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2299-91-4,MFCD00013166
Catalog No.:AA01X4L9

2299-91-4 | Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-, phosphate

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01X4L9
Chemical Name:
Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-, phosphate
CAS Number:
2299-91-4
Molecular Formula:
C15H24N3O5P
Molecular Weight:
357.3419
MDL Number:
MFCD00013166
SMILES:
OP(=O)(O)O.NCCCC(Nc1cc(OC)cc2c1nccc2)C
Properties
Computed Properties
 
Complexity:
312  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.

Journal: Chemico-biological interactions 20160805

Title: Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study.

Journal: Lancet (London, England) 20140322

Title: Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1-5 years of age.

Journal: The Journal of infectious diseases 20121201

Title: In vitro and in vivo evaluation of a primaquine prodrug without red blood cell membrane destabilization property.

Journal: Biopharmaceutics & drug disposition 20121101

Title: Primaquine for reducing Plasmodium falciparum transmission.

Journal: The Cochrane database of systematic reviews 20120912

Title: [Plasmodium vivax malaria recurrence according to the use of primaquine: analysis of longitudinal descriptive studies].

Journal: Revista brasileira de epidemiologia = Brazilian journal of epidemiology 20120901

Title: Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120801

Title: 'Not another UTI ... '.

Journal: Age and ageing 20120701

Title: Relapse of imported vivax malaria despite standard-dose primaquine therapy: an investigation with molecular genotyping analyses.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120701

Title: Plasmodium vivax remains responsive to chloroquine with primaquine treatment regimen: a prospective cohort study from tertiary care teaching hospital in southern India.

Journal: Tropical doctor 20120701

Title: Status of Plasmodium vivax malaria in the Republic of Korea, 2008-2009: decrease followed by resurgence.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20120701

Title: New treatment policy of malaria as a part of malaria control program in Indonesia.

Journal: Acta medica Indonesiana 20120701

Title: Use of a rhesus Plasmodium cynomolgi model to screen for anti-hypnozoite activity of pharmaceutical substances.

Journal: The American journal of tropical medicine and hygiene 20120601

Title: Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.

Journal: Acta tropica 20120501

Title: Perspectives: The missing pieces.

Journal: Nature 20120425

Title: Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.

Journal: Toxicology 20120329

Title: Novel potent metallocenes against liver stage malaria.

Journal: Antimicrobial agents and chemotherapy 20120301

Title: Biowaiver monographs for immediate-release solid oral dosage forms: primaquine phosphate.

Journal: Journal of pharmaceutical sciences 20120301

Title: Comparative analysis of in vitro rat liver metabolism of the antimalarial primaquine and a derived imidazoquine.

Journal: Drug metabolism letters 20120301

Title: Mosquito infection studies with Aotus monkeys and humans infected with the Chesson strain of Plasmodiun vivax.

Journal: The American journal of tropical medicine and hygiene 20120301

Title: Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.

Journal: Bioorganic & medicinal chemistry letters 20120215

Title: A carbamate-based approach to primaquine prodrugs: antimalarial activity, chemical stability and enzymatic activation.

Journal: Bioorganic & medicinal chemistry 20120115

Title: Defining Plasmodium falciparum treatment in South West Asia: a randomized trial comparing artesunate or primaquine combined with chloroquine or SP.

Journal: PloS one 20120101

Title: Optimising strategies for Plasmodium falciparum malaria elimination in Cambodia: primaquine, mass drug administration and artemisinin resistance.

Journal: PloS one 20120101

Title: Genotyping of Plasmodium vivax reveals both short and long latency relapse patterns in Kolkata.

Journal: PloS one 20120101

Title: Plasmodium vivax malaria relapses at a travel medicine centre in Rio de Janeiro, a non-endemic area in Brazil.

Journal: Malaria journal 20120101

Title: CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Journal: Malaria journal 20120101

Title: Focused Screening and Treatment (FSAT): a PCR-based strategy to detect malaria parasite carriers and contain drug resistant P. falciparum, Pailin, Cambodia.

Journal: PloS one 20120101

Title: Therapeutic efficacy of artemether-lumefantrine for Plasmodium vivax infections in a prospective study in Guyana.

Journal: Malaria journal 20120101

Title: Efficacy of chloroquine plus primaquine treatment and pfcrt mutation in uncomplicated falciparum malaria patients in Rangamati, Bangladesh.

Journal: Parasitology international 20111201

Title: Review: Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations.

Journal: The American journal of tropical medicine and hygiene 20111201

Title: Review: Malaria chemoprophylaxis for travelers to Latin America.

Journal: The American journal of tropical medicine and hygiene 20111201

Title: The use of artemether-lumefantrine for the treatment of uncomplicated Plasmodium vivax malaria.

Journal: PLoS neglected tropical diseases 20111201

Title: In vivo sensitivity monitoring of chloroquine for the treatment of uncomplicated vivax malaria in four bordered provinces of Thailand during 2009-2010.

Journal: Journal of vector borne diseases 20111201

Title: Plasmodium vivax malaria presenting with skin rash--a case report.

Journal: Journal of vector borne diseases 20111201

Title: Prophylactic use of antimalarials during pregnancy.

Journal: Canadian family physician Medecin de famille canadien 20111101

Title: Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy.

Journal: Antimicrobial agents and chemotherapy 20111001

Title: Evaluation of the safety and tolerability of a short higher-dose primaquine regimen for presumptive anti-relapse therapy in healthy subjects.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20111001

Title: Three unusual presentations of plasmodium vivax malaria.

Journal: Tropical doctor 20111001

Title: Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20111001

Title: Increased bioavailability of primaquine using poly(ethylene oxide) matrix extended-release tablets administered to beagle dogs.

Journal: Annals of tropical medicine and parasitology 20111001

Title: DFT study on the radical anions formed by primaquine and its derivatives.

Journal: Chemical research in toxicology 20110919

Title: Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification.

Journal: Biomedical chromatography : BMC 20110901

Title: Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes.

Journal: PLoS neglected tropical diseases 20110901

Title: A residue W756 in the P-loop segment of the sodium channel is critical for primaquine binding.

Journal: European journal of pharmacology 20110801

Title: Blood parasites mediate morph-specific maintenance costs in a colour polymorphic wild bird.

Journal: Journal of evolutionary biology 20110801

Title: A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue.

Journal: Molecular and biochemical parasitology 20110601

Title: Plasmodium knowlesi malaria in children.

Journal: Emerging infectious diseases 20110501

Title: Therapeutic efficacy of chloroquine in Plasmodium vivax and the pvmdr1 polymorphisms in the Republic of Korea under mass chemoprophylaxis.

