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Title: [Determination of nabumetone and 6-methoxy-2-naphthylacetic acid in plasma using HPLC with UV and MS detection].
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Title: In vitro characterization of the cytochrome P450 isoforms involved in the metabolism of 6-methoxy-2-napthylacetic acid, an active metabolite of the prodrug nabumetone.
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Title: Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.
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Title: Applicability of LC/MS/MS assay for 6-methoxy-2-napthylacetic acid to support the bioequivalence study of nabumetone-comments on the research work of Patel et al. (2008).
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Title: A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090501
Title: Serum protein binding displacement: theoretical analysis using a hypothetical radiopharmaceutical and experimental analysis with 123I-N-isopropyl-p-iodoamphetamine.
Journal: Nuclear medicine and biology 20090101
Title: High-throughput LC-MS/MS assay for 6-methoxy-2-naphthylacetic acid, an active metabolite of nabumetone in human plasma and its application to bioequivalence study.
Journal: Biomedical chromatography : BMC 20081101
Title: Effect of a nonprotein bioactive agent on the reduction of cyclooxygenase-2 and tumor necrosis factor-alpha in human intervertebral disc cells in vitro.
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Title: Theoretical study of the phototoxicity of naproxen and the active form of nabumetone.
Journal: The journal of physical chemistry. A 20081030
Title: Simultaneous determination of two anti-inflammatory drugs in serum using isopotential fluorimetry.
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Title: Safety of the nonselective NSAID nabumetone : focus on gastrointestinal tolerability.
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Title: Synthesis and evaluation of some gastrointestinal sparing anti-inflammatory aminoethyl ester derivatives of naphthalene-based NSAIDs.
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Title: Evaluation of hydroxyimine as cytochrome P450-selective prodrug structure.
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Title: Photosensitizing properties of 6-methoxy-2-naphthylacetic acid, the major metabolite of the phototoxic non-steroidal anti-inflammatory and analgesic drug nabumetone.
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Title: Simplex optimization of the variables affecting the micelle-stabilized room temperature phosphorescence of 6-methoxy-2-naphthylacetic acid and its kinetic determination in human urine.
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Title: Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
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Title: Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA.
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Title: Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis.
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Title: Comparative biotransformation and disposition studies of nabumetone in humans and minipigs using high-performance liquid chromatography with ultraviolet, fluorescence and mass spectrometric detection.
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Title: Non-steroidal anti-inflammatory drug, nabumetone, prevents indometacin-induced gastric damage via inhibition of neutrophil functions.
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Title: The role of cyclooxygenase-2 in lumbar disc herniation.
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Title: Evidence for the involvement of cyclooxygenase activity in the development of cocaine sensitization.
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Title: 2, 4-diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum.
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Title: Renal effects of nabumetone, a COX-2 antagonist: impairment of function in isolated perfused rat kidneys contrasts with preserved renal function in vivo.
Journal: Experimental nephrology 20010101
