2441-41-0,MFCD00153471
Catalog No.:AA00BE7T

2441-41-0 | PalGly

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$25.00   $18.00
- +
1g
97%
in stock  
$51.00   $36.00
- +
5g
97%
in stock  
$169.00   $118.00
- +
25g
98%
in stock  
$797.00 $558.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00BE7T
Chemical Name:
PalGly
CAS Number:
2441-41-0
Molecular Formula:
C18H35NO3
Molecular Weight:
313.4754
MDL Number:
MFCD00153471
SMILES:
CCCCCCCCCCCCCCCC(=O)NCC(=O)O
Properties
Properties
 
Form:
Solid  
Solubility:
DMSO: >10mg/mL  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
280  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
16  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
6.5  

Downstream Synthesis Route

[1]Koebner[JournaloftheChemicalSociety,1941,p.565]

[1]Koebner[JournaloftheChemicalSociety,1941,p.565]

[1]An,Dong;Feng,Dexin[ChemicalPapers,2019,vol.73,#3,p.653-662]

[2]Bondi;Frankl[BiochemischeZeitschrift,1909,vol.17,p.552]

[3]CurrentPatentAssignee:LIFEGROUP-EP799188,1999,B1

[4]Qiao,Weihong;Qiao,Yangyang[JournalofSurfactantsandDetergents,2013,vol.16,#6,p.821-828]

[5]Ohsedo,Yutaka;Oono,Masashi;Saruhashi,Kowichiro;Watanabe,Hisayuki[RSCAdvances,2014,vol.4,#89,p.48554-48558]

[6]An,Dong;Zhao,Xiaohui;Ye,Zhiwen[CarbohydrateResearch,2015,vol.414,p.32-38]

[1]JournalofMassSpectrometry,1995,vol.30,p.900-910

[2]Patent:US2012/35108,2012,A1.Locationinpatent:Page/Pagecolumn9

[3]Patent:US9265833,2016,B2.Locationinpatent:Page/Pagecolumn25

[4]ChemicalandPharmaceuticalBulletin,1987,vol.35,p.2935-2942

[5]CanadianJournalofChemistry,1976,vol.54,p.733-737

2441-41-0   
sodiumsaltofglycylglycine 
  83871-31-2 

[1]Iyer,VenkataramanN.;Sheth,GeetaN.;Subrahmanyam,V.V.R.[JournaloftheIndianChemicalSociety,1982,vol.59,#7,p.856-859]

Literature

Title: Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase.

Journal: Bioorganic & medicinal chemistry 20120601

Title: Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging.

Journal: International journal of cosmetic science 20100201

Title: N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.

Journal: BMC neuroscience 20100101

Title: Orphan endogenous lipids and orphan GPCRs: a good match.

Journal: Prostaglandins & other lipid mediators 20090901

Title: Novel endogenous N-acyl glycines identification and characterization.

Journal: Vitamins and hormones 20090101

Title: Acylamido analogs of endocannabinoids selectively inhibit cancer cell proliferation.

Journal: Bioorganic & medicinal chemistry 20081115

Title: A single mutation in P450BM-3 enhances acyl homoserine lactone: acyl homoserine substrate binding selectivity nearly 250-fold.

Journal: Journal of biotechnology 20080731

Title: N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons.

Journal: Molecular pharmacology 20080701

Title: Natural variation of potato allene oxide synthase 2 causes differential levels of jasmonates and pathogen resistance in Arabidopsis.

Journal: Planta 20080701

Title: Interactions of substrates at the surface of P450s can greatly enhance substrate potency.

Journal: Biochemistry 20071211

Title: Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed 'proximal-distal' transition probed by temperature-jump spectroscopy.

Journal: The journal of physical chemistry. B 20070712

Title: Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.

Journal: Journal of the American Chemical Society 20070523

Title: Potential anti-inflammatory actions of the elmiric (lipoamino) acids.

Journal: Bioorganic & medicinal chemistry 20070515

Title: Conformational dynamics of substrate in the active site of cytochrome P450 BM-3/NPG complex: insights from NMR order parameters.

Journal: Journal of the American Chemical Society 20070124

Title: Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.

Journal: Journal of the American Chemical Society 20060503

Title: Structure-guided recombination creates an artificial family of cytochromes P450.

Journal: PLoS biology 20060501

Title: Observation of ligand binding to cytochrome P450 BM-3 by means of solid-state NMR spectroscopy.

Journal: Journal of the American Chemical Society 20051012

Title: Thermal equilibrium of high- and low-spin forms of cytochrome P450 BM-3: repositioning of the substrate?

Journal: Journal of the American Chemical Society 20051005

Title: Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components.

Journal: Plant physiology 20040401

Title: HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides.

Journal: Biological & pharmaceutical bulletin 20030801

Title: Pivotal role of water in the mechanism of P450BM-3.

