of intravenous bisphosphonates in the rat.
Journal: Basic & clinical pharmacology & toxicology 20051201
Title: Macrophages are involved in hexachlorobenzene-induced adverse immune effects.
Journal: Toxicology and applied pharmacology 20051115
Title: Aging of red blood cells and impaired erythropoiesis following prolonged administration of dichloromethylene diphosphonate containing liposomes in rats.
Journal: European journal of haematology 20051101
Title: Intermittent intramuscular clodronate therapy: a valuable option for older osteoporotic women.
Journal: Age and ageing 20051101
Title: S0307. Phase III trial of bisphosphonates as adjuvant therapy for primary breast cancer.
Journal: Clinical advances in hematology & oncology : H&O 20051101
Title: Real-time in vivo imaging of apoptotic cell membrane changes in monocytes and macrophages.
Journal: Apoptosis : an international journal on programmed cell death 20051001
Title: Pilot studies of the effect of zoledronic acid (Zometa) on tumor-derived cells ex vivo in the ATP-based tumor chemosensitivity assay.
Journal: Anti-cancer drugs 20051001
Title: Comparative appraisal of clodronate, aspirin and dexamethasone as agents reducing alendronate-induced inflammation in a murine model.
Journal: Basic & clinical pharmacology & toxicology 20051001
Title: A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis.
Journal: European journal of immunology 20051001
Title: Serum tartrate-resistant acid phosphatase 5b in monitoring bisphosphonate treatment with clodronate: a comparison with urinary N-terminal telopeptide of type I collagen and serum type I procollagen amino-terminal propeptide.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20050901
Title: Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells.
Journal: Clinical and experimental immunology 20050901
Title: Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2.
Journal: Journal of neuropathology and experimental neurology 20050901
Title: Bisphosphonates decrease telomerase activity and hTERT expression in MCF-7 breast cancer cells.
Journal: Molecular and cellular endocrinology 20050830
Title: Three-year oral clodronate treatment does not impair mineralization of newly formed bone--a histomorphometric study.
Journal: Calcified tissue international 20050801
Title: Role of gut macrophages in mice orally contaminated with scrapie or BSE.
Journal: International journal of pharmaceutics 20050725
Title: The effect of clodronate on the integrity and viability of rat small intestine in vitro-a comparison with EDTA.
Journal: Biological & pharmaceutical bulletin 20050701
Title: Inhibition of inflammatory and bone-resorption-inhibitory effects of alendronate by etidronate.
Journal: Calcified tissue international 20050601
Title: Iron- and inflammation-induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo.
Journal: Hepatology (Baltimore, Md.) 20050501
Title: Bisphosphonates in breast cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050501
Title: The role of bisphosphonates in the treatment of prostate cancer.
Journal: BJU international 20050501
Title: The issue of renal safety of zoledronic acid from a nephrologist's point of view.
Journal: The oncologist 20050501
Title: 'Safety and convenience of a 15-minute infusion of zoledronic acid': not so safe.
Journal: The oncologist 20050501
Title: The reactive D-glucopyranose moiety of streptozotocin is responsible for activation of macrophages and subsequent stimulation of CD8+ T cells.
Journal: Chemical research in toxicology 20050501
Title: Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages.
Journal: American journal of physiology. Renal physiology 20050401
Title: Bacterial adhesion to bisphosphonate coated hydroxyapatite.
Journal: Journal of materials science. Materials in medicine 20050401
Title: Should oral bisphosphonates be standard of care in women with early breast cancer?
Journal: Breast cancer research and treatment 20050401
Title: Clodronate in the prevention and treatment of skeletal metastasis.
Journal: Expert review of anticancer therapy 20050401
Title: Suppression of macrophage infiltration into the conjunctiva by clodronate liposomes in experimental immune-mediated blepharoconjunctivitis.
Journal: Cell biology international 20050401
Title: Clodronate treatment influences MMP-2 associated outcome in node positive breast cancer.
Journal: Breast cancer research and treatment 20050301
Title: [Pharmacological treatment of osteitis deformans (Paget's bone disease)].
Journal: Ugeskrift for laeger 20050227
Title: Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation.
Journal: Journal of leukocyte biology 20050201
Title: Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial.
Journal: Head & neck 20050201
Title: Evolving role of bisphosphonates in women undergoing treatment for localized and advanced breast cancer.
Journal: Clinical breast cancer 20050201
Title: Macrophage depletion induced by clodronate-loaded erythrocytes.
Journal: Journal of drug targeting 20050201
Title: [Effect of glucocorticoids on bone mineral density in patients with idiopathic thrombocytopenic purpura].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20050201
Title: [Diphosphonates in solid malignant tumors].
