Home Amines 23047-25-8
23047-25-8,MFCD00865465
Catalog No.:AA002LXG

23047-25-8 | Lofepramine

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1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$143.00   $100.00
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10mg
≥95%
in stock  
$199.00   $139.00
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50mg
≥95%
in stock  
$762.00   $533.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002LXG
Chemical Name:
Lofepramine
CAS Number:
23047-25-8
Molecular Formula:
C26H27ClN2O
Molecular Weight:
418.9584
MDL Number:
MFCD00865465
SMILES:
CN(CC(=O)c1ccc(cc1)Cl)CCCN1c2ccccc2CCc2c1cccc2
Properties
Computed Properties
 
Complexity:
523  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
7  
XLogP3:
6.8  

Literature

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology 20171201

Title: Efficacy of antidepressants for late-life depression: a meta-analysis and meta-regression of placebo-controlled randomized trials.

Journal: The Journal of clinical psychiatry 20111201

Title: Neurotrophins role in depression neurobiology: a review of basic and clinical evidence.

Journal: Current neuropharmacology 20111201

Title: Efficacy of antidepressants for dysthymia: a meta-analysis of placebo-controlled randomized trials.

Journal: The Journal of clinical psychiatry 20110401

Title: Antidepressant use and colorectal cancer risk: a Danish population-based case-control study.

Journal: British journal of cancer 20110104

Title: Antidepressant use and risk of adverse outcomes in older people: population based cohort study.

Journal: BMJ (Clinical research ed.) 20110101

Title: Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study.

Journal: BMJ (Clinical research ed.) 20110101

Title: Intense suicidal thoughts and self-harm following escitalopram treatment.

Journal: Indian journal of psychological medicine 20110101

Title: Trazodone effects on [H]-paroxetine and alpha(2)-adrenoreceptors in platelets of patients with major depression.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Tricyclic antidepressants and headaches: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20100101

Title: Psychosocial issues in palliative care: a review of five cases.

Journal: Indian journal of palliative care 20100101

Title: Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Effect of educational outreach on general practice prescribing of antibiotics and antidepressants: a two-year randomised controlled trial.

Journal: Scandinavian journal of primary health care 20090101

Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal: Journal of medicinal chemistry 20080124

Title: Treating bipolar disorder in patients with renal failure having haemodialysis: two case reports.

Journal: Clinical practice and epidemiology in mental health : CP & EMH 20080101

Title: Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies.

Journal: Trials 20080101

Title: Neuropsychiatric manifestations of depression in multiple sclerosis: neuroinflammatory, neuroendocrine, and neurotrophic mechanisms in the pathogenesis of immune-mediated depression.

Journal: Dialogues in clinical neuroscience 20070601

Title: Inflammatory multiple-sclerosis plaques generate characteristic metabolic profiles in cerebrospinal fluid.

Journal: PloS one 20070101

Title: Is untargeted educational outreach visiting delivered by pharmaceutical advisers effective in primary care? A pragmatic randomized controlled trial.

Journal: Implementation science : IS 20070101

Title: Folate augmentation of treatment - evaluation for depression (FolATED): protocol of a randomised controlled trial.

Journal: BMC psychiatry 20070101

Title: Solid-phase extraction and analysis of 20 antidepressant drugs in human plasma by LC/MS with SSI method.

Journal: Forensic science international 20061016

Title: Cost-effectiveness and cost-utility of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine: randomised controlled trial.

Journal: The British journal of psychiatry : the journal of mental science 20060401

Title: A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine.

Journal: Health technology assessment (Winchester, England) 20050501

Title: Enhancing central noradrenergic function in depression: is there still a place for a new antidepressant?

Journal: Neuropsychiatric disease and treatment 20050301

Title: Cutaneous adverse drug reaction to oral chlorphenamine detected with patch testing.

Journal: Contact dermatitis 20050101

Title: Risk of fetal exposure to tricyclic antidepressants.

Journal: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20041001

Title: The occurrence of selected human pharmaceutical compounds in UK estuaries.

Journal: Marine pollution bulletin 20040901

Title: Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction.

Journal: Drug safety 20040101

Title: Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. A 20031010

Title: The promises and pitfalls of reboxetine.

Journal: CNS drug reviews 20030101

Title: Treatment of multiple sclerosis with lofepramine, L-phenylalanine and vitamin B(12): mechanism of action and clinical importance: roles of the locus coeruleus and central noradrenergic systems.

Journal: Medical hypotheses 20021101

Title: Managing MS. While a cure is sought, people with MS can help themselves.

Journal: Health news (Waltham, Mass.) 20021101

Title: A randomised placebo controlled exploratory study of vitamin B-12, lofepramine, and L-phenylalanine (the 'Cari Loder regime') in the treatment of multiple sclerosis.

Journal: Journal of neurology, neurosurgery, and psychiatry 20020901

Title: Nonpharmacological treatments for anxiety disorders.

Journal: Dialogues in clinical neuroscience 20020901

Title: Simultaneous determination of seven tricyclic antidepressant drugs in human plasma by direct-injection HPLC-APCI-MS-MS with an ion trap detector.

Journal: Therapeutic drug monitoring 20020801

Title: The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis.

Journal: Toxicology letters 20020310

Title: Antidepressants as risk factor for ischaemic heart disease: case-control study in primary care.

Journal: BMJ (Clinical research ed.) 20010922

Title: MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine.

Journal: Neuroreport 20010703

Title: Meta-analytical studies on new antidepressants.

Journal: British medical bulletin 20010101

Title: Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding.

Journal: Cellular and molecular neurobiology 19990801

Title: Pharmacological profile of antidepressants and related compounds at human monoamine transporters.

Journal: European journal of pharmacology 19971211

Title: Capgras syndrome in association with lithium toxicity.

Journal: The British journal of psychiatry : the journal of mental science 19911201

Title: Lancaster SG, et al. Lofepramine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs. 1989 Feb;37(2):123-40.

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