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249889-64-3,MFCD06411602
Catalog No.:AA002Q0B

249889-64-3 | Sb-334867

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
in stock  
$184.00   $129.00
- +
10mg
in stock  
$254.00   $178.00
- +
50mg
in stock  
$718.00   $503.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA002Q0B
Chemical Name:
Sb-334867
CAS Number:
249889-64-3
Molecular Formula:
C17H14ClN5O2
Molecular Weight:
355.7784
MDL Number:
MFCD06411602
SMILES:
O=C(Nc1ccnc2c1nccc2)Nc1ccc2c(c1)oc(n2)C.Cl
Properties
Computed Properties
 
Complexity:
462  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2  

Literature

Title: Porter RA, et al. 1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor.Bioorg Med Chem Lett. 2001 Jul 23;11(14):1907-10.

Title: Łupina M, et al. SB-334867 (an Orexin-1 Receptor Antagonist) Effects on Morphine-Induced Sensitization in Mice-a View on Receptor Mechanisms.

Title: Anderson RI, et al. Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models.Front Neurosci. 2014 Feb 25;8:33.

Title: Smart D, et al. SB-334867-A: the first selective orexin-1 receptor antagonist.Br J Pharmacol. 2001 Mar;132(6):1179-82.

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SDS
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Tags:249889-64-3 Molecular Formula|249889-64-3 MDL|249889-64-3 SMILES|249889-64-3 Sb-334867
Catalog No.: AA002Q0B
249889-64-3,MFCD06411602
249889-64-3 | Sb-334867
Pack Size： 5mg
Purity：
in stock
$184.00 $129.00
Pack Size： 10mg
Purity：
in stock
$254.00 $178.00
Pack Size： 50mg
Purity：
in stock
$718.00 $503.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA002Q0B
Chemical Name: Sb-334867
CAS Number: 249889-64-3
Molecular Formula: C17H14ClN5O2
Molecular Weight: 355.7784
MDL Number: MFCD06411602
SMILES: O=C(Nc1ccnc2c1nccc2)Nc1ccc2c(c1)oc(n2)C.Cl
Properties
Complexity: 462  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 24  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2  
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