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23180-57-6,MFCD00869331
Catalog No.:AA00I4GB

23180-57-6 | Paeoniflorin

Pack Size
Purity
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Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
10mg
98%
in stock  
$11.00   $8.00
- +
50mg
98%
in stock  
$27.00   $19.00
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100mg
95%
in stock  
$50.00   $35.00
- +
250mg
95%
in stock  
$96.00   $67.00
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1g
95%
in stock  
$223.00   $156.00
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5g
95%
in stock  
$778.00   $545.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I4GB
Chemical Name:
Paeoniflorin
CAS Number:
23180-57-6
Molecular Formula:
C23H28O11
Molecular Weight:
480.4618
MDL Number:
MFCD00869331
SMILES:
OC[C@H]1O[C@@H](O[C@@]23C[C@@H]4[C@@]3(COC(=O)c3ccccc3)[C@@H]3O[C@@]2(C)C[C@]4(O3)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
849  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
7  
XLogP3:
-1  

Upstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#9,p.4081-4082

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#9,p.4081-4082

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#9,p.4081-4082

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#9,p.4081-4082

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,#9,p.4081-4082

Downstream Synthesis Route

[1]Chemicalandpharmaceuticalbulletin,1987,vol.35,p.3726-3733

[1]Chemicalandpharmaceuticalbulletin,1987,vol.35,p.3726-3733

C59H58O13 
  23180-57-6 

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,p.4081-4082

23180-57-6   
8-O-debenzoylpaeoniflorin 

[1]PlantaMedica,1997,vol.63,p.323-325

[1]BiologicalandPharmaceuticalBulletin,1999,vol.22,p.491-497

Literature

Title: Paeoniflorin reduces neomycin-induced ototoxicity in hair cells by suppression of reactive oxygen species generation and extracellularly regulated kinase signalization.

Journal: Toxicology letters 20180315

Title: Protective Effects of Paeoniflorin Against MPP(+)-induced Neurotoxicity in PC12 Cells.

Journal: Neurochemical research 20160601

Title: Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway.

Journal: Toxicology letters 20130426

Title: Inhibitory effect of paeoniflorin on the inflammatory vicious cycle between adipocytes and macrophages.

Journal: Journal of cellular biochemistry 20120801

Title: Preparative purification of peoniflorin and albiflorin from peony rhizome using macroporous resin and medium-pressure liquid chromatography.

Journal: Journal of separation science 20120801

Title: HPLC-MS/MS method to determine genipin in rat plasma after hydrolysis with sulfatase and its application to a pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20120701

Title: Protective effects of paeoniflorin against corticosterone-induced neurotoxicity in PC12 cells.

Journal: Phytotherapy research : PTR 20120701

Title: UPLC-MS/MS determination of paeoniflorin, naringin, naringenin and glycyrrhetinic acid in rat plasma and its application to a pharmacokinetic study after oral administration of Si-Ni-San decoction.

Journal: Journal of pharmaceutical and biomedical analysis 20120701

Title: Paeoniflorin reduced acute toxicity of aconitine in rats is associated with the pharmacokinetic alteration of aconitine.

Journal: Journal of ethnopharmacology 20120601

Title: BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin.

Journal: Journal of ethnopharmacology 20120507

Title: Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Title: Paeoniflorin inhibits proliferation of fibroblast-like synoviocytes through suppressing G-protein-coupled receptor kinase 2.

Journal: Planta medica 20120501

Title: Protective effects of paeoniflorin against cobalt chloride-induced apoptosis of endothelial cells via HIF-1α pathway.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120401

Title: Expression and function of β-arrestin 2 stimulated by IL-1β in human fibroblast-like synoviocytes and the effect of paeoniflorin.

