Title: Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationships.
Journal: Journal of natural products 20110527
Title: Total synthesis of TAK-kinase inhibitor LL-Z1640-2 via consecutive macrocyclization and transannular aromatization.
Journal: Organic letters 20101203
Title: Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III.
Journal: Bioorganic & medicinal chemistry letters 20100515
Title: Conformational analyses and MO studies of f152A1 and its analogues as potent protein kinase inhibitors.
Journal: Journal of chemical information and modeling 20091201
Title: Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20091102
Title: E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-1 and MEK kinase-1: in vitro characterization of its anti-inflammatory and antihyperproliferative activities.
Journal: The Journal of pharmacology and experimental therapeutics 20091101
Title: Role of a cysteine residue in the active site of ERK and the MAPKK family.
Journal: Biochemical and biophysical research communications 20070216
Title: Chemistry and biology of resorcylic acid lactones.
Journal: Chemical communications (Cambridge, England) 20070107
Title: Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells.
Journal: Toxicology and applied pharmacology 20040415
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