Journal: Ugeskrift for laeger 20050124
Title: Effective parenteral clodronate treatment of a child with severe juvenile idiopathic osteoporosis.
Journal: European journal of pediatrics 20050101
Title: Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats.
Journal: Journal of hepatology 20050101
Title: Depletion of alveolar macrophages by clodronate-liposomes aggravates ischemia-reperfusion injury of the lung.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050101
Title: The role of Kupffer cells after major liver surgery.
Journal: JPEN. Journal of parenteral and enteral nutrition 20050101
Title: The role of bisphosphonates in the management of advanced cancer with a focus on non-small-cell lung cancer. Part 1: Mechanisms of action, role of biomarkers and preclinical applications.
Journal: Oncology 20050101
Title: [The effects of clodronate for the pain treatment of bone metastasis due to prostate cancer].
Journal: Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20050101
Title: Macrophage depletion prevents anti-graft antibody production and results in long-term survival in xenotransplantation.
Journal: Transplantation proceedings 20050101
Title: Adjuvant clodronate in breast cancer.
Journal: Acta oncologica (Stockholm, Sweden) 20050101
Title: Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate.
Journal: Experimental lung research 20050101
Title: [Association between primary hyperparathyroidism and Paget's disease. Report of a case].
Journal: Anales otorrinolaringologicos ibero-americanos 20050101
Title: [Zoledronic acid and bone pathology in the course of neoplasia. Part I].
Journal: Tumori 20050101
Title: Cost analysis of secondary prophylaxis with oral clodronate versus pamidronate in metastatic breast cancer patients.
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20041201
Title: Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells.
Journal: British journal of cancer 20041101
Title: [Synthesis of phosphonic acid and phosphinic acid derivatives for development of biologically active compounds].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041101
Title: Enhanced engraftment of human cells in RAG2/gammac double-knockout mice after treatment with CL2MDP liposomes.
Journal: Experimental hematology 20041101
Title: Clodronate inhibits the secretion of proinflammatory cytokines and NO by isolated microglial cells and reduces the number of proliferating glial cells in excitotoxically injured organotypic hippocampal slice cultures.
Journal: Experimental neurology 20041001
Title: The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus anthracis spores.
Journal: Microbial pathogenesis 20041001
Title: Bisphosphonates in the treatment of skeletal metastases.
Journal: Seminars in oncology 20041001
Title: Effects of local administration of clodronate on orthodontic tooth movement and root resorption in rats.
Journal: European journal of orthodontics 20041001
Title: Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity.
Journal: The American journal of medicine 20040915
Title: Risedronate and pamidronate treatment in the clinical management of patients with severe Paget's disease of bone and acquired resistance to bisphosphonates.
Journal: Calcified tissue international 20040901
Title: Short-term intermittent intravenous clodronate in the prevention of bone loss related to chemotherapy-induced ovarian failure.
Journal: Breast cancer research and treatment 20040901
Title: Toxicity and antineoplastic effect of (24R)-1,24-dihydroxyvitamin D3 (PRI-2191).
Journal: Steroids 20040901
Title: In vitro toxicity of bisphosphonates on human neuroblastoma cell lines.
Journal: Anti-cancer drugs 20040901
Title: Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells.
Journal: British journal of cancer 20040816
Title: Tamoxifen treatment reverses the adverse effects of chemotherapy-induced ovarian failure on serum lipids.
Journal: British journal of cancer 20040802
Title: Adoptive transfer of alveolar macrophages abrogates bronchial hyperresponsiveness.
Journal: American journal of respiratory cell and molecular biology 20040701
Title: Prevention and management of osteoporosis in women with breast cancer and men with prostate cancer.
Journal: Current oncology reports 20040701
Title: Tissue monocytes/macrophages in inflammation: hyperalgesia versus opioid-mediated peripheral antinociception.
Journal: Anesthesiology 20040701
Title: Macrophages play a role in the early phase of corneal allograft rejection in rats.
Journal: Transplantation 20040615
Title: Hypocalcaemia after intravenous bisphosphonate: adjuvant bisphosphonate is not currently accepted practice.
Journal: BMJ (Clinical research ed.) 20040612
Title: Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism.
Journal: Experimental eye research 20040601
Title: Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040601
Title: Kupffer cell-depleted rats have a diminished acute-phase response following major liver resection.
Journal: Shock (Augusta, Ga.) 20040601
Title: Role of macrophages in a mouse model of postoperative MRSA enteritis.
