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2504-32-7,MFCD11978028
Catalog No.:AA002Q71

2504-32-7 | 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-

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Purity
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5mg
≥98%
in stock  
$89.00   $62.00
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10mg
≥98%
in stock  
$165.00   $115.00
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25mg
≥98%
in stock  
$278.00   $194.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002Q71
Chemical Name:
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-
CAS Number:
2504-32-7
Molecular Formula:
C18H14ClNO4
Molecular Weight:
343.7611
MDL Number:
MFCD11978028
SMILES:
OC(=O)Cc1c2cc(O)ccc2n(c1C)C(=O)c1ccc(cc1)Cl
Properties
Properties
 
Form:
Solid  
MP:
>190°C (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
491  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
3.9  

Literature

Title: An evaluation of myeloperoxidase-mediated bio-activation of NSAIDs in promyelocytic leukemia (HL-60) cells for potential cytotoxic selectivity.

Journal: Toxicology letters 20171005

Title: Structure-based design, synthesis, and biological evaluation of indomethacin derivatives as cyclooxygenase-2 inhibiting nitric oxide donors.

Journal: Journal of medicinal chemistry 20071213

Title: The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo.

Journal: Pharmacological research 20071001

Title: Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2.

Journal: Molecular pharmacology 20050301

Title: Molecular basis of the time-dependent inhibition of cyclooxygenases by indomethacin.

Journal: Biochemistry 20041214

Title: Alpha2-adrenoceptor mediated co-release of dopamine and noradrenaline from noradrenergic neurons in the cerebral cortex.

Journal: Journal of neurochemistry 20040201

Title: Decrements in per pulse release of norepinephrine, antagonist potentiation of release and presynaptic receptor theory.

Journal: Brain research bulletin 20030715

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SDS
Tags:2504-32-7 Molecular Formula|2504-32-7 MDL|2504-32-7 SMILES|2504-32-7 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-