Journal: International immunopharmacology 20120401

Title: [Influence of different solutions on extracting of active components in Danggui Chishao drug pair].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

Title: [Primary safety evaluation of sulfated paeoniae radix alba].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120401

Title: [Protective effects of paeonol, paeoniflorin and their compatibility on in vitro cultured cardiomyocytes suffering from hypoxia-reoxygenation injury].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120401

Title: Comparative pharmacokinetic study of paeoniflorin and albiflorin after oral administration of Radix Paeoniae Rubra in normal rats and the acute cholestasis hepatitis rats.

Journal: Fitoterapia 20120301

Title: [Screening and identifying of hepatoprotective compounds in paeoniae radix rubra].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120301

Title: Paeoniflorin modulates multidrug resistance of a human gastric cancer cell line via the inhibition of NF-κB activation.

Journal: Molecular medicine reports 20120201

Title: Pharmacokinetic comparisons of albiflorin and paeoniflorin after oral administration of Shaoyao-Gancao-Tang and single herb Paeony decoction to rats.

Journal: Planta medica 20120201

Title: Rapid screening and quantification of sulfonate derivatives in white peony root by UHPLC-MS-MS.

Journal: Analytical and bioanalytical chemistry 20120201

Title: Development and validation of high-performance liquid chromatography/electrospray ionization mass spectrometry for assay of madecassoside in rat plasma and its application to pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20120101

Title: Determination of 5-hydroxymethyl-2-furfural, albiflorin, paeoniflorin, liquiritin, ferulic acid, nodakenin, and glycyrrhizin by HPLC-PDA, and evaluation of the cytotoxicity of Palmul-tang, a traditional Korean herbal medicine.

Journal: Archives of pharmacal research 20120101

Title: Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children.

Journal: PloS one 20120101

Title: Interaction of the main components from the traditional Chinese drug pair Chaihu-Shaoyao based on rat intestinal absorption.

Journal: Molecules (Basel, Switzerland) 20111117

Title: Antinociceptive effect of paeoniflorin via spinal α₂-adrenoceptor activation in diabetic mice.

Journal: European journal of pain (London, England) 20111101

Title: Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1α and regulates EP4 receptor expression.

Journal: Journal of ethnopharmacology 20111011

Title: Modulating Bcl-2 family proteins and caspase-3 in induction of apoptosis by paeoniflorin in human cervical cancer cells.

Journal: Phytotherapy research : PTR 20111001

Title: Paeoniflorin protects against lipopolysaccharide-induced acute lung injury in mice by alleviating inflammatory cell infiltration and microvascular permeability.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20111001

Title: The effects of paeoniflorin monomer of a Chinese herb on cardiac ion channels.

Journal: Chinese medical journal 20111001

Title: Paeoniflorin suppresses the expression of intercellular adhesion molecule-1 (ICAM-1) in endotoxin-treated human monocytic cells.

Journal: British journal of pharmacology 20110901

Title: Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosis through inhibiting alternative activation of macrophages.

Journal: Parasitology 20110901

Title: Peoniflorin suppresses tumor necrosis factor-α induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-κB and ERK pathway.

Journal: Archives of dermatological research 20110701

Title: ASICs mediate the modulatory effect by paeoniflorin on α-synuclein autophagic degradation.

Journal: Brain research 20110617

Title: Protective effects of peoniflorin against hydrogen peroxide-induced oxidative stress in human umbilical vein endothelial cells.

Journal: Canadian journal of physiology and pharmacology 20110601

Title: [Effects of paeoniflorin on expressions of CTGF, PDGF and TNF-alpha in mice with hepatic fibrosis due to Schistosoma japonicum infection].

Journal: Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control 20110601

Title: [Treatment of premenstrual syndrome with Chinese medicine formula, baixiangdan capsule: implications for neuron viability and GABA(A) receptor modulation in rat cortex].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601

Title: Paeoniflorin protects against NMDA-induced neurotoxicity in PC12 cells via Ca2+ antagonism.

Journal: Phytotherapy research : PTR 20110501

Title: [Inhibitory effect of paeoniflorin on the collagen production by fibroblasts through IL-13/STAT6 signaling pathway].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20110430

Title: Comparative pharmacokinetics of paeoniflorin in plasma of vascular dementia and normal rats orally administrated with Danggui-Shaoyao-San or pure paeoniflorin.