Journal: The Journal of surgical research 20040515
Title: Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040501
Title: Clodronate reduces vertebral fracture risk in women with postmenopausal or secondary osteoporosis: results of a double-blind, placebo-controlled 3-year study.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040501
Title: Peripheral macrophage depletion reduces central nervous system parasitism and damage in Trypanosoma cruzi-infected suckling rats.
Journal: Journal of neuroimmunology 20040401
Title: Macrophage depletion reduces monocyte chemotactic protein-1 and transforming growth factor-beta1 in healing rat vein grafts.
Journal: Journal of vascular surgery 20040401
Title: Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate.
Journal: Experimental lung research 20040301
Title: Effects of clodronate and alendronate on local and systemic changes in bone metabolism in rats with adjuvant arthritis.
Journal: Inflammation 20040201
Title: Determination of disodium clodronate in human plasma and urine using gas-chromatography-nitrogen-phosphorous detections: validation and application in pharmacokinetic study.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040105
Title: Effects of weekly administrations of alendronate+clodronate on young mouse tibia: localized action at the proximal growth plate.
Journal: Calcified tissue international 20040101
Title: Utilization of palliative radiotherapy for breast cancer patients with bone metastases treated with bisphosphonates-Toronto Sunnybrook Regional Cancer Centre experience.
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20040101
Title: Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.
Journal: Arthritis and rheumatism 20040101
Title: Safety and convenience of a 15-minute infusion of zoledronic acid.
Journal: The oncologist 20040101
Title: A tolerability and pharmacokinetic study of a new injectable formulation of disodium clodronate in healthy female volunteers.
Journal: European journal of drug metabolism and pharmacokinetics 20040101
Title: Antiresorption therapy and reduction in fracture susceptibility in the osteoporotic elderly patient: open study.
Journal: European review for medical and pharmacological sciences 20040101
Title: Effects of clodronate on cancer growth and Ca2+ signaling of human thyroid carcinoma cell lines.
Journal: Anticancer research 20040101
Title: Use of 18O3-clodronate as an internal standard for the quantitative analysis of clodronate in human plasma by gas chromatography/electron ionisation mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Involvement of CD8+ T-cells in exacerbation of corneal scarring in mice.
Journal: Current eye research 20040101
Title: Use of bisphosphonates can dramatically improve pain in advanced hormone-refractory prostate cancer patients.
Journal: Prostate cancer and prostatic diseases 20040101
Title: Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients.
Journal: Acta oncologica (Stockholm, Sweden) 20040101
Title: Clodronate : a review of its use in the prevention of bone metastases and the management of skeletal complications associated with bone metastases in patients with breast cancer.
Journal: Drugs & aging 20040101
Title: Macrophage derived signalling regulates negatively the megakaryocyte compartment.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20040101
Title: [Expanding the possibilities of using biphosphonates for prophylaxis and treatment of osteal complications in malignant metastasis].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101
Title: [AIOM Conference 2004. Endocrine therapy and management of patients with bone metastasis of breast cancer].
Journal: Tumori 20040101
Title: Effects of macrophage depletion on peritoneal inflammation in swiss mice, edible frogs and goldfish.
Journal: Folia biologica 20040101
Title: Minor effect of depletion of resident macrophages from peritoneal cavity on resistance of common carp Cyprinus carpio to blood flagellates.
Journal: Diseases of aquatic organisms 20031203
Title: Bisphosphonates to prevent skeletal complications in men with metastatic prostate cancer.
Journal: The Journal of urology 20031201
Title: Levels and molecular forms of MMP-7 (matrilysin-1) and MMP-8 (collagenase-2) in diseased human peri-implant sulcular fluid.
Journal: Journal of periodontal research 20031201
Title: A single bisphosphonate infusion is associated with improved functional capacity in elderly subjects with primary hyperparathyroidism.
Journal: Aging clinical and experimental research 20031201
Title: Use of dichloromethylene bisphosphonate (Cl2MBP) to deplete macrophage function in the chicken.
Journal: British poultry science 20031201
Title: Bisphosphonate therapy in the oncology setting.
Journal: Expert opinion on emerging drugs 20031101
Title: Oral clodronate therapy for hypercalcemia related to extensive subcutaneous fat necrosis in a newborn.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20031101
Title: Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt.
Journal: The Journal of biological chemistry 20031031
Title: A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice.
Journal: Blood 20031001
Title: Oral clodronate as treatment of osteogenesis imperfecta.
Journal: Archives of disease in childhood 20031001
Title: Do peritoneal macrophages play an essential role in the progression of acute pancreatitis in rats?
