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2480-28-6,MFCD12828775
Catalog No.:AA002PEN

2480-28-6 | L-Arginine, N2-methyl-

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Purity
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5mg
96%
in stock  
$336.00   $235.00
- +
10mg
96%
in stock  
$486.00   $340.00
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50mg
96%
in stock  
$1,699.00   $1,189.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002PEN
Chemical Name:
L-Arginine, N2-methyl-
CAS Number:
2480-28-6
Molecular Formula:
C7H16N4O2
Molecular Weight:
188.2275
MDL Number:
MFCD12828775
SMILES:
CN[C@H](C(=O)O)CCCNC(=N)N
Properties
Computed Properties
 
Complexity:
189  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
-3.7  

Literature

Title: PCB126 induces apoptosis of chondrocytes via ROS-dependent pathways.

Journal: Osteoarthritis and cartilage 20121001

Title: Impaired increase of retinal capillary blood flow to flicker light exposure in arterial hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20120901

Title: 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection.

Journal: Neuropharmacology 20120801

Title: Endogenous regulators of NO bioavailability in rats with acute renal failure.

Journal: Bulletin of experimental biology and medicine 20120801

Title: DNA demethylation and USF regulate the meiosis-specific expression of the mouse Miwi.

Journal: PLoS genetics 20120501

Title: First-in-class, dual-action, 3,5-disubstituted indole derivatives having human nitric oxide synthase (nNOS) and norepinephrine reuptake inhibitory (NERI) activity for the treatment of neuropathic pain.

Journal: Journal of medicinal chemistry 20120412

Title: Influence of blood flow on arteriolar wall-to-lumen ratio in the human retinal circulation in vivo.

Journal: Microvascular research 20120301

Title: Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20120215

Title: The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities.

Journal: The Biochemical journal 20120201

Title: Optimization of the separation of NDA-derivatized methylarginines by capillary and microchip electrophoresis.

Journal: Journal of laboratory automation 20120201

Title: Nitric oxide-mediated endothlium-dependent vasodilation is impaired with borderline high-LDL cholesterol.

Journal: Clinical and translational science 20120201

Title: The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Journal: PloS one 20120101

Title: Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.

Journal: PloS one 20120101

Title: Nitric oxide manipulation: a therapeutic target for peripheral arterial disease?

Journal: Cardiology research and practice 20120101

Title: Crystal structure of a complex of DNA with one AT-hook of HMGA1.

Journal: PloS one 20120101

Title: Stimulus-specific blockade of nitric oxide-mediated dilatation by asymmetric dimethylarginine (ADMA) and monomethylarginine (L-NMMA) in rat aorta and carotid artery.

Journal: European journal of pharmacology 20111230

Title: Reduction of nitric oxide level enhances the radiosensitivity of hypoxic non-small cell lung cancer.

Journal: Cancer science 20111201

Title: Angiotensin-converting enzyme 2 overexpression improves central nitric oxide-mediated sympathetic outflow in chronic heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20111201

Title: Small-molecular virulence inhibitors show divergent and immunomodulatory effects in infection models of Salmonella enterica serovar Typhimurium.

Journal: International journal of antimicrobial agents 20111101

Title: Interleukin-6 treatment induces beta-cell apoptosis via STAT-3-mediated nitric oxide production.

Journal: Diabetes/metabolism research and reviews 20111101

Title: Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110701

Title: Effects of polycythemia on systemic endothelial function in chronic hypoxic lung disease.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20110501

Title: Involvement of nitric oxide in learning & memory processes.

Journal: The Indian journal of medical research 20110501

Title: The toxic effect of fluoride on MG-63 osteoblast cells is also dependent on the production of nitric oxide.

Journal: Chemico-biological interactions 20110425

Title: Bactericidal oncocin derivatives with superior serum stabilities.

Journal: International journal of antimicrobial agents 20110201

Title: Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101

Title: Basal nitric oxide activity is an independent determinant of arteriolar structure in the human retinal circulation.

Journal: Journal of hypertension 20110101

Title: Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors.

Journal: Platelets 20110101

Title: Conformational-dependent and independent RNA binding to the fragile x mental retardation protein.

Journal: Journal of nucleic acids 20110101

Title: Effects of stem cell factor on hypoxia-inducible factor 1 alpha accumulation in human acute myeloid leukaemia and LAD2 mast cells.

