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2276-90-6,MFCD00800738
Catalog No.:AA006WJX

2276-90-6 | Iotalamic acid

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Purity
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5mg
99%
1 week  
$1,257.00   $880.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006WJX
Chemical Name:
Iotalamic acid
CAS Number:
2276-90-6
Molecular Formula:
C11H9I3N2O4
Molecular Weight:
613.9136
MDL Number:
MFCD00800738
SMILES:
CNC(=O)c1c(I)c(NC(=O)C)c(c(c1I)C(=O)O)I
NSC Number:
759891
Properties
Properties
 
Form:
Solid  
MP:
>219°C (dec.)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
421  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
1.9  

Downstream Synthesis Route
Literature

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Title: Colon distension, perceived burden and side-effects of CT-colonography for screening using hyoscine butylbromide or glucagon hydrochloride as bowel relaxant.

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Title: Net endogenous acid production is associated with a faster decline in GFR in African Americans.

Journal: Kidney international 20120701

Title: Feasibility of using automated insufflated carbon dioxide (CO2) for luminal distension in 3.0T MR colonography.

Journal: European journal of radiology 20120601

Title: Superior labral anterior-to-posterior lesions: comparison of external rotation and active supination CT arthrography with neutral CT arthrography.

Journal: Radiology 20120401

Title: Inclusion of computed tomographic colonography on pre-operative CT for patients with colorectal cancer.

Journal: European journal of radiology 20120301

Title: Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease.

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Title: Visualisation of the temporary cavity by computed tomography using contrast material.

Journal: International journal of legal medicine 20120101

Title: Impact of short-duration administration of N-acetylcysteine, probucol and ascorbic acid on contrast-induced cytotoxicity.

Journal: Journal of nephrology 20120101

Title: Dynamic computed tomography of angioedema of the small bowel induced by iodinated contrast medium: prompted by coughing-related motion artifact.

Journal: Clinical imaging 20120101

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Short-term vitamin D receptor activation increases serum creatinine due to increased production with no effect on the glomerular filtration rate.

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Title: Radiologists' performance in the diagnosis of acute intestinal ischemia, using MDCT and specific CT findings, using a variety of CT protocols.

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Title: Accuracy of intra-articular injection of the glenohumeral joint: a modified anterior approach.

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Title: Use of angioscanning in the surgical planning of perforator flaps in the lower extremities.

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Title: Formation of toxic iodinated disinfection by-products from compounds used in medical imaging.

Journal: Environmental science & technology 20110815

Title: Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease.

Journal: Kidney international 20110801

Title: Relative performance of the MDRD and CKD-EPI equations for estimating glomerular filtration rate among patients with varied clinical presentations.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110801

Title: Hydrophilic pyrazine dyes as exogenous fluorescent tracer agents for real-time point-of-care measurement of glomerular filtration rate.

Journal: Journal of medicinal chemistry 20110728

Title: Use of laxative-augmented contrast medium in the evaluation of colorectal foci at FDG PET.

Journal: Radiology 20110501

Title: [Measurement of renal function in clinical practice: principles and limitations].

Journal: Journal de radiologie 20110401

Title: Potentially modifiable factors affecting the progression of autosomal dominant polycystic kidney disease.

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Title: Copeptin, a surrogate marker of vasopressin, is associated with disease severity in autosomal dominant polycystic kidney disease.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110201

Title: Reducing the oral contrast dose in CT colonography: evaluation of faecal tagging quality and patient acceptance.

Journal: Clinical radiology 20110101

Title: Debate: CON Position. Formal assessment of donor kidney function should be mandatory.

Journal: American journal of nephrology 20110101

Title: Editorial perspective. Donor kidney function - are we focusing on the trees or the forest?

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Title: Cystatin C: a possible sensitive marker for detecting potential kidney injury after computed tomography coronary angiography.

Journal: Journal of computer assisted tomography 20110101

Title: Modified radiology-guided percutaneous gastrostomy (MRPG) for patients with complete obstruction of the upper digestive tract and who are without endoscopic or nasogastric access.