Journal: Pancreas 20031001
Title: The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro.
Journal: Anti-cancer drugs 20031001
Title: Long-term analgesic effect of clodronate in rodents.
Journal: Bone 20031001
Title: Effects of 4-year treatment with once-weekly clodronate on prevention of corticosteroid-induced bone loss and fractures in patients with arthritis: evaluation with dual-energy X-ray absorptiometry and quantitative ultrasound.
Journal: Bone 20031001
Title: Efficacy of disodium-clodronate in the management of joint pain in rheumatoid arthritis. Six months open study.
Journal: Minerva medica 20031001
Title: Regulation of MMP-9 (gelatinase B) in activated human monocyte/macrophages by two different types of bisphosphonates.
Journal: Life sciences 20030926
Title: Role of macrophages in the generation of circulating blood nucleosomes from dead and dying cells.
Journal: Blood 20030915
Title: Clodronate stimulates osteoblast differentiation in ST2 and MC3T3-E1 cells and rat organ cultures.
Journal: European journal of pharmacology 20030905
Title: Bisphosphonates in prostate cancer: where are we and where should we go?
Journal: Journal of the National Cancer Institute 20030903
Title: Clinical trials test bisphosphonates in hormone-sensitive prostate cancer.
Journal: Journal of the National Cancer Institute 20030903
Title: A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial).
Journal: Journal of the National Cancer Institute 20030903
Title: Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901
Title: Safety of subcutaneous clodronate and efficacy in hypercalcemia of malignancy: a novel route of administration.
Journal: Journal of pain and symptom management 20030901
Title: Mechanism of action of bisphosphonates.
Journal: Current osteoporosis reports 20030901
Title: Effects of various absorption enhancers on transport of clodronate through Caco-2 cells.
Journal: International journal of pharmaceutics 20030811
Title: Expression of fractalkine in the rat testis: molecular cloning of a novel alternative transcript of its gene that is differentially regulated by pro-inflammatory cytokines.
Journal: Molecular human reproduction 20030801
Title: Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030801
Title: Macrophage depletion inhibits experimental choroidal neovascularization.
Journal: Investigative ophthalmology & visual science 20030801
Title: Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization.
Journal: Investigative ophthalmology & visual science 20030801
Title: Bisphosphonate resistance in Paget's disease of bone.
Journal: Arthritis and rheumatism 20030801
Title: Using of disodium clodronate on DSO patients.
Journal: International journal of oral and maxillofacial surgery 20030801
Title: Injectable bisphosphonates in the treatment of postmenopausal osteoporosis.
Journal: Aging clinical and experimental research 20030801
Title: Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balance.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030715
Title: Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate.
Journal: The Journal of surgical research 20030601
Title: Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB/c mice.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030515
Title: Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats.
Journal: Xenotransplantation 20030501
Title: Adhesion molecule expression in local-macrophage-depleted rats bearing orthotopic corneal allografts.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030501
Title: The bisphosphonate clodronate depletes microglial cells in excitotoxically injured organotypic hippocampal slice cultures.
Journal: Experimental neurology 20030501
Title: Cellular uptake and metabolism of clodronate and its derivatives in Caco-2 cells: a possible correlation with bisphosphonate-induced gastrointestinal side-effects.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030501
Title: Aetiology of bone disease and the role of bisphosphonates in multiple myeloma.
Journal: The Lancet. Oncology 20030501
Title: Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate.
Journal: The Journal of surgical research 20030501
Title: Clodronate induced uveitis.
Journal: Annals of the rheumatic diseases 20030401
Title: Macrophage depletion following liposomal-encapsulated clodronate (LIP-CLOD) injection enhances megakaryocytopoietic and thrombopoietic activities in mice.
Journal: British journal of haematology 20030401
Title: Determination of clodronate content in liposomal formulation by capillary zone electrophoresis.
Journal: Journal of pharmaceutical and biomedical analysis 20030401
Title: Intravenous treatment with liposome-encapsulated dichloromethylene bisphosphonate (Cl2MBP) suppresses nitric oxide production and reduces genetic resistance to Marek's disease.
Journal: Avian pathology : journal of the W.V.P.A 20030401
Title: Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors.
Journal: Blood 20030301
Title: Long-term administration of clodronate does not prevent fracture healing in rats.
Journal: Clinical orthopaedics and related research 20030301
Title: [A patient with gastric cancer complicated with severe DIC and multiple bone metastasis showing a high response to combination of TS-1 and CDDP].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030301
Title: Biodegradable microspheres targeting mucosal immune-regulating cells: new approach for treatment of inflammatory bowel disease.