Journal: PloS one 20110101

Title: Targets in epigenetics: inhibiting the methyl writers of the histone code.

Journal: Current chemical genomics 20110101

Title: Protein methylation and stress granules: posttranslational remodeler or innocent bystander?

Journal: Molecular biology international 20110101

Title: The Role of Protein Arginine Methylation in mRNP Dynamics.

Journal: Molecular biology international 20110101

Title: Drug discovery toward antagonists of methyl-lysine binding proteins.

Journal: Current chemical genomics 20110101

Title: Negative association of L-arginine methylation products with oocyte numbers.

Journal: Human reproduction (Oxford, England) 20101201

Title: Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells.

Journal: Yonsei medical journal 20101101

Title: Daily low-dose folic acid supplementation does not prevent nitroglycerin-induced nitric oxide synthase dysfunction and tolerance: a human in vivo study.

Journal: The Canadian journal of cardiology 20101101

Title: Effects of central administration of insulin or l-NMMA on rat skeletal muscle microvascular perfusion.

Journal: Diabetes, obesity & metabolism 20101001

Title: Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.

Journal: Acta histochemica 20100901

Title: Hypercapnic acidosis reduces oxidative reactions in endotoxin-induced lung injury.

Journal: Anesthesiology 20100701

Title: TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei.

Journal: Eukaryotic cell 20100601

Title: Analysis of arginine and methylated metabolites in human plasma by field amplified sample injection capillary electrophoresis tandem mass spectrometry.

Journal: Electrophoresis 20100601

Title: Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression.

Journal: Oncogene 20100527

Title: Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production.

Journal: The FEBS journal 20100501

Title: The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease.

Journal: Current cardiology reviews 20100501

Title: Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction.

Journal: International journal of molecular medicine 20100401

Title: Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke.

Journal: Atherosclerosis 20100201

Title: Rmt1 catalyzes zinc-finger independent arginine methylation of ribosomal protein Rps2 in Saccharomyces cerevisiae.

Journal: Biochemical and biophysical research communications 20100122

Title: Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells.

Journal: Free radical research 20100101

Title: Identification of arginine- and lysine-methylation in the proteome of Saccharomyces cerevisiae and its functional implications.

Journal: BMC genomics 20100101

Title: The Fischer 344 rat reflects human susceptibility to francisella pulmonary challenge and provides a new platform for virulence and protection studies.

Journal: PloS one 20100101

Title: Nitric oxide and pulmonary hypertension.

Journal: Korean journal of anesthesiology 20100101

Title: Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function.

Journal: PloS one 20100101

Title: The endothelium and its role in regulating vascular tone.

Journal: The open cardiovascular medicine journal 20100101

Title: Dimethylarginines and serotonin in the blood of spontaneously hypertensive rats.

Journal: Bulletin of experimental biology and medicine 20091201

Title: Wall-to-lumen ratio of retinal arterioles is related with urinary albumin excretion and altered vascular reactivity to infusion of the nitric oxide synthase inhibitor N-monomethyl-L-arginine.

Journal: Journal of hypertension 20091101

Title: Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides.

Journal: Bioorganic & medicinal chemistry 20091015

Title: Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090901

Title: Role of pICLn in methylation of Sm proteins by PRMT5.

Journal: The Journal of biological chemistry 20090807

Title: Regulation of myometrial contractivity during pregnancy in the rat: potential role for DDAH.

Journal: Molecular human reproduction 20090801

Title: The GH/IGF-1 Axis and Heart Failure.

Journal: Current cardiology reviews 20090801

Title: Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090701

Title: Regulation of alveolar gas conductance by NO in man, as based on studies with NO donors and inhibitors of NO production.

Journal: Acta physiologica (Oxford, England) 20090601

Title: ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide.

Journal: American journal of physiology. Renal physiology 20090601

Title: A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei.

Journal: The Journal of biological chemistry 20090424

Title: HPLC analysis of asymmetric dimethylarginine (ADMA) and related arginine metabolites in human plasma using a novel non-endogenous internal standard.

Journal: Clinica chimica acta; international journal of clinical chemistry 20090301

Title: Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090201

Title: From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases.

Journal: BMC pulmonary medicine 20090101

Title: Imaging cytoplasmic cAMP in mouse brainstem neurons.

Journal: BMC neuroscience 20090101

Title: Deregulation of hepatic insulin sensitivity induced by central lipid infusion in rats is mediated by nitric oxide.

Journal: PloS one 20090101

Title: Regulation of peripheral blood flow in complex regional pain syndrome: clinical implication for symptomatic relief and pain management.

Journal: BMC musculoskeletal disorders 20090101

Title: The role of exercise on L-arginine nitric oxide pathway in chronic heart failure.

Journal: The open biochemistry journal 20090101

Title: Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks.

Journal: PloS one 20090101

Title: Arginine and methylated arginines in human plasma and urine measured by tandem mass spectrometry without the need for chromatography or sample derivatisation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081015

Title: Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure.

Journal: European heart journal 20081001

Title: Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation.

Journal: Clinical biochemistry 20081001

Title: Role of nitric oxide in the visible light-induced rapid increase of human skin microcirculation at the local and systemic levels: II. healthy volunteers.

Journal: Photomedicine and laser surgery 20081001

Title: Arginase and pulmonary diseases.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080801

Title: Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial function in patients with type 2 diabetes.

Journal: Pharmacogenetics and genomics 20080801

Title: Distribution of NOS isoforms in a porcine endotoxin shock model.

Journal: Shock (Augusta, Ga.) 20080601

Title: Histone modifications and chromatin dynamics: a focus on filamentous fungi.

Journal: FEMS microbiology reviews 20080501

Title: Inducible nitric oxide synthase (iNOS) is not required for IL-2-induced hypotension and vascular leak syndrome in mice.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20080501

Title: Nitric oxide stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells.

Journal: Plastic and reconstructive surgery 20080501

Title: Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants.

Journal: Osteoarthritis and cartilage 20080401

Title: Intra-arterial vitamin C prevents endothelial dysfunction caused by ischemia-reperfusion.

Journal: Atherosclerosis 20080301

Title: Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine.

Journal: The Journal of organic chemistry 20080201

Title: Nitric oxide-mediated anxiolytic-like and antidepressant-like effects in animal models of anxiety and depression.

Journal: Pharmacology, biochemistry, and behavior 20080101

Title: Involvement of accumulated NOS inhibitors and endothelin-1, enhanced arginase, and impaired DDAH activities in pulmonary dysfunction following subarachnoid hemorrhage in the rabbit.

Journal: Vascular pharmacology 20080101

Title: Control of muscle mitochondria by insulin entails activation of Akt2-mtNOS pathway: implications for the metabolic syndrome.

Journal: PloS one 20080101

Title: Intracellular signalling by C-peptide.

Journal: Experimental diabetes research 20080101

Title: Effects of Mirtogenol on ocular blood flow and intraocular hypertension in asymptomatic subjects.

Journal: Molecular vision 20080101

Title: Impact of the L-arginine-Nitric Oxide Pathway and Oxidative Stress on the Pathogenesis of the Metabolic Syndrome.

Journal: The open biochemistry journal 20080101

Title: Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide.

Journal: The Prostate 20071201

Title: Assessment of protein-incorporated arginine methylation in biological specimens by CZE UV-detection.

Journal: Electrophoresis 20071201

Title: Inducible nitric oxide synthase attenuates adrenergic signaling in alcohol fed rats.

Journal: Journal of cardiovascular pharmacology 20071201

Title: Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction.

Journal: Circulation 20071113

Title: Enhancement of the sensitivity of the whole-blood gamma interferon assay for diagnosis of Mycobacterium bovis infections in cattle.

Journal: Clinical and vaccine immunology : CVI 20071101

Title: Alterations of NOS, arginase, and DDAH protein expression in rabbit cavernous tissue after administration of cigarette smoke extract.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20071101

Title: Developmental effects of perinatal exposure to extremely weak 7 Hz magnetic fields and nitric oxide modulation in the Wistar albino rat.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20071101

Title: In vitro antihydatic action of IFN-gamma is dependent on the nitric oxide pathway.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20070901

Title: Nitric oxide from both exogenous and endogenous sources activates mitochondria-dependent events and induces insults to human chondrocytes.

Journal: Journal of cellular biochemistry 20070815

Title: Nitric oxide synthase inhibition prevents leptin induced Gn-RH release in prepubertal and peripubertal female rats.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070701

Title: Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: Decreased intrahepatic response to alpha(1)-adrenergic agonists in lipopolysaccharide-treated rats is located in the sinusoidal area and depends on Kupffer cell function.