Journal: Korean journal of radiology 20110101

Title: Re: Tips and tricks of percutaneous gastrostomy under image guidance in patients with limited access.

Journal: Korean journal of radiology 20110101

Title: Comparison of combined oral and i.v. contrast-enhanced versus single i.v. contrast-enhanced mdct for the detection of acute appendicitis.

Journal: JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR) 20110101

Title: CT colonography with limited bowel preparation for the detection of colorectal neoplasia in an FOBT positive screening population.

Journal: Abdominal imaging 20101201

Title: Measurement of glomerular filtration rate in anesthetized and conscious rhesus monkeys (Macaca mulatta).

Journal: American journal of veterinary research 20101201

Title: Renal function equations before and after living kidney donation: a within-individual comparison of performance at different levels of renal function.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20101101

Title: Validation of the revised Schwartz estimating equation in a predominantly non-CKD population.

Journal: Pediatric nephrology (Berlin, Germany) 20101101

Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.

Journal: International journal of environmental research and public health 20101101

Title: Estimating glomerular filtration rate in children at serial follow-up when height is unknown.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20101001

Title: Estimation of glomerular filtration rate by using serum cystatin C and serum creatinine concentrations in patients with human immunodeficiency virus.

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Title: Accurate, fast, and convenient measurement of glomerular filtration rate in potential renal transplant donors.

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Title: [Perioperative cholangiography: a case study at Yaounde (Cameroon)].

Journal: Medecine tropicale : revue du Corps de sante colonial 20100801

Title: Gastric emptying time of oral contrast material in children and adolescents undergoing abdominal computed tomography.

Journal: Journal of pediatric gastroenterology and nutrition 20100701

Title: Imprecision of urinary iothalamate clearance as a gold-standard measure of GFR decreases the diagnostic accuracy of kidney function estimating equations.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100701

Title: Low-fiber diet in limited bowel preparation for CT colonography: Influence on image quality and patient acceptance.

Journal: AJR. American journal of roentgenology 20100701

Title: Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20100601

Title: The CKD-EPI equation for estimating GFR from serum creatinine: real improvement or more of the same?

Journal: Clinical journal of the American Society of Nephrology : CJASN 20100601

Title: Iothalamate quantification by tandem mass spectrometry to measure glomerular filtration rate.

Journal: Clinical chemistry 20100401

Title: Flow tracing microparticle sensors designed for enhanced X-ray contrast.

Journal: Biosensors & bioelectronics 20100315

Title: Ioxitalamate induces renal tubular apoptosis via activation of renal efferent nerve-mediated adrenergic signaling, renin activity, and reactive oxygen species production in rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100301

Title: Imprecision of creatinine-based GFR estimates in uninephric kidney donors.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20100301

Title: CT colonography with minimal bowel preparation: evaluation of tagging quality, patient acceptance and diagnostic accuracy in two iodine-based preparation schemes.

Journal: European radiology 20100201

Title: Accuracy of multidetector computed tomography in differentiating primary epiploic appendagitis from left acute colonic diverticulitis associated with secondary epiploic appendagitis.

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Title: Severe transient leukopenia following hysterosalpingography.

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Title: [Assessment of the new CKD-EPI equation to estimate the glomerular filtration rate].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101

Title: Quantitation of iothalamate in urine and plasma using liquid chromatography electrospray tandem mass spectrometry (HPLC-ESI-MS/MS).

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Micro-computed tomography-based phenotypic approaches in embryology: procedural artifacts on assessments of embryonic craniofacial growth and development.

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Title: N-acetylcysteine attenuates iodine contrast agent-induced nephropathy in 5/6-nephrectomized rats.

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Title: Posteroinferior labral cleft at direct CT arthrography of the shoulder by using multidetector CT: is this a normal variant?

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Title: Carcinoid tumors of the pancreas: dynamic CT and MRI features with pathological correlation.

