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2361-27-5,MFCD00005435
Catalog No.:AA003HVH

2361-27-5 | 2-Thiophenecarboxylic acid hydrazide

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1g
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$15.00   $11.00
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5g
98%
in stock  
$19.00   $14.00
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10g
98%
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$35.00   $25.00
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25g
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100g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003HVH
Chemical Name:
2-Thiophenecarboxylic acid hydrazide
CAS Number:
2361-27-5
Molecular Formula:
C5H6N2OS
Molecular Weight:
142.1789
MDL Number:
MFCD00005435
SMILES:
NNC(=O)c1cccs1
Properties
Properties
 
Form:
Solid  
MP:
136-139 °C(lit.)  
Refractive Index:
1.6430 (estimate)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
118  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
0.6  

Downstream Synthesis Route
2361-27-5    120-57-0   
(E)-N'-(benzod1,3dioxol-5-ylmethylene)thiophene-2-carbohydrazide 

[1]Leal,CarlaMoreira;Pereira,SharleneLopes;Leal,DaniellaMoreira;Fraga,CarlosAlbertoM.;Barreiro,EliezerJesus;Sudo,RobertoTakashi;Zapata-Sudo,Gisele;Kuemmerle,ArthurEugen;DeSant'Anna,CarlosM.R.;Tesch,Roberta[EuropeanJournalofMedicinalChemistry,2012,vol.55,p.49-57,9]

[2]Buu-Hoietal.[JournaloftheChemicalSociety,1953,p.547]

2361-27-5    110-13-4   
N-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxamide 

[1]Bhandari,Namratha;Gaonkar,SantoshL.[ChemistryofHeterocyclicCompounds,2015,vol.51,#4,p.320-323][Khim.Geterotsikl.Soedin.,2015,vol.51,#4,p.320-323,4]

[2]Yaleetal.[JournaloftheAmericanChemicalSociety,1953,vol.75,p.1933,1934]CurrentPatentAssignee:OLINCORP-US2727896,1952,A

[1]BulletindelaSocieteChimiquedeFrance,1976,p.621-627

[1]ComptesRendusdesSeancesdel'AcademiedesSciences,SerieC:SciencesChimiques,1976,vol.283,p.487-489

[1]ArchivderPharmazieundBerichtederDeutschenPharmazeutischenGesellschaft,1970,vol.303,p.310-317

[2]AustralianJournalofChemistry,2005,vol.58,p.891-900

Literature

Title: (1Z,2E)-N'-{1-[2-(4-Bromo-phen-yl)hydrazin-1-yl-idene]-1-chloro-propan-2-yl-idene}thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: 2-(5-Bromo-pyridin-3-yl)-5-[3-(4,5,6,7-tetra-hydro-thieno[3,2-c]pyridine-5-ylsulfon-yl)thio-phen-2-yl]-1,3,4-oxa-diazole.

Journal: Acta crystallographica. Section E, Structure reports online 20111001

Title: 2-(Biphenyl-4-yl)-5-[3-(4,5,6,7-tetra-hydro-thieno[3,2-c]pyridine-5-ylsulfon-yl)thio-phen-2-yl]-1,3,4-oxa-diazole.

Journal: Acta crystallographica. Section E, Structure reports online 20111001

Title: N'-[1-(2-Hy-droxy-phen-yl)ethyl-idene]thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: N'-Benzyl-idene-thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20100901

Title: N'-(4-Hy-droxy-benzyl-idene)thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry.

Journal: Nature chemistry 20100601

Title: N'-(4-Methyl-benzyl-idene)thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: (E)-N'-(4-Methoxy-benzyl-idene)thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: N'-(4-Cyano-benzyl-idene)thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: N'-(4-Bromo-benzyl-idene)thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: N'-(4-Chloro-benzyl-idene)thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: N'-[(5-Methyl-2-fur-yl)methyl-ene]thio-phene-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Lipophilic aroylhydrazone chelator HNTMB and its multiple effects on ovarian cancer cells.

Journal: BMC cancer 20100101

Title: Multinuclear magnetic resonance, electrospray ionization-mass spectroscopy, and parametric method 5 studies of a new derivative of gossypol with 2-thiophenecarbohydrazide as well as its complexes with LI+, Na+, K+, RB+, and Cs+ cations.

Journal: Biopolymers 20061015

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.

Journal: The Journal of biological chemistry 20050506

Title: Reduction of tetrazolium salts containing heterocyclic compounds by tubercle bacilli.

Journal: The American review of respiratory disease 19730101

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