Journal: Journal of gastroenterology and hepatology 20070601

Title: Chromatographic-mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070515

Title: Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070501

Title: [Differential expression of isocitrate lyase in P. marneffei phagocytized by nonstimulated and stimulated murine macrophages].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070501

Title: Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free-radical-mediated mechanism.

Journal: Journal of the American College of Cardiology 20070327

Title: Endogenous thyrocyte-produced nitric oxide inhibits iodide uptake and thyroid-specific gene expression in FRTL-5 thyroid cells.

Journal: The Journal of endocrinology 20070301

Title: Manganese stimulates luteinizing hormone releasing hormone secretion in prepubertal female rats: hypothalamic site and mechanism of action.

Journal: The Journal of physiology 20070201

Title: Hepatic parasympathetic role in insulin resistance on an animal model of hypertension.

Journal: Metabolism: clinical and experimental 20070201

Title: Hepatic-dependent and -independent insulin actions are impaired in the obese Zucker rat model.

Journal: Obesity (Silver Spring, Md.) 20070201

Title: Modulation of synaptic and channel activities in the respiratory network of the mice by NO/cGMP signalling pathways.

Journal: Brain research 20070126

Title: Bovine natural killer cells restrict the replication of Mycobacterium bovis in bovine macrophages and enhance IL-12 release by infected macrophages.

Journal: Tuberculosis (Edinburgh, Scotland) 20070101

Title: Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070101

Title: Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis to nitric oxide correlates with disease severity in Tegumentary Leishmaniasis.

Journal: BMC infectious diseases 20070101

Title: Altered collecting duct adenylyl cyclase content in collecting duct endothelin-1 knockout mice.

Journal: BMC nephrology 20070101

Title: Possible involvement of enhanced arginase activity due to up-regulated arginases and decreased hydroxyarginine in accelerating intimal hyperplasia with hyperglycemia.

Journal: Vascular pharmacology 20070101

Title: Pretreatment with N-nitro-L-arginine methyl ester improved oxygenation after inhalation of nitric oxide in newborn piglets with Escherichia coli pneumonia and sepsis.

Journal: Journal of Korean medical science 20061201

Title: Evidence for the role of nitric oxide in antiapoptotic and genotoxic effect of nicotine on human gingival fibroblasts.

Journal: Apoptosis : an international journal on programmed cell death 20061101

Title: Mutagenesis of the supF gene of pSP189 replicating in AD293 cells cocultivated with activated macrophages: roles of nitric oxide and reactive oxygen species.

Journal: Chemical research in toxicology 20061101

Title: Nitric oxide is formed in Medicago truncatula-Sinorhizobium meliloti functional nodules.

Journal: Molecular plant-microbe interactions : MPMI 20060901

Title: Adenosine triphosphate inhibits endothelin-1 production by rat inner medullary collecting duct cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20060601

Title: Protective effect of spironolactone on endothelial cell apoptosis.

Journal: Endocrinology 20060501

Title: Increased phosphodiesterase-5 expression is involved in the decreased vasodilator response to nitric oxide in cirrhotic rat livers.

Journal: Journal of hepatology 20060501

Title: FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues.

Journal: Biochemical and biophysical research communications 20060407

Title: Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine.

Journal: Neuroreport 20060403

Title: Rapid nongenomic effects of aldosterone on the renal vasculature in humans.

Journal: Hypertension (Dallas, Tex. : 1979) 20060401

Title: Effect of nos inhibition on retinal arterial and capillary circulation in early arterial hypertension.

Journal: Retina (Philadelphia, Pa.) 20060401

Title: Quantitative assessment of arginine methylation in free versus protein-incorporated amino acids in vitro and in vivo using protein hydrolysis and high-performance liquid chromatography.

Journal: BioTechniques 20060301

Title: Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover.

Journal: Diabetologia 20060201

Title: Differential growth of IFN-beta-engineered tumor cells in nude and IFN receptor-null mice.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060201

Title: Mechanisms involved in the swelling of erythrocytes caused by Pacific and Caribbean ciguatoxins.

Journal: Blood cells, molecules & diseases 20060101

Title: Asymmetric dimethylarginine (ADMA) as a target for pharmacotherapy.

Journal: Pharmacological reports : PR 20060101

Title: PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA.

Journal: Retrovirology 20060101

Title: 17Beta-estradiol effects on human coronaries and grafts employed in myocardial revascularization: a preliminary study.

