[1]BioorganicandMedicinalChemistryLetters,2001,vol.11,p.2235-2239
[2]Patent:US2003/186990,2003,A1
[3]Patent:US2003/114472,2003,A1
[4]Patent:EP1282607,2015,B1.Locationinpatent:Paragraph0099
[1]BioorganicandMedicinalChemistryLetters,2001,vol.11,p.2235-2239
[2]Patent:WO2012/1695,2012,A1
[3]Patent:US2013/96148,2013,A1
[4]Patent:US2015/336900,2015,A1
[1]BioorganicandMedicinalChemistryLetters,2001,vol.11,p.2235-2239
[2]Patent:WO2012/1695,2012,A1
[3]Patent:US2013/96148,2013,A1
[4]Patent:US2015/336900,2015,A1
[1]BioorganicandMedicinalChemistryLetters,2001,vol.11,p.2235-2239
[1]BioorganicandMedicinalChemistryLetters,2001,vol.11,p.2235-2239
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology 20150518
Title: Synthesis and biological evaluation of CHX-DAPYs as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Bioorganic & medicinal chemistry 20140615
Title: Discovery of novel diarylpyrimidines as potent HIV NNRTIs via a structure-guided core-refining approach.
Journal: European journal of medicinal chemistry 20140610
Title: Structural modifications of CH(OH)-DAPYs as new HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Bioorganic & medicinal chemistry 20140415
Title: Discovery of nitropyridine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors via a structure-based core refining approach.
Journal: European journal of medicinal chemistry 20140409
Title: Competitive fitness assays indicate that the E138A substitution in HIV-1 reverse transcriptase decreases in vitro susceptibility to emtricitabine.
Journal: Antimicrobial agents and chemotherapy 20140401
Title: Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 1: design, synthesis and biological evaluation of novel 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives.
Journal: Bioorganic & medicinal chemistry 20140401
Title: Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays.
Journal: Bioorganic & medicinal chemistry 20140315
Title: In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor.
Journal: Antimicrobial agents and chemotherapy 20140301
Title: Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.
Journal: Bioorganic & medicinal chemistry letters 20140201
Title: Evaluation of chitosan nanoformulations as potent anti-HIV therapeutic systems.
Journal: Biochimica et biophysica acta 20140101
Title: Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry 20140101
Title: Increasing extracellular protein concentration reduces intracellular antiretroviral drug concentration and antiviral effect.
Journal: AIDS research and human retroviruses 20131101
Title: In vitro and in vivo activities of AIC292, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor.
Journal: Antimicrobial agents and chemotherapy 20131101
Title: Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies.
Journal: Bioorganic & medicinal chemistry 20131101
Title: Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility.
Journal: Bioorganic & medicinal chemistry letters 20130915
Title: Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry 20130401
Title: DB-02, a C-6-cyclohexylmethyl substituted pyrimidinone HIV-1 reverse transcriptase inhibitor with nanomolar activity, displays an improved sensitivity against K103N or Y181C than S-DABOs.
Journal: PloS one 20130101
Title: Rational design of potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal: Journal of medicinal chemistry 20121213
Title: Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIV-1 reverse transcriptase inhibitors.
Journal: European journal of medicinal chemistry 20121201
Title: Pharmacokinetic interaction between maraviroc and etravirine in HIV-infected patients receiving regimens containing both drugs and no ritonavir-boosted protease inhibitor.
Journal: The Journal of antimicrobial chemotherapy 20121101
Title: Novel method to assess antiretroviral target trough concentrations using in vitro susceptibility data.
Journal: Antimicrobial agents and chemotherapy 20121101
Title: Single- and multiple-dose pharmacokinetics of darunavir plus ritonavir and etravirine in semen and rectal tissue of HIV-negative men.
Journal: Journal of acquired immune deficiency syndromes (1999) 20121001
Title: Immune recovery and T cell subset analysis during effective treatment with maraviroc.
Journal: The Journal of antimicrobial chemotherapy 20121001
Title: Simplification to dual antiretroviral therapy including a ritonavir-boosted protease inhibitor in treatment-experienced HIV-1-infected patients.
Journal: The Journal of antimicrobial chemotherapy 20121001
Title: Antiretroviral neurotoxicity.
Journal: Journal of neurovirology 20121001
Title: Etravirine: a guide to its use in treatment-experienced pediatric patients with HIV-1 infection in the US.
Journal: Paediatric drugs 20121001
Title: Long-term glucose tolerance in highly experienced HIV-infected patients receiving nucleoside analogue-sparing regimens.
Journal: AIDS (London, England) 20120910
Title: High frequency of vitamin D deficiency in HIV-infected patients: effects of HIV-related factors and antiretroviral drugs.
Journal: The Journal of antimicrobial chemotherapy 20120901
Title: Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120901
Title: E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure.
Journal: AIDS (London, England) 20120824
Title: Gastrointestinal-associated lymphoid tissue immune reconstitution in a randomized clinical trial of raltegravir versus non-nucleoside reverse transcriptase inhibitor-based regimens.
Journal: AIDS (London, England) 20120824
Title: Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.
Journal: Journal of medicinal chemistry 20120823
Title: Pooled week 96 results of the phase III DUET-1 and DUET-2 trials of etravirine: further analysis of adverse events and laboratory abnormalities of special interest.
Journal: HIV medicine 20120801
Title: From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework.
Journal: Journal of pharmacokinetics and pharmacodynamics 20120801
Title: New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Journal of medicinal chemistry 20120726
Title: Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors.
Journal: European journal of medicinal chemistry 20120701
Title: Virological failure at one year in triple-class experienced patients switching to raltegravir-based regimens is not predicted by baseline factors.
Journal: International journal of STD & AIDS 20120701
Title: Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.
Journal: Bioorganic & medicinal chemistry 20120615
Title: Efficacy and safety outcomes among treatment-experienced women and men treated with etravirine in gender, race and clinical experience.
Journal: AIDS research and human retroviruses 20120601
Title: Etravirine concentrations in CSF in HIV-infected patients.
Journal: The Journal of antimicrobial chemotherapy 20120601
Title: Dual therapy based on a ritonavir-boosted protease inhibitor as a novel salvage strategy for HIV-1-infected patients on a failing antiretroviral regimen.
Journal: The Journal of antimicrobial chemotherapy 20120601
Title: H2O2 signals via iron induction of VL30 retrotransposition correlated with cytotoxicity.
Journal: Free radical biology & medicine 20120515
Title: Supersaturation in human gastric fluids.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120501
Title: Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: European journal of medicinal chemistry 20120501
Title: Etravirine: a review of its use in the management of treatment-experienced patients with HIV-1 infection.
Journal: Drugs 20120416
Title: Long-term efficacy and safety of raltegravir, etravirine, and darunavir/ritonavir in treatment-experienced patients: week 96 results from the ANRS 139 TRIO trial.
Journal: Journal of acquired immune deficiency syndromes (1999) 20120415
Title: [Leucoencephalopathy in a patient with type I human immunodeficiency virus (HIV-1) infection and symptoms of a hypertensive emergency].
Journal: Enfermedades infecciosas y microbiologia clinica 20120401
Title: Biotransformation of the antiretroviral drug etravirine: metabolite identification, reaction phenotyping, and characterization of autoinduction of cytochrome P450-dependent metabolism.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120401
Title: Prevalence of etravirine resistance associated mutations in HIV-1 strains isolated from infected individuals failing efavirenz: comparison between subtype B and non-B genetic variants.
Journal: Journal of medical virology 20120401
Title: Week 96 outcomes of patients with less treatment experience versus more treatment experience receiving etravirine in the DUET trials.
Journal: Current HIV research 20120401
Title: HIV drug resistance interpreted by cumulative versus last genotypes in HIV-infected patients with multiple treatment failures.
Journal: Current HIV research 20120401
Title: [Reverse transcriptase inhibitors, protease inhibitors].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20120401
Title: Drug interactions between voriconazole, darunavir/ritonavir and etravirine in an HIV-infected patient with Aspergillus pneumonia.
