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23312-56-3,MFCD04112608
Catalog No.:AA00JKGC

23312-56-3 | Spectinomycin sulfate

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1g
93 - 102% (Assay, anhydrous basis)
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00JKGC
Chemical Name:
Spectinomycin sulfate
CAS Number:
23312-56-3
Molecular Formula:
C14H26N2O11S
Molecular Weight:
430.4280
MDL Number:
MFCD04112608
SMILES:
CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O.OS(=O)(=O)O
NSC Number:
100859
Properties
Computed Properties
 
Complexity:
559  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
2  

Literature

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Journal: Nature medicine 20140201

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Surveillance of gonococcal antimicrobial susceptibility resulting in early detection of emerging resistance.

Journal: The Journal of antimicrobial chemotherapy 20120601

Title: A cloning vector for creation of Escherichia coli lacZ translational fusions and generation of linear template for chromosomal integration.

Journal: Plasmid 20120501

Title: Efficacy and safety of ceftriaxone for uncomplicated gonorrhoea: a meta-analysis of randomized controlled trials.

Journal: International journal of STD & AIDS 20120201

Title: Physiologic consequences of glucose transport and phosphoenolpyruvate node modifications in Bacillus subtilis 168.

Journal: Journal of molecular microbiology and biotechnology 20120101

Title: Determination of water content by capillary gas chromatography coupled with thermal conductivity detection.

Journal: Pharmeuropa bio & scientific notes 20111101

Title: 2-Oxoglycosyl ('ulosyl') and 2-oximinoglycosyl bromides: versatile donors for the expedient assembly of oligosaccharides with β-D-mannose, β-L-rhamnose, N-acetyl-β-D-mannosamine, and N-acetyl-β-D-mannosaminuronic acid units.

Journal: Chemical reviews 20110914

Title: Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.

Journal: Antimicrobial agents and chemotherapy 20110801

Title: Resistance to azithromycin of Neisseria gonorrhoeae isolates from 2 cities in China.

Journal: Sexually transmitted diseases 20110801

Title: [Detection and the antibiotic susceptibility analysis of mycoplasma and chlamydia in urogenital tract infections of 327 cases patients with tubal infertility].

Journal: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20110601

Title: In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110501

Title: The Neisseria gonorrhoeae photolyase orthologue phrB is required for proper DNA supercoiling but does not function in photo-reactivation.

Journal: Molecular microbiology 20110201

Title: A real-time PCR antibiogram for drug-resistant sepsis.

Journal: PloS one 20110101

Title: Characterization of two novel gene cassettes, dfrA27 and aadA16, in a non-O1, non-O139 Vibrio cholerae isolate from China.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100801

Title: The Russian gonococcal antimicrobial susceptibility programme (RU-GASP)--national resistance prevalence in 2007 and 2008, and trends during 2005-2008.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20100408

Title: Transformation of Anaplasma marginale.

Journal: Veterinary parasitology 20100210

Title: Influence of aminoglycoside antibiotics on the thermal behaviour and structural features of DPPE-DPPG model membranes.

Journal: Colloids and surfaces. B, Biointerfaces 20100101

Title: Mismatch correction modulates mutation frequency and pilus phase and antigenic variation in Neisseria gonorrhoeae.

Journal: Journal of bacteriology 20100101

Title: Neisseria gonorrhoeae antibiotic resistance in Paris, 2005 to 2007: implications for treatment guidelines.

Journal: Acta dermato-venereologica 20090101

Title: Clinical efficacy of the various drugs used in the treatment of gonorrhoeae.

Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20090101

Title: Antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in 2004-2006 in Bangui, Central African Republic; Yaoundé, Cameroon; Antananarivo, Madagascar; and Ho Chi Minh Ville and Nha Trang, Vietnam.

Journal: Sexually transmitted diseases 20081101

Title: National surveillance of antimicrobial susceptibility in Neisseria gonorrhoeae in 2005-2006 and recommendations of first-line antimicrobial drugs for gonorrhoea treatment in Russia.

Journal: Sexually transmitted infections 20080801

Title: Single-dose treatment of male patients with gonococcal urethritis using 2g spectinomycin: microbiological and clinical evaluations.

Journal: International journal of antimicrobial agents 20080701

Title: In vitro mutagenesis of Bacillus subtilis by using a modified Tn7 transposon with an outward-facing inducible promoter.

Journal: Applied and environmental microbiology 20080601

Title: Probing RNA-antibiotic interactions: a FTIR study.