Journal: Journal of cardiothoracic surgery 20060101

Title: Biological role of glutathione in nitric oxide-induced toxicity in cell culture and animal models.

Journal: Free radical biology & medicine 20051201

Title: Systemic inflammation induces apoptosis with variable vulnerability of different brain regions.

Journal: Journal of chemical neuroanatomy 20051001

Title: Adrenomedullin causes coronary vasodilation in humans: effects of inhibition of nitric oxide synthesis.

Journal: Journal of cardiovascular pharmacology 20051001

Title: Mechanisms of adenosine-induced renal vasodilatation in hypertensive patients.

Journal: Journal of hypertension 20050901

Title: Vasoconstrictor hyporeactivity can be reversed by antioxidants in patients with advanced alcoholic cirrhosis of the liver and ascites.

Journal: Critical care medicine 20050901

Title: Solanum nigrum produces nitric oxide via nuclear factor-kappaB activation in mouse peritoneal macrophages.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20050801

Title: Basal endothelial nitric oxide release is preserved in overweight and obese adults.

Journal: Obesity research 20050801

Title: Quantification of ADMA: analytical approaches.

Journal: Vascular medicine (London, England) 20050701

Title: Are STATS arginine-methylated?

Journal: The Journal of biological chemistry 20050610

Title: Proinflammatory liver and antiinflammatory intestinal mediators involved in portal hypertensive rats.

Journal: Mediators of inflammation 20050609

Title: Nitric oxide mediates the effect of fluvastatin on intercellular adhesion molecule-1 and platelet endothelial cell adhesion molecule-1 expression on human endothelial cells.

Journal: Annals of vascular surgery 20050501

Title: Effects of isoprostane on tubuloglomerular feedback: roles of TP receptors, NOS, and salt intake.

Journal: American journal of physiology. Renal physiology 20050401

Title: Reduced agonist-induced endothelium-dependent vasodilation in uremia is attributable to an impairment of vascular nitric oxide.

Journal: Journal of the American Society of Nephrology : JASN 20050401

Title: The nicorandil-induced vasodilation in humans is inhibited by miconazole.

Journal: Journal of cardiovascular pharmacology 20050401

Title: Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.

Journal: Bioorganic & medicinal chemistry letters 20050401

Title: Endogenous nitric oxide mediates lipoteichoic acid induced preconditioning on reoxygenation injury of cultured human coronary artery endothelial cells.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050401

Title: The role of NO in macrophage dysfunction at early stage after burn injury.

Journal: Burns : journal of the International Society for Burn Injuries 20050301

Title: Novel and orally bioavailable inducible nitric oxide synthase inhibitors: synthesis and evaluation of optically active 4,5-dialkyl-2-iminoselenazolidine derivatives.

Journal: Bioorganic & medicinal chemistry letters 20050301

Title: Continuous cytokine exposure of colonic epithelial cells induces DNA damage.

Journal: European journal of gastroenterology & hepatology 20050301

Title: Prophylactic high-dose N(omega)-monomethyl-L-arginine prevents the late cardiac dysfunction associated with lethal tumor necrosis factor-alpha challenge in dogs.

Journal: Shock (Augusta, Ga.) 20050301

Title: Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine.

Journal: The Journal of biological chemistry 20050218

Title: eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.

Journal: Regulatory peptides 20050215

Title: PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine.

Journal: The Journal of biological chemistry 20050204

Title: Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function.

Journal: BMC biology 20050101

Title: Effects of soy isoflavones on endothelial function in healthy postmenopausal women.

Journal: Menopause (New York, N.Y.) 20050101

Title: Asymmetric dimethylarginine: a molecule responsible for the coexistence of insulin resistance and atherosclerosis via dual nitric oxide synthase inhibition.

Journal: Medical hypotheses 20050101

Title: Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Renal blood flow in sepsis.

Journal: Critical care (London, England) 20050101

Title: [The importance of regulation of endogenous methylarginine concentrations in clinical practice].

Journal: Przeglad lekarski 20050101

Title: Reducing arginase activity via dietary manganese deficiency enhances endothelium-dependent vasorelaxation of rat aorta.

Journal: Experimental biology and medicine (Maywood, N.J.) 20041201

Title: Low sodium diet inhibits the local counter-regulator effect of angiotensin-(1-7) on angiotensin II.