Journal: The American journal of tropical medicine and hygiene 20110405

Title: Biochemically altered human erythrocytes as a carrier for targeted delivery of primaquine: an in vitro study.

Journal: Archives of pharmacal research 20110401

Title: Enantiomeric separation of antimalarial drugs by capillary electrophoresis using neutral and negatively charged cyclodextrins.

Journal: Journal of pharmaceutical and biomedical analysis 20110220

Title: Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.

Journal: The American journal of tropical medicine and hygiene 20110204

Title: Nest ectoparasites increase physiological stress in breeding birds: an experiment.

Journal: Die Naturwissenschaften 20110201

Title: Effects of the antimalarial drug primaquine on the dynamic structure of lipid model membranes.

Journal: Biochimica et biophysica acta 20110101

Title: Schistosoma mansoni: schistosomicidal effect of mefloquine and primaquine in vitro.

Journal: Experimental parasitology 20110101

Title: Consideration of ethics in primaquine therapy against malaria transmission.

Journal: Trends in parasitology 20110101

Title: Transfusion-related Plasmodium ovale malaria complicated by acute respiratory distress syndrome (ARDS) in a non-endemic country.

Journal: Parasitology international 20110101

Title: Evidence of the formation of direct covalent adducts of primaquine, 2-tert-butylprimaquine (NP-96) and monohydroxy metabolite of NP-96 with glutathione and N-acetylcysteine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101

Title: Variant Plasmodium ovale isolated from a patient infected in Ghana.

Journal: Malaria journal 20110101

Title: Auto-immune haemolytic anaemia concurrent with Plasmodium vivax infection: a case report.

Journal: Annals of tropical paediatrics 20110101

Title: Directly observed therapy with primaquine to reduce the recurrence rate of plasmodium vivax infection along the Thai-Myanmar border.

Journal: The Southeast Asian journal of tropical medicine and public health 20110101

Title: Monitoring of clinical efficacy and in vitro sensitivity of Plasmodium vivax to chloroquine in area along Thai Myanmar border during 2009-2010.

Journal: Malaria journal 20110101

Title: [Methemoglobinemia in patients with Plasmodium vivax receiving oral therapy with primaquine].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20110101

Title: HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction.

Journal: mBio 20110101

Title: The potential contribution of mass treatment to the control of Plasmodium falciparum malaria.

Journal: PloS one 20110101

Title: [Primaquine-induced methemoglobinaemia].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20110101

Title: A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania.

Journal: Malaria journal 20110101

Title: Primaquine in vivax malaria: an update and review on management issues.

Journal: Malaria journal 20110101

Title: Performance of the CareStart™ G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening.

Journal: PloS one 20110101

Title: Adherence to Plasmodium vivax malaria treatment in the Brazilian Amazon Region.

Journal: Malaria journal 20110101

Title: Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand.

Journal: Malaria journal 20110101

Title: Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America.

Journal: Malaria journal 20110101

Title: [Plan to improve malaria control towards its elimination in Mesoamerica].

Journal: Salud publica de Mexico 20110101

Title: Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Open channel block of the fast transient outward K+ current by primaquine and chloroquine in rat left ventricular cardiomyocytes.

Journal: European journal of pharmacology 20101125

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: [A case of malarial hepatitis by Plasmodium vivax].

Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20101101

Title: Long term primaquine administration to reduce Plasmodium falciparum gametocyte transmission in hypoendemic areas.

Journal: The Southeast Asian journal of tropical medicine and public health 20101101

Title: First autochthonous malaria case due to Plasmodium vivax since eradication, Spain, October 2010.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20101014

Title: Severe Plasmodium vivax malaria, Brazilian Amazon.

Journal: Emerging infectious diseases 20101001

Title: Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial.

Journal: The Lancet. Infectious diseases 20100909

Title: Primaquine-NSAID twin drugs: Synthesis, radical scavenging, antioxidant and Fe2+ chelating activity.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20100901

Title: Differential effects of ketoconazole and primaquine on the pharmacokinetics and tissue distribution of imatinib in mice.

Journal: Anti-cancer drugs 20100801

Title: Development and validation of a sensitive and selective UHPLC-MS/MS method for quantitation of an investigational anti-malarial compound, 2-tert-butylprimaquine (NP-96) in rat plasma, and its application in a preclinical pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20100708

Title: Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.

Journal: The American journal of tropical medicine and hygiene 20100701

Title: Adherence to 7-day primaquine treatment for the radical cure of P. vivax in the Peruvian Amazon.

Journal: The American journal of tropical medicine and hygiene 20100601

Title: Primaquine administration after falciparum malaria treatment in malaria hypoendemic areas with high incidence of falciparum and vivax mixed infection: pros and cons.

Journal: The Korean journal of parasitology 20100601

Title: Appropriate time for primaquine treatment to reduce Plasmodium falciparum transmission in hypoendemic areas.

Journal: The Korean journal of parasitology 20100601

Title: In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Blockade of hERG K(+) channel by antimalarial drug, primaquine.

Journal: Archives of pharmacal research 20100501

Title: Capillary electrophoretic separation and computational modeling of inclusion complexes of beta-cyclodextrin and 18-crown-6 ether with primaquine and quinocide.

Journal: Biomedical chromatography : BMC 20100401

Title: A comparison of two short-course primaquine regimens for the treatment and radical cure of Plasmodium vivax malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 20100401

Title: Symmetrical peripheral gangrene in childhood falciparum malaria.

Journal: International journal of dermatology 20100301

Title: Therapeutic efficacy of chloroquine and chloroquine plus primaquine for the treatment of Plasmodium vivax in Ethiopia.

Journal: Acta tropica 20100201

Title: Retinal hemorrhage in Plasmodium vivax malaria.

Journal: The American journal of tropical medicine and hygiene 20100201

Title: Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes.

Journal: Malaria journal 20100101

Title: Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine.

Journal: Malaria journal 20100101

Title: [Vivax malaria with long incubation period, detected in the Federal District: three case reports].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20100101

Title: Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs.

Journal: Malaria journal 20100101

Title: Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections.

Journal: Malaria journal 20100101

Title: Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20100101

Title: Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border.

Journal: Malaria journal 20100101

Title: The monitoring of hematopoietic stem cell transplant donors and recipients from endemic areas for malaria.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20100101

Title: Pravastatin provides antioxidant activity and protection of erythrocytes loaded Primaquine.