Journal: Abdominal imaging 20091101

Title: Renal function in glycogen storage disease type I, natural course, and renopreservative effects of ACE inhibition.

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Title: MDCT for suspected acute appendicitis in adults: impact of oral and IV contrast media at standard-dose and simulated low-dose techniques.

Journal: AJR. American journal of roentgenology 20091101

Title: Glomerular filtration rate measurements by 125I-iothalamate should be corrected for inaccurate urine collections with 131I-hippuran.

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Title: Spectrum of focal benign musculoskeletal 18F-FDG uptake at PET/CT of the shoulder and pelvis.

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Title: Characterization of a novel model for investigation of radiocontrast nephrotoxicity.

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Title: Bilateral displaced femoral neck fractures after myoclonic seizure treated with bilateral total hip arthroplasties.

Journal: American journal of orthopedics (Belle Mead, N.J.) 20090201

Title: Differential effects of N-acetylcysteine, theophylline or bicarbonate on contrast-induced rat renal vasoconstriction.

Journal: American journal of nephrology 20090101

Title: GFR estimates using cystatin C are superior to serum creatinine in adult patients with cystic fibrosis.

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Title: Assessment of iothalamate plasma clearance: duration of study affects quality of GFR.

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Title: Rapid analysis of iodinated X-ray contrast media in secondary and tertiary treated wastewater by direct injection liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20081212

Title: Is the new Mayo Clinic Quadratic equation useful for the estimation of glomerular filtration rate in type 2 diabetic patients?

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Journal: Gastrointestinal endoscopy 20081201

Title: Functional immunoassay technology (FIT), a new approach for measuring physiological functions: application of FIT to measure glomerular filtration rate (GFR).

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Title: Influence of tagged fecal material on detectability of colorectal polyps at CT: phantom study.

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Title: Comparison of neutral oral contrast versus positive oral contrast medium in abdominal multidetector CT.

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Title: Feasibility and impact of the measurement of extracellular fluid volume simultaneous with GFR by 125I-iothalamate.

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Title: A comparison of change in measured and estimated glomerular filtration rate in patients with nondiabetic kidney disease.

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Title: Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.

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Title: Iodinated contrast induced renal vasoconstriction is due in part to the downregulation of renal cortical and medullary nitric oxide synthesis.

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Title: Renal extraction of cystatin C vs 125I-iothalamate in hypertensive patients.

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Title: Prospective comparison of helical CT of the abdomen and pelvis without and with oral contrast in assessing acute abdominal pain in adult Emergency Department patients.

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Title: Assessing glomerular filtration rate by estimation equations in kidney transplant recipients.

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Title: Simple HPLC-UV method for determination of iohexol, iothalamate, p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105

Title: PET/CT with intravenous contrast can be used for PET attenuation correction in cancer patients.

Journal: European journal of nuclear medicine and molecular imaging 20051001

Title: Virtopsy: postmortem minimally invasive angiography using cross section techniques--implementation and preliminary results.

Journal: Journal of forensic sciences 20050901

Title: Analysis of iodinated X-ray contrast agents in water samples by ion chromatography and inductively-coupled plasma mass spectrometry.

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Title: Performance of the Cockcroft-Gault and modification of diet in renal disease equations in estimating GFR in ill hospitalized patients.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20050801

Title: Cytotoxic effects of ionic high-osmolar, nonionic monomeric, and nonionic iso-osmolar dimeric iodinated contrast media on renal tubular cells in vitro.

Journal: Radiology 20050601

Title: CT voiding cystourethrography using 16-MDCT for the evaluation of female urethral diverticula: initial experience.

Journal: AJR. American journal of roentgenology 20050501

Title: Telebrix Gastro in the management of adhesive small bowel obstruction.

Journal: Gastroenterologie clinique et biologique 20050501

Title: An alternative formula to the Cockcroft-Gault and the modification of diet in renal diseases formulas in predicting GFR in individuals with type 1 diabetes.