Journal: Journal of hypertension 20041201

Title: Hemodynamic and sympathoadrenal responses to mental stress during nitric oxide synthesis inhibition.

Journal: American journal of physiology. Heart and circulatory physiology 20041101

Title: Glutamate induces apoptosis in anterior pituitary cells through group II metabotropic glutamate receptor activation.

Journal: Endocrinology 20041001

Title: beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine.

Journal: Journal of hypertension 20041001

Title: Contribution of interaction between nitric oxide and cyclooxygenases to the production of prostaglandins in carrageenan-induced inflammation.

Journal: Anesthesiology 20041001

Title: Simultaneous determination of L-arginine and its mono- and dimethylated metabolites in human plasma by high-performance liquid chromatography-mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20041001

Title: Inhibition of l-arginine transport in platelets by asymmetric dimethylarginine and N-monomethyl-l-arginine: effects of arterial hypertension.

Journal: Clinical and experimental pharmacology & physiology 20041001

Title: Nitric oxide pathway in the nucleus raphe magnus modulates hypoxic ventilatory response but not anapyrexia in rats.

Journal: Brain research 20040813

Title: Functional role of the Na+/H+ exchanger in the regulation of cerebral arteriolar tone in rats.

Journal: Journal of neurosurgery 20040801

Title: Accumulated endogenous nitric oxide synthase inhibitors in inhibiting urethral relaxation following estrogen supplementation in ovariectomized rabbits.

Journal: The Journal of urology 20040701

Title: Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit.

Journal: The Journal of urology 20040701

Title: The cardiovascular effects of nitric oxide and carbon monoxide in the nucleus tractus solitarii of rats.

Journal: Journal of hypertension 20040601

Title: Neuropeptide Y enhances permeability across a rat aortic endothelial cell monolayer.

Journal: American journal of physiology. Heart and circulatory physiology 20040301

Title: Cerivastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide.

Journal: European journal of pharmacology 20040206

Title: Effects of imidapril, an angiotensin-converting enzyme inhibitor, on insulin sensitivity and responsiveness in streptozotocin-induced diabetic rats.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040101

Title: Ability of T cell subsets and their soluble mediators to modulate the replication of Mycobacterium bovis in bovine macrophages.

Journal: Cellular immunology 20040101

Title: Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence.

Journal: Circulation 20031216

Title: Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis.

Journal: Journal of cellular physiology 20031201

Title: Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells.

Journal: Biochemical pharmacology 20031101

Title: Nitric oxide produced by murine dendritic cells is cytotoxic for intracellular Salmonella enterica sv. Typhimurium.

Journal: Scandinavian journal of immunology 20031101

Title: Interleukin-6 protects MIN6 beta cells from cytokine-induced apoptosis.

Journal: Annals of the New York Academy of Sciences 20031101

Title: Falcarindiol inhibits nitric oxide-mediated neuronal death in lipopolysaccharide-treated organotypic hippocampal cultures.

Journal: Neuroreport 20031027

Title: Excessive production of nitric oxide induces the neuronal cell death in lipopolysaccharide-treated rat hippocampal slice culture.

Journal: Neuroscience letters 20030925

Title: The HMG-CoA reductase inhibitor cerivastatin enhances the nitric oxide bioavailability of the endothelium.

Journal: Journal of cardiovascular pharmacology 20030901

Title: Effects of overexpression of dimethylarginine dimethylaminohydrolase on tumor angiogenesis assessed by susceptibility magnetic resonance imaging.

Journal: Cancer research 20030815

Title: Melatonin attenuates alpha-adrenergic-induced contractions by increasing the release of vasoactive intestinal peptide in isolated rat penile bulb.

Journal: Urological research 20030801

Title: Nitric oxide in the rostral ventrolateral medulla modulates hyperpnea but not anapyrexia induced by hypoxia.

Journal: Brain research 20030711

Title: Heme oxygenase-1 induction by endogenous nitric oxide: influence of intracellular glutathione.

Journal: FEBS letters 20030710

Title: Kidney transplantation improves endothelium-dependent vasodilation in patients with endstage renal disease.

Journal: Transplantation 20030615

Title: Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke.

Journal: Annals of neurology 20030601

Title: AT1-receptor antagonism improves endothelial function in coronary artery disease by a bradykinin/B2-receptor-dependent mechanism.

Journal: Hypertension (Dallas, Tex. : 1979) 20030501

Title: Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants.

