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Home Other Building Blocks 23150-65-4
23150-65-4,MFCD00038879
Catalog No.:AA002MB8

23150-65-4 | L-Glutamic acid dimethyl ester, HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10g
98%
in stock  
$7.00   $5.00
- +
25g
98%
in stock  
$13.00   $9.00
- +
100g
98%
in stock  
$44.00   $31.00
- +
500g
98%
in stock  
$159.00   $111.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002MB8
Chemical Name:
L-Glutamic acid dimethyl ester, HCl
CAS Number:
23150-65-4
Molecular Formula:
C7H14ClNO4
Molecular Weight:
211.6434
MDL Number:
MFCD00038879
SMILES:
COC(=O)CC[C@@H](C(=O)OC)N.Cl
Properties
Properties
 
Form:
Solid  
MP:
136 - 138 °C  
Refractive Index:
26 ° (C=5, H2O)  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
169  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  

Upstream Synthesis Route

[1]AngewandteChemie-InternationalEdition,2014,vol.53,#28,p.7335-7338

[2]Angew.Chem.,2014,vol.126,#28,p.7463-7466,4

[3]JournalofOrganicChemistry,2006,vol.71,#21,p.8283-8286

[4]TetrahedronLetters,2004,vol.45,#37,p.6963-6965

[5]Patent:US2012/172402,2012,A1,.Locationinpatent:Page/Pagecolumn14-15

[6]Patent:WO2004/14893,2004,A2,.Locationinpatent:Page103;105

[7]Patent:US2010/152452,2010,A1,.Locationinpatent:Page/Pagecolumn9

[8]TetrahedronLetters,2011,vol.52,#19,p.2488-2491

[9]Patent:EP2319850,2011,A1,.Locationinpatent:Page/Pagecolumn8

[10]OrganicLetters,2012,vol.14,#17,p.4518-4521

[1]JournaloftheChemicalSociety-PerkinTransactions1,1999,#10,p.1311-1323

[1]JournalofMedicinalChemistry,2007,vol.50,#24,p.6144-6153

[2]ArchivderPharmazie,2005,vol.338,#5-6,p.281-290

[3]BioorganicandMedicinalChemistry,2007,vol.15,#18,p.6273-6290

[4]BioorganicandMedicinalChemistry,2009,vol.17,#2,p.777-793

[5]Patent:CN107602436,2018,A,.Locationinpatent:Paragraph0053;0054

[6]Phytochemistry,1997,vol.45,#1,p.37-40

[7]MonatsheftefurChemie,2007,vol.138,#12,p.1283-1287

[8]JournalofOrganicChemistry,2007,vol.72,#6,p.2106-2117

[9]JournaloftheChemicalSociety-PerkinTransactions1,1999,#10,p.1311-1323

[10]Patent:EP1229041,2002,A1,.Locationinpatent:Example1

[11]Patent:WO2004/14893,2004,A2,.Locationinpatent:Page103;105

[12]Patent:US2010/152452,2010,A1,.Locationinpatent:Page/Pagecolumn9

[13]Patent:US2008/26017,2008,A1,.Locationinpatent:Page/Pagecolumn11

[14]TetrahedronLetters,2011,vol.52,#19,p.2488-2491

[15]Patent:EP2319850,2011,A1,.Locationinpatent:Page/Pagecolumn8

[16]OrganicLetters,2012,vol.14,#17,p.4518-4521

[17]JournalofMedicinalChemistry,2016,vol.59,#11,p.5505-5519

[18]BioorganicandMedicinalChemistry,2017,vol.25,#3,p.870-885

[19]RussianJournalofOrganicChemistry,2017,vol.53,#5,p.769-776

[20]Zh.Org.Khim.,2017,vol.53,#5,p.756-762,7

[21]Patent:WO2017/168442,2017,A1,.Locationinpatent:Page/Pagecolumn8;13

[22]JournalofMedicinalChemistry,2018,vol.61,#8,p.3503-3515

[1]Heterocycles,1991,vol.32,#10,p.1879-1895

[2]AminoAcids,2018,vol.50,#10,p.1461-1470

[1]Tetrahedron,2002,vol.58,#6,p.1173-1183

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1997,vol.40,p.342-349

[1]CurrentPatentAssignee:TECHNICALUNIVERSITYOFDENMARK-WO2018/37120,2018,A1Locationinpatent:Page/Pagecolumn27;32

[2]Geiger,Christian;Zelenka,Christel;Weigl,Manuela;Fröhlich,Roland;Wibbeling,Birgit;Lehmkuhl,Kirstin;Schepmann,Dirk;Grünert,Renate;Bednarski,PatrickJ.;Wünsch,Bernhard[JournalofMedicinalChemistry,2007,vol.50,#24,p.6144-6153]

[3]Jung,Bettina;Englberger,Werner;Wuensch,Bernhard[ArchivderPharmazie,2005,vol.338,#5-6,p.281-290]

[4]Gu,Keli;Bi,Lanrong;Zhao,Ming;Wang,Chao;Ju,Jingfang;Peng,Shiqi[BioorganicandMedicinalChemistry,2007,vol.15,#18,p.6273-6290]