Journal: AIDS (London, England) 20120327
Title: Efficacy of new antiretroviral drugs in treatment-experienced HIV-infected patients: a systematic review and meta-analysis of recent randomized controlled trials.
Journal: HIV medicine 20120301
Title: Intracellular and plasma pharmacokinetics of 400 mg of etravirine once daily versus 200 mg of etravirine twice daily in HIV-infected patients.
Journal: The Journal of antimicrobial chemotherapy 20120301
Title: Lipid profiles for etravirine versus efavirenz in treatment-naive patients in the randomized, double-blind SENSE trial.
Journal: The Journal of antimicrobial chemotherapy 20120301
Title: Pharmacokinetics and short-term safety and tolerability of etravirine in treatment-experienced HIV-1-infected children and adolescents.
Journal: AIDS (London, England) 20120220
Title: Acceptable plasma concentrations of raltegravir and etravirine when administered by gastrostomy tube in a patient with advanced multidrug-resistant human immunodeficiency virus infection.
Journal: Pharmacotherapy 20120201
Title: Cost-effectiveness of combination therapy with etravirine in treatment-experienced adults with HIV-1 infection.
Journal: AIDS (London, England) 20120128
Title: The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*.
Journal: HIV medicine 20120101
Title: Reverse transcriptase genotypes in pediatric patients failing initial antiretroviral therapy in Gaborone, Botswana.
Journal: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20120101
Title: [Safety and effectiveness of salvage therapy in HIV patients].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101
Title: Emerging mutations and associated factors in patients displaying treatment failure on an etravirine-containing regimen.
Journal: Antiviral therapy 20120101
Title: A case of a potential drug interaction between clobazam and etravirine-based antiretroviral therapy.
Journal: Antiviral therapy 20120101
Title: Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings.
Journal: HIV/AIDS (Auckland, N.Z.) 20120101
Title: Virologic failure of protease inhibitor-based second-line antiretroviral therapy without resistance in a large HIV treatment program in South Africa.
Journal: PloS one 20120101
Title: HIV-1 phenotypic reverse transcriptase inhibitor drug resistance test interpretation is not dependent on the subtype of the virus backbone.
Journal: PloS one 20120101
Title: Safety profile of maraviroc in patients coinfected with HIV-1 and hepatitis B or C included in the maraviroc expanded access program.
Journal: HIV clinical trials 20120101
Title: Pharmacokinetics and Pharmacodynamics of Darunavir and Etravirine in HIV-1-Infected, Treatment-Experienced Patients in the Gender, Race, and Clinical Experience (GRACE) Trial.
Journal: AIDS research and treatment 20120101
Title: Impact of Novel Resistance Profiles in HIV-1 Reverse Transcriptase on Phenotypic Resistance to NVP.
Journal: AIDS research and treatment 20120101
Title: New option for management of HIV-1 infection in treatment-naive patients: once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir.
Journal: HIV/AIDS (Auckland, N.Z.) 20120101
Title: Impact of low-level-viremia on HIV-1 drug-resistance evolution among antiretroviral treated-patients.
Journal: PloS one 20120101
Title: Antiretroviral drugs: critical issues and recent advances.
Journal: Indian journal of pharmacology 20120101
Title: Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents.
Journal: Journal of medicinal chemistry 20111222
Title: Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine.
Journal: ChemMedChem 20111209
Title: Short communication prevalence of susceptibility to etravirine by genotype and phenotype in samples received for routine HIV type 1 resistance testing in the United States.
Journal: AIDS research and human retroviruses 20111201
Title: Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry 20111201
Title: Emerging trends of drug-resistant HIV-1 among drug-treated patients in former blood donors in Hubei, China: a three-year surveillance from 2004 to 2006.
Journal: Virologica Sinica 20111201
Title: Does GSS still maintain relevance on HAART outcome after the introduction of newest active antiretroviral drugs? 48 weeks results.
Journal: Current HIV research 20111201
Title: Antiretroviral therapy in Indian setting: when & what to start with, when & what to switch to?
Journal: The Indian journal of medical research 20111201
Title: Phase 2 double-blind, randomized trial of etravirine versus efavirenz in treatment-naive patients: 48-week results.
Journal: AIDS (London, England) 20111128
Title: Role of non-nucleoside reverse transcriptase inhibitors in treating HIV-infected children.
Journal: Drugs 20111112
Title: In vitro activity of antiretroviral drugs against Plasmodium falciparum.
Journal: Antimicrobial agents and chemotherapy 20111101
Title: HIV-1 reverse transcriptase connection subdomain mutations involved in resistance to approved non-nucleoside inhibitors.
Journal: Antiviral research 20111101
Title: Raltegravir dosage adjustment in HIV-infected patients receiving etravirine.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20111101
Title: Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the Western Cape, South Africa.
Journal: Journal of medical virology 20111001
Title: Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
Journal: European journal of medicinal chemistry 20111001
Title: Resistance-associated mutation prevalence according to subtypes B and non-B of HIV type 1 in antiretroviral-experienced patients in Minas Gerais, Brazil.
Journal: AIDS research and human retroviruses 20110901
Title: Effect of mutations at position E138 in HIV-1 reverse transcriptase on phenotypic susceptibility and virologic response to etravirine.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110901
Title: Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry 20110901
Title: A computational study of CYP3A4 mediated drug interaction profiles for anti-HIV drugs.
Journal: Journal of molecular modeling 20110801
Title: Etravirine-based highly active antiretroviral therapy in HIV-1-infected paediatric patients.
Journal: HIV medicine 20110801
Title: Pharmacokinetics of the raltegravir/maraviroc/etravirine combination.
Journal: The Journal of antimicrobial chemotherapy 20110801
Title: Prevalence of etravirine-associated mutations in clinical samples with genotypic resistance to nevirapine and efavirenz in Brazilian clinics.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110801
Title: Short communication: high effectiveness of etravirine in routine clinical practice in treatment-experienced HIV type 1-infected patients.
Journal: AIDS research and human retroviruses 20110701
Title: Cell disposition of raltegravir and newer antiretrovirals in HIV-infected patients: high inter-individual variability in raltegravir cellular penetration.
Journal: The Journal of antimicrobial chemotherapy 20110701
Title: Resistance to antiretroviral drugs in treated and drug-naive patients in the Democratic Republic of Congo.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110701
Title: Endothelial, inflammatory, coagulation, metabolic effects and safety of etravirine in HIV-uninfected volunteers.
Journal: AIDS patient care and STDs 20110601
Title: Selection of nonnucleoside reverse transcriptase inhibitor-associated mutations in HIV-1 subtype C: evidence of etravirine cross-resistance.
Journal: AIDS (London, England) 20110515
Title: HIV-1 integrase inhibitor resistance and its clinical implications.
Journal: The Journal of infectious diseases 20110501
Title: [Characteristics of antiretroviral drugs].
Journal: Enfermedades infecciosas y microbiologia clinica 20110501
Title: Clinical evaluation of the determination of plasma concentrations of darunavir, etravirine, raltegravir and ritonavir in dried blood spot samples.
Journal: Bioanalysis 20110501
Title: CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.
Journal: PLoS pathogens 20110501
Title: Reply to 'Pharmacokinetics of etravirine, raltegravir and darunavir/ritonavir in treatment experienced patients'.
Journal: AIDS (London, England) 20110424
Title: Excipient-mediated supersaturation stabilization in human intestinal fluids.
Journal: Molecular pharmaceutics 20110404
Title: Impact of the N348I mutation in HIV-1 reverse transcriptase on nonnucleoside reverse transcriptase inhibitor resistance in non-subtype B HIV-1.
Journal: Antimicrobial agents and chemotherapy 20110401
Title: Durability and safety of a novel salvage therapy in R5-tropic HIV-infected patients: maraviroc, raltegravir, etravirine.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110401
Title: Safety and pharmacokinetics of etravirine in pregnant HIV-1-infected women.
Journal: HIV medicine 20110401
Title: Clinical management of HIV drug resistance.
Journal: Viruses 20110401
Title: A HPLC-MS method for the simultaneous quantification of fourteen antiretroviral agents in peripheral blood mononuclear cell of HIV infected patients optimized using medium corpuscular volume evaluation.
