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2270-40-8,MFCD00866334
Catalog No.:AA00BC64

2270-40-8 | DIACETOXYSCIRPENOL

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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BC64
Chemical Name:
DIACETOXYSCIRPENOL
CAS Number:
2270-40-8
Molecular Formula:
C19H26O7
Molecular Weight:
366.4055
MDL Number:
MFCD00866334
SMILES:
CC(=O)OC[C@]12CCC(=C[C@H]1O[C@H]1[C@@]3([C@]2(C)[C@H](OC(=O)C)[C@H]1O)CO3)C
NSC Number:
177378
Properties
Computed Properties
 
Complexity:
687  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
0.2  

Literature

Title: Role of Peptide YY3-36 and Glucose-Dependent Insulinotropic Polypeptide in Anorexia Induction by Trichothecences T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170901

Title: Trichothecenes and mycoflora in wheat harvested in nine locations in Buenos Aires province, Argentina.

Journal: Mycopathologia 20080201

Title: Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells.

Journal: Toxicology and applied pharmacology 20070715

Title: Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana.

Journal: Journal of experimental botany 20070101

Title: Differential induction of apoptosis by type A and B trichothecenes in Jurkat T-lymphocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060901

Title: Inhibition of sodium glucose cotransporter-I expressed in Xenopus laevis oocytes by 4-acetoxyscirpendiol from Cordyceps takaomantana (anamorph = Paecilomyces tenuipes).

Journal: Medical mycology 20060201

Title: Two lepidopteran cell lines stably transformed by the abc transporter gene pdr5 show tolerance to diacetoxyscirpenol.

Journal: In vitro cellular & developmental biology. Animal 20060101

Title: Development of a multicomponent method for Fusarium toxins using LC-MS/MS and its application during a survey for the content of T-2 toxin and deoxynivalenol in various feed and food samples.

Journal: Food additives and contaminants 20050801

Title: 4-acetoxyscirpendiol of Paecilomyces tenuipes inhibits Na(+)/D-glucose cotransporter expressed in Xenopus laevis oocytes.

Journal: Journal of biochemistry and molecular biology 20050331

Title: A rapid multiresidual determination of type A and type B trichothecenes in wheat flour by HPLC-ESI-MS.

Journal: Food additives and contaminants 20050301

Title: A pathological condition possibly caused by spontaneous trichotecene poisoning in Brahma poultry: first report.

Journal: Avian pathology : journal of the W.V.P.A 20040601

Title: The effect of chronic feeding of diacetoxyscirpenol and T-2 toxin on performance, health, small intestinal physiology and antibody production in turkey poults.

Journal: British poultry science 20030301

Title: Effects of the tricothecene mycotoxin diacetoxyscirpenol on egg production of broiler breeders.

Journal: Poultry science 20021201

Title: Evaluation of the efficacy of a feed additive to ameliorate the toxic effects of 4,15-diacetoxiscirpenol in growing chicks.

Journal: Poultry science 20021001

Title: Natural contamination of oat with group A trichothecene mycotoxins in Poland.

Journal: Food additives and contaminants 20020501

Title: Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK).

Journal: Human & experimental toxicology 20010201

Title: Chromatographic methods for trichothecenes.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: Screening for new compounds with antiherpes activity.

Journal: Antiviral research 19841001

Title: Lautraite S, et al. In vitro effects of diacetoxyscirpenol (DAS) on human and rat granulo-monocytic progenitors. Mycopathologia. 1997;140(1):59-64.

Title: Hoerr FJ, et al.Mycotoxicosis caused by a single dose of T-2 toxin or diacetoxyscirpenol in broiler chickens. Vet Pathol. 1981 Sep;18(5):652-64.

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