Journal: Fitoterapia 20110401

Title: [Pharmacokinetics of Guizhi Fuling capsule in Beagle dogs].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401

Title: Optimization of micellar electrokinetic capillary chromatography method using central composite design for the analysis of components in Yangwei granule.

Journal: Journal of Zhejiang University. Science. B 20110301

Title: [Simultaneous assay of paeoniflorin and albiflorin in Paeoniae Radix Alba by QAMS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

Title: Protective effect of a molecular chaperone inducer, paeoniflorin, on the HCl- and ethanol-triggered gastric mucosal injury.

Journal: Life sciences 20110214

Title: Paeoniflorin improves survival in LPS-challenged mice through the suppression of TNF-α and IL-1β release and augmentation of IL-10 production.

Journal: International immunopharmacology 20110201

Title: Pharmacokinetic properties of albiflorin and paeoniflorin after oral administration of pure compound, Radix Paeoniae alba extract and danggui-shaoyao-san extract to rats.

Journal: Journal of Asian natural products research 20110201

Title: A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality control of guan-xin-er-hao formula.

Journal: Journal of ethnopharmacology 20110127

Title: Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro.

Journal: Molecular vision 20110101

Title: Therapeutic effects of combination of paeoniflorin and albiflorin from Paeonia radix on radiation and chemotherapy-induced myelosuppression in mice and rabbits.

Journal: Asian Pacific journal of cancer prevention : APJCP 20110101

Title: [Relevant study on apoptosis of cervical cancer HeLa cells induced by paeoniflorin].

Journal: Zhonghua yi xue za zhi 20101221

Title: LC-MS/MS determination and pharmacokinetic study of albiflorin and paeoniflorin in rat plasma after oral administration of Radix Paeoniae Alba extract and Tang-Min-Ling-Wan.

Journal: Biomedical chromatography : BMC 20101201

Title: [Study on the best concentration of combination of the effects of the four original constituents of liu-wei di-huang pill on the proliferation and differentiation of rat preadipocyte].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20101201

Title: [Determination of the concentration of paeonflorin of the BYHWD and total glycoside in the plasma of rats by reverse phase high performance liquid chromatography and studies on its pharmacokinetics].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20101101

Title: Protective effects of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via antioxidant mechanisms and Ca(2+) antagonism.

Journal: Cellular and molecular neurobiology 20101001

Title: Ginsenoside Rb1 and paeoniflorin inhibit transient receptor potential vanilloid-1-activated IL-8 and PGE₂ production in a human keratinocyte cell line HaCaT.

Journal: International immunopharmacology 20101001

Title: Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS.

Journal: Fitoterapia 20100901

Title: [Mechanism of protective effect of pretreatment of paeoniflorin on injured cortical neurons with corticosterone].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

Title: Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway.

Journal: Journal of ethnopharmacology 20100819

Title: Sensitive high-performance anion-exchange chromatographic determination of paeoniflorin and albiflorin by pulsed amperometric detection after solid-phase extraction.

Journal: Journal of chromatography. A 20100806

Title: [Simultaneous determination of multicomponent in Xuefuzhuyu granule with different UV-wavelength by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801

Title: Pharmacokinetic properties of paeoniflorin, albiflorin and oxypaeoniflorin after oral gavage of extracts of Radix Paeoniae Rubra and Radix Paeoniae Alba in rats.

Journal: Journal of ethnopharmacology 20100720

Title: The novel anti-hyperglycemic effect of Paeoniae radix via the transcriptional suppression of phosphoenopyruvate carboxykinase (PEPCK).

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100701

Title: Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice.

Journal: Parasitology 20100701

Title: The effects of paeoniflorin on LPS-induced liver inflammatory reactions.

