Title: A novel mutation in VKORC1 and its effect on enzymatic activity in Japanese warfarin-resistant rats.
Journal: The Journal of veterinary medical science 20130201
Title: Functional study of the vitamin K cycle in mammalian cells.
Journal: Blood 20110310
Title: Novel insight into the mechanism of the vitamin K oxidoreductase (VKOR): electron relay through Cys43 and Cys51 reduces VKOR to allow vitamin K reduction and facilitation of vitamin K-dependent protein carboxylation.
Journal: The Journal of biological chemistry 20110304
Title: Ethnic differences in the population pharmacokinetics and pharmacodynamics of warfarin.
Journal: Journal of pharmacokinetics and pharmacodynamics 20100201
Title: A possible ethanol-catalyzed rearrangement of vitamin K(1) detected by gas chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20081201
Title: Structure and function of vitamin K epoxide reductase.
Journal: Vitamins and hormones 20080101
Title: Vitamin K-dependent carboxylation.
Journal: Vitamins and hormones 20080101
Title: The conversion of vitamin K epoxide to vitamin K quinone and vitamin K quinone to vitamin K hydroquinone uses the same active site cysteines.
Journal: Biochemistry 20070619
Title: Disulfide-dependent protein folding is linked to operation of the vitamin K cycle in the endoplasmic reticulum. A protein disulfide isomerase-VKORC1 redox enzyme complex appears to be responsible for vitamin K1 2,3-epoxide reduction.
Journal: The Journal of biological chemistry 20070126
Title: Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20061219
Title: Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin.
Journal: Thrombosis and haemostasis 20051001
Title: Species comparison of vitamin K1 2,3-epoxide reductase activity in vitro: kinetics and warfarin inhibition.
Journal: Toxicology 20030801
Title: Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16.
Journal: Blood 20021101
Title: Characterization and purification of the vitamin K1 2,3 epoxide reductases system from rat liver.
Journal: The Journal of pharmacy and pharmacology 20010401
Title: The association of vitamin K status with warfarin sensitivity at the onset of treatment.
Journal: British journal of haematology 20010301
Title: Mechanism of the abnormal vitamin K-dependent gamma-carboxylation process in human hepatocellular carcinomas.
Journal: Cancer 19940901
Title: Patulin biosynthesis: epoxidation of toluquinol and gentisyl alcohol by particulate preparations from Penicillium patulum.
Journal: Biochemistry 19891114