Journal: Journal of the American Society of Nephrology : JASN 20050401

Title: Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia.

Journal: Kidney international 20050201

Title: Simultaneous determination of anions in nanoliter volumes.

Journal: Kidney international 20050101

Title: Power injection of microcatheters: an in vitro comparison.

Journal: Journal of vascular and interventional radiology : JVIR 20050101

Title: Sensitivity variation of doped Fricke gel irradiated with monochromatic synchrotron X rays between 33.5 and 80 keV.

Journal: Radiation protection dosimetry 20050101

Title: The value of contrast-enhanced helical CT scan with rectal contrast enema in the diagnosis of acute appendicitis.

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Title: [Methods for the quantification of left ventricular volumes assessed by radionuclide ventriculography (first part)].

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Title: Nephropathy in critically Ill patients without preexisting renal disease.

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Title: Summaries for patients. Estimating kidney function in healthy people.

Journal: Annals of internal medicine 20041221

Title: Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease.

Journal: Annals of internal medicine 20041221

Title: CT features of the accessory spleen.

Journal: AJR. American journal of roentgenology 20041201

Title: A comparison of iothalamate-GFR and serum creatinine-based outcomes: acceleration in the rate of GFR decline in the African American Study of Kidney Disease and Hypertension.

Journal: Journal of the American Society of Nephrology : JASN 20041201

Title: Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:Ig fusion protein.

Journal: Clinical immunology (Orlando, Fla.) 20041101

Title: Effect of contrast media on vascular smooth muscle cells.

Journal: Acta radiologica (Stockholm, Sweden : 1987) 20041001

Title: Non-invasive imaging of coronary artery with 16-slice spiral computed tomography.

Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20040901

Title: Renal interaction between itraconazole and cimetidine.

Journal: Journal of clinical pharmacology 20040801

Title: Hypersensitivity to intravenous contrast material causing CT appearance of bowel wall thickening.

Journal: Clinical radiology 20040701

Title: CT and MR imaging of nitinol stents with radiopaque distal markers.

Journal: Journal of vascular and interventional radiology : JVIR 20040601

Title: Interferences in clinical capillary zone electrophoresis of serum proteins.

Journal: Electrophoresis 20040601

Title: Studies on experimental iodine allergy: 2. Iodinated protein antigens and their generation from inorganic and organic iodine-containing chemicals.

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Title: Decline in native renal function early after bladder-drained pancreas transplantation alone.

Journal: Transplantation 20040327

Title: Evaluation of the nitric oxide production in rat renal artery smooth muscle cells culture exposed to radiocontrast agents.

Journal: Kidney international 20040201

Title: Salutary effects of radiopaque contrast media on the survival of random-pattern skin flaps in the rat: an experimental study.

Journal: Microsurgery 20040101

Title: Prediction of GFR in liver transplant candidates.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20031201

Title: Simultaneous voiding cystourethrography and voiding urosonography reveals utility of sonographic diagnosis of vesicoureteral reflux in children.

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Title: Contrast-enhanced US of microcirculation of superficially implanted tumors in rats.

Journal: Radiology 20031101

Title: A comparison of prediction equations for estimating glomerular filtration rate in adults without kidney disease.

Journal: Journal of the American Society of Nephrology : JASN 20031001

Title: Peak contrast enhancement in CT and MR angiography: when does it occur and why? Pharmacokinetic study in a porcine model.

Journal: Radiology 20030601

Title: Glomerular filtration rate in children with solid tumors: normative values and a new method for estimation.

Journal: Pediatric hematology and oncology 20030601

Title: Ambulatory GFR measurement with cold iothalamate in adults with chronic kidney disease.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030401

Title: Liquid chromatography for iothalamate in biological samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

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Journal: Revue medicale de Liege 20030201

Title: Dynamic computed tomography of the pituitary gland in dogs with pituitary-dependent hyperadrenocorticism.