Journal: Molecular biology reports 20080301

Title: Characterization of antimicrobial susceptibility and virulence genes of Salmonella serovars collected at a commercial turkey processing plant.

Journal: Journal of applied microbiology 20080101

Title: Antibiotic-resistant gonococci - past, present and future.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20071101

Title: Gonococcal resistance: evolving from penicillin, tetracycline to the quinolones in South Africa -- implications for treatment guidelines.

Journal: International journal of STD & AIDS 20071001

Title: [Acute urethritis caused by Neisseria meningitidis and Chlamydia trachomatis].

Journal: Hinyokika kiyo. Acta urologica Japonica 20071001

Title: Effects of tiamulin, neomycin, tetracycline, fluorophenicol, penicillin G, Linco-Spectin, erythromycin and oxytetracycline on controlling bacterial contaminations of the river buffalo (Buballus bubalis) semen.

Journal: Pakistan journal of biological sciences : PJBS 20070915

Title: Antimicrobial resistance for Neisseria gonorrhoeae in the United States, 1988 to 2003: the spread of fluoroquinolone resistance.

Journal: Annals of internal medicine 20070717

Title: Contribution of the Rv2333c efflux pump (the Stp protein) from Mycobacterium tuberculosis to intrinsic antibiotic resistance in Mycobacterium bovis BCG.

Journal: The Journal of antimicrobial chemotherapy 20070301

Title: [The correlation between phenotypes and genotypes of macrolides, lincosamides and streptogramins B resistance in Staphylococcus aureus].

Journal: Medycyna doswiadczalna i mikrobiologia 20070101

Title: Susceptibility of bacterial pathogens against lincomycin/spectinomycin (1/2), penicillin G/neomycin (1/1), and penicillin G/dihydrostreptomycin (1/1) as determined in the BfT-GermVet monitoring program 2004-2006.

Journal: Berliner und Munchener tierarztliche Wochenschrift 20070101

Title: [Antimicrobial resistance in Neisseria gonorrheae in North-East Romania].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101

Title: A novel single amino acid change in small subunit ribosomal protein S5 has profound effects on translational fidelity.

Journal: RNA (New York, N.Y.) 20061201

Title: Determination of spectinomycin hydrochloride and its related substances by HPLC-ELSD and HPLC-MSn.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060413

Title: Antibiotic susceptibility patterns of Neisseria gonorrhoeae isolates in Port Elizabeth.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20060301

Title: Activity of translation system and abundance of tmRNA during development of Streptomyces aureofaciens producing tetracycline.

Journal: Folia microbiologica 20060101

Title: A pilot study on antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Nepal.

Journal: Sexually transmitted diseases 20051001

Title: First case of spectinomycin resistant Neisseria gonorrhoeae isolate in New Delhi, India.

Journal: Sexually transmitted infections 20050401

Title: Rapid isolation of Brachyspira hyodysenteriae and Brachyspira pilosicoli from pigs.

Journal: Veterinary microbiology 20050225

Title: [Clinical study of male urethritis in Oogaki Municipal Hospital].

Journal: Hinyokika kiyo. Acta urologica Japonica 20050101

Title: Human safety and genetically modified plants: a review of antibiotic resistance markers and future transformation selection technologies.

Journal: Journal of applied microbiology 20050101

Title: Detection of a novel aph(2') allele (aph[2']-Ie) conferring high-level gentamicin resistance and a spectinomycin resistance gene ant(9)-Ia (aad 9) in clinical isolates of enterococci.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20050101

Title: Gonorrhea treatment guidelines in Canada: 2004 update.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20041123

Title: Antibiotic multiresistance plasmid pRSB101 isolated from a wastewater treatment plant is related to plasmids residing in phytopathogenic bacteria and carries eight different resistance determinants including a multidrug transport system.

Journal: Microbiology (Reading, England) 20041101

Title: Hypermutable Haemophilus influenzae with mutations in mutS are found in cystic fibrosis sputum.

Journal: Microbiology (Reading, England) 20040901

Title: Generation of fertile transplastomic soybean.

Journal: Plant molecular biology 20040701

Title: A plasmid-encoded class 1 integron carrying sat, a putative phosphoserine phosphatase gene and aadA2 from enterotoxigenic Escherichia coli O159 isolated in Japan.

Journal: FEMS microbiology letters 20040615

Title: Development of a fluorescent latex immunoassay for detection of a spectinomycin antibiotic.