Journal: Archives of pharmacal research 20100601

Title: [Advanced achievements about neuroprotective mechanisms of paeoniflorin].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100601

Title: [Quadratic-orthogonal-rotation-combination design for optimization of ethanol extraction craft from Radix Paeoniae Rubra].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100601

Title: [Pharmacokinetics study on paeoniflorin in radix paeoniae alba extract by LC-MS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100501

Title: Simultaneous determination of four marker components in Yukmijihwang Tang by high performance liquid chromatography/diode array detector.

Journal: Archives of pharmacal research 20100401

Title: [Microbiological transformation of paeoniflorin and albiflorin].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401

Title: [RP-HPLC determination of main chemical components in different parts and different harvest periods of Paeonia lactiflora].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100401

Title: [Prophylactic protective effects of paeoniflorin on corticosterone-induced primary cultures of rat cortical neurons damages].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101

Title: [Paeoniflorin increases beta-defensin expression and attenuates lesion in the colonic mucosa from mice with oxazolone-induced colitis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100101

Title: Paeoniflorin: a monomer from traditional Chinese medical herb ameliorates Schistosoma japonicum egg-induced hepatic fibrosis in mice.

Journal: The Journal of parasitology 20091201

Title: Inhibitory effects of Geijigajakyak-Tang on trinitrobenzene sulfonic acid-induced colitis.

Journal: Journal of ethnopharmacology 20091112

Title: Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A(1) receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway.

Journal: Pharmacology, biochemistry, and behavior 20091101

Title: [Study on the optimal extraction process of chaihushugan powder].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091101

Title: Comparative pharmacokinetic study of paeoniflorin after oral administration of pure paeoniflorin, extract of Cortex Moutan and Shuang-Dan prescription to rats.

Journal: Journal of ethnopharmacology 20090925

Title: Paeoniflorin protects RAW 264.7 macrophages from LPS-induced cytotoxicity and genotoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090901

Title: [Purification of total paeony glycoside by macroporous resin with double indices of albiflorin and paeoniflorin].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090801

Title: Effects of peony glycosides on mice exposed to chronic unpredictable stress: further evidence for antidepressant-like activity.

Journal: Journal of ethnopharmacology 20090715

Title: Paeoniflorin inhibits systemic inflammation and improves survival in experimental sepsis.

Journal: Basic & clinical pharmacology & toxicology 20090701

Title: [Influence of glycyrrhizin on paeoniflorin pharmacokinetic fate in unrestrained conscious rats by intravenous administration].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090701

Title: [Anti-inflammatory effects and quantitative study of the combinations of active ingredients of Painong powder in mice].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090601

Title: Detection of albiflorin and paeoniflorin in Paeoniae radix by reversed-phase high-performance liquid chromatography with pulsed amperometric detection.

Journal: Journal of chromatography. A 20090522

Title: Peoniflorin attentuates Abeta((1-42))-mediated neurotoxicity by regulating calcium homeostasis and ameliorating oxidative stress in hippocampus of rats.

Journal: Journal of the neurological sciences 20090515

Title: [Absorption of extractive Radix Paeoniae Alba in rat everted gut sacs and its interaction with P-glycoprotein].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

Title: [Effects of Mn, Fe, Zn and Cu on growth and paeoniflorin content of Paeonia lactiflora].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

Title: Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice.

Journal: Life sciences 20090313

Title: Chemical profiling of Radix Paeoniae evaluated by ultra-performance liquid chromatography/photo-diode-array/quadrupole time-of-flight mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20090220

Title: Effect of Guanxin No.2 decoction on gene expression in different areas of the myocardial infarcted heart of rats using microarray technology.

Journal: The Journal of pharmacy and pharmacology 20090201

Title: Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection.

Journal: Phytochemical analysis : PCA 20090101

Title: LC determination of albiflorin and paeoniflorin in Bai Shao (Paeonia lactiflora) as a raw herb and dried aqueous extract.

Journal: Journal of AOAC International 20090101

Title: Simultaneous determination of 12 chemical constituents in the traditional Chinese Medicinal Prescription Xiao-Yao-San-Jia-Wei by HPLC coupled with photodiode array detection.