Journal: Toxicon : official journal of the International Society on Toxinology 20030501

Title: Platelet-activating factor synthesis by neutrophils, monocytes, and endothelial cells is modulated by nitric oxide production.

Journal: Shock (Augusta, Ga.) 20030401

Title: Effect of high-dose statin treatment on plasma concentrations of endogenous nitric oxide synthase inhibitors.

Journal: Journal of cardiovascular pharmacology 20030201

Title: Interleukin-1beta inhibits ATP-induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide.

Journal: British journal of pharmacology 20030201

Title: Regulation of NF-kappaB activation by protein phosphatase 2B and NO, via protein kinase A activity, in human monocytes.

Journal: Nitric oxide : biology and chemistry 20030201

Title: HIF-1 alpha protein as a target for S-nitrosation.

Journal: FEBS letters 20030130

Title: Renal hemodynamic and ureteral pressure changes in response to ureteral obstruction: the role of nitric oxide.

Journal: The Journal of urology 20030101

Title: House dust mite Dermatophagoides farinae augments proinflammatory mediator productions and accessory function of alveolar macrophages: implications for allergic sensitization and inflammation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030101

Title: Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells.

Journal: The Journal of biological chemistry 20021220

Title: Prostaglandins are involved in acetylcholine- and 5-hydroxytryptamine-induced, nitric oxide-mediated vasodilatation in human forearm.

Journal: Journal of cardiovascular pharmacology 20021201

Title: C-reactive protein relaxes human vessels in vitro.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20021101

Title: Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion.

Journal: International journal of cancer 20021010

Title: Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis.

Journal: British journal of cancer 20020909

Title: Role of propofol and its solvent, intralipid, in nitric oxide-induced peripheral vasodilatation in dogs.

Journal: British journal of anaesthesia 20020901

Title: Changes in blood pressure and heart rate by repetitive transcranial magnetic stimulation in rats.

Journal: Neuroscience letters 20020823

Title: Superoxide activates constitutive nitric oxide synthase in a brain particulate fraction.

Journal: Biochemical and biophysical research communications 20020816

Title: Activated factor XII levels and factor XII 46C>T genotype in relation to coronary artery calcification in patients with type 1 diabetes and healthy subjects.

Journal: Atherosclerosis 20020801

Title: Peroxynitrite and the regulation of Na(+),K(+)-ATPase activity by angiotensin II in the rat proximal tubule.

Journal: Nitric oxide : biology and chemistry 20020801

Title: Genotoxicity associated with NO production in macrophages and co-cultured target cells.

Journal: Free radical biology & medicine 20020701

Title: Regulation by reactive oxygen species of interleukin-1beta, nitric oxide and prostaglandin E(2) production by human chondrocytes.

Journal: Osteoarthritis and cartilage 20020701

Title: Nitric oxide and blood pressure in mice lacking extracellular-superoxide dismutase.

Journal: Free radical research 20020701

Title: High glucose induced nuclear factor kappa B mediated inhibition of endothelial cell migration.

Journal: Atherosclerosis 20020601

Title: Glioma-associated hyaluronan induces apoptosis in dendritic cells via inducible nitric oxide synthase: implications for the use of dendritic cells for therapy of gliomas.

Journal: Cancer research 20020501

Title: Host systemic and local nitric oxide levels do not correlate with rejection of pig proislet xenografts in mice.

Journal: Xenotransplantation 20020501

Title: Expression of TGF-betas and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes.

Journal: Osteoarthritis and cartilage 20020501

Title: Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography.

Journal: Analytical biochemistry 20020415

Title: Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice.

Journal: Nitric oxide : biology and chemistry 20020301

Title: Specific expression of Bax-omega in pancreatic beta-cells is down-regulated by cytokines before the onset of apoptosis.

Journal: Endocrinology 20020101

Title: Effect of pravastatin on responsiveness to N-monomethyl-L-arginine in patients with hypercholesterolaemia.

Journal: Atherosclerosis 20020101

Title: Cytokine-induced expression of tPA is differentially modulated by NO and ROS in rat mesangial cells.

Journal: Kidney international 20020101

Title: Progress in the development of selective nitric oxide synthase (NOS) inhibitors.

Journal: Current pharmaceutical design 20020101

Title: An automated analyzer for methylated arginines in rat plasma by high-performance liquid chromatography with post-column fluorescence reaction.