Journal: Journal of gastroenterology 20030301
Title: Clodronate stimulates bone formation as well as inhibits bone resorption and increases bone mineral density in rats fed a low-calcium diet.
Journal: Journal of medical and dental sciences 20030301
Title: Clodronate treatment of established bone loss in cardiac recipients: a randomized study.
Journal: Transplantation 20030215
Title: Current and future status of adjuvant therapy for breast cancer.
Journal: Cancer 20030201
Title: Antagonistic effects of different classes of bisphosphonates in osteoclasts and macrophages in vitro.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030201
Title: Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice.
Journal: Digestive diseases and sciences 20030201
Title: Effect of local macrophage depletion on cellular immunity and tolerance evoked by corneal allografts.
Journal: Current eye research 20030201
Title: Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model.
Journal: Blood 20030115
Title: Characterization of an in vitro model of calcification in retinal pigmented epithelial cells.
Journal: Journal of atherosclerosis and thrombosis 20030101
Title: Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous biphosphonates.
Journal: Clinical and experimental rheumatology 20030101
Title: Biochemical markers of bone turnover, serum levels of interleukin-6/interleukin-6 soluble receptor and bisphosphonate treatment in Erdheim-Chester disease.
Journal: Clinical and experimental rheumatology 20030101
Title: Extended safety profile of oral clodronate after long-term use in primary breast cancer patients.
Journal: Drug safety 20030101
Title: Effect of elimination of donor Kupffer cells and/or recipient macrophages on acute rejection in liver transplantation.
Journal: Hepato-gastroenterology 20030101
Title: [The use of parenteral clodronate in elderly women with postmenopausal osteoporosis: compliance, effects on bone mineral density and on bone turnover].
Journal: Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20030101
Title: Effect of raloxifene and clodronate on bone density in postmenopausal osteoporotic women.
Journal: International journal of tissue reactions 20030101
Title: Should all adjuvant breast cancer patients receive a bisphosphonate?
Journal: Breast cancer research : BCR 20030101
Title: Quantitative ultrasound of bone and clodronate effects in thalassemia-induced osteoporosis.
Journal: Journal of bone and mineral metabolism 20030101
Title: [Prognostication of hematotoxicity for radio- and chemotherapy in patients with breast cancer].
Journal: Voprosy onkologii 20030101
Title: Clodronate as a single-dose intravenous infusion effectively provides short-term correction of malignant hypercalcemia.
Journal: Acta oncologica (Stockholm, Sweden) 20030101
Title: 'In vivo' depletion of macrophages by liposome-mediated 'suicide'.
Journal: Methods in enzymology 20030101
Title: APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021215
Title: Prevention of bone loss by clodronate in early postmenopausal women with vertebral osteopenia: a dose-finding study.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20021201
Title: Disease modifying and anti-nociceptive effects of the bisphosphonate, zoledronic acid in a model of bone cancer pain.
Journal: Pain 20021201
Title: Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice.
Journal: Chemical research in toxicology 20021201
Title: Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints.
Journal: American journal of clinical oncology 20021201
Title: Treatment of hypercalcemia of malignancy with bisphosphonates.
Journal: Seminars in oncology 20021201
Title: [Therapy for hormone-refractory prostate cancer].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201
Title: Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats.
Journal: Cancer research 20021115
Title: Bisphosphonates as adjuvant treatment for breast cancer.
Journal: BMJ (Clinical research ed.) 20021109
Title: Clodronate: mechanisms of action on bone remodelling and clinical use in osteometabolic disorders.
Journal: Expert opinion on pharmacotherapy 20021101
Title: [A questionnaire survey of tolerance and adverse effects of clodronate (Bonefos) in patients with multiple myeloma].
Journal: Vnitrni lekarstvi 20021101
Title: Bisphosphonates for RSDS and prostate cancer--more benefit then revealed!
Journal: Joint, bone, spine : revue du rhumatisme 20021001
Title: American Society of Clinical Oncology clinical practice guidelines: the role of bisphosphonates in multiple myeloma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020901
Title: Clodronate inhibits adrenocortical cell proliferation and P450c21 activity.
Journal: The Journal of endocrinology 20020901
Title: The absolute bioavailability of clodronate from two different oral doses.
Journal: Bone 20020901
Title: Bisphosphonates and tumor burden.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801
Title: Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801
Title: Bisphosphonates in the treatment of thalassemia-induced osteoporosis.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20020801
Title: Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits.
Journal: Circulation 20020730
Title: The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors.
Journal: Bioorganic & medicinal chemistry 20020701
Title: Skeletal deposition of clodronate is related to parathyroid function and bone turnover in dialysis patients.