Journal: International journal of medical sciences 20100101

Title: Establishment of an in vitro assay for assessing the effects of drugs on the liver stages of Plasmodium vivax malaria.

Journal: PloS one 20100101

Title: Subdoses of primaquine in overweight patients and malaria vivax relapses: report of two cases in the Federal District, Brazil.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20100101

Title: The reality of using primaquine.

Journal: Malaria journal 20100101

Title: [Widespread use of primaquine for control of Plasmodium vivax epidemics in a population with varying degrees of G6PD deficiency].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20100101

Title: Malaria: prevention in travellers.

Journal: BMJ clinical evidence 20100101

Title: Anti-tumoral activity of imidazoquines, a new class of antimalarials derived from primaquine.

Journal: Bioorganic & medicinal chemistry letters 20091215

Title: Recurrence rate of vivax malaria in the Republic of Korea.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20091201

Title: Clinical efficacy of first- and second-line treatments for HIV-associated Pneumocystis jirovecii pneumonia: a tri-centre cohort study.

Journal: The Journal of antimicrobial chemotherapy 20091201

Title: Recurrent parasitemias and population dynamics of Plasmodium vivax polymorphisms in rural Amazonia.

Journal: The American journal of tropical medicine and hygiene 20091201

Title: Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.

Journal: Toxicology and applied pharmacology 20091115

Title: Prevention of Plasmodium vivax malaria recurrence: efficacy of the standard total dose of primaquine administered over 3 days.

Journal: Acta tropica 20091101

Title: Sex affects the steady-state pharmacokinetics of primaquine but not doxycycline in healthy subjects.

Journal: The American journal of tropical medicine and hygiene 20091101

Title: Successful treatment of severe pneumocystis pneumonia with clindamycin-primaquine in an HIV-negative patient.

Journal: Southern medical journal 20091101

Title: Drugs for preventing malaria in travellers.

Journal: The Cochrane database of systematic reviews 20091007

Title: Biological resistance of hydroxychloroquine for Plasmodium vivax malaria in the Republic of Korea.

Journal: The American journal of tropical medicine and hygiene 20091001

Title: Clindamycin-primaquine versus pentamidine for the second-line treatment of pneumocystis pneumonia.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20091001

Title: [Update on primaquine].

Journal: Medecine tropicale : revue du Corps de sante colonial 20091001

Title: Clinical and laboratory features of human Plasmodium knowlesi infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090915

Title: Factors affecting Culicoides species composition and abundance in avian nests.

Journal: Parasitology 20090801

Title: Urea and carbamate derivatives of primaquine: synthesis, cytostatic and antioxidant activities.

Journal: Bioorganic & medicinal chemistry 20090801

Title: [Malaria--current diagnosis and therapy].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20090715

Title: Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region.

Journal: Toxicology 20090630

Title: Voltammetric determination of some anti-malarial drugs using a carbon paste electrode modified with Cu(OH)2 nano-wire.

Journal: Talanta 20090615

Title: Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs.

Journal: European journal of medicinal chemistry 20090601

Title: The participation of secondary clinical episodes in the epidemiology of vivax malaria during pre- and post-implementation of focal control in the state of Oaxaca, Mexico.

Journal: The American journal of tropical medicine and hygiene 20090601

Title: Monkey malaria in humans: a diagnostic dilemma with conflicting laboratory data.

Journal: The American journal of tropical medicine and hygiene 20090601

Title: [Therapeutic efficacy of a regimen of artesunate-mefloquine-primaquine treatment for Plasmodium falciparum malaria and treatment effects on gametocytic development].

Journal: Biomedica : revista del Instituto Nacional de Salud 20090601

Title: Determination of quinocide as impurity in primaquine tablets by capillary zone electrophoresis.

Journal: Biomedical chromatography : BMC 20090501

Title: Antimalarial drugs and heme in detergent micelles: An NMR study.

Journal: Journal of inorganic biochemistry 20090501

Title: Central retinal vein occlusion in an Army ranger with glucose-6-phosphate dehydrogenase deficiency.

Journal: Military medicine 20090501

Title: Photoreactivity of biologically active compounds. XIX: excited states and free radicals from the antimalarial drug primaquine.

Journal: Journal of photochemistry and photobiology. B, Biology 20090303

Title: Enantioselective analysis of primaquine and its impurity quinocide by capillary electrophoresis.

Journal: Biomedical chromatography : BMC 20090301

Title: Primaquine revisited six decades after its discovery.

Journal: European journal of medicinal chemistry 20090301

Title: Macromolecular prodrugs. XII. Primaquine conjugates: synthesis and preliminary antimalarial evaluation.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20090301

Title: Methemoglobinemia and adverse events in Plasmodium vivax malaria patients associated with high doses of primaquine treatment.

Journal: The American journal of tropical medicine and hygiene 20090201

Title: Analysis of quinocide in unprocessed primaquine diphosphate and primaquine diphosphate tablets using gas chromatography-mass spectrometry with supersonic molecular beams.

Journal: Journal of chromatography. A 20090130

Title: Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populations.

Journal: Malaria journal 20090101

Title: Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives.

Journal: European journal of mass spectrometry (Chichester, England) 20090101

Title: Determination of the Plasmodium vivax relapse pattern in Camopi, French Guiana.

Journal: Malaria journal 20090101

Title: [Efficiency of a package of therapeutic and preventive measures in the Republic of Tajikistan in the malaria postepidemic period (2000-2007)].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20090101

Title: Identification of differentially expressed genes after acute exposure to bulaquine (CDRI 80/53) in mice liver.

Journal: Basic & clinical pharmacology & toxicology 20081201

Title: The efficacy and tolerability of three different regimens of tafenoquine versus primaquine for post-exposure prophylaxis of Plasmodium vivax malaria in the Southwest Pacific.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101

Title: Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine.

Journal: Journal of the American Society for Mass Spectrometry 20081001

Title: Formulation and evaluation of primaquine phosphate taste-masked rapidly disintegrating tablet.

Journal: The Journal of pharmacy and pharmacology 20081001

Title: Protection of retinal cells from ischemia by a novel gap junction inhibitor.

Journal: Biochemical and biophysical research communications 20080905

Title: Formulation and evaluation of taste masked oral reconstitutable suspension of primaquine phosphate.

Journal: AAPS PharmSciTech 20080901

Title: Acute respiratory distress syndrome in a case of Plasmodium ovale malaria.

Journal: The American journal of tropical medicine and hygiene 20080901

Title: Toxicity in rhesus monkeys following administration of the 8-aminoquinoline 8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline (WR242511).