Journal: Biochemistry 20011113

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Additional Info:
SDS
Historical Records
Tags:2441-41-0 Molecular Formula|2441-41-0 MDL|2441-41-0 SMILES|2441-41-0 PalGly
Catalog No.: AA00BE7T
2441-41-0,MFCD00153471
2441-41-0 | PalGly
Pack Size: 250mg
Purity: 97%
in stock
$25.00 $18.00
Pack Size: 1g
Purity: 97%
in stock
$51.00 $36.00
Pack Size: 5g
Purity: 97%
in stock
$169.00 $118.00
Pack Size: 25g
Purity: 98%
in stock
$797.00 $558.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00BE7T
Chemical Name: PalGly
CAS Number: 2441-41-0
Molecular Formula: C18H35NO3
Molecular Weight: 313.4754
MDL Number: MFCD00153471
SMILES: CCCCCCCCCCCCCCCC(=O)NCC(=O)O
Properties
Form: Solid  
Solubility: DMSO: >10mg/mL  
Storage: Keep in dry area;2-8℃;  
Complexity: 280  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 22  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 16  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 6.5  
Downstream Synthesis Route
67-56-1    2441-41-0    214706-34-0 

[1]Koebner[JournaloftheChemicalSociety,1941,p.565]

64-17-5    2441-41-0    59660-78-5 

[1]Koebner[JournaloftheChemicalSociety,1941,p.565]

56-40-6    112-67-4    2441-41-0 

[1]An,Dong;Feng,Dexin[ChemicalPapers,2019,vol.73,#3,p.653-662]

[2]Bondi;Frankl[BiochemischeZeitschrift,1909,vol.17,p.552]

[3]CurrentPatentAssignee:LIFEGROUP-EP799188,1999,B1

[4]Qiao,Weihong;Qiao,Yangyang[JournalofSurfactantsandDetergents,2013,vol.16,#6,p.821-828]

[5]Ohsedo,Yutaka;Oono,Masashi;Saruhashi,Kowichiro;Watanabe,Hisayuki[RSCAdvances,2014,vol.4,#89,p.48554-48558]

[6]An,Dong;Zhao,Xiaohui;Ye,Zhiwen[CarbohydrateResearch,2015,vol.414,p.32-38]

14464-31-4    56-40-6    2441-41-0 

[1]JournalofMassSpectrometry,1995,vol.30,p.900-910

[2]Patent:US2012/35108,2012,A1.Locationinpatent:Page/Pagecolumn9

[3]Patent:US9265833,2016,B2.Locationinpatent:Page/Pagecolumn25

[4]ChemicalandPharmaceuticalBulletin,1987,vol.35,p.2935-2942

[5]CanadianJournalofChemistry,1976,vol.54,p.733-737

2441-41-0   
sodiumsaltofglycylglycine 
  83871-31-2 

[1]Iyer,VenkataramanN.;Sheth,GeetaN.;Subrahmanyam,V.V.R.[JournaloftheIndianChemicalSociety,1982,vol.59,#7,p.856-859]

Literature fold

Title: Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase.

Journal: Bioorganic & medicinal chemistry20120601

Title: Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging.

Journal: International journal of cosmetic science20100201

Title: N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.

Journal: BMC neuroscience20100101

Title: Orphan endogenous lipids and orphan GPCRs: a good match.

Journal: Prostaglandins & other lipid mediators20090901

Title: Novel endogenous N-acyl glycines identification and characterization.

Journal: Vitamins and hormones20090101

Title: Acylamido analogs of endocannabinoids selectively inhibit cancer cell proliferation.

Journal: Bioorganic & medicinal chemistry20081115

Title: A single mutation in P450BM-3 enhances acyl homoserine lactone: acyl homoserine substrate binding selectivity nearly 250-fold.

Journal: Journal of biotechnology20080731

Title: N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons.

Journal: Molecular pharmacology20080701

Title: Natural variation of potato allene oxide synthase 2 causes differential levels of jasmonates and pathogen resistance in Arabidopsis.

Journal: Planta20080701

Title: Interactions of substrates at the surface of P450s can greatly enhance substrate potency.

Journal: Biochemistry20071211

Title: Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed 'proximal-distal' transition probed by temperature-jump spectroscopy.

Journal: The journal of physical chemistry. B20070712

Title: Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.

Journal: Journal of the American Chemical Society20070523

Title: Potential anti-inflammatory actions of the elmiric (lipoamino) acids.

Journal: Bioorganic & medicinal chemistry20070515

Title: Conformational dynamics of substrate in the active site of cytochrome P450 BM-3/NPG complex: insights from NMR order parameters.

Journal: Journal of the American Chemical Society20070124

Title: Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.

Journal: Journal of the American Chemical Society20060503

Title: Structure-guided recombination creates an artificial family of cytochromes P450.

Journal: PLoS biology20060501

Title: Observation of ligand binding to cytochrome P450 BM-3 by means of solid-state NMR spectroscopy.

Journal: Journal of the American Chemical Society20051012

Title: Thermal equilibrium of high- and low-spin forms of cytochrome P450 BM-3: repositioning of the substrate?

Journal: Journal of the American Chemical Society20051005

Title: Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components.

Journal: Plant physiology20040401

Title: HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides.

Journal: Biological & pharmaceutical bulletin20030801

Title: Pivotal role of water in the mechanism of P450BM-3.

Journal: Biochemistry20011113

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