Journal: Clinical nephrology 20020701
Title: Bisphosphonate prodrugs.
Journal: Current medicinal chemistry 20020601
Title: Bisphosphonates influence the proliferation and the maturation of normal human osteoblasts.
Journal: Journal of endocrinological investigation 20020601
Title: Correction of the nonlinear dose response improves the viability of adenoviral vectors for gene therapy of Fabry disease.
Journal: Human gene therapy 20020520
Title: Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.
Journal: Molecular pharmacology 20020501
Title: Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxin.
Journal: American journal of respiratory cell and molecular biology 20020501
Title: Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
Journal: Cancer research 20020501
Title: Effects of topical administration of clodronate on alveolar bone resorption in rats with experimental periodontitis.
Journal: Journal of periodontology 20020501
Title: Complete healing of severe osteoradionecrosis with treatment combining pentoxifylline, tocopherol and clodronate.
Journal: The British journal of radiology 20020501
Title: Is there a dose response relationship for clodronate in the treatment of tumour induced hypercalcaemia?
Journal: British journal of cancer 20020422
Title: [Macrophage depletion inhibits leukocyte recruitment in experimental melanin-induced uveitis (EMIU)].
Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20020401
Title: [Is pamidronate or clodronate better?].
Journal: Vnitrni lekarstvi 20020401
Title: [Bisphosphonate therapy in Paget disease?].
Journal: Deutsche medizinische Wochenschrift (1946) 20020322
Title: Reductions in bone mass, structure, and strength in axial and appendicular skeletons associated with increased turnover after ovariectomy in mature cynomolgus monkeys and preventive effects of clodronate.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020301
Title: Disodium chlodronate prevents bone resorption in experimental periodontitis in rats.
Journal: Journal of periodontology 20020301
Title: Suppression of immunoreactive macrophages in atheromatous lesions of rabbits by clodronate.
Journal: Pharmacology & toxicology 20020301
Title: Involvement of macrophages in the pathogenesis of transmissible spongiform encephalopathies.
Journal: Developmental immunology 20020301
Title: Rapid recovery of platelet count following administration of liposome-encapsulated clodronate in a mouse model of immune thrombocytopenia.
Journal: British journal of haematology 20020201
Title: Electrospray ionization mass spectrometry and tandem mass spectrometry of clodronate and related bisphosphonate and phosphonate compounds.
Journal: Journal of mass spectrometry : JMS 20020201
Title: Clodronate in myelofibrosis: a case report.
Journal: The American journal of the medical sciences 20020201
Title: Bisphosphonate space measurement and dosage requirement for intravenous clodronate treatment of Paget's disease.
Journal: Calcified tissue international 20020201
Title: The role of perivascular and meningeal macrophages in experimental allergic encephalomyelitis.
Journal: Journal of neuroimmunology 20020101
Title: Does postmenopausal hormone replacement therapy affect cardiac autonomic regulation in osteoporotic women?
Journal: Menopause (New York, N.Y.) 20020101
Title: Treatment of complex regional pain syndrome type I.
Journal: European journal of pain (London, England) 20020101
Title: Reduction of instability-induced bone resorption using bisphosphonates: high doses are needed in rats.
Journal: Acta orthopaedica Scandinavica 20020101
Title: Bisphosphonates for the relief of pain secondary to bone metastases.
Journal: The Cochrane database of systematic reviews 20020101
Title: Liposomes--an invaluable tool in bisphosphonate research.
Journal: Cellular & molecular biology letters 20020101
Title: Clodronate treatment reduces serum levels of interleukin-6 soluble receptor in Paget's disease of bone.
Journal: Clinical and experimental rheumatology 20020101
Title: Microstructural properties of bone in rat vertebra after long-term clodronate treatment.
Journal: Journal of bone and mineral metabolism 20020101
Title: Changes in size of periarthritis calcifications in patients with painful shoulder treated with injectable disodium-clodronate.
Journal: International journal of clinical pharmacology research 20020101
Title: Bisphosphonate therapy in multiple myeloma: past, present, future.
Journal: European journal of haematology 20020101
Title: Macrophage-dependent regulation of neutrophil mobilization and chemotaxis during development of sterile peritonitis in the rat.
Journal: European journal of haematology 20020101
Title: [The role of adjuvant clodronate therapy for prevention of bone metastasis in breast cancer].
Journal: Magyar onkologia 20020101
Title: Effects of Cl2MDP-encapsulating liposomes in a murine model of Pseudomonas aeruginosa-induced sepsis.