Journal: Journal of pharmaceutical and biomedical analysis 20110325
Title: Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide.
Journal: Journal of medicinal chemistry 20110324
Title: Atomic force microscopy-based screening of drug-excipient miscibility and stability of solid dispersions.
Journal: Pharmaceutical research 20110301
Title: Levels of adherence required for virologic suppression among newer antiretroviral medications.
Journal: The Annals of pharmacotherapy 20110301
Title: Drug interactions between voriconazole, darunavir/ritonavir and etravirine in an HIV-infected patient with Aspergillus pneumonia.
Journal: AIDS (London, England) 20110220
Title: Theoretical studies on the molecular basis of HIV-1RT/NNRTIs interactions.
Journal: Journal of enzyme inhibition and medicinal chemistry 20110201
Title: Long-term successful control of super-multidrug-resistant human immunodeficiency virus type 1 infection by a novel combination therapy of raltegravir, etravirine, and boosted-darunavir.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110201
Title: HIV-1 drug resistance testing from dried blood spots collected in rural Tanzania using the ViroSeq HIV-1 Genotyping System.
Journal: The Journal of antimicrobial chemotherapy 20110201
Title: Efficacy and safety of nucleoside reverse transcriptase inhibitor-sparing salvage therapy for multidrug-resistant HIV-1 infection based on new-class and new-generation antiretrovirals.
Journal: The Journal of antimicrobial chemotherapy 20110201
Title: Recent FDA approvals and changes.
Journal: AIDS patient care and STDs 20110201
Title: A comparison of neuropsychiatric adverse events during 12 weeks of treatment with etravirine and efavirenz in a treatment-naive, HIV-1-infected population.
Journal: AIDS (London, England) 20110128
Title: SENSE makes us rethink the second-generation nonnucleoside reverse transcriptase inhibitor etravirine's place in HIV-1 treatment.
Journal: AIDS (London, England) 20110128
Title: A randomized crossover study to compare efavirenz and etravirine treatment.
Journal: AIDS (London, England) 20110102
Title: A phase IV, double-blind, multicentre, randomized, placebo-controlled, pilot study to assess the feasibility of switching individuals receiving efavirenz with continuing central nervous system adverse events to etravirine.
Journal: AIDS (London, England) 20110102
Title: Physicochemical properties of the amorphous drug, cast films, and spray dried powders to predict formulation probability of success for solid dispersions: etravirine.
Journal: Journal of pharmaceutical sciences 20110101
Title: Recent advances in antiretroviral drugs.
Journal: Expert opinion on pharmacotherapy 20110101
Title: Pharmacokinetic interactions between etravirine and non-antiretroviral drugs.
Journal: Clinical pharmacokinetics 20110101
Title: Recent advances in DAPYs and related analogues as HIV-1 NNRTIs.
Journal: Current medicinal chemistry 20110101
Title: Indications for the use of next-generation antiretroviral drugs in current clinical practice.
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20110101
Title: Human Herpesvirus-8 Infection Associated with Kaposi Sarcoma, Multicentric Castleman's Disease, and Plasmablastic Microlymphoma in a Man with AIDS: A Case Report with Review of Pathophysiologic Processes.
Journal: Pathology research international 20110101
Title: Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals--the Swiss HIV Cohort Study.
Journal: Journal of translational medicine 20110101
Title: Clinical use of CCR5 inhibitors in HIV and beyond.
Journal: Journal of translational medicine 20110101
Title: A biregional survey and review of first-line treatment failure and second-line paediatric antiretroviral access and use in Asia and southern Africa.
Journal: Journal of the International AIDS Society 20110101
Title: HIV-1 infected patients with suppressed plasma viremia on treatment have pro-inflammatory HDL.
Journal: Lipids in health and disease 20110101
Title: 'Dynamic range' of inferred phenotypic HIV drug resistance values in clinical practice.
Journal: PloS one 20110101
Title: The costs of full suppression of plasma HIV RNA in highly antiretroviral-experienced patients.
Journal: AIDS reviews 20110101
Title: Use of maraviroc-, raltegravir-, and etravirine-containing regimens in treatment-experienced patients: a case-series study.
Journal: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20110101
Title: HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients.
Journal: Virology journal 20110101
Title: Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial.
Journal: PloS one 20110101
Title: Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings.
Journal: AIDS research and treatment 20110101
Title: Protease Inhibitor Resistance Is Uncommon in HIV-1 Subtype C Infected Patients on Failing Second-Line Lopinavir/r-Containing Antiretroviral Therapy in South Africa.
Journal: AIDS research and treatment 20110101
Title: Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in Cameroon.
Journal: Virology journal 20110101
Title: The evolution of HIV-1 reverse transcriptase in route to acquisition of Q151M multi-drug resistance is complex and involves mutations in multiple domains.
Journal: Retrovirology 20110101
Title: Predicted susceptibility of etravirine in HIV patients experiencing virological failure secondary to non-nucleoside reverse transcriptase inhibitor resistance in Argentina.
Journal: Enfermedades infecciosas y microbiologia clinica 20110101
Title: Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis.
Journal: Malaria journal 20110101
Title: Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects.
Journal: PloS one 20110101
Title: Safety and tolerability of antiretrovirals during pregnancy.
Journal: Infectious diseases in obstetrics and gynecology 20110101
Title: A synthetic HIV-1 subtype C backbone generates comparable PR and RT resistance profiles to a subtype B backbone in a recombinant virus assay.
Journal: PloS one 20110101
Title: Contraception in HIV-positive female adolescents.
Journal: AIDS research and therapy 20110101
Title: HIV and HAART-Associated Dyslipidemia.
Journal: The open cardiovascular medicine journal 20110101
Title: High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lomé, Togo.
Journal: Journal of the International AIDS Society 20110101
Title: Similar efficacy of raltegravir when used with or without a protease inhibitor in treatment-experienced patients.
Journal: HIV clinical trials 20110101
Title: Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe.
Journal: PloS one 20110101
Title: The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles.
Journal: Retrovirology 20110101
Title: Human immunodeficiency virus infection and autoimmune hepatitis during highly active anti-retroviral treatment: a case report and review of the literature.
Journal: Journal of medical case reports 20110101
Title: Impact of small body weight on tenofovir-associated renal dysfunction in HIV-infected patients: a retrospective cohort study of Japanese patients.
Journal: PloS one 20110101
Title: Treatment simplification in HIV-infected adults as a strategy to prevent toxicity, improve adherence, quality of life and decrease healthcare costs.
Journal: Patient preference and adherence 20110101
Title: Prevention of perinatal HIV transmission: the Perinatal HIV Hotline perspective.
Journal: Topics in antiviral medicine 20110101
Title: Modeling HIV/AIDS drug price determinants in Brazil: is generic competition a myth?
Journal: PloS one 20110101
Title: Nephrotoxicity of HAART.
Journal: AIDS research and treatment 20110101
Title: HIV-Associated Venous Thromboembolism.
Journal: Mediterranean journal of hematology and infectious diseases 20110101
Title: Health-related quality of life in the gender, race, and clinical experience trial.
Journal: AIDS research and treatment 20110101
Title: Cross-validated stepwise regression for identification of novel non-nucleoside reverse transcriptase inhibitor resistance associated mutations.
Journal: BMC bioinformatics 20110101
Title: A win-win solution?: A critical analysis of tiered pricing to improve access to medicines in developing countries.
Journal: Globalization and health 20110101
Title: Etravirine and rilpivirine resistance in HIV-1 subtype CRF01_AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens.
Journal: Antiviral therapy 20110101
Title: Increase of transmitted drug resistance among HIV-infected sub-Saharan Africans residing in Spain in contrast to the native population.
Journal: PloS one 20110101
Title: It is time to consider third-line options in antiretroviral-experienced paediatric patients?
Journal: Journal of the International AIDS Society 20110101
Title: Safety, efficacy, and pharmacokinetics of rilpivirine: systematic review with an emphasis on resource-limited settings.
Journal: HIV/AIDS (Auckland, N.Z.) 20110101
Title: Role of raltegravir in the management of HIV-1 infection.
