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23496-41-5,MFCD02259442
Catalog No.:AA002NBP

23496-41-5 | Peimine

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5mg
≥98%
in stock  
$70.00   $49.00
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10mg
≥98%
in stock  
$118.00   $82.00
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25mg
≥98%
in stock  
$223.00   $156.00
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50mg
≥98%
in stock  
$409.00   $286.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002NBP
Chemical Name:
Peimine
CAS Number:
23496-41-5
Molecular Formula:
C27H45NO3
Molecular Weight:
431.6511
MDL Number:
MFCD02259442
SMILES:
O[C@H]1CC[C@]2([C@H](C1)[C@@H](O)C[C@@H]1[C@@H]2C[C@@H]2[C@H]1CC[C@H]1[C@H]2CN2C[C@@H](C)CC[C@H]2[C@@]1(C)O)C
Properties
Computed Properties
 
Complexity:
715  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
13  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
XLogP3:
4.1  

Literature

Title: Determination of peimine and peiminine in Bulbus Fritillariae Thunbergii by capillary electrophoresis by indirect UV detection using N-(1-naphthyl)ethylenediamine dihydrochloride as probe.

Journal: Electrophoresis 20120701

Title: Antinociceptive efficacy of verticinone in murine models of inflammatory pain and paclitaxel induced neuropathic pain.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Simultaneous determination of peimine and peiminine in rat plasma by LC-ESI-MS employing solid-phase extraction.

Journal: Biomedical chromatography : BMC 20100801

Title: Development and validation of a liquid chromatography-mass spectrometry method for the determination of verticinone in rat plasma and its application to pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100801

Title: [Simultaneous determination of peimine and peiminine in rat plasma by LC-MS/MS and its application in the pharmacokinetic study].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100701

Title: Sensitive determination of verticine and verticinone in Bulbus Fritillariae by ionic liquid assisted capillary electrophoresis-electrochemiluminescence system.

Journal: Talanta 20091215

Title: Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral grooves.

Journal: Biochimie 20090701

Title: Structural analysis and antitussive evaluation of five novel esters of verticinone and bile acids.

Journal: Steroids 20090101

Title: Cytotoxic alkaloids from the bulbs of Fritillaria hupehensis.

Journal: Chemistry & biodiversity 20080201

Title: Synthesis and antitussive evaluation of verticinone-cholic acid salt, a novel and potential cough therapeutic agent.

Journal: Acta pharmacologica Sinica 20071001

Title: [Simultaneous determination of peimine, peiminine and zhebeinine in Fritillaria thunbergii from different habitat by HPLC-ELSD].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

Title: Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).

Journal: European journal of pharmacology 20070322

Title: [Preparation and antitussive, expectorant and antiasthmatic activities of verticinone-bile acids salts].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070301

Title: Differentiation-inducing effects of verticinone, an isosteroidal alkaloid isolated from the bulbus of Fritillaria ussuriensis, on human promyelocytic leukemia HL-60 cells.

Journal: Biological & pharmaceutical bulletin 20021101

Title: Yi PF, et al. Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 macrophages. Immunopharmacol Immunotoxicol. 2013 Oct;35(5):567-72.

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