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080901

Title: Design, synthesis, and biological activities of conformationally restricted analogs of primaquine with a 1,10-phenanthroline framework.

Journal: Bioorganic & medicinal chemistry letters 20080815

Title: Clinical practice. Malaria prevention in short-term travelers.

Journal: The New England journal of medicine 20080807

Title: Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity.

Journal: Bioorganic & medicinal chemistry letters 20080715

Title: The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations.

Journal: European journal of medicinal chemistry 20080601

Title: [Plasmodium vivax malaria in the Brazilian Amazon: some aspects of its epidemiology, clinical spectrum and naturally induced immune responses].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20080601

Title: Second-line salvage treatment of AIDS-associated Pneumocystis jirovecii pneumonia: a case series and systematic review.

Journal: Journal of acquired immune deficiency syndromes (1999) 20080501

Title: Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation.

Journal: Nature immunology 20080501

Title: A woman from Honduras with a painful forearm and fever.

Journal: The American journal of tropical medicine and hygiene 20080501

Title: High-dose primaquine regimens against relapse of Plasmodium vivax malaria.

Journal: The American journal of tropical medicine and hygiene 20080501

Title: Synthesis and total 1H- and 13C-NMR assignment of cephem derivatives for use in ADEPT approaches.

Journal: Molecules (Basel, Switzerland) 20080410

Title: Selective plasma protein binding of antimalarial drugs to alpha1-acid glycoprotein.

Journal: Bioorganic & medicinal chemistry 20080401

Title: Alteration of platelet counts and lipid profiles after treatment of acute Plasmodium vivax.

Journal: Acta tropica 20080401

Title: [New use of primaquine for malaria].

Journal: Medecine et maladies infectieuses 20080401

Title: Formulation, antimalarial activity and biodistribution of oral lipid nanoemulsion of primaquine.

Journal: International journal of pharmaceutics 20080122

Title: Development and validation of UPLC method for determination of primaquine phosphate and its impurities.

Journal: Journal of pharmaceutical and biomedical analysis 20080122

Title: Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones.

Journal: Bioorganic & medicinal chemistry letters 20080115

Title: Atypical Plasmodium vivax malaria in a traveler: bilateral hydronephrosis, severe thrombocytopenia, and hypotension.

Journal: Journal of travel medicine 20080101

Title: [In vitro dissolution profile of primaquine tablets available for malaria treatment in Brazil].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20080101

Title: [The current malaria situation in Tadjikistan].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20080101

Title: Development of a capillary electrophoresis method for the enantioselective estimation of primaquine in pharmaceutical formulations.

Journal: Journal of AOAC International 20080101

Title: Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20080101

Title: A randomised trial of an eight-week, once weekly primaquine regimen to prevent relapse of plasmodium vivax in Northwest Frontier Province, Pakistan.

Journal: PloS one 20080101

Title: Intracellular processing of riboflavin in human breast cancer cells.

Journal: Molecular pharmaceutics 20080101

Title: [Experience in sanitizing an urban focus of vivax malaria (Tashkumyr, Kyrghyzstan)].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20080101

Title: Targeting the plasmepsin 4 orthologs of Plasmodium sp. with 'double drug' inhibitors.

Journal: Protein and peptide letters 20080101

Title: Chronic Plasmodium vivax infection in a patient with splenomegaly and severe thrombocytopenia.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20080101

Title: The role of anti-malarial drugs in eliminating malaria.

Journal: Malaria journal 20080101

Title: Synthesis and evaluation of naphthyridine compounds as antimalarial agents.

Journal: Bioorganic & medicinal chemistry letters 20071115

Title: Neglect of Plasmodium vivax malaria.

Journal: Trends in parasitology 20071101

Title: Clinical inquiries. When should travelers begin malaria prophylaxis?

Journal: The Journal of family practice 20071101

Title: Apparent relapse of imported Plasmodium ovale malaria in a pregnant woman.

Journal: The American journal of tropical medicine and hygiene 20071101

Title: Congenital malaria in the United States: a review of cases from 1966 to 2005.

Journal: Archives of pediatrics & adolescent medicine 20071101

Title: Recent patent reviews on small molecule-based antimalarial drugs.

Journal: Recent patents on anti-infective drug discovery 20071101

Title: Exploring biosynthetic diversity with trichodiene synthase.

Journal: Archives of biochemistry and biophysics 20071015

Title: Pulmonary edema due to Plasmodium vivax malaria in an American missionary.

Journal: Infection 20071001

Title: Primaquine-induced differential gene expression analysis in mice liver using DNA microarrays.

Journal: Toxicology 20070924

Title: Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum.

Journal: Blood 20070915

Title: Management of vivax malaria with primaquine.

Journal: The Journal of infection 20070901

Title: Clinical signs and response to primaquine in falcons with Haemoproteus tinnunculi infection.

Journal: The Veterinary record 20070811

Title: Role of calcium messenger systems in ACTH-induced cortisol production in bovine adrenal fasciculo-reticularis cells.

Journal: Endocrine journal 20070801

Title: Methaemoglobinaemia causing progressive dyspnoea and cyanosis during treatment of Pneumocystis jirovecii pneumonia.

Journal: International journal of STD & AIDS 20070801

Title: In Vitro and In Vivo pharmacokinetic studies of bulaquine (analogue of primaquine), a novel antirelapse antimalarial, in rat, rabbit and monkey--highlighting species similarities and differences.

Journal: Biopharmaceutics & drug disposition 20070701

Title: Chloroquine-resistant Plasmodium vivax, Brazilian Amazon.

Journal: Emerging infectious diseases 20070701

Title: Vivax malaria: preliminary observations following a shorter course of treatment with artesunate plus primaquine.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20070601

Title: Clinical efficacy of chloroquine versus artemether-lumefantrine for Plasmodium vivax treatment in Thailand.

Journal: The Korean journal of parasitology 20070601

Title: Unanticipated stereoselectivity in the reaction of primaquine alpha-aminoamides with substituted benzaldehydes: a computational and experimental study.

Journal: The Journal of organic chemistry 20070525

Title: Controversies and misconceptions in malaria chemoprophylaxis for travelers.

Journal: JAMA 20070523

Title: Can the host immune system promote multiple invasions of erythrocytes in vivo? Differential effects of medication and host sex in a wild malaria-like model.

Journal: Parasitology 20070501

Title: Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.

Journal: The Journal of infectious diseases 20070401

Title: A background and critical analysis of the treatment of pneumocystis carinii pneumonia (PCP) in HIV/AIDS.