Journal: Journal of liposome research 20020101
Title: Clodronate liposomes: perspectives in research and therapeutics.
Journal: Journal of liposome research 20020101
Title: Long-term impact of chemotherapy-induced ovarian failure on bone mineral density (BMD) in premenopausal breast cancer patients. The effect of adjuvant clodronate treatment.
Journal: European journal of cancer (Oxford, England : 1990) 20011201
Title: [Parenteral disodium-clodronate in patients with rheumatoid arthritis. A two-month open clinical study].
Journal: Minerva medica 20011201
Title: Effects of long-term administration of clodronate on growing rat bone.
Journal: Calcified tissue international 20011201
Title: Clinical and biochemical response to single infusion of clodronate in active rheumatoid arthritis--a double blind placebo controlled study.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011201
Title: Suppression of T cells results in long-term survival of mouse heart xenografts in C6-deficient rats.
Journal: Xenotransplantation 20011101
Title: The cellular uptake and metabolism of clodronate in RAW 264 macrophages.
Journal: Pharmaceutical research 20011101
Title: Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011015
Title: Critical role of Kupffer cell-derived IL-10 for host defense in septic peritonitis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011001
Title: Comparison of the effects of intravenous pamidronate and oral clodronate on symptoms and bone resorption in patients with metastatic bone disease.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20011001
Title: Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination.
Journal: Glia 20010901
Title: Suppression of chronic streptococcal cell wall-induced arthritis in Lewis rats by liposomal clodronate.
Journal: Rheumatology (Oxford, England) 20010901
Title: The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis.
Journal: Arthritis and rheumatism 20010901
Title: Long-term release of clodronate from biodegradable microspheres.
Journal: AAPS PharmSciTech 20010901
Title: Effects of low-dose, noncytotoxic, intraarticular liposomal clodronate on development of erosions and proteoglycan loss in established antigen-induced arthritis in rabbits.
Journal: Arthritis and rheumatism 20010801
Title: Disodium clodronate in the treatment of diffuse sclerosing osteomyelitis (DSO) of the mandible.
Journal: International journal of oral and maxillofacial surgery 20010801
Title: A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.
Journal: Journal of periodontology 20010801
Title: [Use of clodronic acid in mineral metabolism conditions: state of the art in 2000].
Journal: Minerva medica 20010801
Title: Bisphosphonates in the prevention of bone metastases: current evidence.
Journal: Seminars in oncology 20010801
Title: Adjuvant bisphosphonate therapy: the future.
Journal: Seminars in oncology 20010801
Title: [Bisphosphonates in the treatment of breast carcinoma].
Journal: Polskie Archiwum Medycyny Wewnetrznej 20010801
Title: Bisphosphonates may be useful in treatment of bone metastases.
Journal: Journal of the National Cancer Institute 20010718
Title: Macrophage depletion prevents leukocyte adhesion and disease induction in experimental melanin-protein induced uveitis.
Journal: Experimental eye research 20010701
Title: [Double-blinded controlled study comparing clodronate versus placebo in patients with breast cancer bone metastases].
Journal: Bulletin du cancer 20010701
Title: Kupffer cells and neutrophils as paracrine regulators of the heme oxygenase-1 gene in hepatocytes after hemorrhagic shock.
Journal: Shock (Augusta, Ga.) 20010601
Title: The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro.
Journal: Anti-cancer drugs 20010601
Title: A method for the selective depletion of perivascular and meningeal macrophages in the central nervous system.
Journal: Journal of neuroimmunology 20010601
Title: Long-term follow-up of a prospective, double-blind, placebo-controlled randomized trial of clodronate in multiple myeloma.
Journal: British journal of haematology 20010601
Title: Induction of proliferation and augmented cytotoxicity of gammadelta T lymphocytes by bisphosphonate clodronate.
Journal: Blood 20010501
Title: Atypical familial Paget's disease of bone.
Journal: Joint, bone, spine : revue du rhumatisme 20010501
Title: CD8+ phagocytes in focal ischemia of the rat brain: predominant origin from hematogenous macrophages and targeting to areas of pannecrosis.
Journal: Acta neuropathologica 20010501
Title: Expression of Th2 cytokines decreases the development of and improves Behçet's disease-like symptoms induced by herpes simplex virus in mice.
Journal: The Journal of infectious diseases 20010415
Title: Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010401
Title: Analgesic effect of bisphosphonates in mice.
Journal: Pain 20010401
Title: Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line.
Journal: British journal of cancer 20010401
Title: The effect of clodronate and antioestrogens on bone loss associated with oestrogen withdrawal in postmenopausal women with breast cancer.
