Catalog No.:AA003989

226929-39-1 | 4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine

Name: Name:4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine
Brand: AABLOCKS
SKU: AA003989
Availability: InStock
Rating: 90 (10 reviews)

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1mg

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$63.00 $44.00

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5mg

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$169.00 $118.00

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10mg

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$276.00 $193.00

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA003989

Chemical Name:

4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine

CAS Number:

226929-39-1

Molecular Formula:

C30H27BrN4O2

Molecular Weight:

555.4650

MDL Number:

MFCD20926350

SMILES:

Brc1ccc(cc1)Cn1cncc1Cn1cc(c(c1)c1cccc2c1cccc2)C(=O)N1CCOCC1

Properties

Computed Properties

Complexity:

756

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

4.6

Literature

Title: The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signal pathways.

Journal: Molecular pharmacology 20100701

Title: The farnesyltransferase inhibitor, LB42708, inhibits growth and induces apoptosis irreversibly in H-ras and K-ras-transformed rat intestinal epithelial cells.

Journal: Toxicology and applied pharmacology 20060915

Title: Targeting RAS signalling pathways in cancer therapy.

Journal: Nature reviews. Cancer 20030101

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