[5]Locationinpatent:bodytextHoll,Ralph;Schepmann,Dirk;Gruenert,Renate;Bednarski,PatrickJ.;Wuensch,Bernhard[BioorganicandMedicinalChemistry,2009,vol.17,#2,p.777-793]

[6]CurrentPatentAssignee:XINFAPHARMACEUTICALCOLTD-CN107602436,2018,ALocationinpatent:Paragraph0053;0054

[7]Liakopoulou-Kyriakides;Lagopodi;Thanassoulopoulos;Stavropoulos;Magafa[Phytochemistry,1997,vol.45,#1,p.37-40]

[8]Colak,Naki;Yildirir,Yilmaz;Kavutcu,Mustafa;Nurlu,Nilhan[MonatsheftefurChemie,2007,vol.138,#12,p.1283-1287]

[9]Sureshkumar,Devarajulu;Gunasundari,Thanikachalam;Ganesh,Venkataraman;Chandrasekaran,Srinivasan[JournalofOrganicChemistry,2007,vol.72,#6,p.2106-2117]

[10]Maunder,Peter;Finglas,PaulM.;Mallet,AnthonyI.;Mellon,FredA.;AaqibRazzaque;Ridge,Brian;Vahteristo,Liisa;Witthoeft,Cornelia[JournaloftheChemicalSociety.PerkintransactionsI,1999,#10,p.1311-1323]

[11]CurrentPatentAssignee:BRACCOSPA-EP1229041,2002,A1Locationinpatent:Example1

[12]CurrentPatentAssignee:PROCTER&GAMBLECO-WO2004/14893,2004,A2Locationinpatent:Page103;105

[13]CurrentPatentAssignee:TAIGENBIOPHARMACEUTICALSHOLDINGSLTD.-US2010/152452,2010,A1Locationinpatent:Page/Pagecolumn9

[14]CurrentPatentAssignee:SAMILABSLIMITED-US2008/26017,2008,A1Locationinpatent:Page/Pagecolumn11

[15]Wu,Wenbin;Li,Zheng;Zhou,Guangbiao;Jiang,Sheng[TetrahedronLetters,2011,vol.52,#19,p.2488-2491]

[16]CurrentPatentAssignee:STELLACHEMIFACORPORATION-EP2319850,2011,A1Locationinpatent:Page/Pagecolumn8

[17]Jörres,Manuel;Schiffers,Ingo;Atodiresei,Iuliana;Bolm,Carsten[OrganicLetters,2012,vol.14,#17,p.4518-4521]

[18]Weber,Frauke;Brune,Stefanie;Börgel,Frederik;Lange,Carsten;Korpis,Katharina;Bednarski,PatrickJ.;Laurini,Erik;Fermeglia,Maurizio;Pricl,Sabrina;Schepmann,Dirk;Wünsch,Bernhard[JournalofMedicinalChemistry,2016,vol.59,#11,p.5505-5519]

[19]Thangavelu,Bharani;Mutthamsetty,Vinay;Wang,Qinzhe;Viola,RonaldE.[BioorganicandMedicinalChemistry,2017,vol.25,#3,p.870-885]

[20]Gruzdev;Levit;Olshevskaya;Krasnov[RussianJournalofOrganicChemistry,2017,vol.53,#5,p.769-776][Zh.Org.Khim.,2017,vol.53,#5,p.756-762,7]

[21]CurrentPatentAssignee:SHAH,DharmeshMahendrabhai;WADER,GuruprasadRamchandra-WO2017/168442,2017,A1Locationinpatent:Page/Pagecolumn8;13

[22]PeiróCadahía,Jorge;Bondebjerg,Jon;Hansen,ChristianA.;Previtali,Viola;Hansen,AndersE.;Andresen,ThomasL.;Clausen,MadsH.[JournalofMedicinalChemistry,2018,vol.61,#8,p.3503-3515]

[23]Ghalehshahi,HajarG.;Balalaie,Saeed;Sohbati,HamidR.;Azizian,Homa;Alavijeh,MohammadS.[ArchivderPharmazie,2019,vol.352,#3]

[24]CurrentPatentAssignee:SICHUANJIAYINGLAITECH-CN111807994,2020,ALocationinpatent:Paragraph0044-0047;0056-0059;0066-0069;0076-0079;0086

[25]Ackermann,Lutz;Berlinck,RobertoG.S.;Bernardi,DarlonI.;Delgado,JoséA.C.;Kaplaneris,Nikolaos;Lima,RafaelyN.;Paixão,MárcioW.[ChemicalCommunications,2021,vol.57,#47,p.5758-5761]

[1]Baltina;Ryzhova;Vasil'eva;Tolstikov;Sakhautdinova;Lazareva;Kondratenko[RussianJournalofBioorganicChemistry,1996,vol.22,#12,p.810-814]

[1]Taylor;Dowling[JournalofOrganicChemistry,1997,vol.62,#6,p.1599-1603]

932-41-2    23150-65-4   
(S)-2-(4-Oxo-4,6-dihydro-thieno2,3-cpyrrol-5-yl)-pentanedioicaciddimethylester 
  191803-92-6 

[1]JournalofOrganicChemistry,1997,vol.62,p.5392-5403

Literature

Title: Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Journal: Nature chemical biology 20090101

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