Journal: HIV/AIDS (Auckland, N.Z.) 20110101
Title: Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis.
Journal: PloS one 20110101
Title: Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development.
Journal: PloS one 20110101
Title: Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
Journal: Antiviral therapy 20110101
Title: Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract.
Journal: Antiviral therapy 20110101
Title: Rate and determinants of treatment response to different antiretroviral combination strategies in subjects presenting at HIV-1 diagnosis with advanced disease.
Journal: BMC infectious diseases 20110101
Title: Artemether-Lumefantrine Combination Therapy for Treatment of Uncomplicated Malaria: The Potential for Complex Interactions with Antiretroviral Drugs in HIV-Infected Individuals.
Journal: Malaria research and treatment 20110101
Title: Clinical Use of Inhibitors of HIV-1 Integration: Problems and Prospects.
Journal: Acta naturae 20110101
Title: Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Journal: Journal of medicinal chemistry 20101209
Title: Pharmacokinetic evaluation of etravirine.
Journal: Expert opinion on drug metabolism & toxicology 20101201
Title: Maraviroc is a substrate for OATP1B1 in vitro and maraviroc plasma concentrations are influenced by SLCO1B1 521 T>C polymorphism.
Journal: Pharmacogenetics and genomics 20101201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20101201
Title: Comparison of the Mechanisms of Drug Resistance among HIV, Hepatitis B, and Hepatitis C.
Journal: Viruses 20101201
Title: Update of the drug resistance mutations in HIV-1: December 2010.
Journal: Topics in HIV medicine : a publication of the International AIDS Society, USA 20101201
Title: A report from the XVIII International AIDS Conference. (July 18-23, 2010-Vienna, Austria).
Journal: Drugs of today (Barcelona, Spain : 1998) 20101201
Title: LC-MS/MS determination of etravirine in rat plasma and its application in pharmacokinetic studies.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101115
Title: Resistance analyses in highly experienced patients failing raltegravir, etravirine and darunavir/ritonavir regimen.
Journal: AIDS (London, England) 20101113
Title: Raltegravir-induced cerebellar ataxia.
Journal: AIDS (London, England) 20101113
Title: Safety of etravirine in HIV-1/hepatitis B and/or C virus co-infected patients: pooled 96 week results from the Phase III DUET trials.
Journal: The Journal of antimicrobial chemotherapy 20101101
Title: Drug supersaturation in simulated and human intestinal fluids representing different nutritional states.
Journal: Journal of pharmaceutical sciences 20101101
Title: Differential impact of the HIV-1 non-nucleoside reverse transcriptase inhibitor mutations K103N and M230L on viral replication and enzyme function.
Journal: The Journal of antimicrobial chemotherapy 20101101
Title: Characterization of genotypic and phenotypic changes in HIV-1-infected patients with virologic failure on an etravirine-containing regimen in the DUET-1 and DUET-2 clinical studies.
Journal: AIDS research and human retroviruses 20101101
Title: Pharmacokinetics and pharmacodynamics of the non-nucleoside reverse-transcriptase inhibitor etravirine in treatment-experienced HIV-1-infected patients.
Journal: Clinical pharmacology and therapeutics 20101101
Title: A 48-week pilot study switching suppressed patients to darunavir/ritonavir and etravirine from enfuvirtide, protease inhibitor(s), and non-nucleoside reverse transcriptase inhibitor(s).
Journal: AIDS research and human retroviruses 20101101
Title: Virological response with fully active etravirine: pooled results from the DUET-1 and DUET-2 trials.
Journal: International journal of STD & AIDS 20101101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20101101
Title: Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs.
Journal: Viruses 20101101
Title: Pharmacokinetics of etravirine, raltegravir and darunavir/ritonavir in treatment experienced patients.
Journal: AIDS (London, England) 20101023
Title: Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses.
Journal: Bioorganic & medicinal chemistry letters 20101015
Title: HIV-1 drug resistance mutations in children after failure of first-line nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapy.
Journal: HIV medicine 20101001
Title: Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.
Journal: Antimicrobial agents and chemotherapy 20101001
Title: Naturally occurring polymorphisms and primary drug resistance profile among antiretroviral-naive individuals in Bangalore, India.
Journal: AIDS research and human retroviruses 20101001
Title: Etravirine in the treatment of HIV-1: a clinical overview for healthcare professionals.
Journal: Current HIV research 20101001
Title: Pharmacoeconomics of etravirine.
Journal: Expert review of pharmacoeconomics & outcomes research 20101001
Title: Novel antiretroviral combinations in treatment-experienced patients with HIV infection: rationale and results.
Journal: Drugs 20100910
Title: HPLC-MS method for the quantification of nine anti-HIV drugs from dry plasma spot on glass filter and their long term stability in different conditions.
Journal: Journal of pharmaceutical and biomedical analysis 20100905
Title: Prevalence of mutations and determinants of genotypic resistance to etravirine (TMC125) in a large Italian resistance database (ARCA).
Journal: HIV medicine 20100901
Title: Ultrafast and high-throughput mass spectrometric assay for therapeutic drug monitoring of antiretroviral drugs in pediatric HIV-1 infection applying dried blood spots.
Journal: Analytical and bioanalytical chemistry 20100901
Title: Cyanation of arenes via iridium-catalyzed borylation.
Journal: Journal of the American Chemical Society 20100825
Title: Looking for an active conformation of the future HIV type-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Antiviral chemistry & chemotherapy 20100811
Title: A less sensitive detector does not necessarily result in a less sensitive method: fast quantification of 13 antiretroviral analytes in plasma with liquid chromatography coupled with tandem mass spectrometry.
Journal: Clinical chemistry and laboratory medicine 20100801
Title: Methadone, buprenorphine, and street drug interactions with antiretroviral medications.
Journal: Current HIV/AIDS reports 20100801
Title: Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses.
Journal: Bioorganic & medicinal chemistry letters 20100715
Title: Hybrid diarylbenzopyrimidine non-nucleoside reverse transcriptase inhibitors as promising new leads for improved anti-HIV-1 chemotherapy.
Journal: Bioorganic & medicinal chemistry 20100715
Title: Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Journal of medicinal chemistry 20100708
Title: Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations.
Journal: The Journal of antimicrobial chemotherapy 20100701
Title: A review of the safety and tolerability profile of the next-generation NNRTI etravirine.
Journal: AIDS research and human retroviruses 20100701
Title: Etravirine in combination with darunavir/ritonavir and optimized background regimen results in suppression of HIV replication in treatment-experienced patients. Evaluation of Katlama C, Haubrich R, Lalezari J, et al. Efficacy and safety of etravirine in treatment-experienced HIV-1 patients: pooled 48-week analysis of two randomized, controlled trials. AIDS 2009; 23: 2289-300.
Journal: Expert opinion on pharmacotherapy 20100601
Title: Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601
Title: Short communication: activity of etravirine on different HIV type 1 subtypes: in vitro susceptibility in treatment-naive patients and week 48 pooled DUET study data.
Journal: AIDS research and human retroviruses 20100601
Title: Patients infected with HIV type 1 subtype CRF01_AE and failing first-line nevirapine- and efavirenz-based regimens demonstrate considerable cross-resistance to etravirine.
Journal: AIDS research and human retroviruses 20100601
Title: Colloid formation by drugs in simulated intestinal fluid.
Journal: Journal of medicinal chemistry 20100527
Title: Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design.
Journal: Journal of medicinal chemistry 20100527
Title: In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor.
Journal: Antiviral research 20100501
Title: FDA notifications. Etravirine label updated by FDA.
Journal: AIDS alert 20100501
Title: Intracellular and plasma steady-state pharmacokinetics of raltegravir, darunavir, etravirine and ritonavir in heavily pre-treated HIV-infected patients.
Journal: British journal of clinical pharmacology 20100501
Title: A rare case of severe myopathy associated with etravirine use.
Journal: AIDS (London, England) 20100424
Title: Efficacy, safety, and tolerability of etravirine with and without darunavir/ritonavir or raltegravir in treatment-experienced patients: analysis of the etravirine early access program in the United States.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100401
Title: Suboptimal etravirine activity is common during failure of nevirapine-based combination antiretroviral therapy in a cohort infected with non-B subtype HIV-1.
