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22662-39-1,MFCD00682899
Catalog No.:AA00ILNZ

22662-39-1 | Rafoxanide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99%
in stock  
$7.00   $5.00
- +
1g
99%
in stock  
$21.00   $15.00
- +
5g
99%
in stock  
$27.00   $19.00
- +
25g
99%
in stock  
$52.00   $36.00
- +
100g
99%
in stock  
$171.00   $120.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ILNZ
Chemical Name:
Rafoxanide
CAS Number:
22662-39-1
Molecular Formula:
C19H11Cl2I2NO3
Molecular Weight:
626.0105
MDL Number:
MFCD00682899
SMILES:
Clc1ccc(cc1)Oc1ccc(cc1Cl)NC(=O)c1cc(I)cc(c1O)I
NSC Number:
355278
Properties
Computed Properties
 
Complexity:
507  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
7  

Literature

Title: Introgression of ivermectin resistance genes into a susceptible Haemonchus contortus strain by multiple backcrossing.

Journal: PLoS pathogens 20120201

Title: An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.

Journal: Toxicology letters 20120105

Title: Anthelmintic drug residues in beef: UPLC-MS/MS method validation, European retail beef survey, and associated exposure and risk assessments.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.

Journal: PloS one 20120101

Title: Determination of closantel and rafoxanide in animal tissues by online anionic mixed-mode solid-phase extraction followed by isotope dilution liquid chromatography tandem mass spectrometry.

Journal: Journal of separation science 20110601

Title: Potential drug development candidates for human soil-transmitted helminthiases.

Journal: PLoS neglected tropical diseases 20110601

Title: Stability during cooking of anthelmintic veterinary drug residues in beef.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110201

Title: Effect of three anthelmentics on disposition kinetics of florfenicol in goats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101201

Title: Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells.

Journal: Chemico-biological interactions 20100805

Title: Biochemical analysis of a recombinant glutathione transferase from the cestode Echinococcus granulosus.

Journal: Acta tropica 20100401

Title: Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS.

Journal: Journal of separation science 20100201

Title: Quantitative analysis of closantel and rafoxanide in bovine and ovine muscles by high-performance liquid chromatography with fluorescence detection.

Journal: Journal of AOAC International 20100101

Title: Multi-residue determination of phenolic and salicylanilide anthelmintics and related compounds in bovine kidney by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.

Journal: PLoS neglected tropical diseases 20090701

Title: The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles.

Journal: Veterinary parasitology 20090610

Title: Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel.

Journal: PLoS pathogens 20090401

Title: Comparative pharmacokinetics of ivermectin alone and a novel formulation of ivermectin and rafoxanide in calves and sheep.

Journal: Parasitology research 20080501

Title: Comparative efficacy of different anthelmintics against fenbendazole-resistant nematodes of pashmina goats.

Journal: Veterinary research communications 20070801

Title: A dual anthelmintic treatment strategic scheme for the control of fasciolosis in dairy sheep farms.

Journal: Parasitology research 20061101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Field trial on comparative efficacy of four fasciolicides against natural liver fluke infection in cattle.

Journal: Veterinary parasitology 20060218

Title: The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.

Journal: The Journal of parasitology 20040801

Title: Anthelmintic resistance of nematodes in communally grazed goats in a semi-arid area of South Africa.

Journal: Journal of the South African Veterinary Association 20030901

Title: Anthelmintic resistance on an organized sheep farm in India.

Journal: Tropical animal health and production 20010701

Title: Backbone rearrangements of steroidal 5-enes.

Journal: Journal of the Chemical Society. Perkin transactions 1 19750101

Title: van Wyk JA, et al. Two field strains of Haemonchus contortus resistant to rafoxanide. Onderstepoort J Vet Res. 1987 Jun;54(2):143-6.

Title: Prichard RK, et al. The metabolic profile of adult Fasciola hepatica obtained from rafoxanide-treated sheep. Parasitology. 1978 Jun;76(3):277-88.

Title: Cornish RA, et al. The in vivo effects of rafoxanide on the energy metabolism of Fasciola hepatica. Int J Parasitol. 1977 Jun;7(3):217-20.

Title: Rafoxanide

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