Journal: Journal of pharmaceutical and biomedical analysis 20081215

Title: Screening and analyzing the potential bioactive components from Shaofu Zhuyu decoction, using human umbilical vein endothelial cell extraction and high-performance liquid chromatography coupled with mass spectrometry.

Journal: Biomedical chromatography : BMC 20081201

Title: An approach based on HPLC-fingerprint and chemometrics to quality consistency evaluation of Liuwei Dihuang Pills produced by different manufacturers.

Journal: Journal of pharmaceutical and biomedical analysis 20081201

Title: Paeoniflorin suppress NF-kappaB activation through modulation of I kappaB alpha and enhances 5-fluorouracil-induced apoptosis in human gastric carcinoma cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081101

Title: [Simultaneous determination and pharmacokinetic studies of ferulic acid and paeoniflorin in human serum by high performance liquid chromatography after oral administration of Modified Xiao-yao Decoction].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20081101

Title: [Study on preparation and determination of Liaojin plastics].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081101

Title: [Determination of paeoniflorin in rat plasma by HPLC-MS/MS and its pharmacokinetics].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

Title: [Progressive studies of paeoniflorin].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

Title: [Studies on content determination and fingerprint of active constituents in different parts of cortex moutan].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

Title: Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast-like synoviocytes of collagen induced arthritic rats.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080801

Title: The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats.

Journal: The journal of pain : official journal of the American Pain Society 20080601

Title: [Study of using shattering extraction with solvent to extract ingredient of three kinds of traditional Chinese medicine].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601

Title: Comparative pharmacokinetic study of paeoniflorin after oral administration of decoction of Radix Paeoniae Rubra and Radix Paeoniae Alba in rats.

Journal: Journal of ethnopharmacology 20080522

Title: Monoterpene glycosides from Paeonia hybrida.

Journal: Phytochemistry 20080501

Title: Inflammation in Parkinson's disease: an update.

Journal: Current opinion in investigational drugs (London, England : 2000) 20080501

Title: A genome-wide microarray analysis reveals anti-inflammatory target genes of paeonol in macrophages.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080401

Title: Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol.

Journal: Archives of pharmacal research 20080401

Title: [Comparison of the content of effective components between tree peony wild species and main cultivars].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080301

Title: [Effect of paeoniflorin on hepatic immunopathogenesis in mice with Schistosoma japonicum infection].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20080227

Title: Phenolic and other constituents of fresh water fern Salvinia molesta.

Journal: Phytochemistry 20080201

Title: New monoterpene glycosides from Paeonia lactiflora.

Journal: Fitoterapia 20080201

Title: [Dynamic change of paeoniflorin content in root of Paeonia lactiflora growing at Duolun County, Inner Mongolia].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080201

Title: Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats.

Journal: Planta medica 20080101

Title: [Comparison of ferulic acid and paeoniflorin between traditional slice decoction and dispensing granule decoction of Siwu Tang].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101

Title: Antinociceptive effects of systemic paeoniflorin on bee venom-induced various 'phenotypes' of nociception and hypersensitivity.

Journal: Pharmacology, biochemistry, and behavior 20071201

Title: Protective effect of paeoniflorin against optic nerve crush.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071201

Title: [Effects of paeoniflorin on pathological changes in global brain ischemia model rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

Title: [The quality control of carbonized cortex moutan].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201

Title: Simultaneous analysis of glycyrrhizin, paeoniflorin, quercetin, ferulic acid, liquiritin, formononetin, benzoic acid and isoliquiritigenin in the Chinese proprietary medicine Xiao Yao Wan by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis 20071105

Title: [Effects of paeoniflorin on the level of antibodies and cAMP produced by splenocytes in rats with adjuvant arthritis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071101

Title: Paeoniflorin inhibits TGF-beta1-mediated collagen production by Schistosoma japonicum soluble egg antigen in vitro.

Journal: Parasitology 20071001

Title: A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells.

