Home Amines 26309-95-5
26309-95-5,MFCD07799965
Catalog No.:AA00C2T0

26309-95-5 | (pivaloyloxy)methyl [2S-[2alpha,5alpha,6beta(S*)]]-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride

This product is typically in stock,please click "Inquire" below or
contact us at [email protected] for pricing and availability information.
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2T0
Chemical Name:
(pivaloyloxy)methyl [2S-[2alpha,5alpha,6beta(S*)]]-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride
CAS Number:
26309-95-5
Molecular Formula:
C22H30ClN3O6S
Molecular Weight:
500.0081
MDL Number:
MFCD07799965
SMILES:
O=C([C@@H](c1ccccc1)N)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)OCOC(=O)C(C)(C)C)(C)C.Cl
Properties
Computed Properties
 
Complexity:
774  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
9  

Literature

Title: Pharmacokinetics in pulmonary epithelial lining fluid and plasma of ampicillin and pivampicillin administered to horses.

Journal: Research in veterinary science 20120201

Title: Kinetic assessment of luminal degradation of orally effective prodrugs for rational drug development.

Journal: Journal of pharmaceutical sciences 20100201

Title: Penicillins vs trimethoprim-based regimens for acute bacterial exacerbations of chronic bronchitis: meta-analysis of randomized controlled trials.

Journal: Canadian family physician Medecin de famille canadien 20090101

Title: Bacampicillin uptake is shared with thiamine in Caco-2 cells.

Journal: Biological & pharmaceutical bulletin 20070701

Title: Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin.

Journal: Antimicrobial agents and chemotherapy 20050401

Title: Intracellular accumulation and activity of ampicillin used as free drug and as its phthalimidomethyl or pivaloyloxymethyl ester (pivampicillin) against Listeria monocytogenes in J774 macrophages.

Journal: The Journal of antimicrobial chemotherapy 20031001

Title: Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin.

Journal: Pharmaceutical research 20030401

Title: Carnitine deficiency associated with long-term pivampicillin treatment: the effect of a replacement therapy regime.

Journal: Postgraduate medical journal 19921101

Title: Effect of beta-lactam prodrugs on human intestinal microflora.

Journal: Scandinavian journal of infectious diseases. Supplementum 19860101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:26309-95-5 Molecular Formula|26309-95-5 MDL|26309-95-5 SMILES|26309-95-5 (pivaloyloxy)methyl [2S-[2alpha,5alpha,6beta(S*)]]-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride