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233275-76-8,MFCD22683821
Catalog No.:AA00BF9E

233275-76-8 | MK 0343

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
95%
in stock  
$668.00   $468.00
- +
250mg
95%
in stock  
$1,827.00   $1,279.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00BF9E
Chemical Name:
MK 0343
CAS Number:
233275-76-8
Molecular Formula:
C19H17F2N7O
Molecular Weight:
397.3814
MDL Number:
MFCD22683821
SMILES:
Fc1cccc(c1c1nnc2n1nc(OCc1ncnn1C)c(c2)C1CCC1)F
Properties
Computed Properties
 
Complexity:
561  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3  

Literature

Title: MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans.

Journal: Journal of psychopharmacology (Oxford, England) 20110301

Title: GABAA receptor alpha2/alpha3 subtype-selective modulators as potential nonsedating anxiolytics.

Journal: Current topics in behavioral neurosciences 20100101

Title: Atack JR, et al. MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans. J Psychopharmacol. 2011 Mar;25(3):314-28.

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SDS
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Tags:233275-76-8 Molecular Formula|233275-76-8 MDL|233275-76-8 SMILES|233275-76-8 MK 0343
Catalog No.: AA00BF9E
233275-76-8,MFCD22683821
233275-76-8 | MK 0343
Pack Size： 50mg
Purity： 95%
in stock
$668.00 $468.00
Pack Size： 250mg
Purity： 95%
in stock
$1,827.00 $1,279.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00BF9E
Chemical Name: MK 0343
CAS Number: 233275-76-8
Molecular Formula: C19H17F2N7O
Molecular Weight: 397.3814
MDL Number: MFCD22683821
SMILES: Fc1cccc(c1c1nnc2n1nc(OCc1ncnn1C)c(c2)C1CCC1)F
Properties
Complexity: 561  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 29  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3  
Literature fold

Title: MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans.

Journal: Journal of psychopharmacology (Oxford, England)20110301

Title: GABAA receptor alpha2/alpha3 subtype-selective modulators as potential nonsedating anxiolytics.

Journal: Current topics in behavioral neurosciences20100101

Title: Atack JR, et al. MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans. J Psychopharmacol. 2011 Mar;25(3):314-28.

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