Journal: Archives of pharmacal research 20071001

Title: Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the determination of paeoniflorin in rat brain and its application to pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915

Title: Orthogonal array design for optimizing extraction efficiency of active constituents from Jakyak-Gamcho Decoction, the complex formula of herbal medicines, Paeoniae Radix and Glycyrrhizae Radix.

Journal: Journal of ethnopharmacology 20070905

Title: Simultaneous determination of four bioactive constituents in Liuwei Dihuang Pills by micellar electrokinetic chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20070903

Title: Identification of genes responsive to paeoniflorin, a heat shock protein-inducing compound, in human leukemia U937 cells.

Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20070901

Title: [Study on adscription of plasma effective constituents of rat after administrated with Paeonia lacliflora and Glycyrrhiza uralensis compound].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801

Title: [Dynamic analysis of major active ingredients of Cortex Moutan cultivated in Dianjiang county of Chongqing].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

Title: Behavioral recovery following sub-chronic paeoniflorin administration in the striatal 6-OHDA lesion rodent model of Parkinson's disease.

Journal: Journal of ethnopharmacology 20070613

Title: [Separation and refine of Xiaoyao Pill by macroporous adsorption resin].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

Title: Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing beta 2-adrenergic receptor desensitization in rats with adjuvant arthritis.

Journal: International immunopharmacology 20070501

Title: Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070501

Title: Analysis of sodium adduct paeoniflorin, albiflorin and their derivatives by (+)ESI-MSn, DFT calculations and computer-aided mass spectrometry analysis program.

Journal: Journal of mass spectrometry : JMS 20070301

Title: Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases.

Journal: The international journal of biochemistry & cell biology 20070101

Title: [Simultaneous analysis of six effective components in the anti-Alzheimer's disease effective component group of Xiao-Xu-Ming Decoction].

Journal: Se pu = Chinese journal of chromatography 20070101

Title: [HPLC fingerprinting of radix paeoniae alba].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070101

Title: Kinetic distribution of paeoniflorin in cortex of normal and cerebral ischemia-reperfusion rats after intravenous administration of Paeoniae Radix extract.

Journal: Biomedical chromatography : BMC 20061201

Title: Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine.

Journal: Pharmaceutical research 20061201

Title: Improvement of the agitation granulation method to prepare granules containing a high content of a very hygroscopic drug.

Journal: The Journal of pharmacy and pharmacology 20061101

Title: Involvement of multitargets in paeoniflorin-induced preconditioning.

Journal: The Journal of pharmacology and experimental therapeutics 20061001

Title: [Simultaneous determination of three active constituents in cortex moutan by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001

Title: Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice.

Journal: The Journal of pharmacy and pharmacology 20060901

Title: [Study on influence of processing methods on chemical constituents in Radix Paeoniae Alba].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060901

Title: [Study on purification of Radix Paeoniae Alba by HPD100 macroporous resin].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060901

Title: Potentiation of adenosine A1 receptor agonist CPA-induced antinociception by paeoniflorin in mice.

Journal: Biological & pharmaceutical bulletin 20060801

Title: Effects of four Si-Wu-Tang's constituents and their combination on irradiated mice.

Journal: Biological & pharmaceutical bulletin 20060701

Title: [Determination of salvianolic acid B and paeoniflorin in Shuangdan granules by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060701

Title: [Study on quality control of Paeonia lactiflora].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060701

Title: Design and synthesis of a biotin-tagged photoaffinity probe of paeoniflorin.

Journal: Bioorganic & medicinal chemistry letters 20060615

Title: Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor.

Journal: British journal of pharmacology 20060601

Title: [Experimental study on processing of Paeonia lactiflora].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060601

Title: Paeoniflorin attenuates chronic cerebral hypoperfusion-induced learning dysfunction and brain damage in rats.

