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2614-06-4,MFCD00210220
Catalog No.:AA00BCF5

2614-06-4 | (R)-(+)-THALIDOMIDE

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10mg
2 weeks  
$1,143.00   $800.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BCF5
Chemical Name:
(R)-(+)-THALIDOMIDE
CAS Number:
2614-06-4
Molecular Formula:
C13H10N2O4
Molecular Weight:
258.2295
MDL Number:
MFCD00210220
SMILES:
O=C1CC[C@H](C(=O)N1)N1C(=O)c2c(C1=O)cccc2
Properties
Computed Properties
 
Complexity:
449  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.3  

Literature

Title: Targeting the tumor microenvironment: focus on angiogenesis.

Journal: Journal of oncology 20120101

Title: [The Neurosedyn disaster became a starting shot. The drug approval process was changed and new era of patient safety was initiated].

Journal: Lakartidningen 20111101

Title: Isomin: a novel cytoplasmic intermediate filament protein from an arthropod species.

Journal: BMC biology 20110101

Title: History and phylogeny of intermediate filaments: now in insects.

Journal: BMC biology 20110101

Title: Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil.

Journal: PloS one 20110101

Title: Radiotherapy and 'new' drugs-new side effects?

Journal: Radiation oncology (London, England) 20110101

Title: Evaluating the efficacy of tryptophan fluorescence and absorbance as a selection tool for identifying protein crystals.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20100301

Title: Angiogenesis inhibition in prostate cancer: current uses and future promises.

Journal: Journal of oncology 20100101

Title: The legal standards for the radioactive or non radioactive drugs research and approval in the European Community and in Germany after the thalidomide catastrophe.

Journal: Hellenic journal of nuclear medicine 20100101

Title: Anti-angiogenesis therapies: their potential in cancer management.

Journal: OncoTargets and therapy 20100101

Title: Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1.

Journal: Molecular neurodegeneration 20100101

Title: Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides.

Journal: Bioorganic & medicinal chemistry letters 20090715

Title: Comparison between measurements obtained with three different perineometers.

Journal: Clinics (Sao Paulo, Brazil) 20090601

Title: Effects of inducible nitric oxide synthase inhibition or norepinephrine on the neurovascular coupling in an endotoxic rat shock model.

Journal: Critical care (London, England) 20090101

Title: Progranulin is expressed within motor neurons and promotes neuronal cell survival.

Journal: BMC neuroscience 20090101

Title: [Contergan writes its history (interview by Angelika Staub)].

Journal: Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege 20071201

Title: Evaluation of chemical and photochemical oxidation processes for degradation of phosmet on lowbush blueberries (Vaccinium angustifolium).

Journal: Journal of agricultural and food chemistry 20061213

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers.

Journal: Environmental health perspectives 20060501

Title: Comparative effectiveness of different insecticides for organic management of blueberry maggot (Diptera: Tephritidae).

Journal: Journal of economic entomology 20050801

Title: Variation in organophosphate pesticide metabolites in urine of children living in agricultural communities.

Journal: Environmental health perspectives 20050401

Title: Teratology in cultural documents and today.

Journal: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20041201

Title: Mechanisms of action and potential therapeutic uses of thalidomide.

Journal: Croatian medical journal 20020601

Title: [On the history of the Contergan (thalidomide) catastrophe in the light of drug legislation].

Journal: Deutsche medizinische Wochenschrift (1946) 20011019

Title: Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Journal: Chemical research in toxicology 20010301

Title: Thalomid (Thalidomide) capsules: a review of the first 18 months of spontaneous postmarketing adverse event surveillance, including off-label prescribing.

Journal: Drug safety 20010101

Title: Thalidomide as an anti-angiogenic agent in relapsed gliomas.

Journal: Journal of neuro-oncology 20010101

Title: Murphy S, et al. Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU. J Pharm Pharmacol. 2007 Jan;59(1):105-14.

Title: Eriksson T, et al. Intravenous formulations of the enantiomers of thalidomide: pharmacokinetic and initial pharmacodynamic characterization in man. J Pharm Pharmacol. 2000 Jul;52(7):807-17.

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Tags:2614-06-4 Molecular Formula|2614-06-4 MDL|2614-06-4 SMILES|2614-06-4 (R)-(+)-THALIDOMIDE