Journal: Current HIV research 20100401
Title: Using of nevirapine is associated with intermediate and reduced response to etravirine among HIV-infected patients who experienced virologic failure in a resource-limited setting.
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20100401
Title: Recent FDA approvals and changes.
Journal: AIDS patient care and STDs 20100401
Title: HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate.
Journal: Viruses 20100401
Title: Raltegravir, maraviroc, etravirine: an effective protease inhibitor and nucleoside reverse transcriptase inhibitor-sparing regimen for salvage therapy in HIV-infected patients with triple-class experience.
Journal: AIDS (London, England) 20100327
Title: Etravirine limits the emergence of darunavir and other protease inhibitor resistance-associated mutations in the DUET trials.
Journal: AIDS (London, England) 20100327
Title: Clinical implications of genotypic resistance to the newer antiretroviral drugs in HIV-1-infected patients with virological failure.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100315
Title: Impact of human leukocyte antigen-B*51-restricted cytotoxic T-lymphocyte pressure on mutation patterns of nonnucleoside reverse transcriptase inhibitor resistance.
Journal: AIDS (London, England) 20100313
Title: HIV RNA suppression rates after 24 weeks of treatment with etravirine, darunavir/ritonavir and raltegravir in the etravirine early access programme.
Journal: International journal of STD & AIDS 20100301
Title: Factors predictive of successful darunavir/ritonavir-based therapy in highly antiretroviral-experienced HIV-1-infected patients (the DARWEST study).
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20100301
Title: N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters 20100301
Title: N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters 20100301
Title: HIV type 1 antiretroviral resistance mutations in subtypes B, C, and F in the City of São Paulo, Brazil.
Journal: AIDS research and human retroviruses 20100301
Title: Short communication: evaluation of the effect of enfuvirtide in 11 HIV-1 vertically infected pediatric patients outside clinical trials.
Journal: AIDS research and human retroviruses 20100301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20100301
Title: Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies.
Journal: AIDS (London, England) 20100220
Title: TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1.
Journal: Antimicrobial agents and chemotherapy 20100201
Title: Low-abundance HIV species and their impact on mutational profiles in patients with virological failure on once-daily abacavir/lamivudine/zidovudine and tenofovir.
Journal: The Journal of antimicrobial chemotherapy 20100201
Title: Etravirine: A novel nonnucleoside reverse transcriptase inhibitor for managing human immunodeficiency virus infection.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100201
Title: Effects of hepatic impairment on the steady-state pharmacokinetics of etravirine 200 mg BID: an open-label, multiple-dose, controlled Phase I study in adults.
Journal: Clinical therapeutics 20100201
Title: HIV treatment information.
Journal: Project Inform perspective 20100201
Title: [Discovery and development of diarylpyrimidines (DAPYs) as next-generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100201
Title: [Establishment and application of a high-throughput screening assay for premature activation of HIV-1 precursors].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100201
Title: Etravirine resistance associated mutations in HIV-infected patients failing efavirenz or nevirapine in the Spanish antiretroviral resistance database.
Journal: AIDS (London, England) 20100128
Title: [Pharmacovigilance update].
Journal: Revue medicale suisse 20100120
Title: Sensitivity of V75I HIV-1 reverse transcriptase mutant selected in vitro by acyclovir to anti-HIV drugs.
Journal: AIDS (London, England) 20100116
Title: N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations.
Journal: AIDS (London, England) 20100116
Title: An investigation into the crystallisation behaviour of an amorphous cryomilled pharmaceutical material above and below the glass transition temperature.
Journal: Journal of pharmaceutical sciences 20100101
Title: Pharmacokinetics and drug-drug interactions of antiretrovirals: an update.
Journal: Antiviral research 20100101
Title: Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009).
Journal: Antiviral research 20100101
Title: Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents.
Journal: The Annals of pharmacotherapy 20100101
Title: Drug interactions with new and investigational antiretrovirals.
Journal: Clinical pharmacokinetics 20100101
Title: Is there any potential for first-line etravirine use? Analysis from a large data set of antiretroviral therapy-naive HIV-infected patients undergoing resistance test.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100101
Title: One-, two-, and three-class resistance among HIV-infected patients on antiretroviral therapy in private care clinics: Mumbai, India.
Journal: AIDS research and human retroviruses 20100101
Title: Towards a Patent Pool for HIV Medicines: The Background.
Journal: The open AIDS journal 20100101
Title: Pooling ARV Drug Patents: A Pro-Access Fitting Strategy?
Journal: The open AIDS journal 20100101
Title: Profile of etravirine for the treatment of HIV infection.
Journal: Therapeutics and clinical risk management 20100101
Title: Designing ARVs Patent Pool Up to Trade & Policy Evolutionary Dynamics.
Journal: The open AIDS journal 20100101
Title: Simplification of antiretroviral therapy with etravirine.
Journal: AIDS reviews 20100101
Title: Decreased NK Cell FcRgamma in HIV-1 infected individuals receiving combination antiretroviral therapy: a cross sectional study.
Journal: PloS one 20100101
Title: Effects of etravirine versus placebo on health-related quality of life in treatment-experienced HIV patients as measured by the functional assessment of human immunodeficiency virus infection (FAHI) questionnaire in the DUET trials.
Journal: HIV clinical trials 20100101
Title: The HIV-1 integrase mutations Y143C/R are an alternative pathway for resistance to Raltegravir and impact the enzyme functions.
Journal: PloS one 20100101
Title: Recent key advances in human immunodeficiency virus medicine and implications for China.
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Title: Use of newer antiretroviral agents, darunavir and etravirine with or without raltegravir, in pregnancy: a report of two cases.
Journal: Antiviral therapy 20100101
Title: Comparison of HIV-1 genotypic resistance test interpretation systems in predicting virological outcomes over time.
Journal: PloS one 20100101
Title: High performance liquid chromatography using UV detection for the simultaneous quantification of the new non-nucleoside reverse transcriptase inhibitor etravirine (TMC-125), and 4 protease inhibitors in human plasma.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Case report: HIV infection from a kidney transplant.
Journal: Transplantation proceedings 20100101
Title: Maraviroc in treatment-experienced patients with HIV-1 infection - experience from routine clinical practice.
Journal: European journal of medical research 20100101
Title: Pharmacokinetics of once-daily etravirine without and with once-daily darunavir/ritonavir in antiretroviral-naive HIV type-1-infected adults.
Journal: Antiviral therapy 20100101
Title: From bench to clinic: accessing promising investigational medications for patients with HIV infection in an urban family health center.
Journal: Journal of the American Board of Family Medicine : JABFM 20100101
Title: Etravirine: clinical review of a treatment option for HIV type-1-infected patients with non-nucleoside reverse transcriptase inhibitor resistance.
Journal: Antiviral therapy 20100101
Title: Clinical perspective on antiretroviral drug-drug interactions with the non-nucleoside reverse transcriptase inhibitor etravirine.
Journal: Antiviral therapy 20100101
Title: Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen.
Journal: Clinical epidemiology 20100101
Title: Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C.
Journal: Retrovirology 20100101
Title: Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV protease.
Journal: Retrovirology 20100101
Title: The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in children.
Journal: BMC pediatrics 20100101
Title: Genotypic evaluation of etravirine sensitivity of clinical human immunodeficiency virus type 1 (HIV-1) isolates carrying resistance mutations to nevirapine and efavirenz.
Journal: Acta clinica Belgica 20100101
Title: Progress in antiretroviral drug delivery using nanotechnology.
Journal: International journal of nanomedicine 20100101
Title: Impact of the background regimen on virologic response to etravirine: pooled 48-week analysis of DUET-1 and -2.
Journal: HIV clinical trials 20100101
Title: Efficacy and safety of etravirine at week 96 in treatment-experienced HIV type-1-infected patients in the DUET-1 and DUET-2 trials.
Journal: Antiviral therapy 20100101
Title: Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.
Journal: PloS one 20100101
Title: Early development of non-hodgkin lymphoma following initiation of newer class antiretroviral therapy among HIV-infected patients - implications for immune reconstitution.