Journal: Brain research 20060517

Title: [Effects of paeoniflorin on cerebral energy metabolism, nitric oxide and nitric oxide synthase after cerebral ischemia in mongoliagerbils].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060501

Title: Studies of the pharmacokinetics of paeoniflorin in two Jing-Zhi-Guan-Xin formulations after oral administration to beagle dogs.

Journal: Journal of pharmaceutical and biomedical analysis 20060411

Title: Design and evaluation of jingzhiguanxin monolithic osmotic pump tablet.

Journal: Chemical & pharmaceutical bulletin 20060401

Title: Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: modulation of tumour necrosis factor-alpha and interleukin-6 MRNA.

Journal: Clinical and experimental pharmacology & physiology 20060401

Title: Determination of paeonol and paeoniflorin in Chinese medicine Cortex Moutan and 'Shuangdan' granule by micellar electrokinetic capillary chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20060318

Title: The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.

Journal: Journal of ethnopharmacology 20060220

Title: Determination of paeoniflorin in rat plasma by a liquid chromatography-tandem mass spectrometry method coupled with solid-phase extraction.

Journal: Biomedical chromatography : BMC 20060201

Title: Construction and expression of a single chain Fv fragment against pharmacologically active paeoniflorin in Escherichia coli, and its potential use in an enzyme-linked immunosorbent assay.

Journal: Planta medica 20060201

Title: Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin.

Journal: Journal of cosmetic science 20060101

Title: RP-HPLC detection of a sulphiting-induced artefact from paeoniflorin in dried roots of Paeonia lactiflora.

Journal: Phytochemical analysis : PCA 20060101

Title: Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats.

Journal: Life sciences 20051212

Title: Pharmacokinetic interaction of paeoniflorin and sinomenine: pharmacokinetic parameters and tissue distribution characteristics in rats and protein binding ability in vitro.

Journal: Journal of pharmacological sciences 20051201

Title: Inhibitory action of L-type Ca2+ current by paeoniflorin, a major constituent of peony root, in NG108-15 neuronal cells.

Journal: European journal of pharmacology 20051031

Title: Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists.

Journal: British journal of pharmacology 20051001

Title: [Study on enhancing bioavailability of paeoniflorin by combined use with Chinese herbs for inner-warming].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050901

Title: [The simultaneous determination of laetrile, paeoniflorin and paeonol in Jingzhi Guizhi Fuling capsule by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050801

Title: Influence of co-administrated sinomenine on pharmacokinetic fate of paeoniflorin in unrestrained conscious rats.

Journal: Journal of ethnopharmacology 20050513

Title: [Study on quality control of effective fraction in qixue bingzhi decoction].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050401

Title: Rapid determination of paeoniflorin and three sugars in Radix Paeoniae Alba by capillary electrophoresis.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050301

Title: Simultaneous determination of albiflorin and paeoniflorin in rat urine by solid-phase extraction and high-performance liquid chromatography following oral administration of Si-Wu decoction.

Journal: Biomedical chromatography : BMC 20041201

Title: Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats.

Journal: Journal of ethnopharmacology 20041001

Title: Paeoniflorin, a novel heat shock protein-inducing compound.

Journal: Cell stress & chaperones 20041001

Title: Paeoniflorin induces apoptosis of lymphocytes through a redox-linked mechanism.

Journal: Journal of cellular biochemistry 20040901

Title: [Studies on chemical constituents in root of Paeonia sinjiangensis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040801

Title: [Quality evaluation of prepared slices of Paeonia lactiflon--determination of paeoniflorin by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040801

Title: Solid-phase extraction-liquid chromatographic method for the determination and pharmacokinetic studies of albiflorin and paeoniflorin in rat serum after oral administration of Si-Wu decoction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040705

Title: Purification of paeoniflorin from Paeonia lactiflora Pall. by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20040625

Title: [Preliminary study on hematopoietic constituents of si-wu-tang].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040601

Title: Determination of paeoniflorin in rat hippocampus by high-performance liquid chromatography after intravenous administration of Paeoniae Radix extract.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040405

Title: [Investigation of constituents in siwu tang fractions by chromatographic and ESI-MS methods].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040401

Title: Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora.

