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26048-05-5,MFCD30541349
Catalog No.:AA002RFT

26048-05-5 | Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$199.00   $139.00
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10mg
≥95%
in stock  
$373.00   $261.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002RFT
Chemical Name:
Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]
CAS Number:
26048-05-5
Molecular Formula:
C22H27N3O9
Molecular Weight:
477.4645
MDL Number:
MFCD30541349
SMILES:
O=C1OCC(=O)NC(Cc2ccccc2)C(=O)OC(C(C)C)C(=O)NCC(=O)OCC(=O)NC1
Properties
Properties
 
Form:
Solid  
MP:
>145°C (Subl.)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
1200  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
57  
Hydrogen Bond Acceptor Count:
9  
Rotatable Bond Count:
9  
XLogP3:
8.4  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartToman,Petr;Makrlik,Emanuel;Vanura,Petr[MonatsheftefurChemie,2011,vol.142,#8,p.779-782]

Boc-Me-Phe-D-Hiv-Me-Phe-D-Hiv-Me-Phe-D-Hiv-OBn 
  26048-05-5 

[1]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[1]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[2]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[3]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[1]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[2]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[3]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

benzyl(R)-2-hydroxy-3-methylbutanoate 
  26048-05-5 

[1]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[2]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

[3]Lücke,Daniel;Dalton,Toryn;Ley,StevenV.;Wilson,ZoeE.[Chemistry-AEuropeanJournal,2016,vol.22,#12,p.4206-4217]

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Title: Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo). 1992 Oct;45(10):1626-32.

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