Journal: AIDS research and therapy 20100101
Title: Mutations in the C-terminal region of the HIV-1 reverse transcriptase and their correlation with drug resistance associated mutations and antiviral treatment.
Journal: European journal of medical research 20100101
Title: Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009.
Journal: PloS one 20100101
Title: Clinical management of treatment-experienced, HIV/AIDS patients in the combination antiretroviral therapy era.
Journal: PharmacoEconomics 20100101
Title: Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.
Journal: Cholesterol 20100101
Title: Raltegravir in combination with other antiretroviral agents for the treatment of HIV infection.
Journal: Infection and drug resistance 20100101
Title: Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy.
Journal: Infection and drug resistance 20100101
Title: Role of etravirine in the management of treatment-experienced patients with human immunodeficiency virus type 1.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: Long-term treatment of patients with HIV-1: the role of atazanavir.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: The interaction between clopidogrel and proton pump inhibitors (PPI): is there any clinical relevance?
Journal: Clinical pharmacology : advances and applications 20100101
Title: Sustained HIV RNA suppression after switching from enfuvirtide to etravirine in the early access programme.
Journal: The Journal of antimicrobial chemotherapy 20091201
Title: Validation of an electrospray ionization LC-MS/MS method for quantitative analysis of raltegravir, etravirine, and 9 other antiretroviral agents in human plasma samples.
Journal: Therapeutic drug monitoring 20091201
Title: Risk of extended viral resistance in human immunodeficiency virus-1-infected Mozambican children after first-line treatment failure.
Journal: The Pediatric infectious disease journal 20091201
Title: Will etravirine work in patients failing nonnucleoside reverse transcriptase inhibitor-based treatment in southern Africa?
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Title: [Etravirine in highly treatment-experienced patients].
Journal: Enfermedades infecciosas y microbiologia clinica 20091201
Title: [Etravirine in first-line therapy].
Journal: Enfermedades infecciosas y microbiologia clinica 20091201
Title: [Safety and tolerability of etravirine].
Journal: Enfermedades infecciosas y microbiologia clinica 20091201
Title: [Etravirine drug interactions].
Journal: Enfermedades infecciosas y microbiologia clinica 20091201
Title: [Etravirine: genetic barrier and resistance development].
Journal: Enfermedades infecciosas y microbiologia clinica 20091201
Title: [Etravirine in special populations].
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Title: [Role of etravirine in combination antiretroviral therapy].
Journal: Enfermedades infecciosas y microbiologia clinica 20091201
Title: Efficacy and safety of etravirine in treatment-experienced, HIV-1 patients: pooled 48 week analysis of two randomized, controlled trials.
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Title: Raltegravir, etravirine and r-darunavir combination in adolescents with multidrug-resistant virus.
Journal: AIDS (London, England) 20091113
Title: Raltegravir, etravirine, and ritonavir-boosted darunavir: a safe and successful rescue regimen for multidrug-resistant HIV-1 infection.
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Title: Prevalence of etravirine mutations and impact on response to treatment in routine clinical care: the Swiss HIV Cohort Study (SHCS).
Journal: HIV medicine 20091101
Title: Minority variants associated with transmitted and acquired HIV-1 nonnucleoside reverse transcriptase inhibitor resistance: implications for the use of second-generation nonnucleoside reverse transcriptase inhibitors.
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Title: Efavirenz: a decade of clinical experience in the treatment of HIV.
Journal: The Journal of antimicrobial chemotherapy 20091101
Title: High rate of virologic suppression with raltegravir plus etravirine and darunavir/ritonavir among treatment-experienced patients infected with multidrug-resistant HIV: results of the ANRS 139 TRIO trial.
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Title: First-line regimen failure of antiretroviral therapy: a clinical and evidence-based approach.
Journal: Current opinion in HIV and AIDS 20091101
Title: Drugs in traditional drug classes (nucleoside reverse transcriptase inhibitor/nonnucleoside reverse transcriptase inhibitor/protease inhibitors) with activity against drug-resistant virus (tipranavir, darunavir, etravirine).
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Journal: Methods and findings in experimental and clinical pharmacology 20091101
Title: A novel LC-ESI-MS method for the simultaneous determination of etravirine, darunavir and ritonavir in human blood plasma.
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Journal: Journal de pharmacie de Belgique 20090901
Title: Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus.
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Title: Additional HIV-1 mutation patterns associated with reduced phenotypic susceptibility to etravirine in clinical samples.
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Journal: Contraception 20090701
Title: Etravirine plasma levels in a patient with decompensated liver disease.
Journal: AIDS (London, England) 20090619
Title: Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor.
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Title: Etravirine: new drug. Multidrug-resistant HIV: another option.
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Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20090501
Title: Etravirine-raltegravir, a marked interaction in HIV-1-infected patients: about four cases.
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Title: Etravirine, a next-generation nonnucleoside reverse-transcriptase inhibitor.
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Title: A LC-tandem MS assay for the simultaneous measurement of new antiretroviral agents: Raltegravir, maraviroc, darunavir, and etravirine.
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Title: Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.
Journal: International journal of antimicrobial agents 20090401
Title: Prediction of the virological response to etravirine in clinical practice: Comparison of three genotype algorithms.
Journal: Journal of medical virology 20090401
Title: Johnson & Johnson seeks full FDA approval for Intelence.
Journal: The AIDS reader 20090401
Title: Etravirine: a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant strains of HIV.
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Title: Gateways to clinical trials.
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Title: Pharmacokinetics of darunavir, etravirine and raltegravir in an HIV-infected patient on haemodialysis.
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Title: Efficacy of etravirine for treatment of acute HIV meningoencephalitis.
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Title: Etravirine and rilpivirine: nonnucleoside reverse transcriptase inhibitors with activity against human immunodeficiency virus type 1 strains resistant to previous nonnucleoside agents.
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Title: The fusion inhibitor enfuvirtide in recent antiretroviral strategies.
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Title: Quantification of etravirine (TMC125) in plasma, dried blood spots and peripheral blood mononuclear cell lysate by liquid chromatography tandem mass spectrometry.
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Title: Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants.
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Title: Pharmacologic aspects of new antiretroviral drugs.
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Title: Warfarin-antiretroviral interactions.
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Title: Raltegravir and etravirine are active against HIV type 1 group O.
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Title: Efficacy and safety of etravirine (TMC125) in treatment-experienced HIV-1-infected patients: 48-week results of a phase IIb trial.
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Title: Successful use of darunavir, etravirine, enfuvirtide and tenofovir/emtricitabine in pregnant woman with multiclass HIV resistance.
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Title: Efficacy and safety of darunavir and etravirine in an antiretroviral multi-experienced youth with vertically HIV-1 infection.
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Title: Role of atazanavir in the treatment of HIV infection.
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Title: Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients.
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Title: Drug interactions with new and investigational antiretrovirals.
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Title: Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use.
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Title: Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996-2008).
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Title: Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study.
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Title: Pharmacotherapy of pediatric and adolescent HIV infection.
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Journal: Therapeutics and clinical risk management 20090101
Title: Clinical pharmacokinetics and pharmacodynamics of etravirine.
Journal: Clinical pharmacokinetics 20090101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20090101
Title: Five-year follow up of genotypic resistance patterns in HIV-1 subtype C infected patients in Botswana after failure of thymidine analogue-based regimens.
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Title: Etravirine for HIV-I: addressing the limitations of the nonnucleoside reverse transcriptase inhibitor class.
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Title: Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes.
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Title: Progress in basic and clinical research on HIV resistance: report on the XVIII International HIV Drug Resistance Workshop.
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Title: Two standards of care for HIV: why are Africans being short-changed?
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Title: A Rough Set-Based Model of HIV-1 Reverse Transcriptase Resistome.
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Title: Canadian consensus guidelines for the optimal use of etravirine in the treatment of HIV-infected adults.
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Title: Raltegravir: The evidence of its therapeutic value in HIV-1 infection.
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Title: Etravirine (TMC-125): The evidence for its place in the treatment of HIV-1 infection.
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Title: Profile of darunavir in the management of treatment-experienced HIV patients.