Journal: Fitoterapia 20040101

Title: Blockade of paeoniflorin on sodium current in mouse hippocampal CA1 neurons.

Journal: Acta pharmacologica Sinica 20031201

Title: A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats.

Journal: Planta medica 20031201

Title: Restorative effect of repetitive administration of Shaoyao-Gancao-tang on bioavailability of paeoniflorin reduced by antibacterial synthetic drugs treatment in rats.

Journal: Biological & pharmaceutical bulletin 20031101

Title: SPE-HPLC method for the determination and pharmacokinetic studies on paeoniflorin in rat serum after oral administration of traditional Chinese medicinal preparation Guan-Xin-Er-Hao decoction.

Journal: Journal of pharmaceutical and biomedical analysis 20031015

Title: [Determination of glycosides in traditional Chinese medicine liu-wei di-huang by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030801

Title: A quantitative ELISA using monoclonal antibody to survey paeoniflorin and albiflorin in crude drugs and traditional Chinese herbal medicines.

Journal: Biological & pharmaceutical bulletin 20030601

Title: [The contents of paeoniflorin in different combination jingzhixuefuzhuyu].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030601

Title: Stimulatory effect of paeoniflorin on adenosine release to increase the glucose uptake into white adipocytes of Wistar rat.

Journal: Planta medica 20030401

Title: Influence of co-administered antibiotics on the pharmacokinetic fate in rats of paeoniflorin and its active metabolite paeonimetabolin-I from Shaoyao-Gancao-tang.

Journal: The Journal of pharmacy and pharmacology 20030301

Title: [Study on pharmacokinetics of ferulic acid and paeoniflorin in Angelic-Paeonia root powder].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030301

Title: [Paeoniflorin Reference Standard (Control 021) of National Institute of Health Sciences].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20030101

Title: Development of a simple HPLC method for determination of paeoniflorin-metabolizing activity of intestinal bacteria in rat feces.

Journal: Chemical & pharmaceutical bulletin 20020901

Title: [Research on the quality of original plants and material medicine of Cortex Paeoniae].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020901

Title: Stimulatory effect of paeoniflorin on the release of noradrenaline from ileal synaptosomes of guinea-pig in-vitro.

Journal: The Journal of pharmacy and pharmacology 20020501

Title: Effects of veratrine and paeoniflorin on isolated mouse vas deferens.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20020501

Title: Pharmacokinetics of paeoniflorin after oral administration of Shao-yao Gan-chao Tang in mice.

Journal: Japanese journal of pharmacology 20020301

Title: [Paeoniflorin Reference Standard (Control 011) of National Institute of Health Sciences].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20020101

Title: Anti-thrombosis effect of paeoniflorin: evaluated in a photochemical reaction thrombosis model in vivo.

Journal: Planta medica 20011101

Title: New paeonilactone-A adducts formed by anaerobic incubation of paeoniflorin with Lactobacillus brevis in the presence of arylthiols.

Journal: Chemical & pharmaceutical bulletin 20010701

Title: [Isolation and elucidation of chemical constituents of shandanshaoyao decoction (II)].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010701

Title: Effects of paeoniflorin on the formalin-induced nociceptive behaviour in mice.

Journal: Journal of ethnopharmacology 20010501

Title: Ameliorative effects of paeoniflorin, a major constituent of peony root, on adenosine A1 receptor-mediated impairment of passive avoidance performance and long-term potentiation in the hippocampus.

Journal: Biological & pharmaceutical bulletin 20010501

Title: Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats.

Journal: Clinical and experimental pharmacology & physiology 19991001

Title: Effects of paeoniflorin derivatives on scopolamine-induced amnesia using a passive avoidance task in mice; structure-activity relationship.

Journal: Biological & pharmaceutical bulletin 19981101

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Tags:23180-57-6 Molecular Formula|23180-57-6 MDL|23180-57-6 SMILES|23180-57-6 Paeoniflorin