Journal: Australian nursing journal (July 1993) 20070401

Title: Management of vivax malaria with low sensitivity to primaquine.

Journal: The Journal of infection 20070301

Title: A case of symptomatic splenic infarction in vivax malaria.

Journal: The Korean journal of parasitology 20070301

Title: Nature of the main contaminant in the drug primaquine diphosphate: SFC and SFC-MS methods of analysis.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: When the book is wrong.

Journal: Lancet (London, England) 20070203

Title: A rare glimpse at the efficacy of primaquine.

Journal: The American journal of tropical medicine and hygiene 20070201

Title: Regional differences in the response of Plasmodium vivax malaria to primaquine as anti-relapse therapy.

Journal: The American journal of tropical medicine and hygiene 20070201

Title: Primaquine for preventing relapses in people with Plasmodium vivax malaria.

Journal: The Cochrane database of systematic reviews 20070124

Title: Self-gelling primaquine-gum arabic conjugate: an injectable controlled delivery system for primaquine.

Journal: Biomacromolecules 20070101

Title: Operational feasibility of rapid diagnostic kits & blister packs use for malaria control in high transmission areas of Orissa & Chhattisgarh.

Journal: The Indian journal of medical research 20070101

Title: Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.

Journal: PloS one 20070101

Title: [Association of methemoglobinemia and glucose-6-phosphate dehydrogenase deficiency in malaria patients treated with primaquine].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20070101

Title: Relapsing vivax malaria after 6 months of daily atovaquone/proguanil in Afghanistan: the case for expanded use of primaquine as a causal prophylactic.

Journal: Journal of travel medicine 20070101

Title: Photophysical properties and photobiological behavior of amodiaquine, primaquine and chloroquine.

Journal: Photochemistry and photobiology 20070101

Title: A randomized open-label trial of artesunate- sulfadoxine-pyrimethamine with or without primaquine for elimination of sub-microscopic P. falciparum parasitaemia and gametocyte carriage in eastern Sudan.

Journal: PloS one 20070101

Title: Plasmodium vivax malaria relapses after primaquine prophylaxis.

Journal: Emerging infectious diseases 20061101

Title: Glucose 6-phosphate dehydrogenase deficiency: from genotype to phenotype.

Journal: Haematologica 20061001

Title: Efficacy of three chloroquine-primaquine regimens for treatment of Plasmodium vivax malaria in Colombia.

Journal: The American journal of tropical medicine and hygiene 20061001

Title: Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I.

Journal: The American journal of tropical medicine and hygiene 20060901

Title: Cost considerations of malaria chemoprophylaxis including use of primaquine for primary or terminal chemoprophylaxis.

Journal: The American journal of tropical medicine and hygiene 20060901

Title: Safety and tolerability of elubaquine (bulaquine, CDRI 80/53) for treatment of Plasmidium vivax malaria in Thailand.

Journal: The Korean journal of parasitology 20060901

Title: Prevalence of glucose-6-phosphate dehydrogenase deficiency in U.S. Army personnel.

Journal: Military medicine 20060901

Title: [Plasmodium vivax malaria: treatment of primary attacks with primaquine, in three different doses, and a fixed dose of chloroquine, Antioquia, Colombia, 2003-2004].

Journal: Biomedica : revista del Instituto Nacional de Salud 20060901

Title: A simple technique for the detection of anti-malarial drug formulations and their presence in human urine.

Journal: Tanzania health research bulletin 20060901

Title: Imported non-Plasmodium falciparum malaria: a five-year prospective study in a European referral center.

Journal: The American journal of tropical medicine and hygiene 20060701

Title: Chloroquine and primaquine: combining old drugs as a new weapon against falciparum malaria?

Journal: Trends in parasitology 20060601

Title: Cerebral malaria owing to Plasmodium vivax: case report.

Journal: Annals of tropical paediatrics 20060601

Title: Does gender, food or grapefruit juice alter the pharmacokinetics of primaquine in healthy subjects?

Journal: British journal of clinical pharmacology 20060601

Title: Lack of sex effect on the pharmacokinetics of primaquine.

Journal: The American journal of tropical medicine and hygiene 20060601

Title: Pneumocystis pneumonia in people with HIV.

Journal: Clinical evidence 20060601

Title: Pharmacokinetics of piperaquine after repeated oral administration of the antimalarial combination CV8 in 12 healthy male subjects.

Journal: European journal of clinical pharmacology 20060501

Title: [Haemolysis due to primaquine in 3 cases].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20060227

Title: Do apoptotic Plasmodium-infected hepatocytes initiate protective immune responses?

Journal: The Journal of infectious diseases 20060101

Title: Are multiple gametocyte infections in malarial parasites an adaptation to ensure fertility?

Journal: Parasitology 20060101

Title: A randomized, parallel study of the safety and efficacy of 45 mg primaquine versus 75 mg bulaquine as gametocytocidal agents in adults with blood schizonticide-responsive uncomplicated falciparum malaria [ISCRTN50134587].

Journal: BMC infectious diseases 20060101

Title: [How much primaquine is needed to eradicate Plasmodium vivax hypnozoites?].

Journal: Enfermedades infecciosas y microbiologia clinica 20060101

Title: Frequency of malaria and glucose-6-phosphate dehydrogenase deficiency in Tajikistan.

Journal: Malaria journal 20060101

Title: Combined chloroquine, sulfadoxine/pyrimethamine and primaquine against Plasmodium falciparum in Central Java, Indonesia.

Journal: Malaria journal 20060101

Title: Primaquine-induced hemolytic anemia: role of splenic macrophages in the fate of 5-hydroxyprimaquine-treated rat erythrocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20051201

Title: A double-blind, randomized study of azithromycin compared to chloroquine for the treatment of Plasmodium vivax malaria in India.

Journal: The American journal of tropical medicine and hygiene 20051201

Title: A 57-year-old man with a 6-day headache and fatigue.

Journal: The American journal of medicine 20051201

Title: Failure of primaquine therapy for the treatment of Plasmodium ovale malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051115

Title: Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum.

Journal: Biochemical pharmacology 20051015

Title: Targeting primaquine into liver using chylomicron emulsions for potential vivax malaria therapy.

Journal: International journal of pharmaceutics 20051013

Title: Evaluation of anti-malarial effects of mass chemoprophylaxis in the Republic of Korea army.

Journal: Journal of Korean medical science 20051001

Title: Application of GC-EI-MS for the identification and investigation of positional isomer in primaquine, an antimalarial drug.