Journal: British journal of cancer 20010401
Title: Changes in murine bone marrow macrophages and erythroid burst-forming cells following the intravenous injection of liposome-encapsulated dichloromethylene diphosphonate (Cl2MDP).
Journal: European journal of haematology 20010401
Title: Bone marrow transplant conditioning intensified with liposomal clodronate to eliminate residual host antigen presenting cells fails to ameliorate GVHD and increases PERI-BMT mortality.
Journal: Transplantation 20010315
Title: Incidence and severity of herpetic stromal keratitis: impaired by the depletion of lymph node macrophages.
Journal: Experimental eye research 20010301
Title: A mouse model for postoperative fatal enteritis due to Staphylococcus infection.
Journal: The Journal of surgical research 20010301
Title: Effects of clodronate on vertebral fracture risk in osteoporosis: a 1-year interim analysis.
Journal: Bone 20010301
Title: An immunomodulatory procedure that stabilizes transgene expression and permits readministration of E1-deleted adenovirus vectors.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20010301
Title: Use of bisphosphonates for the treatment of metastatic bone pain. A survey of palliative physicians in the UK.
Journal: Palliative medicine 20010301
Title: Depletion of systemic macrophages by liposome-encapsulated clodronate attenuates striatal macrophage invasion and neurodegeneration following local endotoxin infusion in gerbils.
Journal: Brain research 20010216
Title: Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010201
Title: Effects of calcium and lipophilicity on transport of clodronate and its esters through Caco-2 cells.
Journal: International journal of pharmaceutics 20010201
Title: A combination of subtherapeutic doses of chemically modified doxycycline (CMT-8) and a bisphosphonate (clodronate) inhibits bone loss in the ovariectomized rat: a dynamic histomorphometric and gene expression study.
Journal: Current medicinal chemistry 20010201
Title: Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation.
Journal: Osteoarthritis and cartilage 20010201
Title: Treatment of osteoporosis with bisphosphonates.
Journal: Rheumatic diseases clinics of North America 20010201
Title: The use of bisphosphonate for the palliative treatment of painful bone metastasis due to hormone refractory prostate cancer.
Journal: The Journal of urology 20010101
Title: Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010101
Title: Bone mineral density in multiple myeloma patients after intravenous clodronate therapy.
Journal: Acta medica Austriaca 20010101
Title: One-month follow-up of patients treated by intravenous clodronate for acute pain induced by osteoporotic vertebral fracture.
Journal: Drugs under experimental and clinical research 20010101
Title: Effect of intramuscular clodronate on bone mass and metabolism in osteoporotic women.
Journal: International journal of tissue reactions 20010101
Title: Reduction of visible bone metastases by clodronate therapy in breast cancer.
Journal: European journal of gynaecological oncology 20010101
Title: Strategies for management of prostate cancer-related bone pain.
Journal: Drugs & aging 20010101
Title: [Use of clodronate in the adjuvant treatment of breast cancer is questionable for the time being].
Journal: Duodecim; laaketieteellinen aikakauskirja 20010101
Title: Bisphosphonates induce breast cancer cell death in vitro.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20001101
Title: Bisphosphonates induce apoptosis in human breast cancer cell lines.
Journal: British journal of cancer 20000401
Title: Endotoxin-induced aggravation of preservation-reperfusion injury of rat liver and its modulation.
Journal: Journal of hepatology 20000101
Title: Calcitriol-mediated hypercalcaemia and increased interleukins in a patient with sarcoid myopathy.
Journal: Clinical rheumatology 19990101
Title: Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19980401
Title: An in vitro and in vivo study of cytokines in the acute-phase response associated with bisphosphonates.
Journal: Calcified tissue international 19971101
Title: Cauda equina syndrome with pagetic vertebral fusion. Clinical recovery under calcium-vitamin D supplementation plus clodronate after apparent failure of pamidronate and acquired resistance to etidronate.
Journal: Revue du rhumatisme (English ed.) 19970101
Title: Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages.
Journal: Molecular pharmacology 19961101
Title: Clodronate therapy of metastatic bone disease in patients with prostatic carcinoma.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 19890101
Title: Mönkkönen J, et al. Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by RAW 264 cells. Life Sci. 1994;54(14):PL229‐PL234.
Title: Tanakol R, et al. Clodronic acid in the treatment of postmenopausal osteoporosis. Clin Drug Investig. 2007;27(6):419‐433.
Title: Itoh F, et al. Effects of clodronate and alendronate on local and systemic changes in bone metabolism in rats with adjuvant arthritis. Inflammation. 2004;28(1):15‐21.
