Home PEG Linkers 24342-68-5
24342-68-5,MFCD06797107
Catalog No.:AA003G61

24342-68-5 | Hexaethylene glycol monobenzyl ether

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$11.00   $8.00
- +
250mg
98%
in stock  
$13.00   $9.00
- +
2g
95%
in stock  
$38.00   $27.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003G61
Chemical Name:
Hexaethylene glycol monobenzyl ether
CAS Number:
24342-68-5
Molecular Formula:
C19H32O7
Molecular Weight:
372.4532
MDL Number:
MFCD06797107
SMILES:
OCCOCCOCCOCCOCCOCCOCc1ccccc1
Properties
Properties
 
Form:
Liquid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
273  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
19  
XLogP3:
0.2  

Downstream Synthesis Route

[1]Loiseau,FrancoisA.;Hii,KingKuok;Hill,AlisonM.[JournalofOrganicChemistry,2004,vol.69,#3,p.639-647]

[2]Locationinpatent:experimentalpartHolt,DanielJ.;Payne,RichardJ.;Abell,Chris[JournalofFluorineChemistry,2010,vol.131,#3,p.398-407]

[3]Locationinpatent:experimentalpartSimeone,Luca;Mangiapia,Gaetano;Irace,Carlo;DiPascale,Antonio;Colonna,Alfredo;Ortona,Ornella;DeNapoli,Lorenzo;Montesarchio,Daniela;Paduano,Luigi[MolecularBioSystems,2011,vol.7,#11,p.3075-3086]

[4]Riccardi,Claudia;Fàbrega,Carme;Grijalvo,Santiago;Vitiello,Giuseppe;D'Errico,Gerardino;Eritja,Ramon;Montesarchio,Daniela[JournalofMaterialsChemistryB,2018,vol.6,#33,p.5368-5384]

[5]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-US6355646,2002,B1Locationinpatent:Pagecolumn22

[6]CurrentPatentAssignee:XDCEXPLORERSHANGHAI-US10449258,2019,B2Locationinpatent:Page/Pagecolumn161;162;164

[7]Jain,Ahamindra;Huang,ShawG.;Whitesides,GeorgeM.[JournaloftheAmericanChemicalSociety,1994,vol.116,#12,p.5057-5062]

[8]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-US2004/67202,2004,A1

[1]Gartiser,Thierry;Selve,Claude;Mansuy,Laurence;Robert,Alain;Delpuech,Jean-Jacques[JournalofChemicalResearch,Miniprint,1984,#9,p.2672-2691]

[2]CurrentPatentAssignee:BIOCONLIMITED-US2003/228275,2003,A1Locationinpatent:Page41

[3]CurrentPatentAssignee:BIOCONLIMITED-US2003/229009,2003,A1Locationinpatent:Page37

[4]Selve,C.;Achilefu,S.;Mansuy,L.[SyntheticCommunications,1990,vol.20,#6,p.799-807]

[5]ButterworthIV;Moran;Whitesides;Strichartz[JournalofMedicinalChemistry,1987,vol.30,#8,p.1295-1302]

[6]CurrentPatentAssignee:BIOCONLIMITED-US2003/27995,2003,A1

[7]CurrentPatentAssignee:BIOCONLIMITED-US2003/27748,2003,A1CurrentPatentAssignee:BIOCONOY;BIOCONLIMITED-US2003/60606,2003,A1

[1]Loiseau,FrancoisA.;Hii,KingKuok;Hill,AlisonM.[JournalofOrganicChemistry,2004,vol.69,#3,p.639-647]

[2]Selve,C.;Achilefu,S.;Mansuy,L.[SyntheticCommunications,1990,vol.20,#6,p.799-807]

[3]Jain,Ahamindra;Huang,ShawG.;Whitesides,GeorgeM.[JournaloftheAmericanChemicalSociety,1994,vol.116,#12,p.5057-5062]

24342-68-5    69502-33-6   
1-(2H-tetrahydropyran-2-yloxy)-5-vinyloxy-3-oxapentane 
  669556-53-0 

[1]Loiseau,FrancoisA.;Hii,KingKuok;Hill,AlisonM.[JournalofOrganicChemistry,2004,vol.69,#3,p.639-647]

24342-68-5    669556-37-0   
2-2-(2-{2-2-(2-vinyloxy-ethoxy)-ethoxy-ethoxy}-ethoxy)-ethoxy-tetrahydro-pyran 
 
C36H64O14 

[1]Loiseau,FrancoisA.;Hii,KingKuok;Hill,AlisonM.[JournalofOrganicChemistry,2004,vol.69,#3,p.639-647]

Literature

Title: Shaoyun Xiang, et al. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses there. Patent WO2016197946A1.

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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