Journal: Journal of pharmaceutical and biomedical analysis 20050901

Title: Plasmodium cynomolgi: gametocytocidal activity of the anti-malarial compound CDRI 80/53 (elubaquine) in rhesus monkeys.

Journal: Experimental parasitology 20050901

Title: Primaquine-induced hemolytic anemia: role of membrane lipid peroxidation and cytoskeletal protein alterations in the hemotoxicity of 5-hydroxyprimaquine.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: Pseudo-borreliosis in patients with malaria.

Journal: The American journal of tropical medicine and hygiene 20050701

Title: Photoreactivity of biologically active compounds. XVII. Influence of solvent interactions on spectroscopic properties and photostability of primaquine.

Journal: Die Pharmazie 20050601

Title: Pneumocystis pneumonia in people with HIV.

Journal: Clinical evidence 20050601

Title: Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting.

Journal: International journal of pharmaceutics 20050513

Title: Effectiveness of antimalarial drugs.

Journal: The New England journal of medicine 20050414

Title: A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes.

Journal: Journal of pharmaceutical and biomedical analysis 20050401

Title: Glucose-6-phosphate dehydrogenase deficiency in two returning Operation Iraqi Freedom soldiers who developed hemolytic anemia while receiving primaquine prophylaxis for malaria.

Journal: Military medicine 20050401

Title: Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro.

Journal: Journal of clinical pharmacology 20050301

Title: Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials.

Journal: Journal of medicinal chemistry 20050210

Title: Raising antibodies in chickens against primaquine, pyrimethamine, dapsone, tetracycline, and doxycycline.

Journal: Immunological investigations 20050101

Title: Diagnostic and prognostic utility of an inexpensive rapid on site malaria diagnostic test (ParaHIT f) among ethnic tribal population in areas of high, low and no transmission in central India.

Journal: BMC infectious diseases 20050101

Title: Adequate primaquine for vivax malaria.

Journal: Journal of travel medicine 20050101

Title: Glucose-6-phosphate dehydrogenase (G6PD) mutations in Cambodia: G6PD Viangchan (871G>A) is the most common variant in the Cambodian population.

Journal: Journal of human genetics 20050101

Title: Antimalarials inhibit human erythrocyte membrane acetylcholinesterase.

Journal: Drug and chemical toxicology 20050101

Title: Primaquine therapy for malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041101

Title: Randomized trial of 3-dose regimens of tafenoquine (WR238605) versus low-dose primaquine for preventing Plasmodium vivax malaria relapse.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041015

Title: Declining mefloquine sensitivity of Plasmodium falciparum along the Thai-Myanmar border.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Assessment of therapeutic efficacy of chloroquine for vivax malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Therapeutic efficacy of artesunate in Plasmodium vivax malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Changes in Haemoproteus sex ratios: fertility insurance or differential sex lifespan?

Journal: Proceedings. Biological sciences 20040807

Title: Enantioselective analysis of primaquine and its metabolite carboxyprimaquine by capillary electrophoresis.

Journal: Electrophoresis 20040801

Title: PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions.

Journal: The EMBO journal 20040707

Title: A prospective study evaluating the efficacy of a single, 45-mg dose of primaquine, as a gametocytocidal agent, in patients with Plasmodium falciparum malaria in Mumbai, India.

Journal: Annals of tropical medicine and parasitology 20040701

Title: Preliminary report of the evaluation of the gametocytocidal action of bulaquine, in adult patients with acute, Plasmodium falciparum malaria.

Journal: Annals of tropical medicine and parasitology 20040701

Title: Plasmepsin II inhibition and antiplasmodial activity of Primaquine-Statine 'double-drugs'.

Journal: Bioorganic & medicinal chemistry letters 20040607

Title: In vitro and in vivo evaluation of albumin-encapsulated primaquine diphosphate prepared by nebulization into heated oil.

Journal: Journal of microencapsulation 20040601

Title: Pneumocystis carinii pneumonia treatment in people infected with HIV.

Journal: Clinical evidence 20040601

Title: Pharmacokinetics of primaquine and carboxyprimaquine in Korean patients with vivax malaria.

Journal: Archives of pharmacal research 20040501

Title: Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines.

Journal: Biochemistry 20040420

Title: Primaquine-induced hemolytic anemia: susceptibility of normal versus glutathione-depleted rat erythrocytes to 5-hydroxyprimaquine.

Journal: The Journal of pharmacology and experimental therapeutics 20040401

Title: A large focus of naturally acquired Plasmodium knowlesi infections in human beings.

Journal: Lancet (London, England) 20040327

Title: Synthesis and blood-schizontocidal antimalarial activities of 2-substituted/2,5-disubstituted-8-quinolinamines and some of their amino acid conjugates.

Journal: Bioorganic & medicinal chemistry 20040301

Title: Compliance with 14-day primaquine therapy for radical cure of vivax malaria--a randomized placebo-controlled trial comparing unsupervised with supervised treatment.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20040301

Title: Nature of the main contaminant in the anti malaria drug primaquine diphosphate: a qualitative isomer analysis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040205

Title: Treatment with antimalarials adversely affects the oxidative energy metabolism in rat liver mitochondria.

Journal: Drug and chemical toxicology 20040201

Title: CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam.

Journal: Tropical medicine & international health : TM & IH 20040201

Title: Discovery of a bulky 2-tert-butyl group containing primaquine analogue that exhibits potent blood-schizontocidal antimalarial activities and complete elimination of methemoglobin toxicity.

Journal: Journal of medicinal chemistry 20040115

Title: [Cerebral Malaria in Ceará: a case report].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20040101

Title: Preparation and in vitro evaluation of primaquine-conjugated gum arabic microspheres.

Journal: Biomacromolecules 20040101

Title: [Clinical and laboratorial alterations in Plasmodium vivax malaria patients and glucose-6-phosphate dehydrogenase deficiency treated with primaquine at 0.50 mg/kg/day].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20040101

Title: Primaquine for prevention of malaria in travelers.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031215

Title: Military aviators, special operations forces, and causal malaria prophylaxis.

Journal: Military medicine 20031201

Title: HPLC and HPTLC assays for the antimalarial agents chloroquine, primaquine and bulaquine.

Journal: Journal of pharmaceutical and biomedical analysis 20031124

Title: Transmission-blocking activity of tafenoquine (WR-238605) and artelinic acid against naturally circulating strains of Plasmodium vivax in Thailand.

Journal: The American journal of tropical medicine and hygiene 20031101

Title: Mechanism of C2-toxin inhibition by fluphenazine and related compounds: investigation of their binding kinetics to the C2II-channel using the current noise analysis.

Journal: Journal of molecular biology 20031024

Title: Two worlds of malaria.

Journal: The New England journal of medicine 20031016

Title: Real-time investigation of the interaction between primaquine phosphate and bovine serum albumin (BSA) by piezoelectric quartz crystal impedance analysis.

Journal: Journal of biotechnology 20031009

Title: Problems in the therapy for imported malaria in the United States.

Journal: Archives of internal medicine 20030922

Title: Clinical efficacy of chloroquine followed by primaquine for Plasmodium vivax treatment in Azerbaijan.

Journal: Acta tropica 20030901

Title: Monitoring the therapeutic efficacy of antimalarials against uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: Liquid chromatography-tandem mass spectrometric assay with a novel method of quantitation for the simultaneous determination of bulaquine and its metabolite, primaquine, in monkey plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030815

Title: Cooperative actions to achieve malaria control without the use of DDT.

Journal: International journal of hygiene and environmental health 20030801

Title: Vivax malaria: a continuing health threat to the Republic of Korea.

Journal: The American journal of tropical medicine and hygiene 20030801

Title: The impact of Malarone and primaquine on psychomotor performance.

Journal: Aviation, space, and environmental medicine 20030701

Title: Clinical trial of oral artesunate with or without high-dose primaquine for the treatment of vivax malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 20030701

Title: Primaquine induced methemoglobinemia.

Journal: Indian journal of pediatrics 20030601

Title: Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20030601

Title: Binding of primaquine to epidermal membranes and keratin.

Journal: International journal of pharmaceutics 20030512

Title: The efficacy of combined mefloquine-artesunate versus mefloquine-primaquine on subsequent development of Plasmodium falciparum gametocytemia.

Journal: The American journal of tropical medicine and hygiene 20030501

Title: Analysis and pharmacokinetics of bulaquine and its major metabolite primaquine in rabbits using an LC-UV method--a pilot study.

Journal: Journal of pharmaceutical and biomedical analysis 20030424

Title: Presentation by recycling MHC class II molecules of an influenza hemagglutinin-derived epitope that is revealed in the early endosome by acidification.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030401

Title: Toxicity related to chloroquine treatment of resistant vivax malaria.

Journal: The Annals of pharmacotherapy 20030401

Title: Blood schizontocidal activity of WR 238605 (Tafenoquine) against Plasmodium cynomolgi and Plasmodium fragile infections in rhesus monkeys.

Journal: Acta tropica 20030401

Title: The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines.

Journal: Annals of tropical medicine and parasitology 20030401

Title: A mathematical model for the transmission of Plasmodium vivax malaria.

Journal: Parasitology international 20030301

Title: Can primaquine therapy for vivax malaria be improved?

Journal: Trends in parasitology 20030301

Title: Efficacy of a five-day course of primaquine in preventing relapses in Plasmodium vivax malaria--a pilot study.

Journal: The Ceylon medical journal 20030301

Title: Case report: An unusual late relapse of Plasmodium vivax malaria.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: [Antiprotozoal drugs].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030201

Title: [Short course schemes for vivax malaria treatment].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20030101

Title: [Internal validity of clinical trials for Plasmodium vivax malaria treatment: analysis of evaluation study of in vivo Plasmodium vivax emergence of resistance to standard doses of primaquine].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20030101

Title: Efficacy of a 14-day primaquine regimen in preventing relapses in patients with Plasmodium vivax malaria in Mumbai, India.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Effectiveness of primaquine terminal prophylaxis against late primary attacks of Plasmodium vivax malaria: a case-control study among troops of the Republic of Korea army.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Isolation and antimalarial activity of peroxydisulfate oxidation products of primaquine.

Journal: Bioorganic & medicinal chemistry letters 20021216

Title: Discovery of novel targets of quinoline drugs in the human purine binding proteome.

Journal: Molecular pharmacology 20021201

Title: Primaquine-induced hemolytic anemia: formation of free radicals in rat erythrocytes exposed to 6-methoxy-8-hydroxylaminoquinoline.

Journal: The Journal of pharmacology and experimental therapeutics 20021201

Title: Plasmodium ovale malaria acquired in central Spain.

Journal: Emerging infectious diseases 20021201

Title: The clinical and epidemiological features of childhood malaria in a moderately endemic area of Sri Lanka.

Journal: The Southeast Asian journal of tropical medicine and public health 20021201

Title: Cytochrome P450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells.

Journal: European journal of clinical pharmacology 20021101

Title: Pancytopenia resulting from hemophagocytosis in malaria.

Journal: The Pediatric infectious disease journal 20021101

Title: Primaquine-induced hemolytic anemia: effect of 6-methoxy-8-hydroxylaminoquinoline on rat erythrocyte sulfhydryl status, membrane lipids, cytoskeletal proteins, and morphology.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Radical curative efficacy of five-day regimen of primaquine for treatment of Plasmodium vivax malaria in India.

Journal: The Journal of parasitology 20021001

Title: Sensitivity of Plasmodium vivax to chloroquine in Sa Kaeo Province, Thailand.

Journal: Acta tropica 20020801

Title: Does radical cure of asymptomatic Plasmodium falciparum place adults in endemic areas at increased risk of recurrent symptomatic malaria?

Journal: Tropical medicine & international health : TM & IH 20020701

Title: Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020601

Title: Coronary bypass surgery in patient with malaria.

Journal: Asian cardiovascular & thoracic annals 20020601

Title: Short report: therapeutic efficacy of chloroquine combined with primaquine against Plasmodium falciparum in northeastern Papua, Indonesia.

Journal: The American journal of tropical medicine and hygiene 20020601

Title: Relapsing vivax malaria.

Journal: The Medical journal of Australia 20020520

Title: Enantiomeric separation of primaquine, an anti-malarial drug, by cyclodextrin-modified micellar electrokinetic capillary chromatography.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020501

Title: Effect of antimalarial drugs on plasmodia cell-free protein synthesis.

Journal: Memorias do Instituto Oswaldo Cruz 20020401

Title: Relapse pattern of Plasmodium vivax in Mumbai: a study of 283 cases of vivax malaria.

Journal: The Journal of the Association of Physicians of India 20020301

Title: Methemoglobin reductase activity and in vitro sensitivity towards oxidant induced methemoglobinemia in swiss mice and beagle dogs erythrocytes.

Journal: Molecular and cellular biochemistry 20020301

Title: Prevalence of malaria in Aligarh.

Journal: The Journal of communicable diseases 20020301

Title: Inhibition of cardiac Na+ current by primaquine.