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Title: Pharmacologic and nonpharmacologic options for the management of HIV infection during pregnancy.
Journal: HIV/AIDS (Auckland, N.Z.) 20090101
Title: Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.
Journal: Journal of medicinal chemistry 20081211
Title: An HPLC-PDA method for the simultaneous quantification of the HIV integrase inhibitor raltegravir, the new nonnucleoside reverse transcriptase inhibitor etravirine, and 11 other antiretroviral agents in the plasma of HIV-infected patients.
Journal: Therapeutic drug monitoring 20081201
Title: Etravirine: the renaissance of non-nucleoside reverse transcriptase inhibitors.
Journal: Expert opinion on pharmacotherapy 20081201
Title: No hepatotoxicity found for etravirine.
Journal: AIDS patient care and STDs 20081201
Title: Two studies look at Intelence.
Journal: Project Inform perspective 20081201
Title: Phenotypic impact of resistance mutations on etravirine susceptibility in HIV patients with prior failure to nonnucleoside analogues.
Journal: AIDS (London, England) 20081112
Title: Prevalence of etravirine-associated mutations in clinical samples with resistance to nevirapine and efavirenz.
Journal: The Journal of antimicrobial chemotherapy 20081101
Title: Adverse cutaneous reactions associated with the newest antiretroviral drugs in patients with human immunodeficiency virus infection.
Journal: The Journal of antimicrobial chemotherapy 20081101
Title: Impact of reverse transcriptase resistance on the efficacy of TMC125 (etravirine) with two nucleoside reverse transcriptase inhibitors in protease inhibitor-naïve, nonnucleoside reverse transcriptase inhibitor-experienced patients: study TMC125-C227.
Journal: HIV medicine 20081101
Title: Pharmacologic aspects of new antiretroviral drugs.
Journal: Current infectious disease reports 20081101
Title: Darunavir-etravirine-raltegravir as salvage combination therapy in a heavily pretreated HIV-infected patient.
Journal: AIDS patient care and STDs 20081101
Title: [Role of the new molecules in antiretroviral therapy. Position of raltegravir].
Journal: Enfermedades infecciosas y microbiologia clinica 20081101
Title: A pharmacokinetic study of etravirine (TMC125) co-administered with ranitidine and omeprazole in HIV-negative volunteers.
Journal: British journal of clinical pharmacology 20081001
Title: Shifting paradigms: the resistance profile of etravirine.
Journal: The Journal of antimicrobial chemotherapy 20081001
Title: Safety, tolerability, and preliminary efficacy of 48 weeks of etravirine therapy in a phase IIb dose-ranging study involving treatment-experienced patients with HIV-1 infection.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001
Title: Effects of different meal compositions and fasted state on the oral bioavailability of etravirine.
Journal: Pharmacotherapy 20081001
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20081001
Title: [Darunavir in patients with advanced HIV and multiresistance. The POWER, DUET and BENCHMRK studies].
Journal: Enfermedades infecciosas y microbiologia clinica 20081001
Title: [Resistance to darunavir].
Journal: Enfermedades infecciosas y microbiologia clinica 20081001
Title: Evolution of genetic diversity and drug resistance mutations in HIV-1 among untreated patients from Mali between 2005 and 2006.
Journal: The Journal of antimicrobial chemotherapy 20080901
Title: A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations.
Journal: Antiviral research 20080901
Title: Evaluating the role of etravirine in the second-line antiretroviral therapy after failing an initial non-nucleoside reverse transcriptase inhibitor-based regimen in a resource-limited setting.
Journal: Current HIV research 20080901
Title: HIV infection in the elderly.
Journal: Clinical interventions in aging 20080901
Title: Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel.
Journal: JAMA 20080806
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Journal: Journal of medical virology 20080801
Title: Etravirine for the treatment of HIV infection.
Journal: Expert review of anti-infective therapy 20080801
Title: Combating HIV resistance - focus on darunavir.
Journal: Therapeutics and clinical risk management 20080801
Title: Combating Non-nucleoside Reverse Transcriptase Inhibitor Resistance with a Focus On Etravirine (Intelence) for HIV-1 Infection.
Journal: P & T : a peer-reviewed journal for formulary management 20080801
Title: New treatment options for HIV salvage patients: an overview of second generation PIs, NNRTIs, integrase inhibitors and CCR5 antagonists.
Journal: The Journal of infection 20080701
Title: How developing world concerns need to be part of drug development plans: a case study of four emerging antiretrovirals.
Journal: Drug discovery today 20080701
Title: Etravirine(Intelence) for HIV infection.
Journal: The Medical letter on drugs and therapeutics 20080616
Title: Etravirine has no effect on QT and corrected QT interval in HIV-negative volunteers.
Journal: The Annals of pharmacotherapy 20080601
Title: Potential for new antiretrovirals to address unmet needs in the management of HIV-1 infection.
Journal: AIDS patient care and STDs 20080601
Title: New protease inhibitors and non-nucleoside reverse transcriptase inhibitors.
Journal: Journal of HIV therapy 20080601
Title: Is there a role for etravirine in patients with Nonnucleoside reverse transcriptase inhibitor resistance?
Journal: AIDS (London, England) 20080511
Title: Updated prevalence of genotypic resistance among HIV-1 positive patients naïve to antiretroviral therapy: a single center analysis.
Journal: Journal of medical virology 20080501
Title: Successful rescue therapy with Raltegravir (MK-0518) and Etravirine (TMC125) in an hiv-infected patient failing all four classes of antiretroviral drugs.
Journal: AIDS patient care and STDs 20080501
Title: Complexity of interactions between voriconazole and antiretroviral agents.
Journal: The Annals of pharmacotherapy 20080501
Title: Pharmacologic characteristics of investigational and recently approved agents for the treatment of HIV.
Journal: Current opinion in HIV and AIDS 20080501
Title: Contraceptive patch: new labeling.
Journal: Nursing for women's health 20080401
Title: Raltegravir: first in class HIV integrase inhibitor.
Journal: Therapeutics and clinical risk management 20080401
Title: Report from the 15th Retrovirus Conference. Etravirine resistance: baseline prevalence and proposed criteria for 'vircotype'.
Journal: AIDS clinical care 20080401
Title: Pharmacokinetic and pharmacodynamic study of the concomitant administration of methadone and TMC125 in HIV-negative volunteers.
Journal: Journal of clinical pharmacology 20080301
Title: 48-week data released for etravirine (TMC125).
Journal: AIDS patient care and STDs 20080301
Title: FDA approval: etravirine.
Journal: AIDS clinical care 20080301
Title: [New drugs for HIV infection].
Journal: Revue de l'infirmiere 20080301
Title: FDA notifications. FDA grants accelerated approval for etravirine.
Journal: AIDS alert 20080301
Title: 3D-QSAR models on clinically relevant K103N mutant HIV-1 reverse transcriptase obtained from two strategic considerations.
Journal: Bioorganic & medicinal chemistry letters 20080201
Title: FDA approves new HIV drug after priority review.
Journal: AIDS patient care and STDs 20080201
Title: Hemorrhagic cardiomyopathy in male mice treated with an NNRTI: the role of vitamin K.
Journal: Toxicologic pathology 20080201
Title: The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001-2006) in Portugal.
Journal: Retrovirology 20080101
Title: Etravirine.
Journal: Drugs of today (Barcelona, Spain : 1998) 20080101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20080101
Title: Highlights of the 15th Conference on Retroviruses and Opportunistic Infections. Advances in antiretroviral therapy.
Journal: Topics in HIV medicine : a publication of the International AIDS Society, USA 20080101
Title: New drugs: Etravirine, sinecatechins, and desvenlafaxine succinate.
Journal: Journal of the American Pharmacists Association : JAPhA 20080101
Title: Prevalence and risk factors for etravirine resistance among patients failing on non-nucleoside reverse transcriptase inhibitors.
Journal: Antiviral therapy 20080101
Title: Single- and multiple-dose pharmacokinetics of etravirine administered as two different formulations in HIV-1-infected patients.
Journal: Antiviral therapy 20080101
Title: Emerging resistance profiles of newly approved antiretroviral drugs.
