Home Other Building Blocks 2443-66-5
2443-66-5,MFCD00038133
Catalog No.:AA003RCW

2443-66-5 | 2-Hydroxy-2-phenylacetohydrazide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97
in stock  
$50.00   $35.00
- +
5g
97%
in stock  
$61.00   $43.00
- +
25g
97
in stock  
$287.00   $201.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003RCW
Chemical Name:
2-Hydroxy-2-phenylacetohydrazide
CAS Number:
2443-66-5
Molecular Formula:
C8H10N2O2
Molecular Weight:
166.1772
MDL Number:
MFCD00038133
SMILES:
NNC(=O)C(c1ccccc1)O
Properties
Properties
 
BP:
420.9°C at 760 mmHg  
Form:
Solid  
MP:
134-136°C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
155  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-0.4  

Downstream Synthesis Route
MANDELICACID 
  2443-66-5 

[1]Berger[JournalfurpraktischeChemie(Leipzig1954),1939,vol.<2>152,p.267,314]

[2]CurrentPatentAssignee:GUIZHOUUNIVERSITY-CN108997253,2018,A

[3]Wu,Dehua;Song,Jintong;Qu,Lang;Zhou,Weilan;Wang,Lei;Zhou,Xiangge;Xiang,Haifeng[Chemistry-AnAsianJournal,2020,vol.15,#20,p.3370-3378]

[4]Hou,Shuaitao;Xie,Dewen;Yang,Jingxin;Niu,Xue;Hu,Deyu;Wu,Zhibing[ChemicalBiologyandDrugDesign,2021,vol.98,#1,p.166-174]

[5]CurrentPatentAssignee:GUIZHOUUNIVERSITY-CN113563281,2021,A

[1]Curtius;Mueller[ChemischeBerichte,1901,vol.34,p.2796]

[2]Cave;Galons;Miocque;Rinjard;Tran;Binet[EuropeanJournalofMedicinalChemistry,1990,vol.25,#1,p.75-79]

[3]Masuyama,Araki;Tsuchiya,Kikuo;Okahara,Mitsuo[BulletinoftheChemicalSocietyofJapan,1985,vol.58,#10,p.2855-2859]

[1]Galons;Cave;Miocque;Rinjard;Tran;Binet[EuropeanJournalofMedicinalChemistry,1990,vol.25,#9,p.785-788]

[1]Galons;Cave;Miocque;Rinjard;Tran;Binet[EuropeanJournalofMedicinalChemistry,1990,vol.25,#9,p.785-788]

2443-66-5    74-88-4   
C11H16N2O2 

[1]Masuyama,Araki;Tsuchiya,Kikuo;Okahara,Mitsuo[BulletinoftheChemicalSocietyofJapan,1985,vol.58,#10,p.2855-2859]

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Rational design of new antituberculosis agents: receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives.

Journal: Journal of medicinal chemistry 20040715

Title: Chemotherapy of experimental tuberculosis. V. Isonicotinic acid hydrazide (nydrazid) and related compounds.

Journal: American review of tuberculosis 19520401

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