Journal: The Analyst 20020101

Title: Effects of estrogen in the regulation of nitric oxide pathway during development of hypertension in rats.

Journal: Proceedings of the Western Pharmacology Society 20020101

Title: Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011201

Title: Regulation of nitric oxide production by murine peritoneal macrophages treated in vitro with chemokine monocyte chemoattractant protein 1.

Journal: Nitric oxide : biology and chemistry 20011201

Title: Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20011115

Title: Inhibition of nitric oxide synthase initiates relapsing remitting experimental autoimmune encephalomyelitis in rats, yet nitric oxide appears to be essential for clinical expression of disease.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20011115

Title: Endothelial function and myogenic reactivity in small mesenteric arteries of hyperlipidemic pregnant rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011001

Title: Peroxynitrite-induced nitrotyrosination of proteins is blocked by direct 5-lipoxygenase inhibitor zileuton.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Peripheral nitric oxide in carrageenan-induced inflammation.

Journal: Brain research 20010907

Title: Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study.

Journal: Circulation 20010904

Title: Nitric oxide dependence of renal blood flow in patients with renal artery stenosis.

Journal: Journal of the American Society of Nephrology : JASN 20010901

Title: Cigarette smoking in men and vascular responsiveness.

Journal: British journal of clinical pharmacology 20010801

Title: Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia.

Journal: Circulation 20010724

Title: Lisinopril improves endothelial function in chronic cigarette smokers.

Journal: Clinical science (London, England : 1979) 20010701

Title: Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa.

Journal: The American journal of pathology 20010701

Title: Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTC rat hepatoma cells.

Journal: Journal of hepatology 20010701

Title: Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein.

Journal: The Journal of biological chemistry 20010601

Title: Role of heparin and nitric oxide in the cardiac and regional hemodynamic properties of protamine in conscious chronically instrumented dogs.

Journal: Anesthesiology 20010601

Title: Methylation of histone H3 by coactivator-associated arginine methyltransferase 1.

Journal: Biochemistry 20010515

Title: Activation-induced cell death of rat astrocytes.

Journal: Brain research 20010511

Title: Carboxypeptidase D is up-regulated in raw 264.7 macrophages and stimulates nitric oxide synthesis by cells in arginine-free medium.

Journal: Molecular pharmacology 20010501

Title: Hypoxic pulmonary vasoconstriction increases during endotoxemia in the perfused rat lung.

Journal: The Journal of trauma 20010501

Title: Activation of stress-activated protein kinase in osteoarthritic cartilage: evidence for nitric oxide dependence.

Journal: Osteoarthritis and cartilage 20010501

Title: Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide production.

Journal: The Journal of biological chemistry 20010406

Title: Comparison of cardiac and regional hemodynamic responses to N-methyl-L-arginine and aminoguanidine infusions in conscious pigs.

Journal: Journal of cardiovascular pharmacology 20010401

Title: Nitric oxide differentially regulates induction of type II nitric oxide synthase in rat vascular smooth muscle cells versus macrophages.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20010401

Title: Preservation of venous endothelial function in the forearm venous capacitance bed of patients with chronic heart failure despite arterial endothelial dysfunction.

Journal: Journal of the American College of Cardiology 20010315

Title: NO/cGMP signaling modulates regulation of Na+-K+-ATPase activity by angiotensin II in rat proximal tubules.

Journal: American journal of physiology. Renal physiology 20010301

Title: Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow.

Journal: Kidney international 20010301

Title: Transforming growth factor-beta(1) stimulates L-arginine transport and metabolism in vascular smooth muscle cells: role in polyamine and collagen synthesis.

Journal: Circulation 20010227

Title: Role of nitric oxide in the airway response to exercise in healthy and asthmatic subjects.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010201

Title: Altered effects of potassium channel modulation in the coronary circulation in experimental hypercholesterolemia.

Journal: Atherosclerosis 20010201

Title: Phenanthrenequinone disrupts progesterone production in rat luteal cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: Titration of low K(d) binding sites: binding of arginine analogs to nitric oxide synthases.

Journal: Nitric oxide : biology and chemistry 20010101

Title: 1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line.

Journal: Infection and immunity 19981101

Title: Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.

Journal: Infection and immunity 19950201

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Tags:2480-28-6 Molecular Formula|2480-28-6 MDL|2480-28-6 SMILES|2480-28-6 L-Arginine, N2-methyl-