Journal: Topics in HIV medicine : a publication of the International AIDS Society, USA 20080101
Title: Successful rescue therapy with a darunavir/ritonavir and etravirine antiretroviral regimen in a child with vertically acquired multidrug-resistant HIV-1.
Journal: Antiviral therapy 20080101
Title: Etravirine.
Journal: Drugs 20080101
Title: Pharmacokinetics of elvitegravir and etravirine following coadministration of ritonavir-boosted elvitegravir and etravirine.
Journal: Antiviral therapy 20080101
Title: Broad advances in understanding HIV resistance to antiretrovirals: report on the XVII International HIV Drug Resistance Workshop.
Journal: Antiviral therapy 20080101
Title: Raltegravir in the management of HIV-infected patients.
Journal: Drug design, development and therapy 20080101
Title: Prevalence of etravirine (TMC-125) resistance mutations in HIV-infected patients with prior experience of non-nucleoside reverse transcriptase inhibitors.
Journal: The Journal of antimicrobial chemotherapy 20071201
Title: Resistance testing methodologies and mechanisms of resistance.
Journal: Journal of HIV therapy 20071201
Title: From docking false-positive to active anti-HIV agent.
Journal: Journal of medicinal chemistry 20071101
Title: Antiviral drugs in the treatment of AIDS: what is in the pipeline ?
Journal: European journal of medical research 20071015
Title: FDA accepts NDA for priority review of TMC125.
Journal: AIDS patient care and STDs 20071001
Title: Lessons Learned From 2 Patients With Multidrug-Resistant HIV-1 Infection Successfully Treated With a Darunavir-Containing Antiretroviral Treatment Regimen.
Journal: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20070901
Title: NDA submitted for TMC125.
Journal: AIDS patient care and STDs 20070901
Title: Report from the XVI International HIV Drug Resistance Workshop.
Journal: AIDS clinical care 20070801
Title: Pharmacokinetics and antiretroviral response to darunavir/ritonavir and etravirine combination in patients with high-level viral resistance.
Journal: AIDS (London, England) 20070711
Title: No patient left behind--better treatments for resistant HIV infection.
Journal: Lancet (London, England) 20070707
Title: Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial.
Journal: Lancet (London, England) 20070707
Title: Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial.
Journal: Lancet (London, England) 20070707
Title: Drug resistant HIV.
Journal: BMJ (Clinical research ed.) 20070602
Title: Advances in HIV therapeutics: the 14th CROI.
Journal: The AIDS reader 20070501
Title: Efficacy and safety of etravirine (TMC125) in patients with highly resistant HIV-1: primary 24-week analysis.
Journal: AIDS (London, England) 20070330
Title: TMC125 (etravirine), a second generation non-nucleoside reverse transcriptase inhibitor.
Journal: AIDS alert 20070201
Title: Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Journal: Biochemical and biophysical research communications 20070112
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20070101
Title: Anti-HIV agents. The need for etravirine (TMC125).
Journal: TreatmentUpdate 20070101
Title: Anti-HIV agents. Etravirine--interactions with some medications.
Journal: TreatmentUpdate 20070101
Title: Anti-HIV agents. Effectiveness of etravirine in treatment-experienced PHAs.
Journal: TreatmentUpdate 20070101
Title: Anti-HIV agents. Brain side effects not common with etravirine.
Journal: TreatmentUpdate 20070101
Title: Modelling-based prediction of clinical benefits from etravirine in the TMC125-C223 trial.
Journal: HIV clinical trials 20070101
Title: Expanded drug access: etravirine (formerly TMC-125).
Journal: The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20070101
Title: Antiretroviral treatment of HIV infection: Swedish recommendations 2007.
Journal: Scandinavian journal of infectious diseases 20070101
Title: Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers.
Journal: Antiviral therapy 20070101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20070101
Title: Clinical implications of mutations at reverse transcriptase codon 135 on response to NNRTI-based therapy.
Journal: The open virology journal 20070101
Title: Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters 20061101
Title: Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol.
Journal: PLoS pathogens 20061101
Title: British HIV Association (BHIVA) guidelines for the treatment of HIV-infected adults with antiretroviral therapy (2006).
Journal: HIV medicine 20061101
Title: TMC125 study highlights failing NNRTI regimen task.
Journal: IAPAC monthly 20061101
Title: AIDS 2006 - XVI International Conference. Time to deliver.
Journal: IDrugs : the investigational drugs journal 20061001
Title: The latest in antiretroviral therapy.
Journal: Drug news & perspectives 20061001
Title: The clinical pharmacology of antiretrovirals in development.
Journal: Expert opinion on drug metabolism & toxicology 20060601
Title: Report from the 13th retrovirus conference. New data on TMC114 and TMC125.
Journal: AIDS clinical care 20060401
Title: Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters 20060201
Title: Next-generation HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Current opinion in investigational drugs (London, England : 2000) 20060201
Title: Etravirine: R165335, TMC 125, TMC-125, TMC125.
Journal: Drugs in R&D 20060101
Title: Drug interactions. Interactions with TMC114 and TMC125.
Journal: TreatmentUpdate 20060101
Title: New drugs.
Journal: HIV medicine 20050701
Title: Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors.
Journal: Progress in biophysics and molecular biology 20050601
Title: The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations.
Journal: Journal of the American Chemical Society 20050525
Title: Emerging anti-HIV drugs.
Journal: Expert opinion on emerging drugs 20050501
Title: From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to etravirine (TMC125): fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal: Journal of medicinal chemistry 20050324
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050101
Title: TMC125: new results, large phase III trial begins.
Journal: AIDS treatment news 20050101
Title: TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1.
Journal: Antimicrobial agents and chemotherapy 20041201
Title: New non-nucleoside reverse transcriptase inhibitors (NNRTIs) in development for the treatment of HIV infections.
Journal: Current opinion in pharmacology 20041001
Title: A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides.
Journal: Antimicrobial agents and chemotherapy 20041001
Title: HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches.
Journal: The international journal of biochemistry & cell biology 20040901
Title: Effect of stereo and regiochemistry towards wild and multidrug resistant HIV-1 virus: viral potency of chiral PETT derivatives.
Journal: Biochemical pharmacology 20040515
Title: Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants.
Journal: Journal of medicinal chemistry 20040506
Title: TMC125: important one-year trial now recruiting in U.S.
Journal: AIDS treatment news 20040430
Title: TMC-125 Tibotec.
Journal: Current opinion in investigational drugs (London, England : 2000) 20040201
Title: TMC 125 possibly effective against NNRTI-resistant HIV.
Journal: IAPAC monthly 20040101
Title: Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1.
Journal: Current topics in medicinal chemistry 20040101
Title: Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors.
Journal: Current topics in medicinal chemistry 20040101
Title: Correlations between factors determining the pharmacokinetics and antiviral activity of HIV-1 non-nucleoside reverse transcriptase inhibitors of the diaryltriazine and diarylpyrimidine classes of compounds.
Journal: Drugs in R&D 20040101
Title: Behind 'AIDS breakthrough' headlines, December 2004: important research, not so new.
Journal: AIDS treatment news 20040101
Title: TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen.
Journal: AIDS (London, England) 20031205
Title: An open-label assessment of TMC 125--a new, next-generation NNRTI, for 7 days in HIV-1 infected individuals with NNRTI resistance.
Journal: AIDS (London, England) 20031205
Title: A randomized, double-blind, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral naive, HIV-1 infected subjects.
Journal: AIDS (London, England) 20031121
Title: Validation of a model for the complex of HIV-1 reverse transcriptase with nonnucleoside inhibitor TMC125.
Journal: Journal of the American Chemical Society 20030521
Title: One as potent as five.
Journal: AIDS (London, England) 20020816
Title: Drugs in development.
Journal: AIDS patient care and STDs 20020501
Title: Researchers explore new anti-HIV agents.
Journal: JAMA 20020403
Title: Promising new agents on the horizon.
Journal: AIDS clinical care 20020301
Title: Tests on new NNRTI show strong potency.
Journal: AIDS alert 20020201
Title: TMC125 shows promise.
Journal: AIDS patient care and STDs 20020201
Title: Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues.
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