Journal: Journal of veterinary internal medicine 20030101

Title: Inadvertent intrathecal use of ionic contrast agent.

Journal: European radiology 20021201

Title: Iothalamate measured by capillary electrophoresis is a suitable alternative to radiolabeled inulin in renal micropuncture.

Journal: Kidney international 20020901

Title: Functional effects of renal artery stent placement on treated and contralateral kidneys.

Journal: Kidney international 20020801

Title: Diuretic Doppler ultrasonography in chronic unilateral partial ureteric obstruction in dogs.

Journal: BJU international 20020701

Title: Evaluation of renal function in transplant patients on tacrolimus therapy.

Journal: Journal of clinical pharmacology 20020701

Title: Effects of intrathecal injection of diatrizoate on dopamine receptors.

Journal: Academic radiology 20020701

Title: Mechanisms of blood pressure change after bolus injections of X-ray contrast media.

Journal: Academic radiology 20020501

Title: Gadopentetate dimeglumine as an intradiscal contrast agent.

Journal: Spine 20020415

Title: Short-term moderate sodium restriction induces relative hyperfiltration in normotensive normoalbuminuric Type I diabetes mellitus.

Journal: Diabetologia 20020401

Title: Comparative cytotoxicity of low-osmolar nonionic and high-osmolar ionic contrast media to dog gallbladder epithelial cells.

Journal: Gastrointestinal endoscopy 20020301

Title: Plasma exogenous creatinine clearance test in dogs: comparison with other methods and proposed limited sampling strategy.

Journal: Journal of veterinary internal medicine 20020101

Title: [The value and adaptability of glomerular filtration rate and reserve test (review of the literature)].

Journal: Medicina (Kaunas, Lithuania) 20020101

Title: Differential effects of radiocontrast agents on human umbilical vein endothelial cells: cytotoxicity and modulators of thrombogenicity.

Journal: European journal of medical research 20011120

Title: Comparison of unenhanced and contrast-enhanced spiral CT for assessing interval change in patients with colorectal liver metastases.

Journal: Academic radiology 20010801

Title: [Comparison of iodinated and barium-containing contrast media of different viscosity in the detection of pharyngeal perforation].

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Title: Ionic and non-ionic contrast agent-mediated endothelial injury. Quantitative analysis of cell proliferation during endothelial repair.

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Title: Discrimination of small hepatic hemangiomas from hypervascular malignant tumors smaller than 3 cm with three-phase helical CT.

Journal: Radiology 20010601

Title: Changes in intrarenal oxygenation as evaluated by BOLD MRI in a rat kidney model for radiocontrast nephropathy.

Journal: Journal of magnetic resonance imaging : JMRI 20010501

Title: A simple method for the identification and assay of iopamidol and iothalamate meglumine in pharmaceutical samples based on proton nuclear magnetic resonance spectroscopy.

Journal: Die Pharmazie 20010201

Title: Excretory urography by intraosseous injection of contrast media in a rabbit model.

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Title: Renal dysfunction associated with the perioperative use of diclofenac.

Journal: Anesthesia and analgesia 19991001

Title: Are iodinated contrast agents detrimental in acute cerebral ischemia? An experimental study in rats.

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Title: Failure of insulin-like growth factor 1 to improve radiocontrast nephropathy.

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Title: Comparative study: Endografine (diatrizoate), Vasurix polyvidone (acetrizoate), Dimer-X (iocarmate) and Hexabrix (ioxaglate) in hysterosalpingography.

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Title: Hexabrix (ioxaglate), a new low osmolality contrast agent for lumbar epidural double-catheter venography.

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Title: Meglumine diatrizoate v. iothalamate: comparison of seizure-inducing potential.

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Title: Experimental evaluation of sodium-methylglucamine iothalamate (MP-3064): cardiovascular responses following proximal aortic injection.

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Tags:2276-90-6 Molecular Formula|2276-90-6 MDL|2276-90-6 SMILES|2276-90-6 Iotalamic acid