Journal: Journal of agricultural and food chemistry 20040602

Title: Antimicrobial susceptibility among Neisseria gonorrhoeae in New Zealand in 2002.

Journal: The New Zealand medical journal 20040402

Title: In vitro activities of spectinomycin and comparator agents against Pasteurella multocida and Mannheimia haemolytica from respiratory tract infections of cattle.

Journal: The Journal of antimicrobial chemotherapy 20040201

Title: Characterization of antimicrobial resistant Salmonella Kinshasa from dairy calves in Texas.

Journal: Letters in applied microbiology 20040101

Title: [Interaction of aminoglycosides and the other antibiotic on selected bacterial strains].

Journal: Medycyna doswiadczalna i mikrobiologia 20040101

Title: Frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae in Tokyo in 2002.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201

Title: [Resistance of Neisseria gonorrhoeae to 4 antibiotics: an analysis of the situation in Guangzhou in 2002].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20031001

Title: Antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in Guangzhou, China, 1996-2001.

Journal: Sexually transmitted infections 20031001

Title: Persistence of unselected transgenic DNA during a plastid transformation and segregation approach to herbicide resistance.

Journal: Plant physiology 20030901

Title: In vitro susceptibilities of field isolates of Mycoplasma agalactiae to oxytetracycline, tylosin, enrofloxacin, spiramycin and lincomycin-spectinomycin.

Journal: Research in veterinary science 20030801

Title: High percentages of resistance to tetracycline and penicillin and reduced susceptibility to azithromycin characterize the majority of strain types of Neisseria gonorrhoeae isolates in Cuba, 1995-1998.

Journal: Sexually transmitted diseases 20030501

Title: [Residue analysis of spectinomycin in tissues of chicken and swine by HPLC].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20030401

Title: [Antibiotic susceptibility of Neisseria gonorrhoeae epidemic strains in Changsha].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030227

Title: Isolation of spectinomycin resistance mutations in the 16S rRNA of Salmonella enterica serovar Typhimurium and expression in Escherichia coli and Salmonella.

Journal: Current microbiology 20021201

Title: Screening of Salmonella isolates from a turkey production facility for antibiotic resistance.

Journal: Poultry science 20021001

Title: The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS6100.

Journal: Plasmid 20020901

Title: Analysis of a formulation containing lincomycin and spectinomycin by liquid chromatography with pulsed electrochemical detection.

Journal: Journal of pharmaceutical and biomedical analysis 20020620

Title: [In vitro resistance acquisition in Mycoplasma gallisepticum against ofloxacin, tylosin and spectinomycin].

Journal: The Japanese journal of antibiotics 20020601

Title: Analysis of spectinomycin by liquid chromatography with pulsed electrochemical detection.

Journal: Journal of chromatography. A 20020412

Title: The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans.

Journal: Molecular microbiology 20020201

Title: Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step.

Journal: Nature genetics 20020101

Title: Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2001. World Health Organization.

Journal: Communicable diseases intelligence quarterly report 20020101

Title: Non-penicillinase producing Neisseria gonnorhoeae: are they still in existence in Ibadan, Nigeria?

Journal: African journal of medicine and medical sciences 20011201

Title: Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent.

Journal: Sexually transmitted diseases 20010901

Title: Antibiotic resistant N. gonorrhoeae in Trinidad and Tobago.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20010901

Title: Comparison of Neisseria gonorrhoeae isolates from the genital tract and pharynx of two gonorrhea patients.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010901

Title: The effect of organic acids on the control of porcine post-weaning diarrhoea.

Journal: Research in veterinary science 20010601

Title: Intestinal spirochete infections of chickens: a review of disease associations, epidemiology and control.

Journal: Animal health research reviews 20010601

Title: Emergence of cephem- and aztreonam-high-resistant Neisseria gonorrhoeae that does not produce beta-lactamase.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010301

Title: [Decreased incidence of postgonococcal urethritis following minocycline treatment compared to penicillin/spectinomycin].

Journal: Zeitschrift fur Hautkrankheiten 19860601

Title: Spectinomycin and cholestatic jaundice.

Journal: Annals of internal medicine 19851101

Title: One gram of cefoxitin cures uncomplicated gonococcal urethritis caused by penicillinase-producing Neisseria gonorrhoeae (PPNG).

Journal: Sexually transmitted diseases 19830101

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Tags:23312-56-3 Molecular Formula|23312-56-3 MDL|23312-56-3 SMILES|23312-56-3 Spectinomycin sulfate