Journal: British journal of pharmacology 20020201

Title: Mutagenic activity and mutational specificity of antiprotozoal drugs with and without nitrite treatment.

Journal: Environmental and molecular mutagenesis 20020101

Title: Control of malaria: a successful experience from Viet Nam.

Journal: Bulletin of the World Health Organization 20020101

Title: Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria in Australian Defence Force personnel.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: Randomized, parallel placebo-controlled trial of primaquine for malaria prophylaxis in Papua, Indonesia.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011215

Title: Effect of primaquine standard dose (15 mg/day for 14 days) in the treatment of vivax malaria patients in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20011201

Title: Current drugs for antimalarial chemoprophylaxis: a review of efficacy and safety.

Journal: Journal of travel medicine 20011201

Title: Association of subtherapeutic dosages of a standard drug regimen with failures in preventing relapses of vivax malaria.

Journal: The American journal of tropical medicine and hygiene 20011101

Title: Plasmodium vivax relapses after 5 days of primaquine treatment, in some industrial complexes of India.

Journal: Annals of tropical medicine and parasitology 20011001

Title: Plasmodium vivax polymorphism in a clinical drug trial.

Journal: Clinical and diagnostic laboratory immunology 20010901

Title: Malaria chemoprophylaxis in the age of drug resistance. II. Drugs that may be available in the future.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010801

Title: Plasmodium vivax clinically resistant to chloroquine in Colombia.

Journal: The American journal of tropical medicine and hygiene 20010801

Title: Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010715

Title: The antileishmanial properties of surface-modified, primaquine-loaded nanocapsules tested against intramacrophagic Leishmania donovani amastigotes in vitro.

Journal: Annals of tropical medicine and parasitology 20010701

Title: Treating malaria may be too expensive.

Journal: Australian family physician 20010601

Title: Primaquine-induced hemolytic anemia: formation and hemotoxicity of the arylhydroxylamine metabolite 6-methoxy-8-hydroxylaminoquinoline.

Journal: The Journal of pharmacology and experimental therapeutics 20010501

Title: Transcriptional and post-translational regulation of CYP1A1 by primaquine.

Journal: The Journal of pharmacology and experimental therapeutics 20010401

Title: Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy.

Journal: Diabetologia 20010401

Title: Functional integrity of the vesicle transporting machinery is required for complete activation of cFTR expressed in xenopus laevis oocytes.

Journal: Pflugers Archiv : European journal of physiology 20010301

Title: [Does the brief treatment with antimalarials favorably influence drug resistance and recurrences?].

Journal: Revista panamericana de salud publica = Pan American journal of public health 20010301

Title: Dissociation and electrooxidation of primaquine diphosphate as an approach to the study of anti-chagas prodrugs mechanism of action.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20010101

Title: Immunological alterations associated with Plasmodium vivax malaria in South Korea.

Journal: Annals of tropical medicine and parasitology 20010101

Title: Antimalarial chemoprophylaxis in infants and children.

Journal: Paediatric drugs 20010101

Title: [Primaquine].

Journal: Medecine tropicale : revue du Corps de sante colonial 20010101

Title: Malaria prophylaxis/radical cure: recent experiences of the Australian Defence Force.

Journal: Medecine tropicale : revue du Corps de sante colonial 20010101

Title: [Effect of daphnetin on the exo-erythrocytic stage of rodent malaria].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20010101

Title: [A study of artemether combined with primaquine in the treatment of falciparum malaria].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20010101

Title: [Hemolysis and primaquine treatment. Preliminary report].

Journal: Revista cubana de medicina tropical 19970101

Title: Dapsone- and primaquine-induced methemoglobinemia in HIV-infected individuals.

Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19960815

Title: [Primaquine and travelers from the Arab world. A report and recommendations].

Journal: Revista cubana de medicina tropical 19950101

Title: In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii.

Journal: Antimicrobial agents and chemotherapy 19940601

Title: [Comparative study on hemolytic toxicity of trifluoroacetoprimaquine and primaquine in rabbits].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 19940101

Title: Acute intravascular haemolysis in Vanuatu following a single dose of primaquine in individuals with glucose-6-phosphate dehydrogenase deficiency.

Journal: The Journal of tropical medicine and hygiene 19921001

Title: 8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models.

Journal: Antimicrobial agents and chemotherapy 19910201

Title: The effect of primaquine on the ultrastructural morphology of Pneumocystis carinii.

Journal: The Journal of protozoology 19910101

Title: Detection of antidrug IgG antibodies in patients with adverse drug reactions to amodiaquine.

Journal: International archives of allergy and applied immunology 19910101

Title: Primaquine induced hemolysis in a Thai soldier.

Journal: The Southeast Asian journal of tropical medicine and public health 19891201

Title: Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo.

Journal: Antimicrobial agents and chemotherapy 19880601

Title: [Hemolytic reaction due to administration of primaquine].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 19860401

Title: Pharmacokinetics of primaquine in man. I. Studies of the absolute bioavailability and effects of dose size.

Journal: British journal of clinical pharmacology 19850601

Title: Primaquine-chloroquine prophylaxis against malaria in Southeast-Asian refugees entering South Australia.

Journal: The Medical journal of Australia 19840317

Title: The treatment of malaria in glucose-6-phosphate dehydrogenase deficient patients in Sabah.

Journal: Annals of tropical medicine and parasitology 19811201

Title: Reaction to primaquine.

Journal: Annals of internal medicine 19800301

Title: Antimalarial activities of various 4-quinolonemethanols with special attention to WR-142,490 (mefloquine).

Journal: Antimicrobial agents and chemotherapy 19780601

Title: Hemolysis in dialyzed patients: tap water-induced red blood cell metabolic deficiency.

Journal: Transactions - American Society for Artificial Internal Organs 19720101

Title: Simultaneous drug reactions in the same patient. Chloroquine-Primaquine sensitivity.

Journal: JAMA 19700427

Title: Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam.

Journal: The New England journal of medicine 19681121

Title: The haemolytic effect of various regimens of primaquine with chloroquine in American Negroes with G6PD deficiency and the lack of an effect of various antimalarial suppressive agents on erythrocyte metabolism.

Journal: Bulletin of the World Health Organization 19670101

Title: Potentiation of the curative action of primaquine in vivax malaria by quinine and chloroquine.

Journal: The Journal of laboratory and clinical medicine 19550801

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Tags:2299-91-4 Molecular Formula|2299-91-4 MDL|2299-91-4 SMILES|2299-91-4 Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-, phosphate