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26864-56-2,MFCD00866714
Catalog No.:AA00I4ZZ

26864-56-2 | 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol

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Purity
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Price(USD)
Quantity
  
200mg
>98.0%(T)
in stock  
$19.00   $13.00
- +
1g
>98.0%(T)
in stock  
$56.00   $40.00
- +
5g
98%(HPLC)
in stock  
$239.00   $167.00
- +
10g
98%(HPLC)
in stock  
$397.00   $278.00
- +
25g
98%(HPLC)
in stock  
$762.00   $534.00
- +
100g
98%
in stock  
$2,007.00   $1,405.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I4ZZ
Chemical Name:
1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
CAS Number:
26864-56-2
Molecular Formula:
C28H27ClF5NO
Molecular Weight:
523.9651
MDL Number:
MFCD00866714
SMILES:
Fc1ccc(cc1)C(c1ccc(cc1)F)CCCN1CCC(CC1)(O)c1ccc(c(c1)C(F)(F)F)Cl
NSC Number:
759179
Properties
Properties
 
BP:
587.7°C at 760 mmHg  
Form:
Solid  
MP:
105-107 °C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
647  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
7.3  

Literature

Title: Calcium-dependent inhibition of adrenal TREK-1 channels by angiotensin II and ionomycin.

Journal: American journal of physiology. Cell physiology 20110901

Title: Clarithromycin, a cytochrome P450 inhibitor, can reverse mefloquine resistance in Plasmodium yoelii nigeriensis- infected Swiss mice.

Journal: Parasitology 20110801

Title: Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: Identification of novel functional inhibitors of acid sphingomyelinase.

Journal: PloS one 20110101

Title: Impaired cerebellar functional connectivity in schizophrenia patients and their healthy siblings.

Journal: Frontiers in psychiatry 20110101

Title: The position of mefloquine as a 21st century malaria chemoprophylaxis.

Journal: Malaria journal 20100101

Title: An overview of Indian research in schizophrenia.

Journal: Indian journal of psychiatry 20100101

Title: Research on antipsychotics in India.

Journal: Indian journal of psychiatry 20100101

Title: Antipsychotics and risk of venous thromboembolism: A population-based case-control study.

Journal: Clinical epidemiology 20090101

Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal: Journal of medicinal chemistry 20080124

Title: Tourette's syndrome: clinical features, pathophysiology, and therapeutic approaches.

Journal: Dialogues in clinical neuroscience 20070601

Title: Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review.

Journal: The Journal of clinical psychiatry 20060901

Title: Penfluridol for schizophrenia.

Journal: The Cochrane database of systematic reviews 20060419

Title: Brief psychotic disorder associated with Sturge-Weber syndrome.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20050601

Title: Safety of haloperidol and penfluridol in pregnancy: a multicenter, prospective, controlled study.

Journal: The Journal of clinical psychiatry 20050301

Title: An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1.

Journal: The Journal of biological chemistry 20021220

Title: Differential inhibition of T-type calcium channels by neuroleptics.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020115

Title: LC-MS-MS analysis of the neuroleptics clozapine, flupentixol, haloperidol, penfluridol, thioridazine, and zuclopenthixol in hair obtained from psychiatric patients.

Journal: Journal of analytical toxicology 20020101

Title: Comparative short-term evaluation of penfluridol and trifluoperazine in chronic schizophrenia.

Journal: Indian journal of physiology and pharmacology 19880101

Title: [Pharmacological studies of antipsychotic drug, penfluridol. 2. General pharmacological properties].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19760701

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Tags:26864-56-2 Molecular Formula|26864-56-2 MDL|26864-56-2 SMILES|26864-56-2 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol