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22910-60-7,MFCD03093717
Catalog No.:AA002LDP

22910-60-7 | Ginkgolic Acid

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1mg
≥95%
in stock  
$89.00   $62.00
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5mg
98% by HPLC
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$156.00   $109.00
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10mg
98% by HPLC
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$219.00   $153.00
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25mg
98% by HPLC
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$392.00   $274.00
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50mg
98% by HPLC
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$622.00   $435.00
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100mg
98% by HPLC
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$1,029.00   $720.00
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500mg
98% by HPLC
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$3,179.00   $2,226.00
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1000mg
98% by HPLC
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$5,049.00   $3,534.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002LDP
Chemical Name:
Ginkgolic Acid
CAS Number:
22910-60-7
Molecular Formula:
C22H34O3
Molecular Weight:
346.5036
MDL Number:
MFCD03093717
SMILES:
CCCCCC/C=C\CCCCCCCc1cccc(c1C(=O)O)O
Properties
Computed Properties
 
Complexity:
364  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
14  
XLogP3:
8.5  

Literature

Title: Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice.

Journal: Toxicology and applied pharmacology 20180415

Title: Metabolic profiling of the hepatotoxicity and nephrotoxicity of Ginkgolic acids in rats using ultra-performance liquid chromatography-high-definition mass spectrometry.

Journal: Chemico-biological interactions 20170801

Title: Non-specific SIRT inhibition as a mechanism for the cytotoxicity of ginkgolic acids and urushiols.

Journal: Toxicology letters 20140902

Title: Small ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor α.

Journal: The FEBS journal 20140701

Title: Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture.

Journal: Parasitology research 20111101

Title: Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.

Journal: Journal of agricultural and food chemistry 20111026

Title: Development of high performance liquid chromatography/electrospray ionization mass spectrometry for assay of ginkgolic acid (15:1) in rat plasma and its application to pharmacokinetics study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis.

Journal: Chemotherapy 20100101

Title: Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange.

Journal: Rapid communications in mass spectrometry : RCM 20090701

Title: Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes.

Journal: Toxicology letters 20090622

Title: [Studies on dynamic change of total ginkgolic acids in Ginkgo biloba leaves of different aged trees and different collecting seasons].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

Title: Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate.

Journal: Chemistry & biology 20090227

Title: [Determination of ginkgolic acids in Ginkgo biloba leaves by gas chromatography with on-line pyrolytic methylation].

Journal: Se pu = Chinese journal of chromatography 20081101

Title: Anti-Toxoplasma gondii activity of GAS in vitro.

Journal: Journal of ethnopharmacology 20080813

Title: Design and evaluation of anacardic acid derivatives as anticavity agents.

Journal: European journal of medicinal chemistry 20080601

Title: [Preparation of five ginkgolic acid monomers and their molluscicidal effects against Oncomelania hupensis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20070801

Title: [Study on anti-bacterium activity of ginkgolic acids and their momomers].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040901

Title: Quantification of allergenic urushiols in extracts of Ginkgo biloba leaves, in simple one-step extracts and refined manufactured material (EGb 761).

Journal: Phytochemical analysis : PCA 20040101

Title: Quantitative analysis of ginkgolic acids from Ginkgo leaves and products using 1H-NMR.

Journal: Phytochemical analysis : PCA 20040101

Title: [Determination of ginkgolic acids in Ginkgo biloba extract and its preparations by high performance liquid chromatography].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20031101

Title: [Isolation and HPLC analysis of ginkgolic acid].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030801

Title: In vitro evaluation of the cytotoxic potential of alkylphenols from Ginkgo biloba L.

Journal: Toxicology 20020815

Title: [Determination of ginkgolic acids by high performance liquid chromatography].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020701

Title: Pharmaceutical quality of different Ginkgo biloba brands.

Journal: The Journal of pharmacy and pharmacology 20020501

Title: Reversed-phase argentation high-performance liquid chromatography in phytochemical analysis of ginkgolic acids in leaves from Ginkgo biloba L.

Journal: Journal of chromatography. A 20020118

Title: Ginkgolic acids induce neuronal death and activate protein phosphatase type-2C.

Journal: European journal of pharmacology 20011026

Title: Preparative isolation and dual column high-performance liquid chromatography of ginkgolic acids from Ginkgo biloba.

Journal: Journal of chromatography. A 20010928

Title: [Separation and quantitative analysis of ginkgolic acids from Ginkgo biloba leaves by reverse phase argentation high performance liquid chromatography].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010801

Title: Determination of ginkgolic acids from Ginkgo biloba leaves by reversed-phase argentation high performance liquid chromatography.

Journal: Se pu = Chinese journal of chromatography 20010501

Title: Evidence for toxic effects of alkylphenols from Ginkgo biloba in the hen's egg test (HET).

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20010301

Title: Dr. Gordon Bates: a personal war against VD.

Journal: Dimensions in health service 19751201

Title: Fukuda I, et al. Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. Chem Biol. 2009 Feb 27;16(2):133-40.

Title: Lü JM, et al. Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro. Med Sci Monit. 2012 Aug;18(8):BR293-298.

Title: Zhou C, et al. Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis. Chemotherapy. 2010;56(5):393-402.

Title: Qiu F, et al. Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice. Toxicol Appl Pharmacol. 2018 Apr 15;345:1-9.

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